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Intracranial Hemorrhage, Hypertensive

MedGen UID:
155952
•Concept ID:
C0751891
•
Pathologic Function
Synonyms: Hemorrhage, Hypertensive Intracranial; Hemorrhage, Intracranial Hypertensive; Hemorrhages, Hypertensive Intracranial; Hemorrhages, Intracranial Hypertensive; Hypertensive Hemorrhage, Intracranial; Hypertensive Hemorrhages, Intracranial; Hypertensive Intracranial Hemorrhage; Hypertensive Intracranial Hemorrhages; Intracranial Hemorrhages, Hypertensive; Intracranial Hypertensive Hemorrhage; Intracranial Hypertensive Hemorrhages

Definition

Bleeding within the SKULL that is caused by systemic HYPERTENSION, usually in association with INTRACRANIAL ARTERIOSCLEROSIS. Hypertensive hemorrhages are most frequent in the BASAL GANGLIA; CEREBELLUM; PONS; and THALAMUS; but may also involve the CEREBRAL CORTEX, subcortical white matter, and other brain structures. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntracranial Hemorrhage, Hypertensive

Professional guidelines

PubMed

Endoscopic third ventriculostomy in the management of communicating hydrocephalus: a preliminary study.
Hailong F, Guangfu H, Haibin T, Hong P, Yong C, Weidong L, Dongdong Z
J Neurosurg 2008 Nov;109(5):923-30. doi: 10.3171/JNS/2008/109/11/0923. PMID: 18976086

Recent clinical studies

Etiology

Current management of spontaneous intracerebral haemorrhage.
Dastur CK, Yu W
Stroke Vasc Neurol 2017 Mar;2(1):21-29. Epub 2017 Feb 24 doi: 10.1136/svn-2016-000047. PMID: 28959487Free PMC Article
The Case.
Mishra R
Camb Q Healthc Ethics 2016 Apr;25(2):330. doi: 10.1017/S0963180115000626. PMID: 26957457
The diagnosis and management of cerebrovascular disease in diabetes.
Phipps MS, Jastreboff AM, Furie K, Kernan WN
Curr Diab Rep 2012 Jun;12(3):314-23. doi: 10.1007/s11892-012-0271-x. PMID: 22492061
Cerebral hemodynamic changes following carotid endarterectomy: 'cerebral hyperperfusion syndrome'.
Noorani A, Sadat U, Gaunt ME
Expert Rev Neurother 2010 Feb;10(2):217-23. doi: 10.1586/ern.10.2. PMID: 20136378
Intracerebral hemorrhage and hypertension.
Sessa M
Neurol Sci 2008 Sep;29 Suppl 2:S258-9. doi: 10.1007/s10072-008-0956-8. PMID: 18690511

Diagnosis

Surgical treatment of spontaneous brainstem hemorrhage: A case report.
Hao G, Xu Z, Zhu J
Medicine (Baltimore) 2019 Dec;98(51):e18430. doi: 10.1097/MD.0000000000018430. PMID: 31861010Free PMC Article
The Case.
Mishra R
Camb Q Healthc Ethics 2016 Apr;25(2):330. doi: 10.1017/S0963180115000626. PMID: 26957457
Emergency neurological life support: intracerebral hemorrhage.
Andrews CM, Jauch EC, Hemphill JC 3rd, Smith WS, Weingart SD
Neurocrit Care 2012 Sep;17 Suppl 1:S37-46. doi: 10.1007/s12028-012-9757-2. PMID: 22965322
Clinical syndromes and management of intracerebral hemorrhage.
Ko SB, Choi HA, Lee K
Curr Atheroscler Rep 2012 Aug;14(4):307-13. doi: 10.1007/s11883-012-0251-2. PMID: 22538430
Hypertension in the elderly: what is the goal blood pressure target and how can this be attained?
Carlberg B, Nilsson PM
Curr Hypertens Rep 2010 Oct;12(5):331-4. doi: 10.1007/s11906-010-0138-y. PMID: 20711758

Therapy

Observation on the value of evidence-based nursing in perioperative period of patients with hypertensive intracerebral hemorrhage and the reduction of complications.
Li X, Han X, Pang J, Liu H
Minerva Surg 2022 Jun;77(3):304-306. Epub 2021 Aug 3 doi: 10.23736/S2724-5691.21.09037-7. PMID: 34342406
Current management of spontaneous intracerebral haemorrhage.
Dastur CK, Yu W
Stroke Vasc Neurol 2017 Mar;2(1):21-29. Epub 2017 Feb 24 doi: 10.1136/svn-2016-000047. PMID: 28959487Free PMC Article
Emergency neurological life support: intracerebral hemorrhage.
Andrews CM, Jauch EC, Hemphill JC 3rd, Smith WS, Weingart SD
Neurocrit Care 2012 Sep;17 Suppl 1:S37-46. doi: 10.1007/s12028-012-9757-2. PMID: 22965322
The diagnosis and management of cerebrovascular disease in diabetes.
Phipps MS, Jastreboff AM, Furie K, Kernan WN
Curr Diab Rep 2012 Jun;12(3):314-23. doi: 10.1007/s11892-012-0271-x. PMID: 22492061
Cerebral hemodynamic changes following carotid endarterectomy: 'cerebral hyperperfusion syndrome'.
Noorani A, Sadat U, Gaunt ME
Expert Rev Neurother 2010 Feb;10(2):217-23. doi: 10.1586/ern.10.2. PMID: 20136378

Prognosis

Minimally invasive surgeries for spontaneous hypertensive intracerebral hemorrhage (MISICH): a multicenter randomized controlled trial.
Xu X, Zhang H, Zhang J, Luo M, Wang Q, Zhao Y, Gan Z, Xu B, Chen X; MISICH study team
BMC Med 2024 Jun 13;22(1):244. doi: 10.1186/s12916-024-03468-y. PMID: 38867192Free PMC Article
What did Joseph Stalin really die of? A reappraisal of his illness, death, and autopsy findings.
Barth RF, Brodsky SV, Ruzic M
Cardiovasc Pathol 2019 May-Jun;40:55-58. Epub 2019 Feb 20 doi: 10.1016/j.carpath.2019.02.003. PMID: 30870795
Different Strokes: A management dilemma.
Gujjar AR, El-Tigani M, Lal D, Kakaria AK, Al-Asmi AR
Sultan Qaboos Univ Med J 2018 May;18(2):e202-e207. Epub 2018 Sep 9 doi: 10.18295/squmj.2018.18.02.013. PMID: 30210851Free PMC Article
Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people.
Rapsomaniki E, Timmis A, George J, Pujades-Rodriguez M, Shah AD, Denaxas S, White IR, Caulfield MJ, Deanfield JE, Smeeth L, Williams B, Hingorani A, Hemingway H
Lancet 2014 May 31;383(9932):1899-911. doi: 10.1016/S0140-6736(14)60685-1. PMID: 24881994Free PMC Article
Acidosis of severe falciparum malaria: heading for a shock?
Maitland K, Newton CR
Trends Parasitol 2005 Jan;21(1):11-6. doi: 10.1016/j.pt.2004.10.010. PMID: 15639735

Clinical prediction guides

Minimally invasive surgeries for spontaneous hypertensive intracerebral hemorrhage (MISICH): a multicenter randomized controlled trial.
Xu X, Zhang H, Zhang J, Luo M, Wang Q, Zhao Y, Gan Z, Xu B, Chen X; MISICH study team
BMC Med 2024 Jun 13;22(1):244. doi: 10.1186/s12916-024-03468-y. PMID: 38867192Free PMC Article
Observation on the value of evidence-based nursing in perioperative period of patients with hypertensive intracerebral hemorrhage and the reduction of complications.
Li X, Han X, Pang J, Liu H
Minerva Surg 2022 Jun;77(3):304-306. Epub 2021 Aug 3 doi: 10.23736/S2724-5691.21.09037-7. PMID: 34342406
Fluoxetine for motor recovery after acute intracerebral hemorrhage, the FMRICH trial.
Marquez-Romero JM, Reyes-Martínez M, Huerta-Franco MR, Ruiz-Franco A, Silos H, Arauz A
Clin Neurol Neurosurg 2020 Mar;190:105656. Epub 2019 Dec 28 doi: 10.1016/j.clineuro.2019.105656. PMID: 31896491
Experimental hypertension increases spontaneous intracerebral hemorrhages in a mouse model of cerebral amyloidosis.
Passos GF, Kilday K, Gillen DL, Cribbs DH, Vasilevko V
J Cereb Blood Flow Metab 2016 Feb;36(2):399-404. Epub 2015 Oct 2 doi: 10.1177/0271678X15606720. PMID: 26661173Free PMC Article
Acidosis of severe falciparum malaria: heading for a shock?
Maitland K, Newton CR
Trends Parasitol 2005 Jan;21(1):11-6. doi: 10.1016/j.pt.2004.10.010. PMID: 15639735

Recent systematic reviews

Neuroendoscopic Surgery versus Craniotomy for Supratentorial Hypertensive Intracerebral Hemorrhage: A Systematic Review and Meta-Analysis.
Sun S, Li Y, Zhang H, Gao H, Zhou X, Xu Y, Yan K, Wang X
World Neurosurg 2020 Feb;134:477-488. Epub 2019 Nov 15 doi: 10.1016/j.wneu.2019.10.115. PMID: 31669683
Efficacy and safety of minimal invasive surgery treatment in hypertensive intracerebral hemorrhage: a systematic review and meta-analysis.
Tang Y, Yin F, Fu D, Gao X, Lv Z, Li X
BMC Neurol 2018 Sep 3;18(1):136. doi: 10.1186/s12883-018-1138-9. PMID: 30176811Free PMC Article
Effects of Intensive Blood Pressure Lowering on Intracerebral Hemorrhage Outcomes: A Meta-Analysis of Randomized Controlled Trials.
Ma J, Li H, Liu Y, You C, Huang S, Ma L
Turk Neurosurg 2015;25(4):544-51. doi: 10.5137/1019-5149.JTN.9270-13.0. PMID: 26242330
Intensive blood pressure reduction in acute intracerebral hemorrhage: a meta-analysis.
Tsivgoulis G, Katsanos AH, Butcher KS, Boviatsis E, Triantafyllou N, Rizos I, Alexandrov AV
Neurology 2014 Oct 21;83(17):1523-9. Epub 2014 Sep 19 doi: 10.1212/WNL.0000000000000917. PMID: 25239836
Hypertension and the post-carotid endarterectomy cerebral hyperperfusion syndrome.
Bouri S, Thapar A, Shalhoub J, Jayasooriya G, Fernando A, Franklin IJ, Davies AH
Eur J Vasc Endovasc Surg 2011 Feb;41(2):229-37. Epub 2010 Dec 4 doi: 10.1016/j.ejvs.2010.10.016. PMID: 21131217

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