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Subfoveal choroidal neovascularization

MedGen UID:
1616433
Concept ID:
C4531251
Finding
HPO: HP:0031241

Definition

A type of choroidal neovascularization in which the area of neovascularization overlaps with the center of the fovea. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSubfoveal choroidal neovascularization

Professional guidelines

PubMed

Thompson JT
Retina 2011 May;31(5):819-20. doi: 10.1097/IAE.0b013e31820c83d9. PMID: 21386755
Smith BT, Joseph DP, Grand MG
Curr Opin Ophthalmol 2007 May;18(3):240-4. doi: 10.1097/ICU.0b013e32810c8e05. PMID: 17435433
Shiraga F, Takasu I, Shiragami C
Semin Ophthalmol 1998 Mar;13(1):31-9. doi: 10.3109/08820539809066080. PMID: 9567010

Recent clinical studies

Etiology

Wykoff CC, Brown DM, Reed K, Berliner AJ, Gerstenblith AT, Breazna A, Abraham P, Fein JG, Chu KW, Clark WL, Leal S, Schmelter T, Hirshberg B, Yancopoulos GD, Vitti R; CANDELA Study Investigators
JAMA Ophthalmol 2023 Sep 1;141(9):834-842. doi: 10.1001/jamaophthalmol.2023.2421. PMID: 37535382
Holz FG, Oleksy P, Ricci F, Kaiser PK, Kiefer J, Schmitz-Valckenberg S; COLUMBUS-AMD Study Group
Ophthalmology 2022 Jan;129(1):54-63. Epub 2021 May 3 doi: 10.1016/j.ophtha.2021.04.031. PMID: 33957183
Woo SJ, Veith M, Hamouz J, Ernest J, Zalewski D, Studnicka J, Vajas A, Papp A, Gabor V, Luu J, Matuskova V, Yoon YH, Pregun T, Kim T, Shin D, Bressler NM
JAMA Ophthalmol 2021 Jan 1;139(1):68-76. doi: 10.1001/jamaophthalmol.2020.5053. PMID: 33211076Free PMC Article
Cao XS, Peng XY, You QS, Zhang YP, Jonas JB
Ophthalmologica 2014;231(4):221-5. Epub 2014 Mar 5 doi: 10.1159/000357114. PMID: 24603209
Heier JS, Brown DM, Chong V, Korobelnik JF, Kaiser PK, Nguyen QD, Kirchhof B, Ho A, Ogura Y, Yancopoulos GD, Stahl N, Vitti R, Berliner AJ, Soo Y, Anderesi M, Groetzbach G, Sommerauer B, Sandbrink R, Simader C, Schmidt-Erfurth U; VIEW 1 and VIEW 2 Study Groups
Ophthalmology 2012 Dec;119(12):2537-48. Epub 2012 Oct 17 doi: 10.1016/j.ophtha.2012.09.006. PMID: 23084240

Diagnosis

Holz FG, Oleksy P, Ricci F, Kaiser PK, Kiefer J, Schmitz-Valckenberg S; COLUMBUS-AMD Study Group
Ophthalmology 2022 Jan;129(1):54-63. Epub 2021 May 3 doi: 10.1016/j.ophtha.2021.04.031. PMID: 33957183
Woo SJ, Veith M, Hamouz J, Ernest J, Zalewski D, Studnicka J, Vajas A, Papp A, Gabor V, Luu J, Matuskova V, Yoon YH, Pregun T, Kim T, Shin D, Bressler NM
JAMA Ophthalmol 2021 Jan 1;139(1):68-76. doi: 10.1001/jamaophthalmol.2020.5053. PMID: 33211076Free PMC Article
Cao XS, Peng XY, You QS, Zhang YP, Jonas JB
Ophthalmologica 2014;231(4):221-5. Epub 2014 Mar 5 doi: 10.1159/000357114. PMID: 24603209
Heier JS, Brown DM, Chong V, Korobelnik JF, Kaiser PK, Nguyen QD, Kirchhof B, Ho A, Ogura Y, Yancopoulos GD, Stahl N, Vitti R, Berliner AJ, Soo Y, Anderesi M, Groetzbach G, Sommerauer B, Sandbrink R, Simader C, Schmidt-Erfurth U; VIEW 1 and VIEW 2 Study Groups
Ophthalmology 2012 Dec;119(12):2537-48. Epub 2012 Oct 17 doi: 10.1016/j.ophtha.2012.09.006. PMID: 23084240
Shiraga F, Takasu I, Shiragami C
Semin Ophthalmol 1998 Mar;13(1):31-9. doi: 10.3109/08820539809066080. PMID: 9567010

Therapy

Wykoff CC, Brown DM, Reed K, Berliner AJ, Gerstenblith AT, Breazna A, Abraham P, Fein JG, Chu KW, Clark WL, Leal S, Schmelter T, Hirshberg B, Yancopoulos GD, Vitti R; CANDELA Study Investigators
JAMA Ophthalmol 2023 Sep 1;141(9):834-842. doi: 10.1001/jamaophthalmol.2023.2421. PMID: 37535382
Holz FG, Oleksy P, Ricci F, Kaiser PK, Kiefer J, Schmitz-Valckenberg S; COLUMBUS-AMD Study Group
Ophthalmology 2022 Jan;129(1):54-63. Epub 2021 May 3 doi: 10.1016/j.ophtha.2021.04.031. PMID: 33957183
Woo SJ, Veith M, Hamouz J, Ernest J, Zalewski D, Studnicka J, Vajas A, Papp A, Gabor V, Luu J, Matuskova V, Yoon YH, Pregun T, Kim T, Shin D, Bressler NM
JAMA Ophthalmol 2021 Jan 1;139(1):68-76. doi: 10.1001/jamaophthalmol.2020.5053. PMID: 33211076Free PMC Article
Heier JS, Brown DM, Chong V, Korobelnik JF, Kaiser PK, Nguyen QD, Kirchhof B, Ho A, Ogura Y, Yancopoulos GD, Stahl N, Vitti R, Berliner AJ, Soo Y, Anderesi M, Groetzbach G, Sommerauer B, Sandbrink R, Simader C, Schmidt-Erfurth U; VIEW 1 and VIEW 2 Study Groups
Ophthalmology 2012 Dec;119(12):2537-48. Epub 2012 Oct 17 doi: 10.1016/j.ophtha.2012.09.006. PMID: 23084240
Landy J, Brown GC
Curr Opin Ophthalmol 2003 Jun;14(3):163-8. doi: 10.1097/00055735-200306000-00010. PMID: 12777937

Prognosis

Borodoker N, Spaide RF, Maranan L, Murray J, Freund KB, Slakter JS, Sorenson JA, Yannuzzi LA, Guyer DR, Fisher YL
Am J Ophthalmol 2002 Feb;133(2):211-4. doi: 10.1016/s0002-9394(01)01341-1. PMID: 11812424
Vander JF
Curr Opin Ophthalmol 2000 Jun;11(3):159-65. doi: 10.1097/00055735-200006000-00001. PMID: 10977220
Fleckner MR, Hochman MA, Buzney SM, Weiter JJ, Tolentino FI, Khadem JJ
Int Ophthalmol Clin 2000 Winter;40(1):201-14. doi: 10.1097/00004397-200001000-00019. PMID: 10713926
Shiraga F, Takasu I, Shiragami C
Semin Ophthalmol 1998 Mar;13(1):31-9. doi: 10.3109/08820539809066080. PMID: 9567010
Custis PH, Bressler SB, Bressler NM
Curr Opin Ophthalmol 1993 Jun;4(3):7-18. doi: 10.1097/00055735-199306000-00003. PMID: 10151009

Clinical prediction guides

Wykoff CC, Brown DM, Reed K, Berliner AJ, Gerstenblith AT, Breazna A, Abraham P, Fein JG, Chu KW, Clark WL, Leal S, Schmelter T, Hirshberg B, Yancopoulos GD, Vitti R; CANDELA Study Investigators
JAMA Ophthalmol 2023 Sep 1;141(9):834-842. doi: 10.1001/jamaophthalmol.2023.2421. PMID: 37535382
Cao XS, Peng XY, You QS, Zhang YP, Jonas JB
Ophthalmologica 2014;231(4):221-5. Epub 2014 Mar 5 doi: 10.1159/000357114. PMID: 24603209
Parodi MB, Iacono P, Cascavilla M, Zucchiatti I, Kontadakis DS, Bandello F
Invest Ophthalmol Vis Sci 2010 Sep;51(9):4358-61. Epub 2010 Apr 7 doi: 10.1167/iovs.10-5237. PMID: 20375343
Borodoker N, Spaide RF, Maranan L, Murray J, Freund KB, Slakter JS, Sorenson JA, Yannuzzi LA, Guyer DR, Fisher YL
Am J Ophthalmol 2002 Feb;133(2):211-4. doi: 10.1016/s0002-9394(01)01341-1. PMID: 11812424
Fleckner MR, Hochman MA, Buzney SM, Weiter JJ, Tolentino FI, Khadem JJ
Int Ophthalmol Clin 2000 Winter;40(1):201-14. doi: 10.1097/00004397-200001000-00019. PMID: 10713926

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