U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal vasa vasorum morphology

MedGen UID:
1622451
•Concept ID:
C4531102
•
Anatomical Abnormality
HPO: HP:0031465

Definition

A structural anomaly of vasa vasorum, which are defined as small blood vessels that supply or drain the walls of larger arteries and veins, delivering nutrients and oxygen as well as removing systemic waste products. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal vasa vasorum morphology

Professional guidelines

PubMed

Combining nanotechnology with current biomedical knowledge for the vascular imaging and treatment of atherosclerosis.
Slevin M, Badimon L, Grau-Olivares M, Ramis M, Sendra J, Morrison M, Krupinski J
Mol Biosyst 2010 Mar;6(3):444-50. Epub 2009 Nov 12 doi: 10.1039/b916175a. PMID: 20174673

Recent clinical studies

Etiology

Role of lipids and intraplaque hypoxia in the formation of neovascularization in atherosclerosis.
Chistiakov DA, Melnichenko AA, Myasoedova VA, Grechko AV, Orekhov AN
Ann Med 2017 Dec;49(8):661-677. Epub 2017 Aug 22 doi: 10.1080/07853890.2017.1366041. PMID: 28797175
Association between coronary microvascular function and the vasa vasorum in patients with early coronary artery disease.
Park KH, Sun T, Diez-Delhoyo F, Liu Z, Yang SW, Lennon RJ, Herrmann J, Gulati R, Rodriguez-Porcel M, Lerman LO, Lerman A
Atherosclerosis 2016 Oct;253:144-149. Epub 2016 Aug 26 doi: 10.1016/j.atherosclerosis.2016.08.031. PMID: 27626971
Role of Microvascular Tone and Extracellular Matrix Contraction in the Regulation of Interstitial Fluid: Implications for Aortic Dissection.
Mallat Z, Tedgui A, Henrion D
Arterioscler Thromb Vasc Biol 2016 Sep;36(9):1742-7. Epub 2016 Jul 21 doi: 10.1161/ATVBAHA.116.307909. PMID: 27444198
Abdominal aortic aneurysm and histological, clinical, radiological correlation.
Rodella LF, Rezzani R, Bonomini F, Peroni M, Cocchi MA, Hirtler L, Bonardelli S
Acta Histochem 2016 Apr;118(3):256-62. Epub 2016 Feb 5 doi: 10.1016/j.acthis.2016.01.007. PMID: 26858185
Homocysteine Metabolism, Atherosclerosis, and Diseases of Aging.
McCully KS
Compr Physiol 2015 Dec 15;6(1):471-505. doi: 10.1002/cphy.c150021. PMID: 26756640

Diagnosis

Prognostic Links Between OCT-Delineated Coronary Morphologies and Coronary Functional Abnormalities in Patients With INOCA.
Nishimiya K, Suda A, Fukui K, Hao K, Takahashi J, Matsumoto Y, Mitsuishi K, Watanabe T, Ohyama K, Sugisawa J, Tsuchiya S, Satoh K, Shindo T, Godo S, Kikuchi Y, Shiroto T, Yasuda S, Shimokawa H
JACC Cardiovasc Interv 2021 Mar 22;14(6):606-618. doi: 10.1016/j.jcin.2020.12.025. PMID: 33736768
Role of lipids and intraplaque hypoxia in the formation of neovascularization in atherosclerosis.
Chistiakov DA, Melnichenko AA, Myasoedova VA, Grechko AV, Orekhov AN
Ann Med 2017 Dec;49(8):661-677. Epub 2017 Aug 22 doi: 10.1080/07853890.2017.1366041. PMID: 28797175
Association between coronary microvascular function and the vasa vasorum in patients with early coronary artery disease.
Park KH, Sun T, Diez-Delhoyo F, Liu Z, Yang SW, Lennon RJ, Herrmann J, Gulati R, Rodriguez-Porcel M, Lerman LO, Lerman A
Atherosclerosis 2016 Oct;253:144-149. Epub 2016 Aug 26 doi: 10.1016/j.atherosclerosis.2016.08.031. PMID: 27626971
Inflamed temporal artery: histologic findings in 354 biopsies, with clinical correlations.
Cavazza A, Muratore F, Boiardi L, Restuccia G, Pipitone N, Pazzola G, Tagliavini E, Ragazzi M, Rossi G, Salvarani C
Am J Surg Pathol 2014 Oct;38(10):1360-70. doi: 10.1097/PAS.0000000000000244. PMID: 25216320
Combining nanotechnology with current biomedical knowledge for the vascular imaging and treatment of atherosclerosis.
Slevin M, Badimon L, Grau-Olivares M, Ramis M, Sendra J, Morrison M, Krupinski J
Mol Biosyst 2010 Mar;6(3):444-50. Epub 2009 Nov 12 doi: 10.1039/b916175a. PMID: 20174673

Therapy

Pathological Analysis of Vascularization of the Arterialized Veins in Failed Arteriovenous Fistulae.
Chen Q, Liang L, Zhang Z, Du J, Tang L, Cao W, Kong X, Xu D
J Vasc Interv Radiol 2022 Aug;33(8):904-912.e1. Epub 2022 May 20 doi: 10.1016/j.jvir.2022.05.004. PMID: 35605817
Impaired angiogenesis and extracellular matrix metabolism in autosomal-dominant hyper-IgE syndrome.
Dmitrieva NI, Walts AD, Nguyen DP, Grubb A, Zhang X, Wang X, Ping X, Jin H, Yu Z, Yu ZX, Yang D, Schwartzbeck R, Dalgard CL, Kozel BA, Levin MD, Knutsen RH, Liu D, Milner JD, López DB, O'Connell MP, Lee CR, Myles IA, Hsu AP, Freeman AF, Holland SM, Chen G, Boehm M
J Clin Invest 2020 Aug 3;130(8):4167-4181. doi: 10.1172/JCI135490. PMID: 32369445Free PMC Article
Small-vessel vasculitis surrounding an uninflamed temporal artery and isolated vasa vasorum vasculitis of the temporal artery: two subsets of giant cell arteritis.
Restuccia G, Cavazza A, Boiardi L, Pipitone N, Macchioni P, Bajocchi G, Catanoso MG, Muratore F, Ghinoi A, Magnani L, Cimino L, Salvarani C
Arthritis Rheum 2012 Feb;64(2):549-56. doi: 10.1002/art.33362. PMID: 21953306
Combining nanotechnology with current biomedical knowledge for the vascular imaging and treatment of atherosclerosis.
Slevin M, Badimon L, Grau-Olivares M, Ramis M, Sendra J, Morrison M, Krupinski J
Mol Biosyst 2010 Mar;6(3):444-50. Epub 2009 Nov 12 doi: 10.1039/b916175a. PMID: 20174673
The morphology of the human newborn ductus arteriosus: a reappraisal of its structure and closure with special reference to prostaglandin E1 therapy.
Silver MM, Freedom RM, Silver MD, Olley PM
Hum Pathol 1981 Dec;12(12):1123-36. doi: 10.1016/s0046-8177(81)80333-4. PMID: 7199511

Prognosis

Prognostic Links Between OCT-Delineated Coronary Morphologies and Coronary Functional Abnormalities in Patients With INOCA.
Nishimiya K, Suda A, Fukui K, Hao K, Takahashi J, Matsumoto Y, Mitsuishi K, Watanabe T, Ohyama K, Sugisawa J, Tsuchiya S, Satoh K, Shindo T, Godo S, Kikuchi Y, Shiroto T, Yasuda S, Shimokawa H
JACC Cardiovasc Interv 2021 Mar 22;14(6):606-618. doi: 10.1016/j.jcin.2020.12.025. PMID: 33736768
Impaired angiogenesis and extracellular matrix metabolism in autosomal-dominant hyper-IgE syndrome.
Dmitrieva NI, Walts AD, Nguyen DP, Grubb A, Zhang X, Wang X, Ping X, Jin H, Yu Z, Yu ZX, Yang D, Schwartzbeck R, Dalgard CL, Kozel BA, Levin MD, Knutsen RH, Liu D, Milner JD, López DB, O'Connell MP, Lee CR, Myles IA, Hsu AP, Freeman AF, Holland SM, Chen G, Boehm M
J Clin Invest 2020 Aug 3;130(8):4167-4181. doi: 10.1172/JCI135490. PMID: 32369445Free PMC Article
Role of lipids and intraplaque hypoxia in the formation of neovascularization in atherosclerosis.
Chistiakov DA, Melnichenko AA, Myasoedova VA, Grechko AV, Orekhov AN
Ann Med 2017 Dec;49(8):661-677. Epub 2017 Aug 22 doi: 10.1080/07853890.2017.1366041. PMID: 28797175
Inflamed temporal artery: histologic findings in 354 biopsies, with clinical correlations.
Cavazza A, Muratore F, Boiardi L, Restuccia G, Pipitone N, Pazzola G, Tagliavini E, Ragazzi M, Rossi G, Salvarani C
Am J Surg Pathol 2014 Oct;38(10):1360-70. doi: 10.1097/PAS.0000000000000244. PMID: 25216320
The year in echocardiography.
Weyman AE
J Am Coll Cardiol 2009 Apr 28;53(17):1558-67. doi: 10.1016/j.jacc.2009.01.042. PMID: 19389569

Clinical prediction guides

Role of lipids and intraplaque hypoxia in the formation of neovascularization in atherosclerosis.
Chistiakov DA, Melnichenko AA, Myasoedova VA, Grechko AV, Orekhov AN
Ann Med 2017 Dec;49(8):661-677. Epub 2017 Aug 22 doi: 10.1080/07853890.2017.1366041. PMID: 28797175
Association between coronary microvascular function and the vasa vasorum in patients with early coronary artery disease.
Park KH, Sun T, Diez-Delhoyo F, Liu Z, Yang SW, Lennon RJ, Herrmann J, Gulati R, Rodriguez-Porcel M, Lerman LO, Lerman A
Atherosclerosis 2016 Oct;253:144-149. Epub 2016 Aug 26 doi: 10.1016/j.atherosclerosis.2016.08.031. PMID: 27626971
Role of Microvascular Tone and Extracellular Matrix Contraction in the Regulation of Interstitial Fluid: Implications for Aortic Dissection.
Mallat Z, Tedgui A, Henrion D
Arterioscler Thromb Vasc Biol 2016 Sep;36(9):1742-7. Epub 2016 Jul 21 doi: 10.1161/ATVBAHA.116.307909. PMID: 27444198
Homocysteine Metabolism, Atherosclerosis, and Diseases of Aging.
McCully KS
Compr Physiol 2015 Dec 15;6(1):471-505. doi: 10.1002/cphy.c150021. PMID: 26756640
Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage.
Virmani R, Kolodgie FD, Burke AP, Finn AV, Gold HK, Tulenko TN, Wrenn SP, Narula J
Arterioscler Thromb Vasc Biol 2005 Oct;25(10):2054-61. Epub 2005 Jul 21 doi: 10.1161/01.ATV.0000178991.71605.18. PMID: 16037567

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...