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Focal subretinal deposits

MedGen UID:
1625190
Concept ID:
C4531066
Finding
HPO: HP:0031529

Definition

Deposits accumulating between the outer retina and the retinal pigment epithelium and that have a focal distribution. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFocal subretinal deposits

Professional guidelines

PubMed

Kijlstra A, La Heij E, Hendrikse F
Ocul Immunol Inflamm 2005 Feb;13(1):3-11. doi: 10.1080/09273940590909185. PMID: 15804763

Recent clinical studies

Etiology

Banerjee M, Nayak S, Kumar S, Bhayana AA, Kumar V
Surv Ophthalmol 2023 Jul-Aug;68(4):591-600. Epub 2023 Mar 17 doi: 10.1016/j.survophthal.2023.03.002. PMID: 36933772
Zhang Y, Sadda SR, Sarraf D, Swain TA, Clark ME, Sloan KR, Warriner WE, Owsley C, Curcio CA
Invest Ophthalmol Vis Sci 2022 Feb 1;63(2):32. doi: 10.1167/iovs.63.2.32. PMID: 35212721Free PMC Article
Birtel J, von Landenberg C, Gliem M, Gliem C, Reimann J, Kunz WS, Herrmann P, Betz C, Caswell R, Nesbitt V, Kornblum C, Charbel Issa P
Ophthalmol Retina 2022 Jan;6(1):65-79. Epub 2021 Jul 10 doi: 10.1016/j.oret.2021.02.017. PMID: 34257060
Spaide RF, Yannuzzi L, Freund KB, Mullins R, Stone E
Retina 2019 Jan;39(1):12-26. doi: 10.1097/IAE.0000000000002362. PMID: 30312263
Mansour AM, Arevalo JF, Badal J, Moorthy RS, Shah GK, Zegarra H, Pulido JS, Charbaji A, Amselem L, Lavaque AJ, Casella A, Ahmad B, Paschall JG, Caimi A, Staurenghi G
Ophthalmology 2014 Oct;121(10):1925-32. Epub 2014 Jun 18 doi: 10.1016/j.ophtha.2014.04.007. PMID: 24950591

Diagnosis

Zhang Y, Sadda SR, Sarraf D, Swain TA, Clark ME, Sloan KR, Warriner WE, Owsley C, Curcio CA
Invest Ophthalmol Vis Sci 2022 Feb 1;63(2):32. doi: 10.1167/iovs.63.2.32. PMID: 35212721Free PMC Article
Birtel J, von Landenberg C, Gliem M, Gliem C, Reimann J, Kunz WS, Herrmann P, Betz C, Caswell R, Nesbitt V, Kornblum C, Charbel Issa P
Ophthalmol Retina 2022 Jan;6(1):65-79. Epub 2021 Jul 10 doi: 10.1016/j.oret.2021.02.017. PMID: 34257060
Van Rysselberge C, Balikova I, Judice L, Makhoul D, Postelmans L
Retin Cases Brief Rep 2022 May 1;16(3):333-337. Epub 2020 Feb 4 doi: 10.1097/ICB.0000000000000970. PMID: 32028449
Spaide RF, Yannuzzi L, Freund KB, Mullins R, Stone E
Retina 2019 Jan;39(1):12-26. doi: 10.1097/IAE.0000000000002362. PMID: 30312263
Hogg RE
Optom Vis Sci 2014 Aug;91(8):854-9. doi: 10.1097/OPX.0000000000000287. PMID: 24950032

Therapy

Kvanta A, Rangaswamy N, Holopigian K, Watters C, Jennings N, Liew MSH, Bigelow C, Grosskreutz C, Burstedt M, Venkataraman A, Westman S, Geirsdottir A, Stasi K, André H
Nat Commun 2024 Sep 10;15(1):7438. doi: 10.1038/s41467-024-51575-4. PMID: 39256350Free PMC Article
Michalak SM, Bonafede L, Kelly MP, Cai CX, Chen X
J AAPOS 2021 Apr;25(2):128-131. Epub 2021 Mar 15 doi: 10.1016/j.jaapos.2020.12.004. PMID: 33737053
Madhusudhan S, Hussain A, Sahni JN
Digit J Ophthalmol 2013;19(4):59-63. Epub 2013 Dec 30 doi: 10.5693/djo.02.2013.09.001. PMID: 24459458Free PMC Article
Sabet-Peyman J, Salehi-Had H, Fawzi AA
Ophthalmic Surg Lasers Imaging 2012 Jun 28;43 Online:e58-61. doi: 10.3928/15428877-20120621-01. PMID: 22731855
Kijlstra A, La Heij E, Hendrikse F
Ocul Immunol Inflamm 2005 Feb;13(1):3-11. doi: 10.1080/09273940590909185. PMID: 15804763

Prognosis

Reiter GS, Told R, Schranz M, Baumann L, Mylonas G, Sacu S, Pollreisz A, Schmidt-Erfurth U
Invest Ophthalmol Vis Sci 2020 Jun 3;61(6):11. doi: 10.1167/iovs.61.6.11. PMID: 32503052Free PMC Article
Zhang Y, Wang X, Sadda SR, Clark ME, Witherspoon CD, Spaide RF, Owsley C, Curcio CA
Ophthalmol Retina 2020 Mar;4(3):274-283. Epub 2019 Oct 31 doi: 10.1016/j.oret.2019.10.012. PMID: 31924545Free PMC Article
Spaide RF, Yannuzzi L, Freund KB, Mullins R, Stone E
Retina 2019 Jan;39(1):12-26. doi: 10.1097/IAE.0000000000002362. PMID: 30312263
Mansour AM, Arevalo JF, Badal J, Moorthy RS, Shah GK, Zegarra H, Pulido JS, Charbaji A, Amselem L, Lavaque AJ, Casella A, Ahmad B, Paschall JG, Caimi A, Staurenghi G
Ophthalmology 2014 Oct;121(10):1925-32. Epub 2014 Jun 18 doi: 10.1016/j.ophtha.2014.04.007. PMID: 24950591
Hogg RE
Optom Vis Sci 2014 Aug;91(8):854-9. doi: 10.1097/OPX.0000000000000287. PMID: 24950032

Clinical prediction guides

Guan W, Xiao Y, Zhao H, Hu F, Chen C, Peng X
Clin Exp Ophthalmol 2023 Mar;51(2):144-153. Epub 2023 Jan 4 doi: 10.1111/ceo.14197. PMID: 36567492
Zhang Y, Sadda SR, Sarraf D, Swain TA, Clark ME, Sloan KR, Warriner WE, Owsley C, Curcio CA
Invest Ophthalmol Vis Sci 2022 Feb 1;63(2):32. doi: 10.1167/iovs.63.2.32. PMID: 35212721Free PMC Article
Mansour AM, Arevalo JF, Badal J, Moorthy RS, Shah GK, Zegarra H, Pulido JS, Charbaji A, Amselem L, Lavaque AJ, Casella A, Ahmad B, Paschall JG, Caimi A, Staurenghi G
Ophthalmology 2014 Oct;121(10):1925-32. Epub 2014 Jun 18 doi: 10.1016/j.ophtha.2014.04.007. PMID: 24950591
Hogg RE
Optom Vis Sci 2014 Aug;91(8):854-9. doi: 10.1097/OPX.0000000000000287. PMID: 24950032
Saade C, Smith RT
Clin Exp Ophthalmol 2014 Dec;42(9):865-74. Epub 2014 Aug 7 doi: 10.1111/ceo.12353. PMID: 24803342

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