U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Hyperdeviation

MedGen UID:
1630968
•Concept ID:
C4068932
•
Disease or Syndrome
HPO: HP:0025587

Definition

A type of strabismus in which the visual axis of one eye is higher than that of the other. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHyperdeviation

Professional guidelines

PubMed

Deficiency of depression in adduction: clinical characteristics and surgical management of the "inverted Brown pattern".
Marsh JD, Yilmaz PT, Guyton DL
J AAPOS 2016 Feb;20(1):7-11. doi: 10.1016/j.jaapos.2015.10.011. PMID: 26917064
Superior oblique palsy: diagnosis and treatment.
Flanders M, Draper J
Can J Ophthalmol 1990 Feb;25(1):17-24. PMID: 2328432

Recent clinical studies

Etiology

Age-related nonparalytic hypertropia: Clinical features.
Oohira A
Acta Ophthalmol 2024 Sep;102(6):683-689. Epub 2024 Mar 25 doi: 10.1111/aos.16682. PMID: 38525840
Superior oblique tuck-effectiveness in reducing vertical deviations when performed as a primary versus secondary procedure in superior oblique paresis.
Malem AH, Somner JE, Novitskya ES, Vivian AJ
Eye (Lond) 2023 Dec;37(17):3656-3660. Epub 2023 May 16 doi: 10.1038/s41433-023-02576-y. PMID: 37193830Free PMC Article
Approach to patient with diplopia.
Margolin E
J Neurol Sci 2020 Oct 15;417:117055. Epub 2020 Aug 5 doi: 10.1016/j.jns.2020.117055. PMID: 32777577
Adjustable Bilateral Superior Oblique Tendon Advancement for Bilateral Fourth Nerve Palsy.
Bata BM, Leske DA, Holmes JM
Am J Ophthalmol 2017 Jun;178:115-121. Epub 2017 Mar 31 doi: 10.1016/j.ajo.2017.03.028. PMID: 28366647Free PMC Article
Interventions for dissociated vertical deviation.
Hatt SR, Wang X, Holmes JM
Cochrane Database Syst Rev 2015 Nov 20;2015(11):CD010868. doi: 10.1002/14651858.CD010868.pub2. PMID: 26587695Free PMC Article

Diagnosis

Age-related nonparalytic hypertropia: Clinical features.
Oohira A
Acta Ophthalmol 2024 Sep;102(6):683-689. Epub 2024 Mar 25 doi: 10.1111/aos.16682. PMID: 38525840
Inferior oblique anterior transposition according to a different grading scale for hyperdeviation with inferior oblique overaction.
Gunduz A, Ozturk E, Firat M
Can J Ophthalmol 2023 Aug;58(4):287-294. Epub 2022 Mar 10 doi: 10.1016/j.jcjo.2022.02.006. PMID: 35278372
Role of a Standardized Prism Under Cover Test in the Assessment of Dissociated Vertical Deviation.
Klaehn LD, Hatt SR, Leske DA, Holmes JM
Strabismus 2018 Mar;26(1):1-5. Epub 2018 Feb 2 doi: 10.1080/09273972.2017.1391850. PMID: 29393712Free PMC Article
Relationship between static ocular counterroll and Bielschowsky head tilt phenomenon.
Hamasaki I, Hasebe S, Furuse T, Ohtsuki H
Invest Ophthalmol Vis Sci 2010 Jan;51(1):201-6. Epub 2009 Aug 6 doi: 10.1167/iovs.08-3035. PMID: 19661233
Childhood ocular myasthenia gravis.
Kim JH, Hwang JM, Hwang YS, Kim KJ, Chae J
Ophthalmology 2003 Jul;110(7):1458-62. doi: 10.1016/S0161-6420(03)00460-3. PMID: 12867410

Therapy

Ocular motility changes and diplopia in sutured versus unsutured implantation of the Baerveldt glaucoma device.
Islamaj E, Jordaan-Kuip CP, De Waard PWT, Vermeer KA, Lemij HG
Acta Ophthalmol 2021 Sep;99(6):e949-e955. Epub 2021 Feb 11 doi: 10.1111/aos.14707. PMID: 33576161Free PMC Article
Interventions for dissociated vertical deviation.
Hatt SR, Wang X, Holmes JM
Cochrane Database Syst Rev 2015 Nov 20;2015(11):CD010868. doi: 10.1002/14651858.CD010868.pub2. PMID: 26587695Free PMC Article
Inferior oblique transposition onto the equator: the role of the equator in development of contralateral inferior oblique overaction.
Kim SH, Na JH, Cho YA
J Pediatr Ophthalmol Strabismus 2012 Mar-Apr;49(2):98-102. Epub 2011 Aug 16 doi: 10.3928/01913913-20110809-02. PMID: 21838213
Unilateral inferior oblique muscle myectomy and recession in the treatment of inferior oblique muscle overaction: a longitudinal study.
Shipman T, Burke J
Eye (Lond) 2003 Nov;17(9):1013-8. doi: 10.1038/sj.eye.6700488. PMID: 14704751
Childhood ocular myasthenia gravis.
Kim JH, Hwang JM, Hwang YS, Kim KJ, Chae J
Ophthalmology 2003 Jul;110(7):1458-62. doi: 10.1016/S0161-6420(03)00460-3. PMID: 12867410

Prognosis

Age-related nonparalytic hypertropia: Clinical features.
Oohira A
Acta Ophthalmol 2024 Sep;102(6):683-689. Epub 2024 Mar 25 doi: 10.1111/aos.16682. PMID: 38525840
Ocular motility changes and diplopia in sutured versus unsutured implantation of the Baerveldt glaucoma device.
Islamaj E, Jordaan-Kuip CP, De Waard PWT, Vermeer KA, Lemij HG
Acta Ophthalmol 2021 Sep;99(6):e949-e955. Epub 2021 Feb 11 doi: 10.1111/aos.14707. PMID: 33576161Free PMC Article
Effect of inferior oblique anterior transposition in correcting vertical hyperdeviation in primary position.
Gunduz A, Fırat M, Ozsoy E, Cankaya C
Can J Ophthalmol 2019 Feb;54(1):75-82. Epub 2018 Apr 2 doi: 10.1016/j.jcjo.2018.01.035. PMID: 30851778
Adjustable Bilateral Superior Oblique Tendon Advancement for Bilateral Fourth Nerve Palsy.
Bata BM, Leske DA, Holmes JM
Am J Ophthalmol 2017 Jun;178:115-121. Epub 2017 Mar 31 doi: 10.1016/j.ajo.2017.03.028. PMID: 28366647Free PMC Article
Eye hyperdeviation in mouse cerebellar mutants is comparable to the gravity-dependent component of human downbeat nystagmus.
Stahl JS, Oommen BS
Prog Brain Res 2008;171:503-8. doi: 10.1016/S0079-6123(08)00672-9. PMID: 18718346

Clinical prediction guides

Inferior oblique anterior transposition according to a different grading scale for hyperdeviation with inferior oblique overaction.
Gunduz A, Ozturk E, Firat M
Can J Ophthalmol 2023 Aug;58(4):287-294. Epub 2022 Mar 10 doi: 10.1016/j.jcjo.2022.02.006. PMID: 35278372
Approach to patient with diplopia.
Margolin E
J Neurol Sci 2020 Oct 15;417:117055. Epub 2020 Aug 5 doi: 10.1016/j.jns.2020.117055. PMID: 32777577
Effect of inferior oblique anterior transposition in correcting vertical hyperdeviation in primary position.
Gunduz A, Fırat M, Ozsoy E, Cankaya C
Can J Ophthalmol 2019 Feb;54(1):75-82. Epub 2018 Apr 2 doi: 10.1016/j.jcjo.2018.01.035. PMID: 30851778
Eye hyperdeviation in mouse cerebellar mutants is comparable to the gravity-dependent component of human downbeat nystagmus.
Stahl JS, Oommen BS
Prog Brain Res 2008;171:503-8. doi: 10.1016/S0079-6123(08)00672-9. PMID: 18718346
Childhood ocular myasthenia gravis.
Kim JH, Hwang JM, Hwang YS, Kim KJ, Chae J
Ophthalmology 2003 Jul;110(7):1458-62. doi: 10.1016/S0161-6420(03)00460-3. PMID: 12867410

Recent systematic reviews

Interventions for dissociated vertical deviation.
Hatt SR, Wang X, Holmes JM
Cochrane Database Syst Rev 2015 Nov 20;2015(11):CD010868. doi: 10.1002/14651858.CD010868.pub2. PMID: 26587695Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...