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Abnormal inferior oblique muscle physiology

MedGen UID:: 1632780
•Concept ID:: C4703406
•: Disease or Syndrome

HPO:	HP:0025596

Definition

A functional anomaly of the inferior oblique muscle, an extraocular muscle that has its origin on the maxillary bone just posterior to the inferior medial orbital rim and lateral to the nasolacrimal canal and that is innervated by the inferior branch of the oculomotor nerve. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAbnormal inferior oblique muscle physiology

Phenotypic abnormality
- Abnormality of the eye
  - Abnormal eye physiology
    - Abnormal extraocular muscle physiology
      - Abnormal oblique muscle physiology
        Abnormal inferior oblique muscle physiology
        Inferior oblique muscle overaction
        Inferior oblique muscle weakness
        Inferior oblique muscle restriction
        Inferior oblique muscle underaction

Professional guidelines

PubMed

Phenotype, genotype, and management of congenital fibrosis of extraocular muscles type 1 in 16 Chinese families.

Chen M, Huang R, Zhang Y, Zhu DJ, Shu Q, Xun P, Zhang J, Gu P, Li L
Graefes Arch Clin Exp Ophthalmol 2023 Mar;261(3):879-889. Epub 2022 Sep 23 doi: 10.1007/s00417-022-05830-3. PMID: 36138147 Free PMC Article

The diagnosis and treatment of infantile nystagmus syndrome (INS).

Khanna S, Dell'Osso LF
ScientificWorldJournal 2006 Oct 30;6:1385-97. doi: 10.1100/tsw.2006.248. PMID: 17086344 Free PMC Article

The diagnosis and treatment of bilateral masked superior oblique palsy.

Kushner BJ
Am J Ophthalmol 1988 Feb 15;105(2):186-94. doi: 10.1016/0002-9394(88)90184-5. PMID: 3277437

See all (9)

Recent clinical studies

Etiology

Repair of the Malpositioned Lower Lid.

Chan D, Sokoya M, Ducic Y
Facial Plast Surg 2017 Dec;33(6):598-605. Epub 2017 Dec 1 doi: 10.1055/s-0037-1608711. PMID: 29195240

Congenital cranial dysinnervation disorders.

Singh A, Pandey PK, Agrawal A, Mittal SK, Rana KM, Bahuguna C
Int Ophthalmol 2017 Dec;37(6):1369-1381. Epub 2016 Nov 11 doi: 10.1007/s10792-016-0388-z. PMID: 27837354

Guillain-Barré syndrome.

Gurwood AS, Drake J
Optometry 2006 Nov;77(11):540-6. doi: 10.1016/j.optm.2006.06.014. PMID: 17145565

Ocular choristomas.

Mansour AM, Barber JC, Reinecke RD, Wang FM
Surv Ophthalmol 1989 Mar-Apr;33(5):339-58. doi: 10.1016/0039-6257(89)90011-8. PMID: 2655139

Strabismus in childhood.

O'Neill JF
Pediatr Ann 1977 Feb;6(2):10-1, 15, 18-9 passim. doi: 10.3928/0090-4481-19770201-04. PMID: 834479

See all (278)

Diagnosis

Ophthalmoplegia and Congenital Cranial Dysinnervation Disorders.

Oystreck DT
J Binocul Vis Ocul Motil 2018 Jan-Mar;68(1):31-33. Epub 2018 Jan 31 doi: 10.1080/2576117X.2017.1416242. PMID: 30196776

Repair of the Malpositioned Lower Lid.

Chan D, Sokoya M, Ducic Y
Facial Plast Surg 2017 Dec;33(6):598-605. Epub 2017 Dec 1 doi: 10.1055/s-0037-1608711. PMID: 29195240

The anatomy and physiology of the ocular motor system.

Horn AK, Leigh RJ
Handb Clin Neurol 2011;102:21-69. doi: 10.1016/B978-0-444-52903-9.00008-X. PMID: 21601062

Guillain-Barré syndrome.

Gurwood AS, Drake J
Optometry 2006 Nov;77(11):540-6. doi: 10.1016/j.optm.2006.06.014. PMID: 17145565

Infantile exotropia.

Biglan AW, Davis JS, Cheng KP, Pettapiece MC
J Pediatr Ophthalmol Strabismus 1996 Mar-Apr;33(2):79-84. doi: 10.3928/0191-3913-19960301-04. PMID: 8965243

See all (279)

Therapy

Concentric or monopolar electrode for jitter determination in orbicularis oculi.

Oliveira Santos M, Swash M, de Carvalho M
Clin Neurophysiol 2018 Dec;129(12):2552-2556. Epub 2018 Oct 26 doi: 10.1016/j.clinph.2018.09.024. PMID: 30388614

Diagnostic use of botulinum toxin in patients with Duane syndrome.

Dawson EL, Maino A, Lee JP
Strabismus 2010 Mar;18(1):21-3. doi: 10.3109/09273970903580199. PMID: 20230203

Clinical evidence of extraocular muscle fiber-type specificity of botulinum toxin.

Stahl JS, Averbuch-Heller L, Remler BF, Leigh RJ
Neurology 1998 Oct;51(4):1093-9. doi: 10.1212/wnl.51.4.1093. PMID: 9781535

Ocular myasthenia gravis. A critical review of clinical and pathophysiological aspects.

Sommer N, Melms A, Weller M, Dichgans J
Doc Ophthalmol 1993;84(4):309-33. doi: 10.1007/BF01215447. PMID: 8156854

A new variant of blepharospasm.

Elston JS
J Neurol Neurosurg Psychiatry 1992 May;55(5):369-71. doi: 10.1136/jnnp.55.5.369. PMID: 1602309 Free PMC Article

See all (81)

Prognosis

Repair of the Malpositioned Lower Lid.

Chan D, Sokoya M, Ducic Y
Facial Plast Surg 2017 Dec;33(6):598-605. Epub 2017 Dec 1 doi: 10.1055/s-0037-1608711. PMID: 29195240

Congenital cranial dysinnervation disorders.

Singh A, Pandey PK, Agrawal A, Mittal SK, Rana KM, Bahuguna C
Int Ophthalmol 2017 Dec;37(6):1369-1381. Epub 2016 Nov 11 doi: 10.1007/s10792-016-0388-z. PMID: 27837354

Strabismus in craniosynostosis.

Rosenberg JB, Tepper OM, Medow NB
J Pediatr Ophthalmol Strabismus 2013 May-Jun;50(3):140-8. Epub 2012 Nov 20 doi: 10.3928/01913913-20121113-02. PMID: 23163259

The anatomy and physiology of the ocular motor system.

Horn AK, Leigh RJ
Handb Clin Neurol 2011;102:21-69. doi: 10.1016/B978-0-444-52903-9.00008-X. PMID: 21601062

Guillain-Barré syndrome.

Gurwood AS, Drake J
Optometry 2006 Nov;77(11):540-6. doi: 10.1016/j.optm.2006.06.014. PMID: 17145565

See all (131)

Clinical prediction guides

The Role of Extraocular Muscle Pulleys in Incomitant Non-Paralytic Strabismus.

Clark RA
Middle East Afr J Ophthalmol 2015 Jul-Sep;22(3):279-85. doi: 10.4103/0974-9233.159698. PMID: 26180464 Free PMC Article

The anatomy and physiology of the ocular motor system.

Horn AK, Leigh RJ
Handb Clin Neurol 2011;102:21-69. doi: 10.1016/B978-0-444-52903-9.00008-X. PMID: 21601062

Strabismus and eye muscle function.

Lennerstrand G
Acta Ophthalmol Scand 2007 Nov;85(7):711-23. doi: 10.1111/j.1600-0420.2007.00853.x. PMID: 17944625

Oculonasal synkinesis.

Guyuron B, Bokhari F, Galloway DV, Thomas T
Plast Reconstr Surg 1994 Aug;94(2):251-3. doi: 10.1097/00006534-199408000-00005. PMID: 8041815

Ocular myopathies.

Tomé FM, Fardeau M
Pathol Res Pract 1985 Jul;180(1):19-27. doi: 10.1016/S0344-0338(85)80070-4. PMID: 4034429

See all (148)

Recent systematic reviews

Oculomotor functions in focal dystonias: A systematic review.

Hirsig A, Barbey C, Schüpbach MWM, Bargiotas P
Acta Neurol Scand 2020 May;141(5):359-367. Epub 2020 Feb 12 doi: 10.1111/ane.13224. PMID: 31990980

Clinical and histologic ocular findings in pompe disease.

Yanovitch TL, Banugaria SG, Proia AD, Kishnani PS
J Pediatr Ophthalmol Strabismus 2010 Jan-Feb;47(1):34-40. Epub 2010 Jan 21 doi: 10.3928/01913913-20100106-08. PMID: 20128552

See all (2)

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Abnormal inferior oblique muscle physiology

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

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Clinical resources

Practice guidelines

Consumer resources

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