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Physical urticaria

MedGen UID:
1639813
•Concept ID:
C4551831
•
Disease or Syndrome
Synonym: physical urticaria
SNOMED CT: Physical urticaria (402601007)
 
HPO: HP:0410134
Monarch Initiative: MONDO:0006599

Definition

Urticaria caused by physical agents, such as heat, cold, light, friction. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPhysical urticaria

Professional guidelines

PubMed

Physical urticaria: Clinical features, pathogenesis, diagnostic work-up, and management.
McSweeney SM, Christou EAA, Maurer M, Grattan CE, Tziotzios C, McGrath JA
J Am Acad Dermatol 2023 Aug;89(2):324-337. Epub 2023 Mar 30 doi: 10.1016/j.jaad.2023.02.062. PMID: 37001733
Contemporary approaches to the diagnosis and management of physical urticaria.
Lang DM, Hsieh FH, Bernstein JA
Ann Allergy Asthma Immunol 2013 Oct;111(4):235-41. Epub 2013 Aug 20 doi: 10.1016/j.anai.2013.07.031. PMID: 24054356
Physical urticaria. Its diagnosis and treatment.
Illig L
Curr Probl Dermatol 1973;5:79-116. PMID: 4150683

Recent clinical studies

Etiology

Prevalence, Management, and Anaphylaxis Risk of Cold Urticaria: A Systematic Review and Meta-Analysis.
Prosty C, Gabrielli S, Le M, Ensina LF, Zhang X, Netchiporouk E, Ben-Shoshan M
J Allergy Clin Immunol Pract 2022 Feb;10(2):586-596.e4. Epub 2021 Oct 18 doi: 10.1016/j.jaip.2021.10.012. PMID: 34673287
Vibrational angioedema: considerations for oral health care providers.
Aloyouny A, Stoopler ET
Spec Care Dentist 2016 Nov;36(6):335-338. Epub 2016 Apr 26 doi: 10.1111/scd.12185. PMID: 27114270
Unmet clinical needs in chronic spontaneous urticaria. A GA²LEN task force report.
Maurer M, Weller K, Bindslev-Jensen C, Giménez-Arnau A, Bousquet PJ, Bousquet J, Canonica GW, Church MK, Godse KV, Grattan CE, Greaves MW, Hide M, Kalogeromitros D, Kaplan AP, Saini SS, Zhu XJ, Zuberbier T
Allergy 2011 Mar;66(3):317-30. Epub 2010 Nov 17 doi: 10.1111/j.1398-9995.2010.02496.x. PMID: 21083565
Unusual urticarias.
Black AK
J Dermatol 2001 Nov;28(11):632-4. doi: 10.1111/j.1346-8138.2001.tb00050.x. PMID: 11770721
Cold-induced urticaria.
Mahmoudi M
J Am Osteopath Assoc 2001 May;101(5 Suppl):S1-4. PMID: 11409259

Diagnosis

Chronic Inducible Urticaria.
Ritzel D, Altrichter S
Immunol Allergy Clin North Am 2024 Aug;44(3):439-452. Epub 2024 May 18 doi: 10.1016/j.iac.2024.03.003. PMID: 38937008
Physical urticaria: Clinical features, pathogenesis, diagnostic work-up, and management.
McSweeney SM, Christou EAA, Maurer M, Grattan CE, Tziotzios C, McGrath JA
J Am Acad Dermatol 2023 Aug;89(2):324-337. Epub 2023 Mar 30 doi: 10.1016/j.jaad.2023.02.062. PMID: 37001733
Urticaria: A comprehensive review: Epidemiology, diagnosis, and work-up.
Antia C, Baquerizo K, Korman A, Bernstein JA, Alikhan A
J Am Acad Dermatol 2018 Oct;79(4):599-614. doi: 10.1016/j.jaad.2018.01.020. PMID: 30241623
Under pressure.
De Cunto A, Berti I, Minute M, Longo G
Eur J Pediatr 2013 Mar;172(3):417. Epub 2012 Sep 12 doi: 10.1007/s00431-012-1819-0. PMID: 22968937
Unmet clinical needs in chronic spontaneous urticaria. A GA²LEN task force report.
Maurer M, Weller K, Bindslev-Jensen C, Giménez-Arnau A, Bousquet PJ, Bousquet J, Canonica GW, Church MK, Godse KV, Grattan CE, Greaves MW, Hide M, Kalogeromitros D, Kaplan AP, Saini SS, Zhu XJ, Zuberbier T
Allergy 2011 Mar;66(3):317-30. Epub 2010 Nov 17 doi: 10.1111/j.1398-9995.2010.02496.x. PMID: 21083565

Therapy

Physical urticaria.
English J, Reddy K, Gonzalez-Estrada A, Bajaj K
BMJ Case Rep 2017 Apr 22;2017 doi: 10.1136/bcr-2017-220286. PMID: 28433981Free PMC Article
Under pressure.
De Cunto A, Berti I, Minute M, Longo G
Eur J Pediatr 2013 Mar;172(3):417. Epub 2012 Sep 12 doi: 10.1007/s00431-012-1819-0. PMID: 22968937
Physical urticaria.
Dice JP
Immunol Allergy Clin North Am 2004 May;24(2):225-46, vi. doi: 10.1016/j.iac.2004.01.005. PMID: 15120149
Unusual urticarias.
Black AK
J Dermatol 2001 Nov;28(11):632-4. doi: 10.1111/j.1346-8138.2001.tb00050.x. PMID: 11770721
Cold urticaria.
Lin RY, Janniger CK, Schwartz RA, Lambert WC
Am Fam Physician 1986 Feb;33(2):145-50. PMID: 2868642

Prognosis

Urticaria: A comprehensive review: Epidemiology, diagnosis, and work-up.
Antia C, Baquerizo K, Korman A, Bernstein JA, Alikhan A
J Am Acad Dermatol 2018 Oct;79(4):599-614. doi: 10.1016/j.jaad.2018.01.020. PMID: 30241623
Review of Physical Urticarias and Testing Methods.
Sánchez-Borges M, González-Aveledo L, Caballero-Fonseca F, Capriles-Hulett A
Curr Allergy Asthma Rep 2017 Aug;17(8):51. doi: 10.1007/s11882-017-0722-1. PMID: 28634900
Adrenergic urticaria: review of the literature and proposed mechanism.
Hogan SR, Mandrell J, Eilers D
J Am Acad Dermatol 2014 Apr;70(4):763-766. Epub 2013 Dec 25 doi: 10.1016/j.jaad.2013.10.062. PMID: 24373776
Solar urticaria successfully treated with intravenous immunoglobulins.
Maksimovic L, Frémont G, Jeanmougin M, Dubertret L, Viguier M
Dermatology 2009;218(3):252-4. Epub 2009 Jan 16 doi: 10.1159/000193998. PMID: 19147990
Unusual urticarias.
Black AK
J Dermatol 2001 Nov;28(11):632-4. doi: 10.1111/j.1346-8138.2001.tb00050.x. PMID: 11770721

Clinical prediction guides

Clinical and photobiological response in eight patients with solar urticaria under treatment with omalizumab, and review of the literature.
Morgado-Carrasco D, Fustà-Novell X, Podlipnik S, Combalia A, Aguilera P
Photodermatol Photoimmunol Photomed 2018 May;34(3):194-199. Epub 2018 Jan 4 doi: 10.1111/phpp.12370. PMID: 29171925
Dissociation between history and challenge in patients with physical urticaria.
Komarow HD, Arceo S, Young M, Nelson C, Metcalfe DD
J Allergy Clin Immunol Pract 2014 Nov-Dec;2(6):786-90. Epub 2014 Sep 8 doi: 10.1016/j.jaip.2014.07.008. PMID: 25439372Free PMC Article
Adrenergic urticaria: review of the literature and proposed mechanism.
Hogan SR, Mandrell J, Eilers D
J Am Acad Dermatol 2014 Apr;70(4):763-766. Epub 2013 Dec 25 doi: 10.1016/j.jaad.2013.10.062. PMID: 24373776
Solar urticaria successfully treated with intravenous immunoglobulins.
Maksimovic L, Frémont G, Jeanmougin M, Dubertret L, Viguier M
Dermatology 2009;218(3):252-4. Epub 2009 Jan 16 doi: 10.1159/000193998. PMID: 19147990
Antihistamines in urticaria.
Ring J, Brockow K, Ollert M, Engst R
Clin Exp Allergy 1999 Mar;29 Suppl 1:31-7. doi: 10.1046/j.1365-2222.1999.00006.x. PMID: 10209703

Recent systematic reviews

Prevalence, Management, and Anaphylaxis Risk of Cold Urticaria: A Systematic Review and Meta-Analysis.
Prosty C, Gabrielli S, Le M, Ensina LF, Zhang X, Netchiporouk E, Ben-Shoshan M
J Allergy Clin Immunol Pract 2022 Feb;10(2):586-596.e4. Epub 2021 Oct 18 doi: 10.1016/j.jaip.2021.10.012. PMID: 34673287
Omalizumab treatment in patients with chronic inducible urticaria: A systematic review of published evidence.
Maurer M, Metz M, Brehler R, Hillen U, Jakob T, Mahler V, Pföhler C, Staubach P, Treudler R, Wedi B, Magerl M
J Allergy Clin Immunol 2018 Feb;141(2):638-649. Epub 2017 Jul 24 doi: 10.1016/j.jaci.2017.06.032. PMID: 28751232
Diagnostic utility of challenge procedures for physical urticaria/angioedema syndromes: a systematic review.
Cuervo-Pardo L, Gonzalez-Estrada A, Lang DM
Curr Opin Allergy Clin Immunol 2016 Oct;16(5):511-5. doi: 10.1097/ACI.0000000000000298. PMID: 27585061
Aetiological factors associated with chronic urticaria in children: a systematic review.
Caffarelli C, Cuomo B, Cardinale F, Barberi S, Dascola CP, Agostinis F, Franceschini F, Bernardini R
Acta Derm Venereol 2013 May;93(3):268-72. doi: 10.2340/00015555-1511. PMID: 23224228
Efficacy and tolerability of second- and third-generation antihistamines in the treatment of acquired cold urticaria: a meta-analysis.
Weinstein ME, Wolff AH, Bielory L
Ann Allergy Asthma Immunol 2010 Jun;104(6):518-22. doi: 10.1016/j.anai.2010.04.002. PMID: 20568385

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