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Physical urticaria

MedGen UID:
1639813
•Concept ID:
C4551831
•
Disease or Syndrome
Synonym: physical urticaria
SNOMED CT: Physical urticaria (402601007)
 
HPO: HP:0410134
Monarch Initiative: MONDO:0006599

Definition

Urticaria caused by physical agents, such as heat, cold, light, friction. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPhysical urticaria

Professional guidelines

PubMed

Physical urticaria: Clinical features, pathogenesis, diagnostic work-up, and management.
McSweeney SM, Christou EAA, Maurer M, Grattan CE, Tziotzios C, McGrath JA
J Am Acad Dermatol 2023 Aug;89(2):324-337. Epub 2023 Mar 30 doi: 10.1016/j.jaad.2023.02.062. PMID: 37001733
Chronic Urticaria in Children: an Update on Diagnosis and Treatment.
Wang EA, Chan SK
Curr Allergy Asthma Rep 2020 Jun 6;20(8):31. doi: 10.1007/s11882-020-00929-1. PMID: 32506151
The definition, diagnostic testing, and management of chronic inducible urticarias - The EAACI/GA(2) LEN/EDF/UNEV consensus recommendations 2016 update and revision.
Magerl M, Altrichter S, Borzova E, Giménez-Arnau A, Grattan CE, Lawlor F, Mathelier-Fusade P, Meshkova RY, Zuberbier T, Metz M, Maurer M
Allergy 2016 Jun;71(6):780-802. Epub 2016 Apr 6 doi: 10.1111/all.12884. PMID: 26991006

Recent clinical studies

Etiology

Chronic Urticaria in Children: an Update on Diagnosis and Treatment.
Wang EA, Chan SK
Curr Allergy Asthma Rep 2020 Jun 6;20(8):31. doi: 10.1007/s11882-020-00929-1. PMID: 32506151
Adrenergic urticaria: review of the literature and proposed mechanism.
Hogan SR, Mandrell J, Eilers D
J Am Acad Dermatol 2014 Apr;70(4):763-766. Epub 2013 Dec 25 doi: 10.1016/j.jaad.2013.10.062. PMID: 24373776
Unmet clinical needs in chronic spontaneous urticaria. A GA²LEN task force report.
Maurer M, Weller K, Bindslev-Jensen C, Giménez-Arnau A, Bousquet PJ, Bousquet J, Canonica GW, Church MK, Godse KV, Grattan CE, Greaves MW, Hide M, Kalogeromitros D, Kaplan AP, Saini SS, Zhu XJ, Zuberbier T
Allergy 2011 Mar;66(3):317-30. Epub 2010 Nov 17 doi: 10.1111/j.1398-9995.2010.02496.x. PMID: 21083565
Unusual urticarias.
Black AK
J Dermatol 2001 Nov;28(11):632-4. doi: 10.1111/j.1346-8138.2001.tb00050.x. PMID: 11770721
Cold-induced urticaria.
Mahmoudi M
J Am Osteopath Assoc 2001 May;101(5 Suppl):S1-4. PMID: 11409259

Diagnosis

Physical urticaria: Clinical features, pathogenesis, diagnostic work-up, and management.
McSweeney SM, Christou EAA, Maurer M, Grattan CE, Tziotzios C, McGrath JA
J Am Acad Dermatol 2023 Aug;89(2):324-337. Epub 2023 Mar 30 doi: 10.1016/j.jaad.2023.02.062. PMID: 37001733
Urticaria: A comprehensive review: Epidemiology, diagnosis, and work-up.
Antia C, Baquerizo K, Korman A, Bernstein JA, Alikhan A
J Am Acad Dermatol 2018 Oct;79(4):599-614. doi: 10.1016/j.jaad.2018.01.020. PMID: 30241623
Physical urticarias and cholinergic urticaria.
Abajian M, Schoepke N, Altrichter S, Zuberbier T, Maurer M
Immunol Allergy Clin North Am 2014 Feb;34(1):73-88. Epub 2013 Oct 28 doi: 10.1016/j.iac.2013.09.010. PMID: 24262690
Physical urticaria.
Abajian M, Młynek A, Maurer M
Curr Allergy Asthma Rep 2012 Aug;12(4):281-7. doi: 10.1007/s11882-012-0269-0. PMID: 22653630
Unmet clinical needs in chronic spontaneous urticaria. A GA²LEN task force report.
Maurer M, Weller K, Bindslev-Jensen C, Giménez-Arnau A, Bousquet PJ, Bousquet J, Canonica GW, Church MK, Godse KV, Grattan CE, Greaves MW, Hide M, Kalogeromitros D, Kaplan AP, Saini SS, Zhu XJ, Zuberbier T
Allergy 2011 Mar;66(3):317-30. Epub 2010 Nov 17 doi: 10.1111/j.1398-9995.2010.02496.x. PMID: 21083565

Therapy

Physical urticaria.
English J, Reddy K, Gonzalez-Estrada A, Bajaj K
BMJ Case Rep 2017 Apr 22;2017 doi: 10.1136/bcr-2017-220286. PMID: 28433981Free PMC Article
Therapy of antihistamine-resistant chronic spontaneous urticaria.
Greiwe J, Bernstein JA
Expert Rev Clin Immunol 2017 Apr;13(4):311-318. Epub 2016 Nov 3 doi: 10.1080/1744666X.2017.1249467. PMID: 27744711
Physical urticaria.
Dice JP
Immunol Allergy Clin North Am 2004 May;24(2):225-46, vi. doi: 10.1016/j.iac.2004.01.005. PMID: 15120149
Unusual urticarias.
Black AK
J Dermatol 2001 Nov;28(11):632-4. doi: 10.1111/j.1346-8138.2001.tb00050.x. PMID: 11770721
Delayed pressure urticaria.
Kobza-Black A
J Investig Dermatol Symp Proc 2001 Nov;6(2):148-9. doi: 10.1046/j.0022-202x.2001.00030.x. PMID: 11764304

Prognosis

Urticaria: A comprehensive review: Epidemiology, diagnosis, and work-up.
Antia C, Baquerizo K, Korman A, Bernstein JA, Alikhan A
J Am Acad Dermatol 2018 Oct;79(4):599-614. doi: 10.1016/j.jaad.2018.01.020. PMID: 30241623
Review of Physical Urticarias and Testing Methods.
Sánchez-Borges M, González-Aveledo L, Caballero-Fonseca F, Capriles-Hulett A
Curr Allergy Asthma Rep 2017 Aug;17(8):51. doi: 10.1007/s11882-017-0722-1. PMID: 28634900
Diagnostic utility of challenge procedures for physical urticaria/angioedema syndromes: a systematic review.
Cuervo-Pardo L, Gonzalez-Estrada A, Lang DM
Curr Opin Allergy Clin Immunol 2016 Oct;16(5):511-5. doi: 10.1097/ACI.0000000000000298. PMID: 27585061
Adrenergic urticaria: review of the literature and proposed mechanism.
Hogan SR, Mandrell J, Eilers D
J Am Acad Dermatol 2014 Apr;70(4):763-766. Epub 2013 Dec 25 doi: 10.1016/j.jaad.2013.10.062. PMID: 24373776
Unusual urticarias.
Black AK
J Dermatol 2001 Nov;28(11):632-4. doi: 10.1111/j.1346-8138.2001.tb00050.x. PMID: 11770721

Clinical prediction guides

Clinical and photobiological response in eight patients with solar urticaria under treatment with omalizumab, and review of the literature.
Morgado-Carrasco D, Fustà-Novell X, Podlipnik S, Combalia A, Aguilera P
Photodermatol Photoimmunol Photomed 2018 May;34(3):194-199. Epub 2018 Jan 4 doi: 10.1111/phpp.12370. PMID: 29171925
Diagnostic utility of challenge procedures for physical urticaria/angioedema syndromes: a systematic review.
Cuervo-Pardo L, Gonzalez-Estrada A, Lang DM
Curr Opin Allergy Clin Immunol 2016 Oct;16(5):511-5. doi: 10.1097/ACI.0000000000000298. PMID: 27585061
Adrenergic urticaria: review of the literature and proposed mechanism.
Hogan SR, Mandrell J, Eilers D
J Am Acad Dermatol 2014 Apr;70(4):763-766. Epub 2013 Dec 25 doi: 10.1016/j.jaad.2013.10.062. PMID: 24373776
Antihistamines in urticaria.
Ring J, Brockow K, Ollert M, Engst R
Clin Exp Allergy 1999 Mar;29 Suppl 1:31-7. doi: 10.1046/j.1365-2222.1999.00006.x. PMID: 10209703
Physical urticaria/angioedema: an experimental model of mast cell activation in humans.
Soter NA, Wasserman SI
J Allergy Clin Immunol 1980 Nov;66(5):358-65. doi: 10.1016/0091-6749(80)90114-1. PMID: 7002977

Recent systematic reviews

Prevalence, Management, and Anaphylaxis Risk of Cold Urticaria: A Systematic Review and Meta-Analysis.
Prosty C, Gabrielli S, Le M, Ensina LF, Zhang X, Netchiporouk E, Ben-Shoshan M
J Allergy Clin Immunol Pract 2022 Feb;10(2):586-596.e4. Epub 2021 Oct 18 doi: 10.1016/j.jaip.2021.10.012. PMID: 34673287
Omalizumab treatment in patients with chronic inducible urticaria: A systematic review of published evidence.
Maurer M, Metz M, Brehler R, Hillen U, Jakob T, Mahler V, Pföhler C, Staubach P, Treudler R, Wedi B, Magerl M
J Allergy Clin Immunol 2018 Feb;141(2):638-649. Epub 2017 Jul 24 doi: 10.1016/j.jaci.2017.06.032. PMID: 28751232
Diagnostic utility of challenge procedures for physical urticaria/angioedema syndromes: a systematic review.
Cuervo-Pardo L, Gonzalez-Estrada A, Lang DM
Curr Opin Allergy Clin Immunol 2016 Oct;16(5):511-5. doi: 10.1097/ACI.0000000000000298. PMID: 27585061
Aetiological factors associated with chronic urticaria in children: a systematic review.
Caffarelli C, Cuomo B, Cardinale F, Barberi S, Dascola CP, Agostinis F, Franceschini F, Bernardini R
Acta Derm Venereol 2013 May;93(3):268-72. doi: 10.2340/00015555-1511. PMID: 23224228
Efficacy and tolerability of second- and third-generation antihistamines in the treatment of acquired cold urticaria: a meta-analysis.
Weinstein ME, Wolff AH, Bielory L
Ann Allergy Asthma Immunol 2010 Jun;104(6):518-22. doi: 10.1016/j.anai.2010.04.002. PMID: 20568385

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