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Metastatic Colon Carcinoma

MedGen UID:
1649079
•Concept ID:
C4744565
•
Neoplastic Process

Definition

A carcinoma that arises from the colon and has metastasized to another anatomic site. [from NCI]

Professional guidelines

PubMed

The hemodynamic effects of treatment with interleukin-2 and lymphokine-activated killer cells.
Gaynor ER, Vitek L, Sticklin L, Creekmore SP, Ferraro ME, Thomas JX Jr, Fisher SG, Fisher RI
Ann Intern Med 1988 Dec 15;109(12):953-8. doi: 10.7326/0003-4819-109-12-953. PMID: 3264128
Intra-arterial chemotherapy using an implantable infusion pump and liver irradiation for the treatment of hepatic metastases.
Barone RM, Byfield JE, Goldfarb PB, Frankel S, Ginn C, Greer S
Cancer 1982 Sep 1;50(5):850-62. doi: 10.1002/1097-0142(19820901)50:5<850::aid-cncr2820500508>3.0.co;2-2. PMID: 6212114
Scintigraphic criteria for hepatic metastases from cancer of the colon and breast.
Drum DE, Beard JM
J Nucl Med 1976 Aug;17(8):677-80. PMID: 932808

Recent clinical studies

Etiology

Treatment interval in curative treatment of colon cancer, does it impact (cancer free) survival? A non-inferiority analysis.
Strous MTA, Molenaar CJL, Franssen RFW, van Osch F, Belgers E, Bloemen JG, Slooter GD, Melenhorst J, Heemskerk J, de Bruïne AP, Janssen-Heijnen MLG, Vogelaar FJ
Br J Cancer 2024 Feb;130(2):251-259. Epub 2023 Dec 12 doi: 10.1038/s41416-023-02505-6. PMID: 38087040Free PMC Article
Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents.
Romagnoli R, Preti D, Hamel E, Bortolozzi R, Viola G, Brancale A, Ferla S, Morciano G, Pinton P
Bioorg Chem 2021 Jul;112:104919. Epub 2021 Apr 20 doi: 10.1016/j.bioorg.2021.104919. PMID: 33957538
Sixth nerve palsy as the presenting symptom of metastatic colon carcinoma.
Kinori M, Ben Bassat I, Huna-Baron R
Int Ophthalmol 2011 Feb;31(1):69-72. Epub 2010 Oct 13 doi: 10.1007/s10792-010-9408-6. PMID: 20941638
Obstructed small bowel ruptured toward the inguinal canal resulting from metastatic colon carcinoma in an irreducible, recurrent inguinal hernia with mesh-plug repair: Report of a case.
Li S, Li Y, Tang L, Zhao P
Eur J Surg Oncol 2010 Oct;36(10):1012-4. Epub 2010 Feb 6 doi: 10.1016/j.ejso.2010.01.008. PMID: 20138732
Bile duct strictures associated with hepatic arterial infusion chemotherapy.
Clark RA, Gallant TE
Gastrointest Radiol 1987;12(2):148-51. doi: 10.1007/BF01885126. PMID: 2951292

Diagnosis

Metastatic colon carcinoma to the prostate gland.
Kang A, Lee JH, Lin E, Westerhoff M
J Comput Assist Tomogr 2013 May-Jun;37(3):463-5. doi: 10.1097/RCT.0b013e3182898248. PMID: 23674022
Sixth nerve palsy as the presenting symptom of metastatic colon carcinoma.
Kinori M, Ben Bassat I, Huna-Baron R
Int Ophthalmol 2011 Feb;31(1):69-72. Epub 2010 Oct 13 doi: 10.1007/s10792-010-9408-6. PMID: 20941638
Sister Mary Joseph's nodule as a diagnostic clue to metastatic colon carcinoma.
Shen Z, Yang X, Chen L, Hao F, Zhong B
J Clin Oncol 2009 Jul 1;27(19):e1-2. Epub 2009 May 11 doi: 10.1200/JCO.2009.22.1515. PMID: 19433679
Intracranial meningioma containing metastatic colon carcinoma.
Benedetto N, Perrini P, Scollato A, Buccoliero AM, Di Lorenzo N
Acta Neurochir (Wien) 2007 Aug;149(8):799-803; discussion 803. Epub 2007 Aug 1 doi: 10.1007/s00701-007-1239-5. PMID: 17660939
Two schedules of second-line irinotecan for metastatic colon carcinoma.
Earle CC, Kwok A, Gazelle GS, Fuchs CS
Cancer 2004 Dec 1;101(11):2533-9. doi: 10.1002/cncr.20691. PMID: 15503310

Therapy

Cetuximab-related tumor lysis syndrome in metastatic colon carcinoma.
Krishnan G, D'Silva K, Al-Janadi A
J Clin Oncol 2008 May 10;26(14):2406-8. doi: 10.1200/JCO.2007.14.7603. PMID: 18467734
Two schedules of second-line irinotecan for metastatic colon carcinoma.
Earle CC, Kwok A, Gazelle GS, Fuchs CS
Cancer 2004 Dec 1;101(11):2533-9. doi: 10.1002/cncr.20691. PMID: 15503310
Phase I study of direct administration of a replication deficient adenovirus vector containing the E. coli cytosine deaminase gene to metastatic colon carcinoma of the liver in association with the oral administration of the pro-drug 5-fluorocytosine.
Crystal RG, Hirschowitz E, Lieberman M, Daly J, Kazam E, Henschke C, Yankelevitz D, Kemeny N, Silverstein R, Ohwada A, Russi T, Mastrangeli A, Sanders A, Cooke J, Harvey BG
Hum Gene Ther 1997 May 20;8(8):985-1001. doi: 10.1089/hum.1997.8.8-985. PMID: 9195221
Pilot radioimmunotherapy trial with 131I-labeled murine monoclonal antibody CC49 and deoxyspergualin in metastatic colon carcinoma.
Divgi CR, Scott AM, Gulec S, Broussard EK, Levy N, Young C, Capitelli P, Daghighian F, Williams JM, Finn RD
Clin Cancer Res 1995 Dec;1(12):1503-10. PMID: 9815950
Interleukin-7 gene transfer in patients with metastatic colon carcinoma, renal cell carcinoma, melanoma, or with lymphoma.
Schmidt-Wolf IG, Huhn D, Neubauer A, Wittig B
Hum Gene Ther 1994 Sep;5(9):1161-8. doi: 10.1089/hum.1994.5.9-1161. PMID: 7530496

Prognosis

Chemotherapy in patient with colon cancer after renal transplantation: A case report with literature review.
Fang W
Medicine (Baltimore) 2018 Feb;97(5):e9678. doi: 10.1097/MD.0000000000009678. PMID: 29384845Free PMC Article
Obstructed small bowel ruptured toward the inguinal canal resulting from metastatic colon carcinoma in an irreducible, recurrent inguinal hernia with mesh-plug repair: Report of a case.
Li S, Li Y, Tang L, Zhao P
Eur J Surg Oncol 2010 Oct;36(10):1012-4. Epub 2010 Feb 6 doi: 10.1016/j.ejso.2010.01.008. PMID: 20138732
Fatal brain swelling due to superior vena cava syndrome.
Rabinstein AA, Wijdicks EF
Neurocrit Care 2009;10(1):91-2. Epub 2008 Aug 14 doi: 10.1007/s12028-008-9129-0. PMID: 18704767
Pilot radioimmunotherapy trial with 131I-labeled murine monoclonal antibody CC49 and deoxyspergualin in metastatic colon carcinoma.
Divgi CR, Scott AM, Gulec S, Broussard EK, Levy N, Young C, Capitelli P, Daghighian F, Williams JM, Finn RD
Clin Cancer Res 1995 Dec;1(12):1503-10. PMID: 9815950
Liver resection for metastatic colon carcinoma.
Bengmark S
HPB Surg 1989 Apr;1(2):165-7. doi: 10.1155/1989/40169. PMID: 2487064Free PMC Article

Clinical prediction guides

Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents.
Romagnoli R, Preti D, Hamel E, Bortolozzi R, Viola G, Brancale A, Ferla S, Morciano G, Pinton P
Bioorg Chem 2021 Jul;112:104919. Epub 2021 Apr 20 doi: 10.1016/j.bioorg.2021.104919. PMID: 33957538
Chemotherapy in patient with colon cancer after renal transplantation: A case report with literature review.
Fang W
Medicine (Baltimore) 2018 Feb;97(5):e9678. doi: 10.1097/MD.0000000000009678. PMID: 29384845Free PMC Article
Identification, characterization and utilization of tumor cell selectin ligands in the design of colon cancer diagnostics.
Thomas SN, Tong Z, Stebe KJ, Konstantopoulos K
Biorheology 2009;46(3):207-25. doi: 10.3233/BIR-2009-0534. PMID: 19581728
Differential role of Fas/Fas ligand interactions in cytolysis of primary and metastatic colon carcinoma cell lines by human antigen-specific CD8+ CTL.
Bergmann-Leitner ES, Abrams SI
J Immunol 2000 May 1;164(9):4941-54. doi: 10.4049/jimmunol.164.9.4941. PMID: 10779805
Phase II trial of high-dose melphalan and autologous bone marrow transplantation for metastatic colon carcinoma.
Leff RS, Thompson JM, Johnson DB, Mosley KR, Daly MB, Knight WA 3rd, Ruxer RL Jr, Messerschmidt GL
J Clin Oncol 1986 Nov;4(11):1586-91. doi: 10.1200/JCO.1986.4.11.1586. PMID: 3534154

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