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Hobnail Variant Thyroid Gland Papillary Carcinoma

MedGen UID:
1649190
Concept ID:
C4744535
Neoplastic Process

Definition

A rare variant of papillary thyroid gland carcinoma in which more than 30% of cells have hobnail features. (WHO) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHobnail Variant Thyroid Gland Papillary Carcinoma

Professional guidelines

PubMed

Poma AM, Macerola E, Proietti A, Vignali P, Sparavelli R, Torregrossa L, Matrone A, Basolo A, Elisei R, Santini F, Ugolini C
Front Endocrinol (Lausanne) 2022;13:842424. Epub 2022 Mar 2 doi: 10.3389/fendo.2022.842424. PMID: 35311230Free PMC Article
Coca-Pelaz A, Shah JP, Hernandez-Prera JC, Ghossein RA, Rodrigo JP, Hartl DM, Olsen KD, Shaha AR, Zafereo M, Suarez C, Nixon IJ, Randolph GW, Mäkitie AA, Kowalski LP, Vander Poorten V, Sanabria A, Guntinas-Lichius O, Simo R, Zbären P, Angelos P, Khafif A, Rinaldo A, Ferlito A
Adv Ther 2020 Jul;37(7):3112-3128. Epub 2020 Jun 1 doi: 10.1007/s12325-020-01391-1. PMID: 32488657Free PMC Article
Asioli S, Erickson LA, Righi A, Lloyd RV
Hum Pathol 2013 Mar;44(3):320-8. Epub 2012 Oct 1 doi: 10.1016/j.humpath.2012.06.003. PMID: 23036367

Recent clinical studies

Etiology

Poma AM, Macerola E, Proietti A, Vignali P, Sparavelli R, Torregrossa L, Matrone A, Basolo A, Elisei R, Santini F, Ugolini C
Front Endocrinol (Lausanne) 2022;13:842424. Epub 2022 Mar 2 doi: 10.3389/fendo.2022.842424. PMID: 35311230Free PMC Article
De Graef A, Van Den Heede K, Meert V, Van Slycke S
Acta Chir Belg 2021 Apr;121(2):77-85. Epub 2021 Feb 12 doi: 10.1080/00015458.2021.1881338. PMID: 33550925
Donaldson LB, Yan F, Morgan PF, Kaczmar JM, Fernandes JK, Nguyen SA, Jester RL, Day TA
Endocrine 2021 Apr;72(1):27-39. Epub 2020 Oct 6 doi: 10.1007/s12020-020-02505-z. PMID: 33025563Free PMC Article
Cipriani NA
Surg Pathol Clin 2019 Dec;12(4):883-900. Epub 2019 Sep 18 doi: 10.1016/j.path.2019.07.001. PMID: 31672296
Morandi L, Righi A, Maletta F, Rucci P, Pagni F, Gallo M, Rossi S, Caporali L, Sapino A, Lloyd RV, Asioli S
Endocr Relat Cancer 2017 Feb;24(2):107-117. Epub 2017 Jan 6 doi: 10.1530/ERC-16-0546. PMID: 28062544

Diagnosis

Galuppini F, Censi S, Merante Boschin I, Fassan M, Sbaraglia M, Valeri N, Hahne JC, Bertazza L, Munari G, Galasso M, Cascione L, Barollo S, Rugge M, Vianello F, Dei Tos AP, Mian C, Pennelli G
Front Endocrinol (Lausanne) 2022;13:834075. Epub 2022 Feb 23 doi: 10.3389/fendo.2022.834075. PMID: 35282462Free PMC Article
De Graef A, Van Den Heede K, Meert V, Van Slycke S
Acta Chir Belg 2021 Apr;121(2):77-85. Epub 2021 Feb 12 doi: 10.1080/00015458.2021.1881338. PMID: 33550925
Donaldson LB, Yan F, Morgan PF, Kaczmar JM, Fernandes JK, Nguyen SA, Jester RL, Day TA
Endocrine 2021 Apr;72(1):27-39. Epub 2020 Oct 6 doi: 10.1007/s12020-020-02505-z. PMID: 33025563Free PMC Article
Coca-Pelaz A, Shah JP, Hernandez-Prera JC, Ghossein RA, Rodrigo JP, Hartl DM, Olsen KD, Shaha AR, Zafereo M, Suarez C, Nixon IJ, Randolph GW, Mäkitie AA, Kowalski LP, Vander Poorten V, Sanabria A, Guntinas-Lichius O, Simo R, Zbären P, Angelos P, Khafif A, Rinaldo A, Ferlito A
Adv Ther 2020 Jul;37(7):3112-3128. Epub 2020 Jun 1 doi: 10.1007/s12325-020-01391-1. PMID: 32488657Free PMC Article
Sak SD
Turk Patoloji Derg 2015;31 Suppl 1:34-47. doi: 10.5146/tjpath.2015.01313. PMID: 26177316

Therapy

Ito Y, Hirokawa M, Hayashi T, Ota H, Oshita M, Kihara M, Miya A, Miyauchi A
Endocr J 2020 Oct 28;67(10):1047-1053. Epub 2020 Jun 18 doi: 10.1507/endocrj.EJ20-0248. PMID: 32554948

Prognosis

De Graef A, Van Den Heede K, Meert V, Van Slycke S
Acta Chir Belg 2021 Apr;121(2):77-85. Epub 2021 Feb 12 doi: 10.1080/00015458.2021.1881338. PMID: 33550925
Coca-Pelaz A, Shah JP, Hernandez-Prera JC, Ghossein RA, Rodrigo JP, Hartl DM, Olsen KD, Shaha AR, Zafereo M, Suarez C, Nixon IJ, Randolph GW, Mäkitie AA, Kowalski LP, Vander Poorten V, Sanabria A, Guntinas-Lichius O, Simo R, Zbären P, Angelos P, Khafif A, Rinaldo A, Ferlito A
Adv Ther 2020 Jul;37(7):3112-3128. Epub 2020 Jun 1 doi: 10.1007/s12325-020-01391-1. PMID: 32488657Free PMC Article
Cipriani NA
Surg Pathol Clin 2019 Dec;12(4):883-900. Epub 2019 Sep 18 doi: 10.1016/j.path.2019.07.001. PMID: 31672296
Ambrosi F, Righi A, Ricci C, Erickson LA, Lloyd RV, Asioli S
Endocr Pathol 2017 Dec;28(4):293-301. doi: 10.1007/s12022-017-9502-7. PMID: 29019044
Ieni A, Barresi V, Cardia R, Licata L, Di Bari F, Benvenga S, Tuccari G
Rev Endocr Metab Disord 2016 Dec;17(4):521-527. doi: 10.1007/s11154-016-9398-4. PMID: 27896649

Clinical prediction guides

Poma AM, Macerola E, Proietti A, Vignali P, Sparavelli R, Torregrossa L, Matrone A, Basolo A, Elisei R, Santini F, Ugolini C
Front Endocrinol (Lausanne) 2022;13:842424. Epub 2022 Mar 2 doi: 10.3389/fendo.2022.842424. PMID: 35311230Free PMC Article
Cipriani NA
Surg Pathol Clin 2019 Dec;12(4):883-900. Epub 2019 Sep 18 doi: 10.1016/j.path.2019.07.001. PMID: 31672296
Sak SD
Turk Patoloji Derg 2015;31 Suppl 1:34-47. doi: 10.5146/tjpath.2015.01313. PMID: 26177316
Lubitz CC, Economopoulos KP, Pawlak AC, Lynch K, Dias-Santagata D, Faquin WC, Sadow PM
Thyroid 2014 Jun;24(6):958-65. Epub 2014 Mar 6 doi: 10.1089/thy.2013.0573. PMID: 24417340Free PMC Article
Asioli S, Erickson LA, Righi A, Lloyd RV
Hum Pathol 2013 Mar;44(3):320-8. Epub 2012 Oct 1 doi: 10.1016/j.humpath.2012.06.003. PMID: 23036367

Recent systematic reviews

Donaldson LB, Yan F, Morgan PF, Kaczmar JM, Fernandes JK, Nguyen SA, Jester RL, Day TA
Endocrine 2021 Apr;72(1):27-39. Epub 2020 Oct 6 doi: 10.1007/s12020-020-02505-z. PMID: 33025563Free PMC Article
Lee YS, Kim Y, Jeon S, Bae JS, Jung SL, Jung CK
Int J Clin Exp Pathol 2015;8(7):7988-97. Epub 2015 Jul 1 PMID: 26339365Free PMC Article

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