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Prostate Adenocarcinoma without Neuroendocrine Differentiation

MedGen UID:
1664151
Concept ID:
C4725830
Neoplastic Process
Synonym: Prostate Adenocarcinoma without Evidence of Neuroendocrine Differentiation

Definition

A prostate adenocarcinoma characterized by the absence of focal or diffuse neuroendocrine differentiation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProstate Adenocarcinoma without Neuroendocrine Differentiation

Professional guidelines

PubMed

de Kouchkovsky I, Chan E, Schloss C, Poehlein C, Aggarwal R
Prostate 2024 Apr;84(5):426-440. Epub 2024 Jan 3 doi: 10.1002/pros.24664. PMID: 38173302
Akamatsu S, Inoue T, Ogawa O, Gleave ME
Int J Urol 2018 Apr;25(4):345-351. Epub 2018 Feb 3 doi: 10.1111/iju.13526. PMID: 29396873
Fine SW
Adv Anat Pathol 2012 Jul;19(4):204-16. doi: 10.1097/PAP.0b013e31825c6b92. PMID: 22692283

Recent clinical studies

Etiology

de Kouchkovsky I, Chan E, Schloss C, Poehlein C, Aggarwal R
Prostate 2024 Apr;84(5):426-440. Epub 2024 Jan 3 doi: 10.1002/pros.24664. PMID: 38173302
Ji Y, Zhang W, Shen K, Su R, Liu X, Ma Z, Liu B, Hu C, Xue Y, Xin Z, Yang Y, Li A, Jiang Z, Jing N, Zhu HH, Dong L, Zhu Y, Dong B, Pan J, Wang Q, Xue W
Nat Commun 2023 Nov 28;14(1):7794. doi: 10.1038/s41467-023-43676-3. PMID: 38016952Free PMC Article
Chen CC, Tran W, Song K, Sugimoto T, Obusan MB, Wang L, Sheu KM, Cheng D, Ta L, Varuzhanyan G, Huang A, Xu R, Zeng Y, Borujerdpur A, Bayley NA, Noguchi M, Mao Z, Morrissey C, Corey E, Nelson PS, Zhao Y, Huang J, Park JW, Witte ON, Graeber TG
Cancer Cell 2023 Dec 11;41(12):2066-2082.e9. Epub 2023 Nov 22 doi: 10.1016/j.ccell.2023.10.009. PMID: 37995683Free PMC Article
Volante M, Grillo F, Massa F, Maletta F, Mastracci L, Campora M, Ferro J, Vanoli A, Papotti M
Pathologica 2021 Feb;113(1):19-27. doi: 10.32074/1591-951X-230. PMID: 33686307Free PMC Article
Aggarwal R, Huang J, Alumkal JJ, Zhang L, Feng FY, Thomas GV, Weinstein AS, Friedl V, Zhang C, Witte ON, Lloyd P, Gleave M, Evans CP, Youngren J, Beer TM, Rettig M, Wong CK, True L, Foye A, Playdle D, Ryan CJ, Lara P, Chi KN, Uzunangelov V, Sokolov A, Newton Y, Beltran H, Demichelis F, Rubin MA, Stuart JM, Small EJ
J Clin Oncol 2018 Aug 20;36(24):2492-2503. Epub 2018 Jul 9 doi: 10.1200/JCO.2017.77.6880. PMID: 29985747Free PMC Article

Diagnosis

Liu S, Chai T, Garcia-Marques F, Yin Q, Hsu EC, Shen M, Shaw Toland AM, Bermudez A, Hartono AB, Massey CF, Lee CS, Zheng L, Baron M, Denning CJ, Aslan M, Nguyen HM, Nolley R, Zoubeidi A, Das M, Kunder CA, Howitt BE, Soh HT, Weissman IL, Liss MA, Chin AI, Brooks JD, Corey E, Pitteri SJ, Huang J, Stoyanova T
Cell Rep Med 2024 Feb 20;5(2):101381. Epub 2024 Jan 19 doi: 10.1016/j.xcrm.2023.101381. PMID: 38244540Free PMC Article
de Kouchkovsky I, Chan E, Schloss C, Poehlein C, Aggarwal R
Prostate 2024 Apr;84(5):426-440. Epub 2024 Jan 3 doi: 10.1002/pros.24664. PMID: 38173302
Volante M, Grillo F, Massa F, Maletta F, Mastracci L, Campora M, Ferro J, Vanoli A, Papotti M
Pathologica 2021 Feb;113(1):19-27. doi: 10.32074/1591-951X-230. PMID: 33686307Free PMC Article
Langbein T, Weber WA, Eiber M
J Nucl Med 2019 Sep;60(Suppl 2):13S-19S. doi: 10.2967/jnumed.118.220566. PMID: 31481583
Puca L, Vlachostergios PJ, Beltran H
Cold Spring Harb Perspect Med 2019 Feb 1;9(2) doi: 10.1101/cshperspect.a030593. PMID: 29844220Free PMC Article

Therapy

de Kouchkovsky I, Chan E, Schloss C, Poehlein C, Aggarwal R
Prostate 2024 Apr;84(5):426-440. Epub 2024 Jan 3 doi: 10.1002/pros.24664. PMID: 38173302
Jing N, Zhang K, Chen X, Liu K, Wang J, Xiao L, Zhang W, Ma P, Xu P, Cheng C, Wang D, Zhao H, He Y, Ji Z, Xin Z, Sun Y, Zhang Y, Bao W, Gong Y, Fan L, Ji Y, Zhuang G, Wang Q, Dong B, Zhang P, Xue W, Gao WQ, Zhu HH
J Clin Invest 2023 Dec 15;133(24) doi: 10.1172/JCI168670. PMID: 38099497Free PMC Article
Han M, Li F, Zhang Y, Dai P, He J, Li Y, Zhu Y, Zheng J, Huang H, Bai F, Gao D
Cancer Cell 2022 Nov 14;40(11):1306-1323.e8. Epub 2022 Nov 3 doi: 10.1016/j.ccell.2022.10.011. PMID: 36332622
Cheng Q, Butler W, Zhou Y, Zhang H, Tang L, Perkinson K, Chen X, Jiang XS, McCall SJ, Inman BA, Huang J
Eur Urol 2022 May;81(5):446-455. Epub 2022 Jan 17 doi: 10.1016/j.eururo.2021.12.039. PMID: 35058087Free PMC Article
Balakrishna P, George S, Hatoum H, Mukherjee S
Int J Mol Sci 2021 Jan 28;22(3) doi: 10.3390/ijms22031268. PMID: 33525332Free PMC Article

Prognosis

de Kouchkovsky I, Chan E, Schloss C, Poehlein C, Aggarwal R
Prostate 2024 Apr;84(5):426-440. Epub 2024 Jan 3 doi: 10.1002/pros.24664. PMID: 38173302
Chen CC, Tran W, Song K, Sugimoto T, Obusan MB, Wang L, Sheu KM, Cheng D, Ta L, Varuzhanyan G, Huang A, Xu R, Zeng Y, Borujerdpur A, Bayley NA, Noguchi M, Mao Z, Morrissey C, Corey E, Nelson PS, Zhao Y, Huang J, Park JW, Witte ON, Graeber TG
Cancer Cell 2023 Dec 11;41(12):2066-2082.e9. Epub 2023 Nov 22 doi: 10.1016/j.ccell.2023.10.009. PMID: 37995683Free PMC Article
Cheng Q, Butler W, Zhou Y, Zhang H, Tang L, Perkinson K, Chen X, Jiang XS, McCall SJ, Inman BA, Huang J
Eur Urol 2022 May;81(5):446-455. Epub 2022 Jan 17 doi: 10.1016/j.eururo.2021.12.039. PMID: 35058087Free PMC Article
Volante M, Grillo F, Massa F, Maletta F, Mastracci L, Campora M, Ferro J, Vanoli A, Papotti M
Pathologica 2021 Feb;113(1):19-27. doi: 10.32074/1591-951X-230. PMID: 33686307Free PMC Article
Park JW, Lee JK, Sheu KM, Wang L, Balanis NG, Nguyen K, Smith BA, Cheng C, Tsai BL, Cheng D, Huang J, Kurdistani SK, Graeber TG, Witte ON
Science 2018 Oct 5;362(6410):91-95. doi: 10.1126/science.aat5749. PMID: 30287662Free PMC Article

Clinical prediction guides

Zhao SG, Sperger JM, Schehr JL, McKay RR, Emamekhoo H, Singh A, Schultz ZD, Bade RM, Stahlfeld CN, Gilsdorf CS, Hernandez CI, Wolfe SK, Mayberry RD, Krause HM, Bootsma M, Helzer KT, Rydzewski N, Bakhtiar H, Shi Y, Blitzer G, Kyriakopoulos CE, Kosoff D, Wei XX, Floberg J, Sethakorn N, Sharifi M, Harari PM, Huang W, Beltran H, Choueiri TK, Scher HI, Rathkopf DE, Halabi S, Armstrong AJ, Beebe DJ, Yu M, Sundling KE, Taplin ME, Lang JM
J Clin Invest 2022 Nov 1;132(21) doi: 10.1172/JCI161858. PMID: 36317634Free PMC Article
Kaur H, Samarska I, Lu J, Faisal F, Maughan BL, Murali S, Asrani K, Alshalalfa M, Antonarakis ES, Epstein JI, Joshu CE, Schaeffer EM, Mosquera JM, Lotan TL
Prostate 2020 Sep;80(12):1012-1023. Epub 2020 Jul 10 doi: 10.1002/pros.24035. PMID: 32649013Free PMC Article
Yasumizu Y, Rajabi H, Jin C, Hata T, Pitroda S, Long MD, Hagiwara M, Li W, Hu Q, Liu S, Yamashita N, Fushimi A, Kui L, Samur M, Yamamoto M, Zhang Y, Zhang N, Hong D, Maeda T, Kosaka T, Wong KK, Oya M, Kufe D
Nat Commun 2020 Jan 17;11(1):338. doi: 10.1038/s41467-019-14219-6. PMID: 31953400Free PMC Article
Miettinen M, McCue PA, Sarlomo-Rikala M, Rys J, Czapiewski P, Wazny K, Langfort R, Waloszczyk P, Biernat W, Lasota J, Wang Z
Am J Surg Pathol 2014 Jan;38(1):13-22. doi: 10.1097/PAS.0b013e3182a0218f. PMID: 24145643Free PMC Article
Fine SW
Adv Anat Pathol 2012 Jul;19(4):204-16. doi: 10.1097/PAP.0b013e31825c6b92. PMID: 22692283

Recent systematic reviews

Mansur G, Alsavaf MB, Pasquini L, Abouammo MD, Biswas C, Kumar P, Raval RR, Kobalka P, Carrau RL, Prevedello DM
Pituitary 2024 Oct;27(5):455-467. Epub 2024 Aug 14 doi: 10.1007/s11102-024-01441-9. PMID: 39141205Free PMC Article
Kardoust Parizi M, Iwata T, Kimura S, Janisch F, Abufaraj M, Karakiewicz PI, Enikeev D, Rapoport LM, Hutterer G, Shariat SF
Int J Mol Sci 2019 Mar 19;20(6) doi: 10.3390/ijms20061374. PMID: 30893781Free PMC Article

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