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Penile Neurofibroma

MedGen UID:
1685823
•Concept ID:
C5206669
•
Neoplastic Process

Definition

A neurofibroma that occurs in the penis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPenile Neurofibroma

Professional guidelines

PubMed

2022 European guideline for the management of balanoposthitis.
Edwards SK, Bunker CB, van der Snoek EM, van der Meijden WI
J Eur Acad Dermatol Venereol 2023 Jun;37(6):1104-1117. Epub 2023 Mar 21 doi: 10.1111/jdv.18954. PMID: 36942977
Extramammary Paget's Disease: Diagnosis, Pathogenesis, and Treatment with Focus on Recent Developments.
Ishizuki S, Nakamura Y
Curr Oncol 2021 Aug 5;28(4):2969-2986. doi: 10.3390/curroncol28040260. PMID: 34436026Free PMC Article
The Diagnosis and Treatment of Penile Cancer.
Hakenberg OW, Dräger DL, Erbersdobler A, Naumann CM, Jünemann KP, Protzel C
Dtsch Arztebl Int 2018 Sep 28;115(39):646-652. doi: 10.3238/arztebl.2018.0646. PMID: 30375327Free PMC Article

Recent clinical studies

Etiology

2022 European guideline for the management of balanoposthitis.
Edwards SK, Bunker CB, van der Snoek EM, van der Meijden WI
J Eur Acad Dermatol Venereol 2023 Jun;37(6):1104-1117. Epub 2023 Mar 21 doi: 10.1111/jdv.18954. PMID: 36942977
Human papillomavirus in men.
Gamboa-Hoil SI
Rev Int Androl 2023 Jan-Mar;21(1):100325. Epub 2022 Oct 17 doi: 10.1016/j.androl.2021.09.001. PMID: 36257902
Prostate Bed Delineation Guidelines for Postoperative Radiation Therapy: On Behalf Of The Francophone Group of Urological Radiation Therapy.
Robin S, Jolicoeur M, Palumbo S, Zilli T, Crehange G, De Hertogh O, Derashodian T, Sargos P, Salembier C, Supiot S, Udrescu C, Chapet O
Int J Radiat Oncol Biol Phys 2021 Apr 1;109(5):1243-1253. Epub 2020 Nov 10 doi: 10.1016/j.ijrobp.2020.11.010. PMID: 33186618
Penile preserving and reconstructive surgery in the management of penile cancer.
Burnett AL
Nat Rev Urol 2016 May;13(5):249-57. Epub 2016 Mar 22 doi: 10.1038/nrurol.2016.54. PMID: 27001013
Neonatal circumcision.
Niku SD, Stock JA, Kaplan GW
Urol Clin North Am 1995 Feb;22(1):57-65. PMID: 7855960

Diagnosis

2022 European guideline for the management of balanoposthitis.
Edwards SK, Bunker CB, van der Snoek EM, van der Meijden WI
J Eur Acad Dermatol Venereol 2023 Jun;37(6):1104-1117. Epub 2023 Mar 21 doi: 10.1111/jdv.18954. PMID: 36942977
Penile preserving and reconstructive surgery in the management of penile cancer.
Burnett AL
Nat Rev Urol 2016 May;13(5):249-57. Epub 2016 Mar 22 doi: 10.1038/nrurol.2016.54. PMID: 27001013
Magnetic resonance imaging of penile cancer.
Gupta S, Rajesh A
Magn Reson Imaging Clin N Am 2014 May;22(2):191-9, vi. doi: 10.1016/j.mric.2014.01.005. PMID: 24792677
The dysfunctional foreskin.
Porter WM, Bunker CB
Int J STD AIDS 2001 Apr;12(4):216-20. doi: 10.1258/0956462011922922. PMID: 11319970
Penile neurofibromas.
Kousseff BG, Hoover DL
Am J Med Genet 1999 Nov 5;87(1):1-5. doi: 10.1002/(sici)1096-8628(19991105)87:1<1::aid-ajmg1>3.0.co;2-q. PMID: 10528238

Therapy

2022 European guideline for the management of balanoposthitis.
Edwards SK, Bunker CB, van der Snoek EM, van der Meijden WI
J Eur Acad Dermatol Venereol 2023 Jun;37(6):1104-1117. Epub 2023 Mar 21 doi: 10.1111/jdv.18954. PMID: 36942977
Penile Cancer: Managing Sexual Dysfunction and Improving Quality of Life After Therapy.
Coba G, Patel T
Curr Urol Rep 2021 Jan 9;22(2):8. doi: 10.1007/s11934-020-01022-w. PMID: 33420966
Penile self-amputation.
Mumoli N, Giorgi-Pierfranceschi M, Porta C, Manzionna G, Barberio M
Intern Emerg Med 2018 Oct;13(7):1133. Epub 2018 Jun 26 doi: 10.1007/s11739-018-1899-6. PMID: 29943166
The dysfunctional foreskin.
Porter WM, Bunker CB
Int J STD AIDS 2001 Apr;12(4):216-20. doi: 10.1258/0956462011922922. PMID: 11319970
Neonatal circumcision.
Niku SD, Stock JA, Kaplan GW
Urol Clin North Am 1995 Feb;22(1):57-65. PMID: 7855960

Prognosis

Human papillomavirus in men.
Gamboa-Hoil SI
Rev Int Androl 2023 Jan-Mar;21(1):100325. Epub 2022 Oct 17 doi: 10.1016/j.androl.2021.09.001. PMID: 36257902
Preputial melanoma.
Tchernev G, Temelkova I
Wien Med Wochenschr 2021 Feb;171(1-2):41-42. Epub 2020 May 7 doi: 10.1007/s10354-020-00751-4. PMID: 32382854
Malignant Priapism - What Do We Know About It?
Marcu D, Iorga L, Mischianu D, Bacalbasa N, Balescu I, Bratu O
In Vivo 2020 Sep-Oct;34(5):2225-2232. doi: 10.21873/invivo.12033. PMID: 32871745Free PMC Article
Clinicopathological features of carcinoma of the distal penile urethra.
Corbishley CM, Rajab RM, Watkin NA
Semin Diagn Pathol 2015 May;32(3):238-44. Epub 2014 Dec 25 doi: 10.1053/j.semdp.2014.12.015. PMID: 25656527
Implications for human papillomavirus in penile cancer.
Flaherty A, Kim T, Giuliano A, Magliocco A, Hakky TS, Pagliaro LC, Spiess PE
Urol Oncol 2014 Jan;32(1):53.e1-8. Epub 2013 Nov 13 doi: 10.1016/j.urolonc.2013.08.010. PMID: 24239463

Clinical prediction guides

Assessment of PD-L1, TROP2, and nectin-4 expression in penile squamous cell carcinoma.
Tekin B, Cheville JC, Herrera Hernandez L, Negron V, Smith CY, Jenkins SM, Dasari S, Enninga EAL, Norgan AP, Menon S, Cubilla AL, Whaley RD, Jimenez RE, Thompson RH, Leibovich BC, Karnes RJ, Boorjian SA, Pagliaro LC, Erickson LA, Guo R, Gupta S
Hum Pathol 2023 Dec;142:42-50. Epub 2023 Nov 15 doi: 10.1016/j.humpath.2023.10.003. PMID: 37977513
Surgical and Functional Outcomes of Penile Amputation and Perineal Urethrostomy Configuration in Invasive Penile Cancer.
Falcone M, Preto M, Ferro I, Cirigliano L, Peretti F, Plamadeala N, Scavone M, Lavagno F, Oderda M, Gontero P
Urology 2023 Jul;177:227. Epub 2023 Apr 19 doi: 10.1016/j.urology.2023.04.005. PMID: 37085051
Prostate Bed Delineation Guidelines for Postoperative Radiation Therapy: On Behalf Of The Francophone Group of Urological Radiation Therapy.
Robin S, Jolicoeur M, Palumbo S, Zilli T, Crehange G, De Hertogh O, Derashodian T, Sargos P, Salembier C, Supiot S, Udrescu C, Chapet O
Int J Radiat Oncol Biol Phys 2021 Apr 1;109(5):1243-1253. Epub 2020 Nov 10 doi: 10.1016/j.ijrobp.2020.11.010. PMID: 33186618
Carcinoma of the urethra.
Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, Liu J, Baggerly K, Czerniak B
Hum Pathol 2018 Feb;72:35-44. Epub 2017 Aug 18 doi: 10.1016/j.humpath.2017.08.006. PMID: 28827100Free PMC Article
Review of in situ and invasive penile squamous cell carcinoma and associated non-neoplastic dermatological conditions.
Downes MR
J Clin Pathol 2015 May;68(5):333-40. doi: 10.1136/jclinpath-2015-202911. PMID: 25883161

Recent systematic reviews

Systematic Review and Meta-analysis of Minimally Invasive Procedures for Surgical Inguinal Nodal Staging in Penile Carcinoma.
Greco I, Fernandez-Pello S, Sakalis VI, Barreto L, Albersen M, Ayres B, Antunes Lopes T, Campi R, Crook J, García Perdomo HA, Johnstone PAS, Kailavasan M, Manzie K, Marcus JD, Necchi A, Oliveira P, Osborne J, Pagliaro LC, Parnham AS, Pettaway CA, Protzel C, Rumble RB, Sachdeva A, Sanchez Martinez DF, Zapala Ł, Tagawa ST, Spiess PE, Brouwer OR
Eur Urol Focus 2024 Jul;10(4):567-580. Epub 2023 Dec 9 doi: 10.1016/j.euf.2023.11.010. PMID: 38071107
Correlation between second and first primary cancer: systematic review and meta-analysis of 9 million cancer patients.
Wang X, Zeng M, Ju X, Lin A, Zhou C, Shen J, Liu Z, Tang B, Cheng Q, Wang Y, Zhang J, Luo P
Br J Surg 2024 Jan 3;111(1) doi: 10.1093/bjs/znad377. PMID: 38055899
Cowden syndrome and the PTEN hamartoma tumor syndrome: systematic review and revised diagnostic criteria.
Pilarski R, Burt R, Kohlman W, Pho L, Shannon KM, Swisher E
J Natl Cancer Inst 2013 Nov 6;105(21):1607-16. Epub 2013 Oct 17 doi: 10.1093/jnci/djt277. PMID: 24136893
Male circumcision and penile cancer: a systematic review and meta-analysis.
Larke NL, Thomas SL, dos Santos Silva I, Weiss HA
Cancer Causes Control 2011 Aug;22(8):1097-110. Epub 2011 Jun 22 doi: 10.1007/s10552-011-9785-9. PMID: 21695385Free PMC Article
Contemporary management of localized penile cancer.
Shapiro D, Shasha D, Tareen M, Tareen B
Expert Rev Anticancer Ther 2011 Jan;11(1):29-36. doi: 10.1586/era.10.209. PMID: 21166509

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