U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal CSF leucine concentration

MedGen UID:
1702927
•Concept ID:
C5139574
•
Finding
Synonym: Abnormal leucine levels in cerebrospinal fluid
 
HPO: HP:0500189

Definition

Any deviation from the normal concentration of leucine in the cerebrospinal fluid. [from HPO]

Recent clinical studies

Etiology

Clinical features of patients with anti-leucine-rich glioma inactivated-1 protein associated encephalitis: a Chinese case series.
Yang X, Li AN, Zhao XH, Liu XW, Wang SJ
Int J Neurosci 2019 Aug;129(8):754-761. Epub 2019 Feb 15 doi: 10.1080/00207454.2019.1567507. PMID: 30621547
Transforming growth factor-beta inhibits the expression of clock genes.
Gast H, Gordic S, Petrzilka S, Lopez M, Müller A, Gietl A, Hock C, Birchler T, Fontana A
Ann N Y Acad Sci 2012 Jul;1261:79-87. doi: 10.1111/j.1749-6632.2012.06640.x. PMID: 22823397
Cerebrospinal fluid amino acid levels in newborn infants with intracranial hemorrhage.
Yurdakök M, Coşkun T, Erdem G, Göktoğan S, Ozalp I, Tekinalp G
Acta Paediatr Jpn 1995 Dec;37(6):694-6. doi: 10.1111/j.1442-200x.1995.tb03406.x. PMID: 8775553
Fasting plasma and CSF amino acid levels in amyotrophic lateral sclerosis: a subtype analysis.
Camu W, Billiard M, Baldy-Moulinier M
Acta Neurol Scand 1993 Jul;88(1):51-5. doi: 10.1111/j.1600-0404.1993.tb04186.x. PMID: 8372631

Diagnosis

Cerebrospinal fluid metabolic profiles in multiple sclerosis and degenerative dementias obtained by high resolution proton magnetic resonance spectroscopy.
Nicoli F, Vion-Dury J, Confort-Gouny S, Maillet S, Gastaut JL, Cozzone PJ
C R Acad Sci III 1996 Jul;319(7):623-31. PMID: 9011324
Fasting plasma and CSF amino acid levels in amyotrophic lateral sclerosis: a subtype analysis.
Camu W, Billiard M, Baldy-Moulinier M
Acta Neurol Scand 1993 Jul;88(1):51-5. doi: 10.1111/j.1600-0404.1993.tb04186.x. PMID: 8372631

Therapy

Isolated biotin-resistant 3-methylcrotonyl-CoA carboxylase deficiency: long-term outcome in a case with neonatal onset.
Lehnert W, Niederhoff H, Suormala T, Baumgartner ER
Eur J Pediatr 1996 Jul;155(7):568-72. doi: 10.1007/BF01957906. PMID: 8831079

Prognosis

Clinical features of patients with anti-leucine-rich glioma inactivated-1 protein associated encephalitis: a Chinese case series.
Yang X, Li AN, Zhao XH, Liu XW, Wang SJ
Int J Neurosci 2019 Aug;129(8):754-761. Epub 2019 Feb 15 doi: 10.1080/00207454.2019.1567507. PMID: 30621547
Isolated biotin-resistant 3-methylcrotonyl-CoA carboxylase deficiency: long-term outcome in a case with neonatal onset.
Lehnert W, Niederhoff H, Suormala T, Baumgartner ER
Eur J Pediatr 1996 Jul;155(7):568-72. doi: 10.1007/BF01957906. PMID: 8831079

Clinical prediction guides

Clinical features of patients with anti-leucine-rich glioma inactivated-1 protein associated encephalitis: a Chinese case series.
Yang X, Li AN, Zhao XH, Liu XW, Wang SJ
Int J Neurosci 2019 Aug;129(8):754-761. Epub 2019 Feb 15 doi: 10.1080/00207454.2019.1567507. PMID: 30621547
Fasting plasma and CSF amino acid levels in amyotrophic lateral sclerosis: a subtype analysis.
Camu W, Billiard M, Baldy-Moulinier M
Acta Neurol Scand 1993 Jul;88(1):51-5. doi: 10.1111/j.1600-0404.1993.tb04186.x. PMID: 8372631

Supplemental Content

Table of contents

    Clinical resources

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...