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Uveal Nevus

MedGen UID:
1727578
•Concept ID:
C5420815
•
Neoplastic Process

Definition

A benign nevus derived from melanocytes of the uveal tract. Only a small percentage of cases progress to uveal melanoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUveal Nevus

Professional guidelines

PubMed

Ocular manifestations in phakomatosis pigmentovascularis: Current concepts on pathogenesis, diagnosis, and management.
Abdolrahimzadeh S, Pugi DM, de Paula A, Scuderi G
Surv Ophthalmol 2021 May-Jun;66(3):482-492. Epub 2020 Oct 13 doi: 10.1016/j.survophthal.2020.10.002. PMID: 33058925
Characterization, treatment, and outcome of uveal melanoma in the first two years of life.
Yousef YA, Alkilany M
Hematol Oncol Stem Cell Ther 2015 Mar;8(1):1-5. Epub 2014 Oct 6 doi: 10.1016/j.hemonc.2014.09.004. PMID: 25300563
Surgical treatment of ocular melanoma.
Hungerford JL
Melanoma Res 1993 Oct;3(5):305-12. doi: 10.1097/00008390-199310000-00001. PMID: 8292886

Recent clinical studies

Etiology

Involvement of mutant and wild-type CYSLTR2 in the development and progression of uveal nevi and melanoma.
Nell RJ, Menger NV, Versluis M, Luyten GPM, Verdijk RM, Madigan MC, Jager MJ, van der Velden PA
BMC Cancer 2021 Feb 15;21(1):164. doi: 10.1186/s12885-021-07865-x. PMID: 33588787Free PMC Article
Referral patterns of intraocular tumour patients to a dedicated Canadian ocular oncology department.
Law C, Krema H, Simpson ER
Can J Ophthalmol 2012 Jun;47(3):254-61. doi: 10.1016/j.jcjo.2012.03.047. PMID: 22687302

Diagnosis

Referral patterns of intraocular tumour patients to a dedicated Canadian ocular oncology department.
Law C, Krema H, Simpson ER
Can J Ophthalmol 2012 Jun;47(3):254-61. doi: 10.1016/j.jcjo.2012.03.047. PMID: 22687302

Prognosis

Involvement of mutant and wild-type CYSLTR2 in the development and progression of uveal nevi and melanoma.
Nell RJ, Menger NV, Versluis M, Luyten GPM, Verdijk RM, Madigan MC, Jager MJ, van der Velden PA
BMC Cancer 2021 Feb 15;21(1):164. doi: 10.1186/s12885-021-07865-x. PMID: 33588787Free PMC Article

Clinical prediction guides

Involvement of mutant and wild-type CYSLTR2 in the development and progression of uveal nevi and melanoma.
Nell RJ, Menger NV, Versluis M, Luyten GPM, Verdijk RM, Madigan MC, Jager MJ, van der Velden PA
BMC Cancer 2021 Feb 15;21(1):164. doi: 10.1186/s12885-021-07865-x. PMID: 33588787Free PMC Article

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