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Refractory Esophageal Squamous Cell Carcinoma

MedGen UID:
1734187
•Concept ID:
C5419205
•
Neoplastic Process

Definition

Esophageal squamous cell carcinoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Esophageal Squamous Cell Carcinoma

Professional guidelines

PubMed

Research Progress on Mechanism and Management of Adverse Drug Reactions of Anlotinib.
Li S, Wang H
Drug Des Devel Ther 2023;17:3429-3437. Epub 2023 Nov 15 doi: 10.2147/DDDT.S426898. PMID: 38024530Free PMC Article
Cryotherapy in the management of premalignant and malignant conditions of the esophagus.
Lal P, Thota PN
World J Gastroenterol 2018 Nov 21;24(43):4862-4869. doi: 10.3748/wjg.v24.i43.4862. PMID: 30487696Free PMC Article
Current treatment options for esophageal diseases.
Martínek J, Akiyama JI, Vacková Z, Furnari M, Savarino E, Weijs TJ, Valitova E, van der Horst S, Ruurda JP, Goense L, Triadafilopoulos G
Ann N Y Acad Sci 2016 Oct;1381(1):139-151. Epub 2016 Jul 8 doi: 10.1111/nyas.13146. PMID: 27391867

Recent clinical studies

Etiology

A Phase II Study of Apatinib in Patients with Chemotherapy-Refractory Esophageal Squamous Cell Carcinoma (ESO-Shanghai 11).
Chu L, Chen Y, Liu Q, Liang F, Wang S, Liu Q, Yu H, Wu X, Zhang J, Deng J, Ai D, Zhu Z, Nie Y, Zhao K
Oncologist 2021 Jun;26(6):e925-e935. Epub 2021 Feb 1 doi: 10.1002/onco.13668. PMID: 33393167Free PMC Article

Diagnosis

Multicenter phase II study of trifluridine/tipiracil for esophageal squamous carcinoma refractory/intolerant to 5-fluorouracil, platinum compounds, and taxanes: the ECTAS study.
Mori Y, Kikuchi O, Horimatsu T, Hara H, Hironaka S, Kojima T, Kato K, Tsushima T, Ishihara R, Mukai K, Uozumi R, Tada H, Kasai H, Kawaguchi A, Muto M
Esophagus 2022 Jul;19(3):444-451. Epub 2022 Jan 20 doi: 10.1007/s10388-021-00905-2. PMID: 35050435
Refractory solitary cervical lymph node metastasis after esophageal squamous cell carcinoma surgery and its successful treatment with immune checkpoint inhibitor: A case report and literature review.
Song W, Wang H, Tian Y, Liu S, Chen X, Cui J, Zhao Y
Medicine (Baltimore) 2020 Mar;99(10):e19440. doi: 10.1097/MD.0000000000019440. PMID: 32150096Free PMC Article

Therapy

A phase 2 study of spartalizumab (PDR001) among patients with recurrent or metastatic esophageal squamous cell carcinoma (KCSG HN18-17, K-MASTER project 12).
Lee DK, Park SR, Kim YH, Lee YG, Shin SJ, Ahn BC, Lee SS, Lim SM, Kim HR, Cho BC, Hong MH
Oncoimmunology 2024;13(1):2371563. Epub 2024 Jun 24 doi: 10.1080/2162402X.2024.2371563. PMID: 38919826Free PMC Article
Multicenter phase II study of trifluridine/tipiracil for esophageal squamous carcinoma refractory/intolerant to 5-fluorouracil, platinum compounds, and taxanes: the ECTAS study.
Mori Y, Kikuchi O, Horimatsu T, Hara H, Hironaka S, Kojima T, Kato K, Tsushima T, Ishihara R, Mukai K, Uozumi R, Tada H, Kasai H, Kawaguchi A, Muto M
Esophagus 2022 Jul;19(3):444-451. Epub 2022 Jan 20 doi: 10.1007/s10388-021-00905-2. PMID: 35050435
A Phase II Study of Apatinib in Patients with Chemotherapy-Refractory Esophageal Squamous Cell Carcinoma (ESO-Shanghai 11).
Chu L, Chen Y, Liu Q, Liang F, Wang S, Liu Q, Yu H, Wu X, Zhang J, Deng J, Ai D, Zhu Z, Nie Y, Zhao K
Oncologist 2021 Jun;26(6):e925-e935. Epub 2021 Feb 1 doi: 10.1002/onco.13668. PMID: 33393167Free PMC Article
Refractory solitary cervical lymph node metastasis after esophageal squamous cell carcinoma surgery and its successful treatment with immune checkpoint inhibitor: A case report and literature review.
Song W, Wang H, Tian Y, Liu S, Chen X, Cui J, Zhao Y
Medicine (Baltimore) 2020 Mar;99(10):e19440. doi: 10.1097/MD.0000000000019440. PMID: 32150096Free PMC Article

Prognosis

A phase 2 study of spartalizumab (PDR001) among patients with recurrent or metastatic esophageal squamous cell carcinoma (KCSG HN18-17, K-MASTER project 12).
Lee DK, Park SR, Kim YH, Lee YG, Shin SJ, Ahn BC, Lee SS, Lim SM, Kim HR, Cho BC, Hong MH
Oncoimmunology 2024;13(1):2371563. Epub 2024 Jun 24 doi: 10.1080/2162402X.2024.2371563. PMID: 38919826Free PMC Article
Refractory solitary cervical lymph node metastasis after esophageal squamous cell carcinoma surgery and its successful treatment with immune checkpoint inhibitor: A case report and literature review.
Song W, Wang H, Tian Y, Liu S, Chen X, Cui J, Zhao Y
Medicine (Baltimore) 2020 Mar;99(10):e19440. doi: 10.1097/MD.0000000000019440. PMID: 32150096Free PMC Article

Clinical prediction guides

A phase 2 study of spartalizumab (PDR001) among patients with recurrent or metastatic esophageal squamous cell carcinoma (KCSG HN18-17, K-MASTER project 12).
Lee DK, Park SR, Kim YH, Lee YG, Shin SJ, Ahn BC, Lee SS, Lim SM, Kim HR, Cho BC, Hong MH
Oncoimmunology 2024;13(1):2371563. Epub 2024 Jun 24 doi: 10.1080/2162402X.2024.2371563. PMID: 38919826Free PMC Article
A Phase II Study of Apatinib in Patients with Chemotherapy-Refractory Esophageal Squamous Cell Carcinoma (ESO-Shanghai 11).
Chu L, Chen Y, Liu Q, Liang F, Wang S, Liu Q, Yu H, Wu X, Zhang J, Deng J, Ai D, Zhu Z, Nie Y, Zhao K
Oncologist 2021 Jun;26(6):e925-e935. Epub 2021 Feb 1 doi: 10.1002/onco.13668. PMID: 33393167Free PMC Article
Refractory solitary cervical lymph node metastasis after esophageal squamous cell carcinoma surgery and its successful treatment with immune checkpoint inhibitor: A case report and literature review.
Song W, Wang H, Tian Y, Liu S, Chen X, Cui J, Zhao Y
Medicine (Baltimore) 2020 Mar;99(10):e19440. doi: 10.1097/MD.0000000000019440. PMID: 32150096Free PMC Article

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