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Locally Advanced Renal Pelvis Carcinoma

MedGen UID:
1750328
•Concept ID:
C5419561
•
Neoplastic Process

Definition

Renal pelvis carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Renal Pelvis Carcinoma

Professional guidelines

PubMed

Optimal management of recurrent and metastatic upper tract urothelial carcinoma: Implications of intensity modulated radiation therapy.
Kim MS, Koom WS, Cho JH, Kim SY, Lee IJ
Radiat Oncol 2022 Mar 9;17(1):51. doi: 10.1186/s13014-022-02020-7. PMID: 35264197Free PMC Article
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
The role of chemotherapy in the treatment of urothelial cell carcinoma of the upper urinary tract (UUT-UCC).
Audenet F, Yates DR, Cussenot O, Rouprêt M
Urol Oncol 2013 May;31(4):407-13. Epub 2010 Sep 29 doi: 10.1016/j.urolonc.2010.07.016. PMID: 20884249

Recent clinical studies

Etiology

Design and rationale of a single-arm phase II study of neoadjuvant Durvalumab and Gemcitabine associated with Cisplatin or Carboplatin for upper urinary tract urothelial cancer: the iNDUCT trial (NCT04617756).
Calleris G, Rouprêt M, Seisen T, Bendjeddou L, Chevallier T, Masson-Lecomte A, Thibault C, Neuzillet Y, Audenet F, Xylinas E, Houédé N
World J Urol 2023 Dec;41(12):3413-3420. Epub 2023 Sep 12 doi: 10.1007/s00345-023-04596-5. PMID: 37698632
Adjuvant Radiotherapy for Upper Tract Urothelial Carcinoma: Systematic Review and Meta-Analysis.
Zalay O, Yan M, Sigurdson S, Malone S, Vera-Badillo FE, Mahmud A
Curr Oncol 2022 Dec 20;30(1):19-36. doi: 10.3390/curroncol30010002. PMID: 36661651Free PMC Article
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Adjuvant Sandwich Chemotherapy Plus Radiotherapy vs Adjuvant Chemotherapy Alone for Locally Advanced Bladder Cancer After Radical Cystectomy: A Randomized Phase 2 Trial.
Zaghloul MS, Christodouleas JP, Smith A, Abdallah A, William H, Khaled HM, Hwang WT, Baumann BC
JAMA Surg 2018 Jan 17;153(1):e174591. doi: 10.1001/jamasurg.2017.4591. PMID: 29188298Free PMC Article
Renal cancer.
Corgna E, Betti M, Gatta G, Roila F, De Mulder PH
Crit Rev Oncol Hematol 2007 Dec;64(3):247-62. Epub 2007 Jul 26 doi: 10.1016/j.critrevonc.2007.04.007. PMID: 17662611

Diagnosis

Design and rationale of a single-arm phase II study of neoadjuvant Durvalumab and Gemcitabine associated with Cisplatin or Carboplatin for upper urinary tract urothelial cancer: the iNDUCT trial (NCT04617756).
Calleris G, Rouprêt M, Seisen T, Bendjeddou L, Chevallier T, Masson-Lecomte A, Thibault C, Neuzillet Y, Audenet F, Xylinas E, Houédé N
World J Urol 2023 Dec;41(12):3413-3420. Epub 2023 Sep 12 doi: 10.1007/s00345-023-04596-5. PMID: 37698632
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Recent advances in upper tract urothelial carcinomas: From bench to clinics.
Shao IH, Chang YH, Pang ST
Int J Urol 2019 Feb;26(2):148-159. Epub 2018 Oct 29 doi: 10.1111/iju.13826. PMID: 30372791
Renal cancer.
Corgna E, Betti M, Gatta G, Roila F, De Mulder PH
Crit Rev Oncol Hematol 2007 Dec;64(3):247-62. Epub 2007 Jul 26 doi: 10.1016/j.critrevonc.2007.04.007. PMID: 17662611
Ureteroscopic resection of upper-tract transitional-cell carcinoma.
Ho KL, Chow GK
J Endourol 2005 Sep;19(7):841-8. doi: 10.1089/end.2005.19.841. PMID: 16190841

Therapy

Design and rationale of a single-arm phase II study of neoadjuvant Durvalumab and Gemcitabine associated with Cisplatin or Carboplatin for upper urinary tract urothelial cancer: the iNDUCT trial (NCT04617756).
Calleris G, Rouprêt M, Seisen T, Bendjeddou L, Chevallier T, Masson-Lecomte A, Thibault C, Neuzillet Y, Audenet F, Xylinas E, Houédé N
World J Urol 2023 Dec;41(12):3413-3420. Epub 2023 Sep 12 doi: 10.1007/s00345-023-04596-5. PMID: 37698632
Adjuvant Radiotherapy for Upper Tract Urothelial Carcinoma: Systematic Review and Meta-Analysis.
Zalay O, Yan M, Sigurdson S, Malone S, Vera-Badillo FE, Mahmud A
Curr Oncol 2022 Dec 20;30(1):19-36. doi: 10.3390/curroncol30010002. PMID: 36661651Free PMC Article
Immune checkpoint inhibition in upper tract urothelial carcinoma.
Califano G, Ouzaid I, Verze P, Hermieu JF, Mirone V, Xylinas E
World J Urol 2021 May;39(5):1357-1367. Epub 2020 Oct 31 doi: 10.1007/s00345-020-03502-7. PMID: 33128595
Adjuvant Sandwich Chemotherapy Plus Radiotherapy vs Adjuvant Chemotherapy Alone for Locally Advanced Bladder Cancer After Radical Cystectomy: A Randomized Phase 2 Trial.
Zaghloul MS, Christodouleas JP, Smith A, Abdallah A, William H, Khaled HM, Hwang WT, Baumann BC
JAMA Surg 2018 Jan 17;153(1):e174591. doi: 10.1001/jamasurg.2017.4591. PMID: 29188298Free PMC Article
Ureteroscopic resection of upper-tract transitional-cell carcinoma.
Ho KL, Chow GK
J Endourol 2005 Sep;19(7):841-8. doi: 10.1089/end.2005.19.841. PMID: 16190841

Prognosis

Advanced renal pelvis carcinoma patient with an ERBB2 insertion mutation: a case report.
Shang P, Lou C, Yin L, Tao C, Dong Y, Yang G, Yuan Z
J Int Med Res 2023 Nov;51(11):3000605231204502. doi: 10.1177/03000605231204502. PMID: 37917812Free PMC Article
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Recent advances in upper tract urothelial carcinomas: From bench to clinics.
Shao IH, Chang YH, Pang ST
Int J Urol 2019 Feb;26(2):148-159. Epub 2018 Oct 29 doi: 10.1111/iju.13826. PMID: 30372791
Renal cancer.
Corgna E, Betti M, Gatta G, Roila F, De Mulder PH
Crit Rev Oncol Hematol 2007 Dec;64(3):247-62. Epub 2007 Jul 26 doi: 10.1016/j.critrevonc.2007.04.007. PMID: 17662611
Transitional cell carcinoma of the ureter and renal pelvis.
Kirkali Z, Tuzel E
Crit Rev Oncol Hematol 2003 Aug;47(2):155-69. doi: 10.1016/s1040-8428(03)00079-9. PMID: 12900009

Clinical prediction guides

Clinicopathologic Analysis of Micropapillary Urothelial Carcinoma of the Upper Urinary Tract: Implications for HER2-Targeted Therapy.
Chou LP, Hsu CW, Yang SF, Lee CT, Ou YC, Lin KC, Hu CY, Jou YC, Tsai YS, Chow NH
Clin Genitourin Cancer 2023 Aug;21(4):508.e1-508.e10. Epub 2023 Apr 20 doi: 10.1016/j.clgc.2023.04.002. PMID: 37183125
Tailored immunotherapy approach with nivolumab with or without ipilimumab in patients with advanced transitional cell carcinoma after platinum-based chemotherapy (TITAN-TCC): a multicentre, single-arm, phase 2 trial.
Grimm MO, Grün CB, Niegisch G, Pichler M, Roghmann F, Schmitz-Dräger B, Baretton G, Schmitz M, Bolenz C, Foller S, Leucht K, Schumacher U, Schostak M, Meran J, Loidl W, Zengerling F
Lancet Oncol 2023 Apr;24(4):347-359. Epub 2023 Feb 28 doi: 10.1016/S1470-2045(23)00053-0. PMID: 36868252
High Serum CA19-9 Concentration Indicates High Chemosensitivity and Better Survival in Advanced Urothelial Carcinoma.
Yaegashi H, Izumi K, Kadomoto S, Naito R, Makino T, Iwamoto H, Nohara T, Shigehara K, Kadono Y, Mizokami A
Anticancer Res 2019 Jan;39(1):375-380. doi: 10.21873/anticanres.13122. PMID: 30591483
Preoperative T categorization and prediction of histopathologic grading of urothelial carcinoma in renal pelvis using diffusion-weighted MRI.
Akita H, Jinzaki M, Kikuchi E, Sugiura H, Akita A, Mikami S, Kuribayashi S
AJR Am J Roentgenol 2011 Nov;197(5):1130-6. doi: 10.2214/AJR.10.6299. PMID: 22021505
Urothelial carcinoma of the renal pelvis: a clinicopathologic study of 130 cases.
Olgac S, Mazumdar M, Dalbagni G, Reuter VE
Am J Surg Pathol 2004 Dec;28(12):1545-52. doi: 10.1097/00000478-200412000-00001. PMID: 15577672

Recent systematic reviews

Adjuvant Radiotherapy for Upper Tract Urothelial Carcinoma: Systematic Review and Meta-Analysis.
Zalay O, Yan M, Sigurdson S, Malone S, Vera-Badillo FE, Mahmud A
Curr Oncol 2022 Dec 20;30(1):19-36. doi: 10.3390/curroncol30010002. PMID: 36661651Free PMC Article
Radical nephroureterectomy versus endoscopic procedures for the treatment of localised upper tract urothelial carcinoma: a meta-analysis and a systematic review of current evidence from comparative studies.
Yakoubi R, Colin P, Seisen T, Léon P, Nison L, Bozzini G, Shariat SF, Rouprêt M
Eur J Surg Oncol 2014 Dec;40(12):1629-34. Epub 2014 Jul 25 doi: 10.1016/j.ejso.2014.06.007. PMID: 25108813

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