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Paratesticular Epithelioid Mesothelioma

MedGen UID:
1772142
•Concept ID:
C5420296
•
Neoplastic Process
Synonyms: Testicular Epithelioid Mesothelioma; Tunica Vaginalis Epithelioid Mesothelioma

Definition

A rare malignant mesothelioma arising from the tunica vaginalis. It is characterized by the presence of cells with epithelioid morphology. The epithelioid cells usually have eosinophilic cytoplasm, bland nuclei, and form tubulopapillary, microglandular, or sheet-like patterns. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParatesticular Epithelioid Mesothelioma

Recent clinical studies

Etiology

Role of Fine Needle Aspiration Cytology in Paratesticular Neoplasms-A Case Reports-Based Systematic Review.
Nigam JS, Bharti JN, Pradeep I, Rath A
Diagn Cytopathol 2024 Dec;52(12):779-788. Epub 2024 Sep 19 doi: 10.1002/dc.25404. PMID: 39295546
Mesothelioma of the tunica vaginalis testis.
Butnor KJ, Pavlisko EN, Sporn TA, Roggli VL
Hum Pathol 2019 Oct;92:48-58. Epub 2019 Aug 1 doi: 10.1016/j.humpath.2019.07.009. PMID: 31376434

Diagnosis

Local Cutaneous Scrotal Involvement of Paratesticular Mesothelioma.
Maniam G, Tekin B, Gupta S, Nguyen G, Agrawal S
Am J Dermatopathol 2024 Oct 1;46(10):e91-e95. Epub 2024 Jul 12 doi: 10.1097/DAD.0000000000002802. PMID: 39008503
Molecular and immunohistochemical characterisation of mesothelioma of the tunica vaginalis().
Anderson WJ, Sholl LM, Fletcher CDM, Schulte S, Wang LJ, Maclean FM, Hirsch MS
Histopathology 2022 Jul;81(1):65-76. Epub 2022 May 10 doi: 10.1111/his.14669. PMID: 35460532
Mesothelioma of the tunica vaginalis testis.
Butnor KJ, Pavlisko EN, Sporn TA, Roggli VL
Hum Pathol 2019 Oct;92:48-58. Epub 2019 Aug 1 doi: 10.1016/j.humpath.2019.07.009. PMID: 31376434
Primary adenomatoid tumor of the testis: report of a case and review of literature.
Sheng B, Zhang YP, Wei HH, Ma M, Nan X
Int J Clin Exp Pathol 2015;8(5):5914-8. Epub 2015 May 1 PMID: 26191318Free PMC Article
Epithelioid malignant mesothelioma of tunica vaginalis with deciduoid features: an unusual malignancy clinically masquerading an inguinal hernia.
Ahmed S, Menon S, Desai S
Indian J Pathol Microbiol 2012 Jan-Mar;55(1):89-91. doi: 10.4103/0377-4929.94868. PMID: 22499310

Prognosis

Malignant Para-Testicular Mesothelioma: A Rare Presentation in the Tunica Vaginalis of an Elderly Male With No Prior Asbestos Exposure.
Shaker N, Blankenship H, Shaker N, Ben Musa R, Niu S, Alrohaibani A, Mansoor I, Abu Shakra R, Sangueza OP
Int J Surg Pathol 2024 Sep;32(6):1117-1122. Epub 2024 Jan 2 doi: 10.1177/10668969231215426. PMID: 38166430
Mesothelioma of the tunica vaginalis testis.
Butnor KJ, Pavlisko EN, Sporn TA, Roggli VL
Hum Pathol 2019 Oct;92:48-58. Epub 2019 Aug 1 doi: 10.1016/j.humpath.2019.07.009. PMID: 31376434
Primary adenomatoid tumor of the testis: report of a case and review of literature.
Sheng B, Zhang YP, Wei HH, Ma M, Nan X
Int J Clin Exp Pathol 2015;8(5):5914-8. Epub 2015 May 1 PMID: 26191318Free PMC Article

Clinical prediction guides

Role of Fine Needle Aspiration Cytology in Paratesticular Neoplasms-A Case Reports-Based Systematic Review.
Nigam JS, Bharti JN, Pradeep I, Rath A
Diagn Cytopathol 2024 Dec;52(12):779-788. Epub 2024 Sep 19 doi: 10.1002/dc.25404. PMID: 39295546
Primary adenomatoid tumor of the testis: report of a case and review of literature.
Sheng B, Zhang YP, Wei HH, Ma M, Nan X
Int J Clin Exp Pathol 2015;8(5):5914-8. Epub 2015 May 1 PMID: 26191318Free PMC Article

Recent systematic reviews

Role of Fine Needle Aspiration Cytology in Paratesticular Neoplasms-A Case Reports-Based Systematic Review.
Nigam JS, Bharti JN, Pradeep I, Rath A
Diagn Cytopathol 2024 Dec;52(12):779-788. Epub 2024 Sep 19 doi: 10.1002/dc.25404. PMID: 39295546

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