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Reversible airflow obstruction

MedGen UID:
1779583
Concept ID:
C5539668
Finding
Synonym: Reversible pulmonary obstruction
 
HPO: HP:0033540

Definition

Airflow obstruction with a significant response to a bronchodilator defined as an increase in FEV1 and/or FVC by 12 percent or more and by at least 200 mL. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVReversible airflow obstruction

Professional guidelines

PubMed

Shipp CL, Gergen PJ, Gern JE, Matsui EC, Guilbert TW
J Allergy Clin Immunol Pract 2023 Jan;11(1):9-18. Epub 2022 Nov 9 doi: 10.1016/j.jaip.2022.10.031. PMID: 36334702
Zatloukal J, Brat K, Neumannova K, Volakova E, Hejduk K, Kocova E, Kudela O, Kopecky M, Plutinsky M, Koblizek V
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2020 Dec;164(4):325-356. doi: 10.5507/bp.2020.056. PMID: 33325455
Bettoncelli G, Blasi F, Brusasco V, Centanni S, Corrado A, De Benedetto F, De Michele F, Di Maria GU, Donner CF, Falcone F, Mereu C, Nardini S, Pasqua F, Polverino M, Rossi A, Sanguinetti CM
Sarcoidosis Vasc Diffuse Lung Dis 2014 May 12;31 Suppl 1:3-21. PMID: 24820963

Recent clinical studies

Etiology

Shipp CL, Gergen PJ, Gern JE, Matsui EC, Guilbert TW
J Allergy Clin Immunol Pract 2023 Jan;11(1):9-18. Epub 2022 Nov 9 doi: 10.1016/j.jaip.2022.10.031. PMID: 36334702
Zatloukal J, Brat K, Neumannova K, Volakova E, Hejduk K, Kocova E, Kudela O, Kopecky M, Plutinsky M, Koblizek V
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2020 Dec;164(4):325-356. doi: 10.5507/bp.2020.056. PMID: 33325455
Burdon J
Aust Fam Physician 2015 Aug;44(8):554-7. PMID: 26510141
Leung TF, Ko FW, Wong GW
Ther Adv Respir Dis 2013 Oct;7(5):297-308. Epub 2013 Aug 1 doi: 10.1177/1753465813496863. PMID: 23907809
Sims JM
Dimens Crit Care Nurs 2006 Nov-Dec;25(6):264-8. doi: 10.1097/00003465-200611000-00004. PMID: 17122656

Diagnosis

Shipp CL, Gergen PJ, Gern JE, Matsui EC, Guilbert TW
J Allergy Clin Immunol Pract 2023 Jan;11(1):9-18. Epub 2022 Nov 9 doi: 10.1016/j.jaip.2022.10.031. PMID: 36334702
Alashkar Alhamwe B, Potaczek DP, Miethe S, Alhamdan F, Hintz L, Magomedov A, Garn H
Int J Mol Sci 2021 May 7;22(9) doi: 10.3390/ijms22094984. PMID: 34067156Free PMC Article
Zatloukal J, Brat K, Neumannova K, Volakova E, Hejduk K, Kocova E, Kudela O, Kopecky M, Plutinsky M, Koblizek V
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2020 Dec;164(4):325-356. doi: 10.5507/bp.2020.056. PMID: 33325455
Kercsmar CM, Shipp C
Immunol Allergy Clin North Am 2019 May;39(2):191-204. doi: 10.1016/j.iac.2018.12.004. PMID: 30954170
Sims JM
Dimens Crit Care Nurs 2006 Nov-Dec;25(6):264-8. doi: 10.1097/00003465-200611000-00004. PMID: 17122656

Therapy

Gupta V, Singh D
Expert Rev Respir Med 2012 Dec;6(6):581-8. doi: 10.1586/ers.12.61. PMID: 23234445
Tilley SL
Handb Exp Pharmacol 2011;(200):439-56. doi: 10.1007/978-3-642-13443-2_17. PMID: 20859807
McCormack FX
Chest 2008 Feb;133(2):507-16. doi: 10.1378/chest.07-0898. PMID: 18252917
Sims JM
Dimens Crit Care Nurs 2006 Nov-Dec;25(6):264-8. doi: 10.1097/00003465-200611000-00004. PMID: 17122656
Newhouse MT, Dolovich M
Chest 1987 May;91(5 Suppl):58S-64S. PMID: 3552472

Prognosis

Sharma S, Yang IV, Schwartz DA
J Allergy Clin Immunol 2022 Aug;150(2):259-265. Epub 2022 Jun 16 doi: 10.1016/j.jaci.2022.06.002. PMID: 35717251Free PMC Article
Zatloukal J, Brat K, Neumannova K, Volakova E, Hejduk K, Kocova E, Kudela O, Kopecky M, Plutinsky M, Koblizek V
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2020 Dec;164(4):325-356. doi: 10.5507/bp.2020.056. PMID: 33325455
Yang CL, Gaffin JM, Radhakrishnan D
Paediatr Respir Rev 2019 Feb;29:25-30. Epub 2018 Oct 24 doi: 10.1016/j.prrv.2018.10.003. PMID: 30528365Free PMC Article
Leung TF, Ko FW, Wong GW
Ther Adv Respir Dis 2013 Oct;7(5):297-308. Epub 2013 Aug 1 doi: 10.1177/1753465813496863. PMID: 23907809
McCormack FX
Chest 2008 Feb;133(2):507-16. doi: 10.1378/chest.07-0898. PMID: 18252917

Clinical prediction guides

Buhr RG, Barjaktarevic IZ, Quibrera PM, Bateman LA, Bleecker ER, Couper DJ, Curtis JL, Dolezal BA, Han MK, Hansel NN, Krishnan JA, Martinez FJ, McKleroy W, Paine R 3rd, Rennard SI, Tashkin DP, Woodruff PG, Kanner RE, Cooper CB; SPIROMICS Investigators
Am J Respir Crit Care Med 2022 Sep 1;206(5):554-562. doi: 10.1164/rccm.202201-0094OC. PMID: 35549640Free PMC Article
Yang CL, Gaffin JM, Radhakrishnan D
Paediatr Respir Rev 2019 Feb;29:25-30. Epub 2018 Oct 24 doi: 10.1016/j.prrv.2018.10.003. PMID: 30528365Free PMC Article
Patel TR, Sur S
Curr Opin Allergy Clin Immunol 2017 Feb;17(1):42-49. doi: 10.1097/ACI.0000000000000336. PMID: 27906698
Bettoncelli G, Blasi F, Brusasco V, Centanni S, Corrado A, De Benedetto F, De Michele F, Di Maria GU, Donner CF, Falcone F, Mereu C, Nardini S, Pasqua F, Polverino M, Rossi A, Sanguinetti CM
Sarcoidosis Vasc Diffuse Lung Dis 2014 May 12;31 Suppl 1:3-21. PMID: 24820963
Tilley SL
Handb Exp Pharmacol 2011;(200):439-56. doi: 10.1007/978-3-642-13443-2_17. PMID: 20859807

Recent systematic reviews

Dretzke J, Blissett D, Dave C, Mukherjee R, Price M, Bayliss S, Wu X, Jordan R, Jowett S, Turner AM, Moore D
Health Technol Assess 2015 Oct;19(81):1-246. doi: 10.3310/hta19810. PMID: 26470875Free PMC Article

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