U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Lacrimal Gland Oncocytoma

MedGen UID:
1782541
•Concept ID:
C5446385
•
Neoplastic Process

Definition

A benign epithelial neoplasm that arises from the lacrimal gland. It is characterized by the presence of oncocytic cells with abundant eosinophilic and granular cytoplasm. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLacrimal Gland Oncocytoma

Professional guidelines

PubMed

Epithelial tumors of the lacrimal gland: clinico-pathologic correlation and management.
Riedel KG, Markl A, Hasenfratz G, Kampik A, Stefani FH, Lund OE
Neurosurg Rev 1990;13(4):289-98. doi: 10.1007/BF00346367. PMID: 2177857

Recent clinical studies

Etiology

Accessory lacrimal gland tumours of the eye region.
Mulay K, Rasmussen PK, Aggarwal E, Honavar SG, Heegaard S
Acta Ophthalmol 2018 Nov;96(7):e772-e775. Epub 2018 May 31 doi: 10.1111/aos.13712. PMID: 29855174
Nasolacrimal duct tumours in the era of endoscopic dacryocystorhinostomy: literature review.
Tanweer F, Mahkamova K, Harkness P
J Laryngol Otol 2013 Jul;127(7):670-5. Epub 2013 Jun 12 doi: 10.1017/S0022215113001163. PMID: 23756574
Oncocytoma of the peripunctum.
Imaizumi M, Nakatsuka K
Int Ophthalmol 2005 Jun;26(3):111-3. Epub 2006 Nov 8 doi: 10.1007/s10792-006-9008-7. PMID: 17091220
Ostensible oncocytoma of accessory lacrimal glands.
Pecorella I, Garner A
Histopathology 1997 Mar;30(3):264-70. doi: 10.1046/j.1365-2559.1997.d01-601.x. PMID: 9088957
Epithelial tumors of the lacrimal gland: clinico-pathologic correlation and management.
Riedel KG, Markl A, Hasenfratz G, Kampik A, Stefani FH, Lund OE
Neurosurg Rev 1990;13(4):289-98. doi: 10.1007/BF00346367. PMID: 2177857

Diagnosis

Primary Lacrimal Gland Oncocytoma Associated With Hypervascularity: A Case Report With Imaging and Immunohistochemical Characterization.
Sweeney AR, Allen RC
Ophthalmic Plast Reconstr Surg 2021 May-Jun 01;37(3S):S128-S130. doi: 10.1097/IOP.0000000000001792. PMID: 33009324
Oncocytoma of the lacrimal gland: a case report.
Fenelon EM, Balby IT, Neves NTD, Figueiredo F, Duarte ECB, Tzelikis PF
Arq Bras Oftalmol 2017 Mar-Apr;80(2):128-130. doi: 10.5935/0004-2749.20170031. PMID: 28591289
A systematic review of sinonasal oncocytomas and oncocytic carcinomas: Diagnosis, management, and technical considerations.
Hodzic Z, Rowan NR, Kashiwazaki R, Willson TJ, Wang EW, Lee SE
Int Forum Allergy Rhinol 2017 May;7(5):514-524. Epub 2017 Jan 16 doi: 10.1002/alr.21902. PMID: 28092140
Oncocytoma of the lacrimal gland: case report and review of the literature.
Calle CA, Castillo IG, Eagle RC, Daza MT
Orbit 2006 Sep;25(3):243-7. doi: 10.1080/01676830600575543. PMID: 16987774
Epithelial tumors of the lacrimal gland: clinico-pathologic correlation and management.
Riedel KG, Markl A, Hasenfratz G, Kampik A, Stefani FH, Lund OE
Neurosurg Rev 1990;13(4):289-98. doi: 10.1007/BF00346367. PMID: 2177857

Therapy

Nasal oncocytoma causing unilateral epiphora in an elderly patient: the vital role of nasendoscopy.
Murphy DC, Alfiky M, Prinsley P
BMJ Case Rep 2018 Mar 9;2018 doi: 10.1136/bcr-2017-223183. PMID: 29523610Free PMC Article

Prognosis

Malignant oncocytoma of the lacrimal sac as an unusual cause of epiphora.
Yuen HK, Cheuk W, Cheng AC, Anh C, Chan N
Ophthalmic Plast Reconstr Surg 2007 Jan-Feb;23(1):70-2. doi: 10.1097/IOP.0b013e31802dd7f4. PMID: 17237701
Oncocytoma of the peripunctum.
Imaizumi M, Nakatsuka K
Int Ophthalmol 2005 Jun;26(3):111-3. Epub 2006 Nov 8 doi: 10.1007/s10792-006-9008-7. PMID: 17091220
Oncocytic adenomatous hyperplasia of the lacrimal sac: a case report and review of the literature.
Chen LJ, Liao SL, Kao SC, Wu CT, Hou PK, Chen MS
Ophthalmic Plast Reconstr Surg 1998 Nov;14(6):436-40. doi: 10.1097/00002341-199811000-00008. PMID: 9842564
Clinically suspected primary acquired nasolacrimal duct obstruction: clinicopathologic review of 150 patients.
Tucker N, Chow D, Stockl F, Codère F, Burnier M
Ophthalmology 1997 Nov;104(11):1882-6. doi: 10.1016/s0161-6420(97)30012-8. PMID: 9373121
Epithelial tumors of the lacrimal gland: clinico-pathologic correlation and management.
Riedel KG, Markl A, Hasenfratz G, Kampik A, Stefani FH, Lund OE
Neurosurg Rev 1990;13(4):289-98. doi: 10.1007/BF00346367. PMID: 2177857

Clinical prediction guides

Clinico-pathological correlation of lacrimal caruncle tumors: a retrospective analysis over 22 years at the University Eye Hospital Bonn.
Clemens AC, Loeffler KU, Holz FG, Herwig-Carl MC
Graefes Arch Clin Exp Ophthalmol 2022 Apr;260(4):1415-1425. Epub 2021 Oct 28 doi: 10.1007/s00417-021-05464-x. PMID: 34709452Free PMC Article
Accessory lacrimal gland tumours of the eye region.
Mulay K, Rasmussen PK, Aggarwal E, Honavar SG, Heegaard S
Acta Ophthalmol 2018 Nov;96(7):e772-e775. Epub 2018 May 31 doi: 10.1111/aos.13712. PMID: 29855174
Oncocytoma of the lacrimal gland: a case report.
Fenelon EM, Balby IT, Neves NTD, Figueiredo F, Duarte ECB, Tzelikis PF
Arq Bras Oftalmol 2017 Mar-Apr;80(2):128-130. doi: 10.5935/0004-2749.20170031. PMID: 28591289
Nasolacrimal duct obstruction caused by oncocytic carcinoma.
Jung JH, Shin DH, Cho KS, Choi HY
Korean J Ophthalmol 2013 Apr;27(2):126-9. Epub 2013 Feb 27 doi: 10.3341/kjo.2013.27.2.126. PMID: 23543280Free PMC Article
Nasolacrimal duct oncocytoma: an unusual cause of chronic epiphora.
Delas B, Bertrand M, Babin E, François A, Marie JP, Dehesdin D, Choussy O
Ear Nose Throat J 2010 Mar;89(3):132-9. PMID: 20229479

Recent systematic reviews

A systematic review of sinonasal oncocytomas and oncocytic carcinomas: Diagnosis, management, and technical considerations.
Hodzic Z, Rowan NR, Kashiwazaki R, Willson TJ, Wang EW, Lee SE
Int Forum Allergy Rhinol 2017 May;7(5):514-524. Epub 2017 Jan 16 doi: 10.1002/alr.21902. PMID: 28092140
Nasolacrimal duct tumours in the era of endoscopic dacryocystorhinostomy: literature review.
Tanweer F, Mahkamova K, Harkness P
J Laryngol Otol 2013 Jul;127(7):670-5. Epub 2013 Jun 12 doi: 10.1017/S0022215113001163. PMID: 23756574

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...