U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Microsatellite Stable Colon Carcinoma

MedGen UID:
1791055
Concept ID:
C5554614
Neoplastic Process

Definition

Colon carcinoma characterized by the absence of microsatellite instability. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMicrosatellite Stable Colon Carcinoma

Professional guidelines

PubMed

Margalit O, Lieberman S, Redinsky I, Halparin S, Honig N, Raskin S, Ben-Ayun M, Shacham-Shmueli E, Halpern N, Urban D, Ackerstein A, Shulman K, Ben-Ami E, Semenisty V, Purim O, Yarom N, Golan T, Boursi B, Appel S, Symon Z, Berger R, Mauro D, Krieg AM, Lawrence YR
Clin Colorectal Cancer 2023 Dec;22(4):442-449.e1. Epub 2023 Aug 9 doi: 10.1016/j.clcc.2023.08.004. PMID: 37657954
Cao L, Zhang S, Yao D, Ba Y, Weng Q, Yang J, Zhang H, Ren Y
Aging (Albany NY) 2023 Jul 21;15(14):7098-7123. doi: 10.18632/aging.204894. PMID: 37480572Free PMC Article
Murakami T, Sakamoto N, Nagahara A
J Gastroenterol Hepatol 2019 Oct;34(10):1685-1695. Epub 2019 Jun 30 doi: 10.1111/jgh.14752. PMID: 31158302

Recent clinical studies

Etiology

Topal U, Gülcan P, Yüksel S, Teke Z, Bektaş H, Duman M
Eur Rev Med Pharmacol Sci 2023 Oct;27(20):9793-9800. doi: 10.26355/eurrev_202310_34154. PMID: 37916344
Hirsch D, Hardt J, Sauer C, Heselmeyer-Hadded K, Witt SH, Kienle P, Ried T, Gaiser T
Mod Pathol 2021 Jun;34(6):1153-1166. Epub 2020 Dec 14 doi: 10.1038/s41379-020-00722-5. PMID: 33318582Free PMC Article
Sukhokanjanachusak K, Pongpaibul A, Nimmannit A, Akewanlop C, Korphaisarn K
J Adolesc Young Adult Oncol 2021 Oct;10(5):573-580. Epub 2020 Oct 20 doi: 10.1089/jayao.2020.0144. PMID: 33085547
Murakami T, Sakamoto N, Nagahara A
J Gastroenterol Hepatol 2019 Oct;34(10):1685-1695. Epub 2019 Jun 30 doi: 10.1111/jgh.14752. PMID: 31158302
Liu Y, Sethi NS, Hinoue T, Schneider BG, Cherniack AD, Sanchez-Vega F, Seoane JA, Farshidfar F, Bowlby R, Islam M, Kim J, Chatila W, Akbani R, Kanchi RS, Rabkin CS, Willis JE, Wang KK, McCall SJ, Mishra L, Ojesina AI, Bullman S, Pedamallu CS, Lazar AJ, Sakai R; Cancer Genome Atlas Research Network, Thorsson V, Bass AJ, Laird PW
Cancer Cell 2018 Apr 9;33(4):721-735.e8. Epub 2018 Apr 2 doi: 10.1016/j.ccell.2018.03.010. PMID: 29622466Free PMC Article

Diagnosis

Topal U, Gülcan P, Yüksel S, Teke Z, Bektaş H, Duman M
Eur Rev Med Pharmacol Sci 2023 Oct;27(20):9793-9800. doi: 10.26355/eurrev_202310_34154. PMID: 37916344
Jacobson RA, Bhama AR
Dis Colon Rectum 2021 Jul 1;64(7):777-780. doi: 10.1097/DCR.0000000000002103. PMID: 33872286
Hirsch D, Hardt J, Sauer C, Heselmeyer-Hadded K, Witt SH, Kienle P, Ried T, Gaiser T
Mod Pathol 2021 Jun;34(6):1153-1166. Epub 2020 Dec 14 doi: 10.1038/s41379-020-00722-5. PMID: 33318582Free PMC Article
Murakami T, Sakamoto N, Nagahara A
J Gastroenterol Hepatol 2019 Oct;34(10):1685-1695. Epub 2019 Jun 30 doi: 10.1111/jgh.14752. PMID: 31158302
Affolter K, Samowitz W, Tripp S, Bronner MP
Genes Chromosomes Cancer 2013 Aug;52(8):748-52. Epub 2013 May 7 doi: 10.1002/gcc.22070. PMID: 23650027

Therapy

Colombo A, Concetta PM, Gebbia V, Sambataro D, Scandurra G, Valerio MR
In Vivo 2025 Jan-Feb;39(1):25-36. doi: 10.21873/invivo.13802. PMID: 39740863Free PMC Article
Margalit O, Lieberman S, Redinsky I, Halparin S, Honig N, Raskin S, Ben-Ayun M, Shacham-Shmueli E, Halpern N, Urban D, Ackerstein A, Shulman K, Ben-Ami E, Semenisty V, Purim O, Yarom N, Golan T, Boursi B, Appel S, Symon Z, Berger R, Mauro D, Krieg AM, Lawrence YR
Clin Colorectal Cancer 2023 Dec;22(4):442-449.e1. Epub 2023 Aug 9 doi: 10.1016/j.clcc.2023.08.004. PMID: 37657954
Cui Z, Wang Q, Deng M, Meng E, Liu S, Niu B, Han Q
Immunotherapy 2023 Feb;15(3):127-133. Epub 2023 Feb 1 doi: 10.2217/imt-2022-0058. PMID: 36722149
Bohaumilitzky L, Kluck K, Hüneburg R, Gallon R, Nattermann J, Kirchner M, Kristiansen G, Hommerding O, Pfuderer PL, Wagner L, Echterdiek F, Kösegi S, Müller N, Fischer K, Nelius N, Hartog B, Borthwick G, Busch E, Haag GM, Bläker H, Möslein G, von Knebel Doeberitz M, Seppälä TT, Ahtiainen M, Mecklin JP, Bishop DT, Burn J, Stenzinger A, Budczies J, Kloor M, Ahadova A
Gastroenterology 2022 Mar;162(3):907-919.e10. Epub 2021 Dec 2 doi: 10.1053/j.gastro.2021.11.029. PMID: 34863788
Murakami T, Sakamoto N, Nagahara A
J Gastroenterol Hepatol 2019 Oct;34(10):1685-1695. Epub 2019 Jun 30 doi: 10.1111/jgh.14752. PMID: 31158302

Prognosis

Topal U, Gülcan P, Yüksel S, Teke Z, Bektaş H, Duman M
Eur Rev Med Pharmacol Sci 2023 Oct;27(20):9793-9800. doi: 10.26355/eurrev_202310_34154. PMID: 37916344
Gutierrez C, Ogino S, Meyerhardt JA, Iorgulescu JB
JCO Precis Oncol 2023 Jan;7:e2200179. doi: 10.1200/PO.22.00179. PMID: 36716414Free PMC Article
Cavallaro PM, Stafford C, Cauley CE, Berger DL, Bordeianou L, Kunitake H, Francone T, Ricciardi R
Dis Colon Rectum 2021 May;64(5):545-554. doi: 10.1097/DCR.0000000000001914. PMID: 33939386Free PMC Article
Sukhokanjanachusak K, Pongpaibul A, Nimmannit A, Akewanlop C, Korphaisarn K
J Adolesc Young Adult Oncol 2021 Oct;10(5):573-580. Epub 2020 Oct 20 doi: 10.1089/jayao.2020.0144. PMID: 33085547
Hogan J, DeJulius K, Liu X, Coffey JC, Kalady MF
Gene 2015 Oct 1;570(1):36-43. Epub 2015 Feb 20 doi: 10.1016/j.gene.2015.02.057. PMID: 25704535

Clinical prediction guides

Topal U, Gülcan P, Yüksel S, Teke Z, Bektaş H, Duman M
Eur Rev Med Pharmacol Sci 2023 Oct;27(20):9793-9800. doi: 10.26355/eurrev_202310_34154. PMID: 37916344
Arora S, Adhikari N, Rathi AK, Singh K, Sakhuja P
J Cancer Res Ther 2022 Apr-Jun;18(3):656-660. doi: 10.4103/jcrt.jcrt_423_21. PMID: 35900537
Mäki-Nevala S, Ukwattage S, Wirta EV, Ahtiainen M, Ristimäki A, Seppälä TT, Lepistö A, Mecklin JP, Peltomäki P
Biomolecules 2021 Sep 30;11(10) doi: 10.3390/biom11101440. PMID: 34680073Free PMC Article
Hogan J, DeJulius K, Liu X, Coffey JC, Kalady MF
Gene 2015 Oct 1;570(1):36-43. Epub 2015 Feb 20 doi: 10.1016/j.gene.2015.02.057. PMID: 25704535
Affolter K, Samowitz W, Tripp S, Bronner MP
Genes Chromosomes Cancer 2013 Aug;52(8):748-52. Epub 2013 May 7 doi: 10.1002/gcc.22070. PMID: 23650027

Recent systematic reviews

Nejadtaghi M, Jafari H, Farrokhi E, Samani KG
Curr Probl Cancer 2017 Nov-Dec;41(6):388-397. Epub 2017 Oct 18 doi: 10.1016/j.currproblcancer.2017.10.002. PMID: 29096939

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...