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Urothelial Carcinoma, High Grade

MedGen UID:
1792937
•Concept ID:
C5556496
•
Neoplastic Process
Synonyms: High Grade Urothelial Carcinoma; High-Grade Urothelial Carcinoma

Definition

Urothelial carcinoma characterized by the presence of neoplastic epithelial cells with high grade features. [from NCI]

Professional guidelines

PubMed

"Collecting duct carcinoma of the kidney: diagnosis and implications for management".
Cabanillas G, Montoya-Cerrillo D, Kryvenko ON, Pal SK, Arias-Stella JA 3rd
Urol Oncol 2022 Dec;40(12):525-536. Epub 2021 Jun 8 doi: 10.1016/j.urolonc.2021.04.041. PMID: 34116936
Next-generation sequencing-based molecular characterization of primary urinary bladder adenocarcinoma.
Roy S, Pradhan D, Ernst WL, Mercurio S, Najjar Y, Parikh R, Parwani AV, Pai RK, Dhir R, Nikiforova MN
Mod Pathol 2017 Aug;30(8):1133-1143. Epub 2017 May 26 doi: 10.1038/modpathol.2017.33. PMID: 28548125
Endoscopic Treatment of Upper Tract Urothelial Carcinoma.
Verges DP, Lallas CD, Hubosky SG, Bagley DH Jr
Curr Urol Rep 2017 Apr;18(4):31. doi: 10.1007/s11934-017-0675-x. PMID: 28251485

Recent clinical studies

Etiology

Expression of miR-100 as a novel ancillary non-invasive biomarker for early detection of bladder carcinoma.
Qureshi A, Fahim A, Kazi N, Farsi Kazi SA, Nadeem F
J Pak Med Assoc 2018 May;68(5):759-763. PMID: 29885177
Aurora-A/STK-15 is a predictive factor for recurrent behaviour in non-invasive bladder carcinoma: a study of 128 cases of non-invasive neoplasms.
Compérat E, Camparo P, Haus R, Chartier-Kastler E, Radenen B, Richard F, Capron F, Paradis V
Virchows Arch 2007 Apr;450(4):419-24. Epub 2007 Feb 28 doi: 10.1007/s00428-007-0383-x. PMID: 17333265
Immunohistochemical expression of p63, p53 and MIB-1 in urinary bladder carcinoma. A tissue microarray study of 158 cases.
Compérat E, Camparo P, Haus R, Chartier-Kastler E, Bart S, Delcourt A, Houlgatte A, François R, Capron F, Vieillefond A
Virchows Arch 2006 Mar;448(3):319-24. Epub 2005 Nov 8 doi: 10.1007/s00428-005-0092-2. PMID: 16283378

Diagnosis

Objective Evaluation of Gaze Location Patterns Using Eye Tracking During Cystoscopy and Artificial Intelligence-Assisted Lesion Detection.
Ikeda A, Izumi K, Katori K, Nosato H, Kobayashi K, Suzuki S, Kandori S, Sanuki M, Ochiai Y, Nishiyama H
J Endourol 2024 Aug;38(8):865-870. Epub 2024 Apr 16 doi: 10.1089/end.2023.0699. PMID: 38526374
Expression of miR-100 as a novel ancillary non-invasive biomarker for early detection of bladder carcinoma.
Qureshi A, Fahim A, Kazi N, Farsi Kazi SA, Nadeem F
J Pak Med Assoc 2018 May;68(5):759-763. PMID: 29885177
Primary multiple clear cell variant urothelial carcinomas of urinary bladder: a rare case report.
Zhang Y, Huang J, Feng H, Tang Y
Int J Clin Exp Pathol 2014;7(6):3385-8. Epub 2014 May 15 PMID: 25031765Free PMC Article
Aurora-A/STK-15 is a predictive factor for recurrent behaviour in non-invasive bladder carcinoma: a study of 128 cases of non-invasive neoplasms.
Compérat E, Camparo P, Haus R, Chartier-Kastler E, Radenen B, Richard F, Capron F, Paradis V
Virchows Arch 2007 Apr;450(4):419-24. Epub 2007 Feb 28 doi: 10.1007/s00428-007-0383-x. PMID: 17333265

Prognosis

Aurora-A/STK-15 is a predictive factor for recurrent behaviour in non-invasive bladder carcinoma: a study of 128 cases of non-invasive neoplasms.
Compérat E, Camparo P, Haus R, Chartier-Kastler E, Radenen B, Richard F, Capron F, Paradis V
Virchows Arch 2007 Apr;450(4):419-24. Epub 2007 Feb 28 doi: 10.1007/s00428-007-0383-x. PMID: 17333265
Immunohistochemical expression of p63, p53 and MIB-1 in urinary bladder carcinoma. A tissue microarray study of 158 cases.
Compérat E, Camparo P, Haus R, Chartier-Kastler E, Bart S, Delcourt A, Houlgatte A, François R, Capron F, Vieillefond A
Virchows Arch 2006 Mar;448(3):319-24. Epub 2005 Nov 8 doi: 10.1007/s00428-005-0092-2. PMID: 16283378

Clinical prediction guides

Objective Evaluation of Gaze Location Patterns Using Eye Tracking During Cystoscopy and Artificial Intelligence-Assisted Lesion Detection.
Ikeda A, Izumi K, Katori K, Nosato H, Kobayashi K, Suzuki S, Kandori S, Sanuki M, Ochiai Y, Nishiyama H
J Endourol 2024 Aug;38(8):865-870. Epub 2024 Apr 16 doi: 10.1089/end.2023.0699. PMID: 38526374
Aurora-A/STK-15 is a predictive factor for recurrent behaviour in non-invasive bladder carcinoma: a study of 128 cases of non-invasive neoplasms.
Compérat E, Camparo P, Haus R, Chartier-Kastler E, Radenen B, Richard F, Capron F, Paradis V
Virchows Arch 2007 Apr;450(4):419-24. Epub 2007 Feb 28 doi: 10.1007/s00428-007-0383-x. PMID: 17333265
Immunohistochemical expression of p63, p53 and MIB-1 in urinary bladder carcinoma. A tissue microarray study of 158 cases.
Compérat E, Camparo P, Haus R, Chartier-Kastler E, Bart S, Delcourt A, Houlgatte A, François R, Capron F, Vieillefond A
Virchows Arch 2006 Mar;448(3):319-24. Epub 2005 Nov 8 doi: 10.1007/s00428-005-0092-2. PMID: 16283378

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