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Erythema of the Oropharyngeal Mucosa

MedGen UID:
1793004
•Concept ID:
C5556563
•
Sign or Symptom

Definition

Erythema of the mucus membranes lining the part of the pharynx located between the soft palate and the upper portion of the epiglottis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVErythema of the Oropharyngeal Mucosa

Professional guidelines

PubMed

Radiotherapy in the management of epidemic Kaposi's sarcoma.
Piedbois P, Frikha H, Martin L, Levy E, Haddad E, Le Bourgeois JP
Int J Radiat Oncol Biol Phys 1994 Dec 1;30(5):1207-11. doi: 10.1016/0360-3016(94)90330-1. PMID: 7525519

Recent clinical studies

Etiology

Toxic epidermal necrolysis: management strategies in burns units.
Escuredo IM, Weisz LC, Manau JV, Soto JBA, García JG
J Wound Care 2024 Dec 2;33(12):942-949. doi: 10.12968/jowc.2021.0063. PMID: 39630547
Epidermolysis Bullosa Oropharyngeal Severity (EBOS) score: a multicenter development and reliability assessment.
Fortuna G, Chainani-Wu N, Lozada-Nur F, Aria M, Cepeda-Valdes R, Pollio A, Marinkovich MP, Martinez-Salazar AE, Mignogna MD, Bruckner AL, Salas-Alanís JC
J Am Acad Dermatol 2013 Jan;68(1):83-92. Epub 2012 May 8 doi: 10.1016/j.jaad.2012.04.009. PMID: 22575158
Correlation between viral load, plasma levels of CD4 - CD8 T lymphocytes and AIDS-related oral diseases: a multicentre study on 30 HIV+ children in the HAART era.
Nesti M, Carli E, Giaquinto C, Rampon O, Nastasio S, Giuca MR
J Biol Regul Homeost Agents 2012 Jul-Sep;26(3):527-37. PMID: 23034272
Aggressive simultaneous radiochemotherapy with cisplatin and paclitaxel in combination with accelerated hyperfractionated radiotherapy in locally advanced head and neck tumors. Results of a phase I-II trial.
Kuhnt T, Becker A, Pigorsch S, Pelz T, Bloching M, Passmann M, Lotterer E, Hänsgen G, Dunst J
Strahlenther Onkol 2003 Oct;179(10):673-81. doi: 10.1007/s00066-003-1106-0. PMID: 14566475
Oropharyngeal manifestations of lepidopterism.
Lee D, Pitetti RD, Casselbrant ML
Arch Otolaryngol Head Neck Surg 1999 Jan;125(1):50-2. doi: 10.1001/archotol.125.1.50. PMID: 9932587

Diagnosis

Pterygoid Hamulus Bursitis: A Rare Intra-Oral Pain Syndrome.
Thukral H, Nagori SA, Rawat A, Jose A
J Craniofac Surg 2019 Oct;30(7):e643-e645. doi: 10.1097/SCS.0000000000005700. PMID: 31233003
Toxic Epidermal Necrolysis with Gastrointestinal Involvement: A Case Report and Review of the Literature.
Brown CS, Defazio JR, An G, O'Connor A, Whitcomb E, Hart J, Gottlieb LJ
J Burn Care Res 2017 Jan/Feb;38(1):e450-e455. doi: 10.1097/BCR.0000000000000336. PMID: 27058583
Acute mucosal radiation reactions in patients with head and neck cancer. Patterns of mucosal healing on the basis of daily examinations.
Wygoda A, Składowski K, Rutkowski T, Hutnik M, Goleń M, Pilecki B, Przeorek W, Lukaszczyk-Wideł B
Strahlenther Onkol 2012 Aug;188(8):686-91. Epub 2012 Jun 24 doi: 10.1007/s00066-012-0146-8. PMID: 22729281
Nikolsky's sign on the gingival mucosa: a clinical tool for oral health practitioners.
Mignogna MD, Fortuna G, Leuci S, Ruoppo E, Marasca F, Matarasso S
J Periodontol 2008 Dec;79(12):2241-6. doi: 10.1902/jop.2008.080217. PMID: 19053912
Oropharyngeal manifestations of lepidopterism.
Lee D, Pitetti RD, Casselbrant ML
Arch Otolaryngol Head Neck Surg 1999 Jan;125(1):50-2. doi: 10.1001/archotol.125.1.50. PMID: 9932587

Therapy

Toxic Epidermal Necrolysis with Gastrointestinal Involvement: A Case Report and Review of the Literature.
Brown CS, Defazio JR, An G, O'Connor A, Whitcomb E, Hart J, Gottlieb LJ
J Burn Care Res 2017 Jan/Feb;38(1):e450-e455. doi: 10.1097/BCR.0000000000000336. PMID: 27058583
Correlation between viral load, plasma levels of CD4 - CD8 T lymphocytes and AIDS-related oral diseases: a multicentre study on 30 HIV+ children in the HAART era.
Nesti M, Carli E, Giaquinto C, Rampon O, Nastasio S, Giuca MR
J Biol Regul Homeost Agents 2012 Jul-Sep;26(3):527-37. PMID: 23034272
Late effects of post-high-dose-rate brachytherapy for oropharyngeal carcinoma: are they severer than post-low-dose-rate?
Nose T, Peiffert D, Lapeyre M, Hoffstetter S, Koizumi M, Nishiyama K
Strahlenther Onkol 2004 Dec;180(12):776-82. doi: 10.1007/s00066-004-1270-x. PMID: 15592697
Aggressive simultaneous radiochemotherapy with cisplatin and paclitaxel in combination with accelerated hyperfractionated radiotherapy in locally advanced head and neck tumors. Results of a phase I-II trial.
Kuhnt T, Becker A, Pigorsch S, Pelz T, Bloching M, Passmann M, Lotterer E, Hänsgen G, Dunst J
Strahlenther Onkol 2003 Oct;179(10):673-81. doi: 10.1007/s00066-003-1106-0. PMID: 14566475
Irradiation scheme using three daily fractions in the radiation therapy of pharyngeal and oral carcinomas.
Durkovský J, Jancina J, Siracká E, Krajci M
Neoplasma 1984;31(2):213-22. PMID: 6717690

Prognosis

Toxic epidermal necrolysis: management strategies in burns units.
Escuredo IM, Weisz LC, Manau JV, Soto JBA, García JG
J Wound Care 2024 Dec 2;33(12):942-949. doi: 10.12968/jowc.2021.0063. PMID: 39630547
Toxic Epidermal Necrolysis with Gastrointestinal Involvement: A Case Report and Review of the Literature.
Brown CS, Defazio JR, An G, O'Connor A, Whitcomb E, Hart J, Gottlieb LJ
J Burn Care Res 2017 Jan/Feb;38(1):e450-e455. doi: 10.1097/BCR.0000000000000336. PMID: 27058583
Acute mucosal radiation reactions in patients with head and neck cancer. Patterns of mucosal healing on the basis of daily examinations.
Wygoda A, Składowski K, Rutkowski T, Hutnik M, Goleń M, Pilecki B, Przeorek W, Lukaszczyk-Wideł B
Strahlenther Onkol 2012 Aug;188(8):686-91. Epub 2012 Jun 24 doi: 10.1007/s00066-012-0146-8. PMID: 22729281
Aggressive simultaneous radiochemotherapy with cisplatin and paclitaxel in combination with accelerated hyperfractionated radiotherapy in locally advanced head and neck tumors. Results of a phase I-II trial.
Kuhnt T, Becker A, Pigorsch S, Pelz T, Bloching M, Passmann M, Lotterer E, Hänsgen G, Dunst J
Strahlenther Onkol 2003 Oct;179(10):673-81. doi: 10.1007/s00066-003-1106-0. PMID: 14566475
Radiotherapy in the management of epidemic Kaposi's sarcoma.
Piedbois P, Frikha H, Martin L, Levy E, Haddad E, Le Bourgeois JP
Int J Radiat Oncol Biol Phys 1994 Dec 1;30(5):1207-11. doi: 10.1016/0360-3016(94)90330-1. PMID: 7525519

Clinical prediction guides

Toxic epidermal necrolysis: management strategies in burns units.
Escuredo IM, Weisz LC, Manau JV, Soto JBA, García JG
J Wound Care 2024 Dec 2;33(12):942-949. doi: 10.12968/jowc.2021.0063. PMID: 39630547
Epidermolysis Bullosa Oropharyngeal Severity (EBOS) score: a multicenter development and reliability assessment.
Fortuna G, Chainani-Wu N, Lozada-Nur F, Aria M, Cepeda-Valdes R, Pollio A, Marinkovich MP, Martinez-Salazar AE, Mignogna MD, Bruckner AL, Salas-Alanís JC
J Am Acad Dermatol 2013 Jan;68(1):83-92. Epub 2012 May 8 doi: 10.1016/j.jaad.2012.04.009. PMID: 22575158
Late effects of post-high-dose-rate brachytherapy for oropharyngeal carcinoma: are they severer than post-low-dose-rate?
Nose T, Peiffert D, Lapeyre M, Hoffstetter S, Koizumi M, Nishiyama K
Strahlenther Onkol 2004 Dec;180(12):776-82. doi: 10.1007/s00066-004-1270-x. PMID: 15592697
The correlation between epidermal growth factor levels in saliva and the severity of oral mucositis during oropharyngeal radiation therapy.
Epstein JB, Gorsky M, Guglietta A, Le N, Sonis ST
Cancer 2000 Dec 1;89(11):2258-65. doi: 10.1002/1097-0142(20001201)89:11<2258::aid-cncr14>3.0.co;2-z. PMID: 11147596
Oropharyngeal manifestations of lepidopterism.
Lee D, Pitetti RD, Casselbrant ML
Arch Otolaryngol Head Neck Surg 1999 Jan;125(1):50-2. doi: 10.1001/archotol.125.1.50. PMID: 9932587

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