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Cranial Nerve II Palsy

MedGen UID:
1793216
•Concept ID:
C5556775
•
Disease or Syndrome
Synonyms: Optic Nerve Palsy; Second Cranial Nerve Palsy

Definition

Partial or complete paralysis of the optic nerve. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCranial Nerve II Palsy

Professional guidelines

PubMed

Neurobrucellosis: laboratory features, clinical characteristics, antibiotic treatment, and clinical outcomes of 21 patients.
Zhuang W, He T, Tuerheng J, He G, Wang BL, Yang YH, Zhang L, Dong XZ, Xi SY
BMC Infect Dis 2024 May 10;24(1):485. doi: 10.1186/s12879-024-09308-x. PMID: 38730327Free PMC Article
Diagnosis of idiopathic intracranial hypertension: A proposal for evidence-based diagnostic criteria.
Korsbæk JJ, Jensen RH, Høgedal L, Molander LD, Hagen SM, Beier D
Cephalalgia 2023 Mar;43(3):3331024231152795. doi: 10.1177/03331024231152795. PMID: 36786317
Diagnosis and treatment of paralysis of the larynx and pharynx.
Dedo HH
Proc R Soc Med 1975 Oct;68(10):639-41. PMID: 1208513Free PMC Article

Recent clinical studies

Etiology

Post-surgical complications of a Shamblin Type II carotid body tumor, a case study.
Gowans C, Treat-Jacobson D
J Vasc Nurs 2023 Dec;41(4):245-247. doi: 10.1016/j.jvn.2023.11.001. PMID: 38072580
Cilta-cel or Standard Care in Lenalidomide-Refractory Multiple Myeloma.
San-Miguel J, Dhakal B, Yong K, Spencer A, Anguille S, Mateos MV, Fernández de Larrea C, Martínez-López J, Moreau P, Touzeau C, Leleu X, Avivi I, Cavo M, Ishida T, Kim SJ, Roeloffzen W, van de Donk NWCJ, Dytfeld D, Sidana S, Costa LJ, Oriol A, Popat R, Khan AM, Cohen YC, Ho PJ, Griffin J, Lendvai N, Lonardi C, Slaughter A, Schecter JM, Jackson CC, Connors K, Li K, Zudaire E, Chen D, Gilbert J, Yeh TM, Nagle S, Florendo E, Pacaud L, Patel N, Harrison SJ, Einsele H
N Engl J Med 2023 Jul 27;389(4):335-347. Epub 2023 Jun 5 doi: 10.1056/NEJMoa2303379. PMID: 37272512
Ocular manifestations of COVID-19 in the pediatric age group.
Alnahdi MA, Alkharashi M
Eur J Ophthalmol 2023 Jan;33(1):21-28. Epub 2022 Jul 27 doi: 10.1177/11206721221116210. PMID: 35898182Free PMC Article
Parasellar Meningiomas.
Graillon T, Regis J, Barlier A, Brue T, Dufour H, Buchfelder M
Neuroendocrinology 2020;110(9-10):780-796. Epub 2020 Jun 3 doi: 10.1159/000509090. PMID: 32492684
The ocular manifestations of Lyme disease.
Zaidman GW
Int Ophthalmol Clin 1997 Spring;37(2):13-28. doi: 10.1097/00004397-199703720-00003. PMID: 9269595

Diagnosis

Parasellar Meningiomas.
Graillon T, Regis J, Barlier A, Brue T, Dufour H, Buchfelder M
Neuroendocrinology 2020;110(9-10):780-796. Epub 2020 Jun 3 doi: 10.1159/000509090. PMID: 32492684
MOG antibody-associated encephalomyelitis/encephalitis.
Salama S, Khan M, Pardo S, Izbudak I, Levy M
Mult Scler 2019 Oct;25(11):1427-1433. Epub 2019 Mar 25 doi: 10.1177/1352458519837705. PMID: 30907249Free PMC Article
A Bloody Mess!
Brodsky MC, Biousse V
Surv Ophthalmol 2018 Mar-Apr;63(2):268-274. Epub 2017 May 18 doi: 10.1016/j.survophthal.2017.05.004. PMID: 28527856
Neuro-ophthalmology.
Thompson HS
Arch Ophthalmol 1971 Oct;86(4):462-82. doi: 10.1001/archopht.1971.01000010464021. PMID: 4329269
Neuro-ophthalmology.
Knox DL
Arch Ophthalmol 1968 Dec;80(6):791-807. doi: 10.1001/archopht.1968.00980050793021. PMID: 4301976

Therapy

Cilta-cel or Standard Care in Lenalidomide-Refractory Multiple Myeloma.
San-Miguel J, Dhakal B, Yong K, Spencer A, Anguille S, Mateos MV, Fernández de Larrea C, Martínez-López J, Moreau P, Touzeau C, Leleu X, Avivi I, Cavo M, Ishida T, Kim SJ, Roeloffzen W, van de Donk NWCJ, Dytfeld D, Sidana S, Costa LJ, Oriol A, Popat R, Khan AM, Cohen YC, Ho PJ, Griffin J, Lendvai N, Lonardi C, Slaughter A, Schecter JM, Jackson CC, Connors K, Li K, Zudaire E, Chen D, Gilbert J, Yeh TM, Nagle S, Florendo E, Pacaud L, Patel N, Harrison SJ, Einsele H
N Engl J Med 2023 Jul 27;389(4):335-347. Epub 2023 Jun 5 doi: 10.1056/NEJMoa2303379. PMID: 37272512
COVID-19 presenting with ophthalmoparesis from cranial nerve palsy.
Dinkin M, Gao V, Kahan J, Bobker S, Simonetto M, Wechsler P, Harpe J, Greer C, Mints G, Salama G, Tsiouris AJ, Leifer D
Neurology 2020 Aug 4;95(5):221-223. Epub 2020 May 1 doi: 10.1212/WNL.0000000000009700. PMID: 32358218
MOG antibody-associated encephalomyelitis/encephalitis.
Salama S, Khan M, Pardo S, Izbudak I, Levy M
Mult Scler 2019 Oct;25(11):1427-1433. Epub 2019 Mar 25 doi: 10.1177/1352458519837705. PMID: 30907249Free PMC Article
A baby with a lot of nerve.
Ramkumar HL, Verma R, Crow J, Robbins S, Granet DB, Sheldon CA, Henretig FM, Liu GT
Surv Ophthalmol 2016 Jul-Aug;61(4):506-11. Epub 2015 Nov 30 doi: 10.1016/j.survophthal.2015.11.007. PMID: 26656927
Neuro-ophthalmology.
Thompson HS
Arch Ophthalmol 1971 Oct;86(4):462-82. doi: 10.1001/archopht.1971.01000010464021. PMID: 4329269

Prognosis

Neuro-ophthalmologic complications of coronavirus disease 2019 (COVID-19).
Gold DM, Galetta SL
Neurosci Lett 2021 Jan 18;742:135531. Epub 2020 Nov 25 doi: 10.1016/j.neulet.2020.135531. PMID: 33248158Free PMC Article
Ocular problems in early stages of multiple sclerosis.
Roodhooft JM
Bull Soc Belge Ophtalmol 2009;(313):65-8. PMID: 20108574
Brown-Vialetto-Van Laere syndrome.
Sathasivam S
Orphanet J Rare Dis 2008 Apr 17;3:9. doi: 10.1186/1750-1172-3-9. PMID: 18416855Free PMC Article
Neuro-ophthalmic manifestations of hemangiopericytoma.
Lee AG, Eggenberger E, Galetta S, Kerrison J, Miller NR, Kirby P, Wall M, Hitchon P, Kardon RH
Semin Ophthalmol 2004 Sep-Dec;19(3-4):95-100. doi: 10.1080/08820530490882445. PMID: 15590545
The ocular manifestations of Lyme disease.
Zaidman GW
Int Ophthalmol Clin 1997 Spring;37(2):13-28. doi: 10.1097/00004397-199703720-00003. PMID: 9269595

Clinical prediction guides

COVID-19 and Eye: A Review of Ophthalmic Manifestations of COVID-19.
Sen M, Honavar SG, Sharma N, Sachdev MS
Indian J Ophthalmol 2021 Mar;69(3):488-509. doi: 10.4103/ijo.IJO_297_21. PMID: 33595463Free PMC Article
Retinal Manifestations of Idiopathic Intracranial Hypertension.
Nichani P, Micieli JA
Ophthalmol Retina 2021 May;5(5):429-437. Epub 2020 Aug 26 doi: 10.1016/j.oret.2020.08.016. PMID: 32860958
Parasellar Meningiomas.
Graillon T, Regis J, Barlier A, Brue T, Dufour H, Buchfelder M
Neuroendocrinology 2020;110(9-10):780-796. Epub 2020 Jun 3 doi: 10.1159/000509090. PMID: 32492684
The use of mechanical thrombectomy in the treatment of basilar artery occlusion--case report.
Knap D, Honkowicz M, Kirmes T, Koroński M, Kysiak M, Bukański M, Sieroń D, Dymon I, Baron J
Neurol Neurochir Pol 2015;49(5):332-8. Epub 2015 Jul 29 doi: 10.1016/j.pjnns.2015.07.004. PMID: 26377986
Ocular problems in early stages of multiple sclerosis.
Roodhooft JM
Bull Soc Belge Ophtalmol 2009;(313):65-8. PMID: 20108574

Recent systematic reviews

Improvement in cranial nerve palsies following treatment of intracranial aneurysms with flow diverters: Institutional outcomes, systematic review and study-level meta-analysis.
Sujijantarat N, Antonios JP, Renedo D, Koo AB, Haynes JO, Fathima B, Jiang JW, Hengartner AC, Shekhar AH, Amllay A, Nowicki KW, Hebert RM, Gilmore EJ, Sheth KN, King JT Jr, Matouk CC
Clin Neurol Neurosurg 2024 Nov;246:108555. Epub 2024 Sep 22 doi: 10.1016/j.clineuro.2024.108555. PMID: 39357321
Immune checkpoint inhibitors-associated cranial nerves involvement: a systematic literature review on 136 patients.
Pichon S, Aigrain P, Lacombe C, Lemarchant B, Ledoult E, Koether V, Leurs A, Zebian G, Launay D, Gachet B, Levy C
J Neurol 2024 Oct;271(10):6514-6525. Epub 2024 Sep 3 doi: 10.1007/s00415-024-12660-2. PMID: 39225744Free PMC Article
Neuro-Ophthalmological Complications of the COVID-19 Vaccines: A Systematic Review.
Lotan I, Lydston M, Levy M
J Neuroophthalmol 2022 Jun 1;42(2):154-162. Epub 2022 Mar 25 doi: 10.1097/WNO.0000000000001537. PMID: 35427282
Efficacy of mycophenolate mofetil in the treatment of neuromyelitis optica spectrum disorders: An update systematic review and meta -analysis.
Wang Y, Ma J, Chang H, Zhang X, Yin L
Mult Scler Relat Disord 2021 Oct;55:103181. Epub 2021 Jul 31 doi: 10.1016/j.msard.2021.103181. PMID: 34365314
Efficacy of rituximab in the treatment of neuromyelitis optica spectrum disorders: An update systematic review and meta -analysis.
Wang Y, Chang H, Zhang X, Yin L
Mult Scler Relat Disord 2021 May;50:102843. Epub 2021 Feb 13 doi: 10.1016/j.msard.2021.102843. PMID: 33609924

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