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Hybrid Salivary Gland Tumor

MedGen UID:
1793275
Concept ID:
C5556834
Neoplastic Process
Synonym: Hybrid Salivary Gland Neoplasm

Definition

A rare neoplasm that arises from the salivary gland and consists of at least two histologically distinct types of tumor within the same topographic location. The tumor components can be either benign or malignant. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHybrid Salivary Gland Tumor

Professional guidelines

PubMed

Luk PP, Selinger CI, Cooper WA, Mahar A, Palme CE, O'Toole SA, Clark JR, Gupta R
Head Neck Pathol 2019 Sep;13(3):397-414. Epub 2018 Nov 22 doi: 10.1007/s12105-018-0988-1. PMID: 30467669Free PMC Article
Luk PP, Selinger CI, Eviston TJ, Lum T, Yu B, O'Toole SA, Clark JR, Gupta R
Pathology 2015 Dec;47(7):659-66. doi: 10.1097/PAT.0000000000000322. PMID: 26517645
Perissinotti AJ, Lee Pierce M, Pace MB, El-Naggar A, Kies MS, Kupferman M
Anticancer Res 2013 Jun;33(6):2587-91. PMID: 23749912

Recent clinical studies

Etiology

Venkat S, Fitzpatrick S, Drew PA, Bhattacharyya I, Cohen DM, Islam MN
Head Neck Pathol 2021 Sep;15(3):893-904. Epub 2021 Mar 3 doi: 10.1007/s12105-021-01310-y. PMID: 33660147Free PMC Article
Majewska H, Gorczyński A, Czapiewski P, Menon R, Mueller J, Lakis S, Heuckmann JM, Laco J, Gupta R, Andreasen S, Stodulski D, Iliszko M, Dziadziuszko R, Jassem J, Heukamp LC, Biernat W
Virchows Arch 2021 May;478(5):933-941. Epub 2020 Nov 25 doi: 10.1007/s00428-020-02971-w. PMID: 33237469Free PMC Article
Griffith CC, Siddiqui MT, Schmitt AC
Diagn Cytopathol 2017 Sep;45(9):808-819. Epub 2017 Apr 14 doi: 10.1002/dc.23715. PMID: 28411379
Wenig BM
Semin Diagn Pathol 2015 Jan;32(1):74-86. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.004. PMID: 25804344
Seethala RR
Adv Anat Pathol 2011 Jan;18(1):29-45. doi: 10.1097/PAP.0b013e318202645a. PMID: 21169736

Diagnosis

Thompson LDR, Whaley RD
Surg Pathol Clin 2021 Mar;14(1):75-96. doi: 10.1016/j.path.2020.09.009. PMID: 33526225
Todorovic E, Weinreb I
Surg Pathol Clin 2021 Mar;14(1):1-15. Epub 2021 Jan 6 doi: 10.1016/j.path.2020.09.003. PMID: 33526215
Point du Jour K, Griffith CC
Acta Cytol 2020;64(1-2):92-102. Epub 2019 Mar 25 doi: 10.1159/000497109. PMID: 30909279
Parekh V, Stevens TM
Arch Pathol Lab Med 2016 Sep;140(9):997-1001. doi: 10.5858/arpa.2015-0075-RS. PMID: 27575269
Gupta R, Balasubramanian D, Clark JR
Oral Surg Oral Med Oral Pathol Oral Radiol 2015 Jun;119(6):661-74. Epub 2015 Mar 2 doi: 10.1016/j.oooo.2015.02.481. PMID: 25840511

Therapy

Albert CM, Davis JL, Federman N, Casanova M, Laetsch TW
J Clin Oncol 2019 Feb 20;37(6):513-524. Epub 2018 Dec 28 doi: 10.1200/JCO.18.00573. PMID: 30592640
Locati LD, Perrone F, Cortelazzi B, Lo Vullo S, Bossi P, Dagrada G, Quattrone P, Bergamini C, Potepan P, Civelli E, Fallai C, Pilotti S, Licitra L
Head Neck 2016 May;38(5):724-31. Epub 2015 Jun 25 doi: 10.1002/hed.23940. PMID: 25522335
Kato S, Elkin SK, Schwaederle M, Tomson BN, Helsten T, Carter JL, Kurzrock R
Oncotarget 2015 Sep 22;6(28):25631-45. doi: 10.18632/oncotarget.4554. PMID: 26247885Free PMC Article
Lee JS, Kwon OJ, Park JJ, Seo JH
J Oral Maxillofac Surg 2014 May;72(5):1023-31. Epub 2013 Nov 22 doi: 10.1016/j.joms.2013.11.014. PMID: 24480767
Nabili V, Tan JW, Bhuta S, Sercarz JA, Head CS
Head Neck 2007 Oct;29(10):907-12. doi: 10.1002/hed.20614. PMID: 17563907

Prognosis

Thompson LDR, Whaley RD
Surg Pathol Clin 2021 Mar;14(1):75-96. doi: 10.1016/j.path.2020.09.009. PMID: 33526225
Todorovic E, Weinreb I
Surg Pathol Clin 2021 Mar;14(1):1-15. Epub 2021 Jan 6 doi: 10.1016/j.path.2020.09.003. PMID: 33526215
Luk PP, Selinger CI, Cooper WA, Mahar A, Palme CE, O'Toole SA, Clark JR, Gupta R
Head Neck Pathol 2019 Sep;13(3):397-414. Epub 2018 Nov 22 doi: 10.1007/s12105-018-0988-1. PMID: 30467669Free PMC Article
Parekh V, Stevens TM
Arch Pathol Lab Med 2016 Sep;140(9):997-1001. doi: 10.5858/arpa.2015-0075-RS. PMID: 27575269
Gupta R, Balasubramanian D, Clark JR
Oral Surg Oral Med Oral Pathol Oral Radiol 2015 Jun;119(6):661-74. Epub 2015 Mar 2 doi: 10.1016/j.oooo.2015.02.481. PMID: 25840511

Clinical prediction guides

Bishop JA, Sajed DP
Adv Anat Pathol 2023 Mar 1;30(2):130-135. Epub 2022 Dec 19 doi: 10.1097/PAP.0000000000000385. PMID: 36729381
Locati LD, Collini P, Imbimbo M, Barisella M, Testi A, Licitra LF, Löning T, Tiemann K, Quattrone P, Bimbatti E, Chiaravalli S, Casanova M, Tamborini E, Carta R, Gasparini P, Guzzo M, Massimino M, Ferrari A
Pediatr Blood Cancer 2017 Sep;64(9) Epub 2017 Jan 31 doi: 10.1002/pbc.26468. PMID: 28139061
Wenig BM
Semin Diagn Pathol 2015 Jan;32(1):74-86. Epub 2014 Dec 19 doi: 10.1053/j.semdp.2014.12.004. PMID: 25804344
Michal M, Kacerovska D, Kazakov DV
Head Neck Pathol 2013 Jul;7 Suppl 1(Suppl 1):S3-11. Epub 2013 Jul 3 doi: 10.1007/s12105-013-0457-9. PMID: 23821209Free PMC Article
Seethala RR
Adv Anat Pathol 2011 Jan;18(1):29-45. doi: 10.1097/PAP.0b013e318202645a. PMID: 21169736

Recent systematic reviews

White VA, Hyrcza MD, Lennerz JK, Thierauf J, Lokuhetty D, Cree IA, Indave BI
Mod Pathol 2022 Oct;35(10):1484-1493. Epub 2022 Jul 23 doi: 10.1038/s41379-022-01100-z. PMID: 35871081Free PMC Article
Wang H, Weiss VL, Hoffman RD, Abel T, Ho RH, Borinstein SC, Mannion K, Bridge JA, Black J, Liang J
Head Neck Pathol 2021 Mar;15(1):236-243. Epub 2020 Feb 19 doi: 10.1007/s12105-020-01141-3. PMID: 32077054Free PMC Article
de Almeida-Pinto YD, Costa SFDS, de Andrade BAB, Altemani A, Vargas PA, Abreu LG, Fonseca FP
Oral Dis 2019 Jul;25(5):1277-1282. Epub 2019 Jan 1 doi: 10.1111/odi.12984. PMID: 30269389

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