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Anti-cyclic citrullinated peptide antibody positivity

MedGen UID:
1814258
Concept ID:
C5676688
Finding
Synonym: Anti-CCP antibody positivity
 
HPO: HP:0034092

Definition

The presence of autoantibodies (immunoglobulins) in the blood circulation that react against cyclic citrullinated peptide. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnti-cyclic citrullinated peptide antibody positivity

Professional guidelines

PubMed

Sokoll KB, Helliwell P
Expert Opin Pharmacother 2006 Jan;7(1):35-46. doi: 10.1517/14656566.7.1.35. PMID: 16370920

Recent clinical studies

Etiology

Makino H, Kotani T, Hata K, Nishioka D, Yamamoto W, Yoshikawa A, Wada Y, Hiramatsu Y, Shiba H, Nagai K, Katayama M, Son Y, Amuro H, Onishi A, Akashi K, Hara R, Hirano T, Hashimoto M, Takeuchi T
Mod Rheumatol 2023 Aug 25;33(5):928-935. doi: 10.1093/mr/roac115. PMID: 36112486
Wei T, Yang B, Liu H, Xin F, Fu L
Aging (Albany NY) 2020 Feb 29;12(4):3190-3204. doi: 10.18632/aging.102823. PMID: 32112552Free PMC Article
Mochizuki T, Yano K, Ikari K, Okazaki K
Geriatr Gerontol Int 2019 Sep;19(9):907-912. Epub 2019 Jul 24 doi: 10.1111/ggi.13747. PMID: 31342647
Kobak Ş, Karaarslan AA, Yilmaz H, Sever F
BMJ Case Rep 2015 Jul 6;2015 doi: 10.1136/bcr-2014-208803. PMID: 26150618Free PMC Article
Benucci M, Manfredi M, Puttini PS, Atzeni F
Autoimmun Rev 2010 Oct;9(12):801-3. Epub 2010 Jul 23 doi: 10.1016/j.autrev.2010.07.006. PMID: 20656069

Diagnosis

Wei T, Yang B, Liu H, Xin F, Fu L
Aging (Albany NY) 2020 Feb 29;12(4):3190-3204. doi: 10.18632/aging.102823. PMID: 32112552Free PMC Article
Mochizuki T, Yano K, Ikari K, Okazaki K
Geriatr Gerontol Int 2019 Sep;19(9):907-912. Epub 2019 Jul 24 doi: 10.1111/ggi.13747. PMID: 31342647
Kobak Ş, Karaarslan AA, Yilmaz H, Sever F
BMJ Case Rep 2015 Jul 6;2015 doi: 10.1136/bcr-2014-208803. PMID: 26150618Free PMC Article
Benucci M, Manfredi M, Puttini PS, Atzeni F
Autoimmun Rev 2010 Oct;9(12):801-3. Epub 2010 Jul 23 doi: 10.1016/j.autrev.2010.07.006. PMID: 20656069
Sokoll KB, Helliwell P
Expert Opin Pharmacother 2006 Jan;7(1):35-46. doi: 10.1517/14656566.7.1.35. PMID: 16370920

Therapy

Kawashiri SY, Endo Y, Okamoto M, Tsuji S, Shimizu T, Sumiyoshi R, Koga T, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Kawakami A
Mod Rheumatol 2021 Mar;31(2):343-349. Epub 2020 Jul 31 doi: 10.1080/14397595.2020.1795392. PMID: 32654596
Mochizuki T, Yano K, Ikari K, Okazaki K
Geriatr Gerontol Int 2019 Sep;19(9):907-912. Epub 2019 Jul 24 doi: 10.1111/ggi.13747. PMID: 31342647
Kobak Ş, Karaarslan AA, Yilmaz H, Sever F
BMJ Case Rep 2015 Jul 6;2015 doi: 10.1136/bcr-2014-208803. PMID: 26150618Free PMC Article
Benucci M, Manfredi M, Puttini PS, Atzeni F
Autoimmun Rev 2010 Oct;9(12):801-3. Epub 2010 Jul 23 doi: 10.1016/j.autrev.2010.07.006. PMID: 20656069
Sokoll KB, Helliwell P
Expert Opin Pharmacother 2006 Jan;7(1):35-46. doi: 10.1517/14656566.7.1.35. PMID: 16370920

Prognosis

Makino H, Kotani T, Hata K, Nishioka D, Yamamoto W, Yoshikawa A, Wada Y, Hiramatsu Y, Shiba H, Nagai K, Katayama M, Son Y, Amuro H, Onishi A, Akashi K, Hara R, Hirano T, Hashimoto M, Takeuchi T
Mod Rheumatol 2023 Aug 25;33(5):928-935. doi: 10.1093/mr/roac115. PMID: 36112486
Wei T, Yang B, Liu H, Xin F, Fu L
Aging (Albany NY) 2020 Feb 29;12(4):3190-3204. doi: 10.18632/aging.102823. PMID: 32112552Free PMC Article
Mochizuki T, Yano K, Ikari K, Okazaki K
Geriatr Gerontol Int 2019 Sep;19(9):907-912. Epub 2019 Jul 24 doi: 10.1111/ggi.13747. PMID: 31342647
Kobak Ş, Karaarslan AA, Yilmaz H, Sever F
BMJ Case Rep 2015 Jul 6;2015 doi: 10.1136/bcr-2014-208803. PMID: 26150618Free PMC Article
Benucci M, Manfredi M, Puttini PS, Atzeni F
Autoimmun Rev 2010 Oct;9(12):801-3. Epub 2010 Jul 23 doi: 10.1016/j.autrev.2010.07.006. PMID: 20656069

Clinical prediction guides

Makino H, Kotani T, Hata K, Nishioka D, Yamamoto W, Yoshikawa A, Wada Y, Hiramatsu Y, Shiba H, Nagai K, Katayama M, Son Y, Amuro H, Onishi A, Akashi K, Hara R, Hirano T, Hashimoto M, Takeuchi T
Mod Rheumatol 2023 Aug 25;33(5):928-935. doi: 10.1093/mr/roac115. PMID: 36112486
Wei T, Yang B, Liu H, Xin F, Fu L
Aging (Albany NY) 2020 Feb 29;12(4):3190-3204. doi: 10.18632/aging.102823. PMID: 32112552Free PMC Article
Mochizuki T, Yano K, Ikari K, Okazaki K
Geriatr Gerontol Int 2019 Sep;19(9):907-912. Epub 2019 Jul 24 doi: 10.1111/ggi.13747. PMID: 31342647
Hodkinson B, Meyer PW, Musenge E, Ally M, Anderson R, Tikly M
Cytokine 2012 Nov;60(2):561-4. Epub 2012 Jul 31 doi: 10.1016/j.cyto.2012.06.190. PMID: 22850274
Benucci M, Manfredi M, Puttini PS, Atzeni F
Autoimmun Rev 2010 Oct;9(12):801-3. Epub 2010 Jul 23 doi: 10.1016/j.autrev.2010.07.006. PMID: 20656069

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