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Anti-hexokinase-1 antibody positivity

MedGen UID:
1814279
•Concept ID:
C5676710
•
Finding
Synonym: Anti-HK-1 antibody positivity
 
HPO: HP:0034114

Definition

The presence of autoantibodies (immunoglobulins) in the blood circulation that react against hexokinase-1. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnti-hexokinase-1 antibody positivity

Recent clinical studies

Diagnosis

Detection of anti-kelch-like 12 and anti-hexokinase 1 antibodies in primary biliary cholangitis patients in China.
Liu ZY, Xu L, Liu B
Rev Esp Enferm Dig 2021 Aug;113(8):585-590. doi: 10.17235/reed.2020.7483/2020. PMID: 33307711
Novel Anti-Hexokinase 1 Antibodies Are Associated With Poor Prognosis in Patients With Primary Biliary Cholangitis.
Reig A, Norman GL, Garcia M, Shums Z, Ruiz-Gaspà S, Bentow C, Mahler M, Romera MA, Vinas O, Pares A
Am J Gastroenterol 2020 Oct;115(10):1634-1641. doi: 10.14309/ajg.0000000000000690. PMID: 32467507

Therapy

Novel Anti-Hexokinase 1 Antibodies Are Associated With Poor Prognosis in Patients With Primary Biliary Cholangitis.
Reig A, Norman GL, Garcia M, Shums Z, Ruiz-Gaspà S, Bentow C, Mahler M, Romera MA, Vinas O, Pares A
Am J Gastroenterol 2020 Oct;115(10):1634-1641. doi: 10.14309/ajg.0000000000000690. PMID: 32467507

Prognosis

Novel Anti-Hexokinase 1 Antibodies Are Associated With Poor Prognosis in Patients With Primary Biliary Cholangitis.
Reig A, Norman GL, Garcia M, Shums Z, Ruiz-Gaspà S, Bentow C, Mahler M, Romera MA, Vinas O, Pares A
Am J Gastroenterol 2020 Oct;115(10):1634-1641. doi: 10.14309/ajg.0000000000000690. PMID: 32467507

Clinical prediction guides

Novel Anti-Hexokinase 1 Antibodies Are Associated With Poor Prognosis in Patients With Primary Biliary Cholangitis.
Reig A, Norman GL, Garcia M, Shums Z, Ruiz-Gaspà S, Bentow C, Mahler M, Romera MA, Vinas O, Pares A
Am J Gastroenterol 2020 Oct;115(10):1634-1641. doi: 10.14309/ajg.0000000000000690. PMID: 32467507

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