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Osteochondrosis

MedGen UID:
18216
•Concept ID:
C0029429
•
Disease or Syndrome
Synonym: Osteochondroses
SNOMED CT: Osteochondrosis (19579005)
 
HPO: HP:0040188
Monarch Initiative: MONDO:0018381
Orphanet: ORPHA399319

Definition

Abnormal growth ossification centers in children. Initially a degeneration/ necrosis followed by regeneration or recalcification. [from HPO]

Conditions with this feature

Juvenile osteochondrosis of spine
MedGen UID:
19885
•Concept ID:
C0036310
•
Disease or Syndrome
Scheuermann disease is characterized by lumbar or thoracic kyphosis or both, back pain, and a variety of vertebral changes including wedging, endplate irregularity, narrowing of disc spaces, Schmorl nodes, and detached epiphyseal rings. It is reported to occur more frequently in boys than in girls (summary by McKenzie and Sillence, 1992).
See: Condition Record
Juvenile osteochondrosis of spine

Professional guidelines

PubMed

Treatment of Freiberg Disease.
Seybold JD, Zide JR
Foot Ankle Clin 2018 Mar;23(1):157-169. doi: 10.1016/j.fcl.2017.09.011. PMID: 29362030
Millimeter waves in the treatment of neurological manifestations of vertebral osteochondrosis.
Miryutova NF, Levitskii EF, Kozhemyakin AM, Mavlyautdinova IM
Crit Rev Biomed Eng 2001;29(5-6):613-21. doi: 10.1615/critrevbiomedeng.v29.i56.30. PMID: 12434931
Observations on the differential diagnosis and sequelae of juvenile vertebral osteochondrosis.
WILLIAMS ER
Acta Radiol Suppl 1954;116:293-9. PMID: 13228191

Recent clinical studies

Etiology

Osgood-Schlatter disease: a 2020 update of a common knee condition in children.
Ladenhauf HN, Seitlinger G, Green DW
Curr Opin Pediatr 2020 Feb;32(1):107-112. doi: 10.1097/MOP.0000000000000842. PMID: 31714260
Apophysitis and Osteochondrosis: Common Causes of Pain in Growing Bones.
Achar S, Yamanaka J
Am Fam Physician 2019 May 15;99(10):610-618. PMID: 31083875
Blount disease.
Janoyer M
Orthop Traumatol Surg Res 2019 Feb;105(1S):S111-S121. Epub 2018 Feb 23 doi: 10.1016/j.otsr.2018.01.009. PMID: 29481866
Osteochondroses.
Danger F, Wasyliw C, Varich L
Semin Musculoskelet Radiol 2018 Feb;22(1):118-124. Epub 2018 Feb 6 doi: 10.1055/s-0038-1627094. PMID: 29409078
Treatment of Freiberg Disease.
Seybold JD, Zide JR
Foot Ankle Clin 2018 Mar;23(1):157-169. doi: 10.1016/j.fcl.2017.09.011. PMID: 29362030

Diagnosis

Apophysitis and Osteochondrosis: Common Causes of Pain in Growing Bones.
Achar S, Yamanaka J
Am Fam Physician 2019 May 15;99(10):610-618. PMID: 31083875
Osteochondroses.
Danger F, Wasyliw C, Varich L
Semin Musculoskelet Radiol 2018 Feb;22(1):118-124. Epub 2018 Feb 6 doi: 10.1055/s-0038-1627094. PMID: 29409078
Treatment of Osgood-Schlatter disease: review of the literature.
Circi E, Atalay Y, Beyzadeoglu T
Musculoskelet Surg 2017 Dec;101(3):195-200. Epub 2017 Jun 7 doi: 10.1007/s12306-017-0479-7. PMID: 28593576
Sports-related overuse injuries in children.
Launay F
Orthop Traumatol Surg Res 2015 Feb;101(1 Suppl):S139-47. Epub 2014 Dec 30 doi: 10.1016/j.otsr.2014.06.030. PMID: 25555804
Knee conditions.
Cunill-De Sautu B, Gereige RS
Pediatr Rev 2014 Sep;35(9):359-70. doi: 10.1542/pir.35-9-359. PMID: 25183771

Therapy

A systematic review on conservative treatment options for OSGOOD-Schlatter disease.
Neuhaus C, Appenzeller-Herzog C, Faude O
Phys Ther Sport 2021 May;49:178-187. Epub 2021 Mar 9 doi: 10.1016/j.ptsp.2021.03.002. PMID: 33744766
Treatment of Freiberg Disease.
Seybold JD, Zide JR
Foot Ankle Clin 2018 Mar;23(1):157-169. doi: 10.1016/j.fcl.2017.09.011. PMID: 29362030
van Neck-Odelberg Disease: A 3.5-Year Follow-Up Case Report and Systematic Review.
Mixa PJ, Segreto FA, Luigi-Martinez H, Diebo BG, Naziri Q, Kolla S, Maheshwari AV
Surg Technol Int 2017 Dec 12;31:365-373. PMID: 29316596
Treatment of Infantile Blount Disease: An Update.
Sabharwal S, Sabharwal S
J Pediatr Orthop 2017 Sep;37 Suppl 2:S26-S31. doi: 10.1097/BPO.0000000000001027. PMID: 28799991
Approach to the patient with noninflammatory musculoskeletal pain.
Weiser P
Pediatr Clin North Am 2012 Apr;59(2):471-92. doi: 10.1016/j.pcl.2012.03.012. PMID: 22560580

Prognosis

Blount disease.
Janoyer M
Orthop Traumatol Surg Res 2019 Feb;105(1S):S111-S121. Epub 2018 Feb 23 doi: 10.1016/j.otsr.2018.01.009. PMID: 29481866
Osteochondroses.
Danger F, Wasyliw C, Varich L
Semin Musculoskelet Radiol 2018 Feb;22(1):118-124. Epub 2018 Feb 6 doi: 10.1055/s-0038-1627094. PMID: 29409078
Treatment of Osgood-Schlatter disease: review of the literature.
Circi E, Atalay Y, Beyzadeoglu T
Musculoskelet Surg 2017 Dec;101(3):195-200. Epub 2017 Jun 7 doi: 10.1007/s12306-017-0479-7. PMID: 28593576
Spondylodiscitis.
Márquez Sánchez P
Radiologia 2016 Apr;58 Suppl 1:50-9. Epub 2016 Feb 9 doi: 10.1016/j.rx.2015.12.005. PMID: 26869521
Legg-Calvé-Perthes disease.
Schoenecker PL
Orthop Rev 1986 Sep;15(9):561-74. PMID: 3331009

Clinical prediction guides

Therapeutic interventions in Osgood-Schlatter disease: A case report.
Gaweł E, Zwierzchowska A
Medicine (Baltimore) 2021 Dec 17;100(50):e28257. doi: 10.1097/MD.0000000000028257. PMID: 34918694Free PMC Article
Friedrich Disease: A Case Report.
Maya GF, Nahmad DL, Or O, Safran O, Beyth S
JBJS Case Connect 2020 Jul-Sep;10(3):e20.00027. doi: 10.2106/JBJS.CC.20.00027. PMID: 32865953
Conservative treatment of Osgood-Schlatter disease among young professional soccer players.
Bezuglov EN, Tikhonova АА, Chubarovskiy PV, Repetyuk АD, Khaitin VY, Lazarev AM, Usmanova EM
Int Orthop 2020 Sep;44(9):1737-1743. Epub 2020 Apr 28 doi: 10.1007/s00264-020-04572-3. PMID: 32346752
Blount disease.
Janoyer M
Orthop Traumatol Surg Res 2019 Feb;105(1S):S111-S121. Epub 2018 Feb 23 doi: 10.1016/j.otsr.2018.01.009. PMID: 29481866
Blount disease.
Birch JG
J Am Acad Orthop Surg 2013 Jul;21(7):408-18. doi: 10.5435/JAAOS-21-07-408. PMID: 23818028

Recent systematic reviews

A systematic review on conservative treatment options for OSGOOD-Schlatter disease.
Neuhaus C, Appenzeller-Herzog C, Faude O
Phys Ther Sport 2021 May;49:178-187. Epub 2021 Mar 9 doi: 10.1016/j.ptsp.2021.03.002. PMID: 33744766
Risk factors for failure of temporary hemiepiphysiodesis in Blount disease: a systematic review.
Fan B, Zhao C, Sabharwal S
J Pediatr Orthop B 2020 Jan;29(1):65-72. doi: 10.1097/BPB.0000000000000603. PMID: 30741749
Treatment failures and complications in patients with Blount disease treated with temporary hemiepiphysiodesis: a critical systematic literature review.
Burghardt RD, Herzenberg JE, Andre Strahl, Bernius P, Kazim MA
J Pediatr Orthop B 2018 Nov;27(6):522-529. doi: 10.1097/BPB.0000000000000523. PMID: 29889697
Outcomes and Complications of Tibial Tubercle Fractures in Pediatric Patients: A Systematic Review of the Literature.
Pretell-Mazzini J, Kelly DM, Sawyer JR, Esteban EM, Spence DD, Warner WC Jr, Beaty JH
J Pediatr Orthop 2016 Jul-Aug;36(5):440-6. doi: 10.1097/BPO.0000000000000488. PMID: 25887827
Surgical treatment of osteochondritis dissecans of the talus: a systematic review.
Zwingmann J, Südkamp NP, Schmal H, Niemeyer P
Arch Orthop Trauma Surg 2012 Sep;132(9):1241-50. Epub 2012 May 24 doi: 10.1007/s00402-012-1544-1. PMID: 22622794

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