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Pineocytoma

MedGen UID:
183004
•Concept ID:
C0917890
•
Neoplastic Process
Synonyms: Pinealocytoma; Pineocytoma (disease)
SNOMED CT: Pineocytoma (89096009); Pineocytoma (1156473003)
 
HPO: HP:0030407
Monarch Initiative: MONDO:0016723
Orphanet: ORPHA251912

Definition

A type of pineal parenchymal cell neoplasm that is a mature well-differentiated tumor (WHO grade I). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPineocytoma
Follow this link to review classifications for Pineocytoma in Orphanet.

Professional guidelines

PubMed

Role of radiosurgery in the management of pineal region tumours: indications, method, outcome.
Balossier A, Blond S, Touzet G, Sarrazin T, Lartigau E, Reyns N
Neurochirurgie 2015 Apr-Jun;61(2-3):216-22. Epub 2014 May 27 doi: 10.1016/j.neuchi.2013.11.007. PMID: 24874722
Pineal tumors: analysis of treatment results in 20 patients.
Amendola BE, Wolf A, Coy SR, Amendola MA, Eber D
J Neurosurg 2005 Jan;102 Suppl:175-9. doi: 10.3171/jns.2005.102.s_supplement.0175. PMID: 15662805
The role of radiosurgery for the treatment of pineal parenchymal tumors.
Hasegawa T, Kondziolka D, Hadjipanayis CG, Flickinger JC, Lunsford LD
Neurosurgery 2002 Oct;51(4):880-9. doi: 10.1097/00006123-200210000-00006. PMID: 12234394

Recent clinical studies

Etiology

Third ventricular meningiomas.
Li P, Diao X, Bi Z, Hao S, Ren X, Zhang J, Xing J
J Clin Neurosci 2015 Nov;22(11):1776-84. Epub 2015 Aug 29 doi: 10.1016/j.jocn.2015.05.025. PMID: 26455422
Contemporary management of pineocytoma.
Clark AJ, Sughrue ME, Aranda D, Parsa AT
Neurosurg Clin N Am 2011 Jul;22(3):403-7, ix. Epub 2011 Jun 16 doi: 10.1016/j.nec.2011.05.004. PMID: 21801989
Tumor control after surgery and radiotherapy for pineocytoma.
Clark AJ, Ivan ME, Sughrue ME, Yang I, Aranda D, Han SJ, Kane AJ, Parsa AT
J Neurosurg 2010 Aug;113(2):319-24. doi: 10.3171/2009.12.JNS091683. PMID: 20136388
Pineocytomas.
Disclafani A, Hudgins RJ, Edwards MS, Wara W, Wilson CB, Levin VA
Cancer 1989 Jan 15;63(2):302-4. doi: 10.1002/1097-0142(19890115)63:2<302::aid-cncr2820630216>3.0.co;2-d. PMID: 2910435
The separation of pineocytoma from pineoblastoma.
Borit A, Blackwood W, Mair WG
Cancer 1980 Mar 15;45(6):1408-18. doi: 10.1002/1097-0142(19800315)45:6<1408::aid-cncr2820450619>3.0.co;2-0. PMID: 6986979

Diagnosis

Third ventricular meningiomas.
Li P, Diao X, Bi Z, Hao S, Ren X, Zhang J, Xing J
J Clin Neurosci 2015 Nov;22(11):1776-84. Epub 2015 Aug 29 doi: 10.1016/j.jocn.2015.05.025. PMID: 26455422
Familial pineocytoma.
Gempt J, Ringel F, Oexle K, Delbridge C, Förschler A, Schlegel J, Meyer B, Schmidt-Graf F
Acta Neurochir (Wien) 2012 Aug;154(8):1413-6. Epub 2012 Jun 15 doi: 10.1007/s00701-012-1402-5. PMID: 22699425
Pineocytoma mimicking a pineal cyst on imaging: true diagnostic dilemma or a case of incomplete imaging?
Fakhran S, Escott EJ
AJNR Am J Neuroradiol 2008 Jan;29(1):159-63. Epub 2007 Oct 9 doi: 10.3174/ajnr.A0750. PMID: 17925371Free PMC Article
Pineocytomas.
Disclafani A, Hudgins RJ, Edwards MS, Wara W, Wilson CB, Levin VA
Cancer 1989 Jan 15;63(2):302-4. doi: 10.1002/1097-0142(19890115)63:2<302::aid-cncr2820630216>3.0.co;2-d. PMID: 2910435
The separation of pineocytoma from pineoblastoma.
Borit A, Blackwood W, Mair WG
Cancer 1980 Mar 15;45(6):1408-18. doi: 10.1002/1097-0142(19800315)45:6<1408::aid-cncr2820450619>3.0.co;2-0. PMID: 6986979

Therapy

Usefulness and safety from stereotactic biopsy in posterior fossa lesions in adult patients.
Moreno-Jiménez S, Martínez-Vaca N, Pérez-Aguilar B, Gómez-Calva B, Díaz-Chávez JJ, Mondragón-Soto MG
Cir Cir 2019;87(5):554-558. doi: 10.24875/CIRU.19000717. PMID: 31448801
Radiosurgery for radiosurgery-induced cavernous malformation.
Park YS, Kim SH, Chang JH, Chang JW, Park YG
World Neurosurg 2011 Jan;75(1):94-8. doi: 10.1016/j.wneu.2010.09.017. PMID: 21492671
Pineal parenchymal tumours: I. Pineocytoma: a tumour responsive to platinum-based chemotherapy.
Jackson AS, Plowman PN
Clin Oncol (R Coll Radiol) 2004 Jun;16(4):238-43. doi: 10.1016/j.clon.2003.11.016. PMID: 15214646
The role of radiosurgery for the treatment of pineal parenchymal tumors.
Hasegawa T, Kondziolka D, Hadjipanayis CG, Flickinger JC, Lunsford LD
Neurosurgery 2002 Oct;51(4):880-9. doi: 10.1097/00006123-200210000-00006. PMID: 12234394
Pineocytoma with intratumoral hemorrhage following ventriculoperitoneal shunt--case report.
Harada K, Hayashi T, Anegawa S, Torigoe R, Maeda K, Toda K, Sugita Y, Utsunomiya H
Neurol Med Chir (Tokyo) 1993 Dec;33(12):836-8. doi: 10.2176/nmc.33.836. PMID: 7512231

Prognosis

Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification.
Gagliardi F, De Domenico P, Garbin E, Snider S, Mortini P
J Pineal Res 2023 Dec;75(4):e12910. Epub 2023 Sep 13 doi: 10.1111/jpi.12910. PMID: 37705383
Third ventricular meningiomas.
Li P, Diao X, Bi Z, Hao S, Ren X, Zhang J, Xing J
J Clin Neurosci 2015 Nov;22(11):1776-84. Epub 2015 Aug 29 doi: 10.1016/j.jocn.2015.05.025. PMID: 26455422
Contemporary management of pineocytoma.
Clark AJ, Sughrue ME, Aranda D, Parsa AT
Neurosurg Clin N Am 2011 Jul;22(3):403-7, ix. Epub 2011 Jun 16 doi: 10.1016/j.nec.2011.05.004. PMID: 21801989
Pineocytomas.
Disclafani A, Hudgins RJ, Edwards MS, Wara W, Wilson CB, Levin VA
Cancer 1989 Jan 15;63(2):302-4. doi: 10.1002/1097-0142(19890115)63:2<302::aid-cncr2820630216>3.0.co;2-d. PMID: 2910435
The separation of pineocytoma from pineoblastoma.
Borit A, Blackwood W, Mair WG
Cancer 1980 Mar 15;45(6):1408-18. doi: 10.1002/1097-0142(19800315)45:6<1408::aid-cncr2820450619>3.0.co;2-0. PMID: 6986979

Clinical prediction guides

Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification.
Gagliardi F, De Domenico P, Garbin E, Snider S, Mortini P
J Pineal Res 2023 Dec;75(4):e12910. Epub 2023 Sep 13 doi: 10.1111/jpi.12910. PMID: 37705383
Third ventricular meningiomas.
Li P, Diao X, Bi Z, Hao S, Ren X, Zhang J, Xing J
J Clin Neurosci 2015 Nov;22(11):1776-84. Epub 2015 Aug 29 doi: 10.1016/j.jocn.2015.05.025. PMID: 26455422
Pathology of pineal parenchymal tumors.
Sato K, Kubota T
Prog Neurol Surg 2009;23:12-25. Epub 2009 Mar 23 doi: 10.1159/000210050. PMID: 19329858
Pathology of pineal region tumors.
Hirato J, Nakazato Y
J Neurooncol 2001 Sep;54(3):239-49. doi: 10.1023/a:1012721723387. PMID: 11767290
Computed tomography of pineal, parapineal, and histologically related tumors.
Zimmerman RA, Bilaniuk LT, Wood JH, Bruce DA, Schut L
Radiology 1980 Dec;137(3):669-77. doi: 10.1148/radiology.137.3.6255511. PMID: 6255511

Recent systematic reviews

Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification.
Gagliardi F, De Domenico P, Garbin E, Snider S, Mortini P
J Pineal Res 2023 Dec;75(4):e12910. Epub 2023 Sep 13 doi: 10.1111/jpi.12910. PMID: 37705383
Tumor control after surgery and radiotherapy for pineocytoma.
Clark AJ, Ivan ME, Sughrue ME, Yang I, Aranda D, Han SJ, Kane AJ, Parsa AT
J Neurosurg 2010 Aug;113(2):319-24. doi: 10.3171/2009.12.JNS091683. PMID: 20136388

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