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Decreased urinary metaepinephrine level

MedGen UID:
1841627
Concept ID:
C5826730
Finding
HPO: HP:0034876

Definition

The concentration of metanephrine in the urine, normalized for urine concentration, is below the lower limit of normal. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased urinary metaepinephrine level

Professional guidelines

PubMed

Csikós E, Horváth A, Ács K, Papp N, Balázs VL, Dolenc MS, Kenda M, Kočevar Glavač N, Nagy M, Protti M, Mercolini L, Horváth G, Farkas Á, On Behalf Of The Oemonom
Molecules 2021 Nov 25;26(23) doi: 10.3390/molecules26237141. PMID: 34885733Free PMC Article
McGrath K, Edi R
Am Fam Physician 2019 Jun 15;99(12):751-759. PMID: 31194487
Chu CM, Lowder JL
Am J Obstet Gynecol 2018 Jul;219(1):40-51. Epub 2018 Jan 2 doi: 10.1016/j.ajog.2017.12.231. PMID: 29305250

Recent clinical studies

Etiology

Lentine KL, Smith JM, Lyden GR, Miller JM, Dolan TG, Bradbrook K, Larkin L, Temple K, Handarova DK, Weiss S, Israni AK, Snyder JJ
Am J Transplant 2024 Feb;24(2S1):S19-S118. doi: 10.1016/j.ajt.2024.01.012. PMID: 38431360
Güven O, Sayılan S, Tataroğlu Ö, Hökenek NM, Keleş DV
Rev Assoc Med Bras (1992) 2023;70(1):e20230799. Epub 2023 Dec 22 doi: 10.1590/1806-9282.20230799. PMID: 38126412Free PMC Article
Verissimo T, Faivre A, Rinaldi A, Lindenmeyer M, Delitsikou V, Veyrat-Durebex C, Heckenmeyer C, Fernandez M, Berchtold L, Dalga D, Cohen C, Naesens M, Ricksten SE, Martin PY, Pugin J, Merlier F, Haupt K, Rutkowski JM, Moll S, Cippà PE, Legouis D, de Seigneux S
J Am Soc Nephrol 2022 Apr;33(4):810-827. Epub 2022 Mar 10 doi: 10.1681/ASN.2021050680. PMID: 35273087Free PMC Article
Chu CM, Lowder JL
Am J Obstet Gynecol 2018 Jul;219(1):40-51. Epub 2018 Jan 2 doi: 10.1016/j.ajog.2017.12.231. PMID: 29305250
Hommos MS, Glassock RJ, Rule AD
J Am Soc Nephrol 2017 Oct;28(10):2838-2844. Epub 2017 Aug 8 doi: 10.1681/ASN.2017040421. PMID: 28790143Free PMC Article

Diagnosis

Li C, Ma Y, Yang C, Hua R, Xie W, Zhang L
JAMA Netw Open 2022 Sep 1;5(9):e2234208. doi: 10.1001/jamanetworkopen.2022.34208. PMID: 36178684Free PMC Article
Yang SS, Tsai JD, Kanematsu A, Han CH
J Infect Chemother 2021 Nov;27(11):1543-1554. Epub 2021 Aug 11 doi: 10.1016/j.jiac.2021.07.014. PMID: 34391623
Matuszkiewicz-Rowińska J, Małyszko J
Pol Arch Intern Med 2020 Dec 22;130(12):1074-1080. Epub 2020 May 19 doi: 10.20452/pamw.15373. PMID: 32426960
Chu CM, Lowder JL
Am J Obstet Gynecol 2018 Jul;219(1):40-51. Epub 2018 Jan 2 doi: 10.1016/j.ajog.2017.12.231. PMID: 29305250
Bent S, Nallamothu BK, Simel DL, Fihn SD, Saint S
JAMA 2002 May 22-29;287(20):2701-10. doi: 10.1001/jama.287.20.2701. PMID: 12020306

Therapy

Güven O, Sayılan S, Tataroğlu Ö, Hökenek NM, Keleş DV
Rev Assoc Med Bras (1992) 2023;70(1):e20230799. Epub 2023 Dec 22 doi: 10.1590/1806-9282.20230799. PMID: 38126412Free PMC Article
Schreiber PW, Sax H, Wolfensberger A, Clack L, Kuster SP; Swissnoso
Infect Control Hosp Epidemiol 2018 Nov;39(11):1277-1295. Epub 2018 Sep 20 doi: 10.1017/ice.2018.183. PMID: 30234463
Chu CM, Lowder JL
Am J Obstet Gynecol 2018 Jul;219(1):40-51. Epub 2018 Jan 2 doi: 10.1016/j.ajog.2017.12.231. PMID: 29305250
Moharamzadeh P, Ojaghihaghighi S, Amjadi M, Rahmani F, Farjamnia A
Am J Emerg Med 2017 Dec;35(12):1922-1925. Epub 2017 Sep 9 doi: 10.1016/j.ajem.2017.09.012. PMID: 28916142
Gambrell RD Jr
Invest Radiol 1986 Apr;21(4):369-78. doi: 10.1097/00004424-198604000-00017. PMID: 3516923

Prognosis

Verissimo T, Faivre A, Rinaldi A, Lindenmeyer M, Delitsikou V, Veyrat-Durebex C, Heckenmeyer C, Fernandez M, Berchtold L, Dalga D, Cohen C, Naesens M, Ricksten SE, Martin PY, Pugin J, Merlier F, Haupt K, Rutkowski JM, Moll S, Cippà PE, Legouis D, de Seigneux S
J Am Soc Nephrol 2022 Apr;33(4):810-827. Epub 2022 Mar 10 doi: 10.1681/ASN.2021050680. PMID: 35273087Free PMC Article
Chu CM, Lowder JL
Am J Obstet Gynecol 2018 Jul;219(1):40-51. Epub 2018 Jan 2 doi: 10.1016/j.ajog.2017.12.231. PMID: 29305250
Buyon JP, Kim MY, Guerra MM, Laskin CA, Petri M, Lockshin MD, Sammaritano L, Branch DW, Porter TF, Sawitzke A, Merrill JT, Stephenson MD, Cohn E, Garabet L, Salmon JE
Ann Intern Med 2015 Aug 4;163(3):153-63. doi: 10.7326/M14-2235. PMID: 26098843Free PMC Article
Edefonti A, Tel F, Testa S, De Palma D
Semin Nucl Med 2014 Mar;44(2):123-8. doi: 10.1053/j.semnuclmed.2013.10.004. PMID: 24484749
Winyard P, Chitty LS
Semin Fetal Neonatal Med 2008 Jun;13(3):142-51. Epub 2007 Dec 11 doi: 10.1016/j.siny.2007.10.009. PMID: 18065301

Clinical prediction guides

Verissimo T, Faivre A, Rinaldi A, Lindenmeyer M, Delitsikou V, Veyrat-Durebex C, Heckenmeyer C, Fernandez M, Berchtold L, Dalga D, Cohen C, Naesens M, Ricksten SE, Martin PY, Pugin J, Merlier F, Haupt K, Rutkowski JM, Moll S, Cippà PE, Legouis D, de Seigneux S
J Am Soc Nephrol 2022 Apr;33(4):810-827. Epub 2022 Mar 10 doi: 10.1681/ASN.2021050680. PMID: 35273087Free PMC Article
Kitai Y, Nangaku M, Yanagita M
Contrib Nephrol 2021;199:266-273. Epub 2021 Aug 3 doi: 10.1159/000517708. PMID: 34343996
Kuppermann N, Dayan PS, Levine DA, Vitale M, Tzimenatos L, Tunik MG, Saunders M, Ruddy RM, Roosevelt G, Rogers AJ, Powell EC, Nigrovic LE, Muenzer J, Linakis JG, Grisanti K, Jaffe DM, Hoyle JD Jr, Greenberg R, Gattu R, Cruz AT, Crain EF, Cohen DM, Brayer A, Borgialli D, Bonsu B, Browne L, Blumberg S, Bennett JE, Atabaki SM, Anders J, Alpern ER, Miller B, Casper TC, Dean JM, Ramilo O, Mahajan P; Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (PECARN)
JAMA Pediatr 2019 Apr 1;173(4):342-351. doi: 10.1001/jamapediatrics.2018.5501. PMID: 30776077Free PMC Article
Chu CM, Lowder JL
Am J Obstet Gynecol 2018 Jul;219(1):40-51. Epub 2018 Jan 2 doi: 10.1016/j.ajog.2017.12.231. PMID: 29305250
Winyard P, Chitty LS
Semin Fetal Neonatal Med 2008 Jun;13(3):142-51. Epub 2007 Dec 11 doi: 10.1016/j.siny.2007.10.009. PMID: 18065301

Recent systematic reviews

Veneri F, Vinceti M, Generali L, Giannone ME, Mazzoleni E, Birnbaum LS, Consolo U, Filippini T
Environ Res 2023 Mar 15;221:115239. Epub 2023 Jan 10 doi: 10.1016/j.envres.2023.115239. PMID: 36639015
Nuffield Department of Population Health Renal Studies Group; SGLT2 inhibitor Meta-Analysis Cardio-Renal Trialists' Consortium
Lancet 2022 Nov 19;400(10365):1788-1801. Epub 2022 Nov 6 doi: 10.1016/S0140-6736(22)02074-8. PMID: 36351458Free PMC Article
Recio-Saucedo A, Dall'Ora C, Maruotti A, Ball J, Briggs J, Meredith P, Redfern OC, Kovacs C, Prytherch D, Smith GB, Griffiths P
J Clin Nurs 2018 Jun;27(11-12):2248-2259. Epub 2017 Oct 16 doi: 10.1111/jocn.14058. PMID: 28859254Free PMC Article
Avni T, Lador A, Lev S, Leibovici L, Paul M, Grossman A
PLoS One 2015;10(8):e0129305. Epub 2015 Aug 3 doi: 10.1371/journal.pone.0129305. PMID: 26237037Free PMC Article
Rahn DD, Carberry C, Sanses TV, Mamik MM, Ward RM, Meriwether KV, Olivera CK, Abed H, Balk EM, Murphy M; Society of Gynecologic Surgeons Systematic Review Group
Obstet Gynecol 2014 Dec;124(6):1147-1156. doi: 10.1097/AOG.0000000000000526. PMID: 25415166Free PMC Article

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