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Abnormal pituitary gland morphology

MedGen UID:
1843446
•Concept ID:
C5779790
•
Anatomical Abnormality
Synonym: Abnormality of the pituitary gland
 
HPO: HP:0012503

Definition

An anomaly of the pituitary gland. [from HPO]

Professional guidelines

PubMed

Diagnosis and management of congenital hypopituitarism in children.
Castets S, Thomas-Teinturier C, Villanueva C, Amsellem J, Barat P, Brun G, Quoc EB, Carel JC, De Filippo GP, Kipnis C, Martinerie L, Vergier J, Saveanu A, Teissier N, Coutant R, Léger J, Reynaud R
Arch Pediatr 2024 Apr;31(3):165-171. Epub 2024 Mar 27 doi: 10.1016/j.arcped.2024.01.003. PMID: 38538470
Primary amenorrhea: diagnosis and management.
Marsh CA, Grimstad FW
Obstet Gynecol Surv 2014 Oct;69(10):603-12. doi: 10.1097/OGX.0000000000000111. PMID: 25336070
Hirsutism. Pathophysiology, clinical evaluation, treatment.
Schwartz FL, Flink EB
Postgrad Med 1985 Jun;77(8):81-6, 90-3. doi: 10.1080/00325481.1985.11699027. PMID: 2987894

Recent clinical studies

Etiology

Interconnection between circadian clocks and thyroid function.
Ikegami K, Refetoff S, Van Cauter E, Yoshimura T
Nat Rev Endocrinol 2019 Oct;15(10):590-600. Epub 2019 Aug 12 doi: 10.1038/s41574-019-0237-z. PMID: 31406343Free PMC Article
Surgery for Cushing's disease in pregnancy: our experience and a literature review.
Jolly K, Darr A, Arlt W, Ahmed S, Karavitaki N
Ann R Coll Surg Engl 2019 Jan;101(1):e26-e31. Epub 2018 Oct 5 doi: 10.1308/rcsann.2018.0175. PMID: 30286651Free PMC Article
Complications of acromegaly: thyroid and colon.
Tirosh A, Shimon I
Pituitary 2017 Feb;20(1):70-75. doi: 10.1007/s11102-016-0744-z. PMID: 27631334
Rathke's cleft cyst.
Larkin S, Karavitaki N, Ansorge O
Handb Clin Neurol 2014;124:255-69. doi: 10.1016/B978-0-444-59602-4.00017-4. PMID: 25248592
Testosterone replacement in men.
Beg S, Al-Khoury L, Cunningham GR
Curr Opin Endocrinol Diabetes Obes 2008 Aug;15(4):364-70. doi: 10.1097/MED.0b013e328305081a. PMID: 18594278

Diagnosis

Neuroimaging of the Pituitary Gland: Practical Anatomy and Pathology.
Chapman PR, Singhal A, Gaddamanugu S, Prattipati V
Radiol Clin North Am 2020 Nov;58(6):1115-1133. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.009. PMID: 33040852
Diabetes insipidus.
Christ-Crain M, Bichet DG, Fenske WK, Goldman MB, Rittig S, Verbalis JG, Verkman AS
Nat Rev Dis Primers 2019 Aug 8;5(1):54. doi: 10.1038/s41572-019-0103-2. PMID: 31395885
Septo-optic dysplasia.
Kumar V, Karunakaran A, Valakada J
Int Ophthalmol 2018 Feb;38(1):337-338. Epub 2017 Jan 3 doi: 10.1007/s10792-016-0437-7. PMID: 28050731
Primary amenorrhea: diagnosis and management.
Marsh CA, Grimstad FW
Obstet Gynecol Surv 2014 Oct;69(10):603-12. doi: 10.1097/OGX.0000000000000111. PMID: 25336070
Pituitary incidentalomas.
Molitch ME
Endocrinol Metab Clin North Am 1997 Dec;26(4):725-40. doi: 10.1016/s0889-8529(05)70279-6. PMID: 9429857

Therapy

Testosterone replacement in men.
Beg S, Al-Khoury L, Cunningham GR
Curr Opin Endocrinol Diabetes Obes 2008 Aug;15(4):364-70. doi: 10.1097/MED.0b013e328305081a. PMID: 18594278
Spontaneous intracranial hypotension.
Mokri B
Curr Neurol Neurosci Rep 2001 Mar;1(2):109-17. doi: 10.1007/s11910-001-0005-y. PMID: 11898506
Spontaneous intracranial hypotension.
Mokri B
Curr Pain Headache Rep 2001 Jun;5(3):284-91. doi: 10.1007/s11916-001-0045-7. PMID: 11309218
Endocrine features of Klinefelter's syndrome.
Hsueh WA, Hsu TH, Federman DD
Medicine (Baltimore) 1978 Sep;57(5):447-61. doi: 10.1097/00005792-197809000-00004. PMID: 355776
Partial hypogonadotrophic hypogonadism: studies of pituitary function and of the pituitary-testicular relationship in two patients.
Baker HW, Burger HG, Hudson B, De Kretser DM
Aust J Exp Biol Med Sci 1972 Dec;50(7):861-72. doi: 10.1038/icb.1972.83. PMID: 4144582

Prognosis

Phakomatoses and Endocrine Gland Tumors: Noteworthy and (Not so) Rare Associations.
Chevalier B, Dupuis H, Jannin A, Lemaitre M, Do Cao C, Cardot-Bauters C, Espiard S, Vantyghem MC
Front Endocrinol (Lausanne) 2021;12:678869. Epub 2021 May 6 doi: 10.3389/fendo.2021.678869. PMID: 34025587Free PMC Article
Testosterone replacement in men.
Beg S, Al-Khoury L, Cunningham GR
Curr Opin Endocrinol Diabetes Obes 2008 Aug;15(4):364-70. doi: 10.1097/MED.0b013e328305081a. PMID: 18594278
Rathke's cleft cysts.
Kanter AS, Sansur CA, Jane JAJ Jr, Laws ERJ Jr
Front Horm Res 2006;34:127-157. doi: 10.1159/000091579. PMID: 16474219
The craniopharyngioma.
Oskouian RJ, Samii A, Laws ERJ Jr
Front Horm Res 2006;34:105-126. doi: 10.1159/000091578. PMID: 16474218
Neuro-osteology.
Kjaer I
Crit Rev Oral Biol Med 1998;9(2):224-44. doi: 10.1177/10454411980090020501. PMID: 9603237

Clinical prediction guides

Architects of Pituitary Tumour Growth.
Sabatino ME, Grondona E, De Paul AL
Front Endocrinol (Lausanne) 2022;13:924942. Epub 2022 Jun 28 doi: 10.3389/fendo.2022.924942. PMID: 35837315Free PMC Article
Complications of acromegaly: thyroid and colon.
Tirosh A, Shimon I
Pituitary 2017 Feb;20(1):70-75. doi: 10.1007/s11102-016-0744-z. PMID: 27631334
Testosterone replacement in men.
Beg S, Al-Khoury L, Cunningham GR
Curr Opin Endocrinol Diabetes Obes 2008 Aug;15(4):364-70. doi: 10.1097/MED.0b013e328305081a. PMID: 18594278
PIT1 abnormality.
Tatsumi K, Amino N
Growth Horm IGF Res 1999 Jun;9 Suppl B:18-22; discussion 23. doi: 10.1016/s1096-6374(99)80076-8. PMID: 10549301
Pituitary incidentalomas.
Molitch ME
Endocrinol Metab Clin North Am 1997 Dec;26(4):725-40. doi: 10.1016/s0889-8529(05)70279-6. PMID: 9429857

Recent systematic reviews

Primary Tumors of the Posterior Pituitary Gland: A Systematic Review of the Literature in Light of the New 2017 World Health Organization Classification of Pituitary Tumors.
Whipple SG, Savardekar AR, Rao S, Mahadevan A, Guthikonda B, Kosty JA
World Neurosurg 2021 Jan;145:148-158. Epub 2020 Sep 8 doi: 10.1016/j.wneu.2020.09.023. PMID: 32916355
Pituitary volume in individuals at elevated risk for psychosis: A systematic review and meta-analysis.
Saunders TS, Mondelli V, Cullen AE
Schizophr Res 2019 Nov;213:23-31. Epub 2018 Dec 29 doi: 10.1016/j.schres.2018.12.026. PMID: 30600112
Addressing the post-irradiation hypothalamic-pituitary endocrine abnormalities of brain tumors in pediatric patients.
Velentza L, Tolia M, Christakou C, Nikolaou M, Zerdes I, Tsoukalas N, Hajiioannou J, Tsanadis K, Rigas G, Mitsis M, Theodorou K, Pistevou-Gombaki K, Tsekeris P, Kyrgias G
J BUON 2017 Sep-Oct;22(5):1240-1245. PMID: 29135108
Pituitary dysfunction in granulomatosis with polyangiitis.
Esposito D, Trimpou P, Giugliano D, Dehlin M, Ragnarsson O
Pituitary 2017 Oct;20(5):594-601. doi: 10.1007/s11102-017-0811-0. PMID: 28540625Free PMC Article
A systematic review of the activity of the hypothalamic-pituitary-adrenal axis in first episode psychosis.
Borges S, Gayer-Anderson C, Mondelli V
Psychoneuroendocrinology 2013 May;38(5):603-11. Epub 2013 Jan 28 doi: 10.1016/j.psyneuen.2012.12.025. PMID: 23369532

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