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Glossopharyngeal nerve disorder

MedGen UID:
199771
•Concept ID:
C0751941
•
Disease or Syndrome
Synonym: Glossopharyngeal nerve disease
SNOMED CT: Disorder of ninth nerve (80962007); Glossopharyngeal nerve lesion (80962007); Disorder of IXth cranial nerve (80962007); Disorder of glossopharyngeal nerve (80962007); Disorder of the ninth cranial nerve (80962007); Glossopharyngeal nerve disorder (80962007)
 
Monarch Initiative: MONDO:0002639

Definition

A non-neoplastic or neoplastic disorder affecting the glossopharyngeal nerve (ninth cranial nerve). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGlossopharyngeal nerve disorder

Professional guidelines

PubMed

Medication Management of Neuropathic Pain Disorders.
Fisher R, Clarkson E
Dent Clin North Am 2024 Jan;68(1):121-131. Epub 2023 Aug 30 doi: 10.1016/j.cden.2023.07.010. PMID: 37951629
Nerve block for the treatment of headaches and cranial neuralgias - a practical approach.
Dach F, Éckeli ÁL, Ferreira Kdos S, Speciali JG
Headache 2015 Feb;55 Suppl 1:59-71. Epub 2015 Feb 3 doi: 10.1111/head.12516. PMID: 25644836
Treatment for glossopharyngeal neuralgia with peripheral glycerol injection: our experience in twenty-one older patients.
Yue WL, Zhang Y
Clin Otolaryngol 2013 Dec;38(6):533-5. doi: 10.1111/coa.12181. PMID: 24102955

Recent clinical studies

Etiology

Sex, Gender, and Orofacial Pain.
Shaefer JR, Khawaja SN, Bavia PF
Dent Clin North Am 2018 Oct;62(4):665-682. Epub 2018 Aug 2 doi: 10.1016/j.cden.2018.06.001. PMID: 30189989
Vago-glossopharyngeal neuralgia: a literature review of neurosurgical experience.
Chen J, Sindou M
Acta Neurochir (Wien) 2015 Feb;157(2):311-21; discussion 321. Epub 2014 Dec 21 doi: 10.1007/s00701-014-2302-7. PMID: 25526720
Vernet's syndrome after carotid endarterectomy.
Tamaki T, Node Y, Saitoum N, Saigusa H, Yamazaki M, Morita A
Perspect Vasc Surg Endovasc Ther 2013 Dec;25(3-4):65-8. doi: 10.1177/1531003514525476. PMID: 24625858
Taste disorders after tonsillectomy: case report and literature review.
Collet S, Eloy P, Rombaux P, Bertrand B
Ann Otol Rhinol Laryngol 2005 Mar;114(3):233-6. doi: 10.1177/000348940511400312. PMID: 15825575
The cranial nerve vascular compression syndrome: I. A review of treatment.
Møller AR
Acta Neurochir (Wien) 1991;113(1-2):18-23. doi: 10.1007/BF01402109. PMID: 1799139

Diagnosis

Trigeminal and Glossopharyngeal Neuralgia.
Allam AK, Larkin MB, Sharma H, Viswanathan A
Neurol Clin 2024 May;42(2):585-598. Epub 2024 Jan 12 doi: 10.1016/j.ncl.2023.12.011. PMID: 38575268
Neuropathic Orofacial Pain.
Christoforou J
Dent Clin North Am 2018 Oct;62(4):565-584. Epub 2018 Jul 31 doi: 10.1016/j.cden.2018.05.005. PMID: 30189983
Cranial Neuralgias.
Tepper SJ
Continuum (Minneap Minn) 2018 Aug;24(4, Headache):1157-1178. doi: 10.1212/CON.0000000000000637. PMID: 30074554
Cranial neuralgias.
Hupp WS, Firriolo FJ
Dent Clin North Am 2013 Jul;57(3):481-95. Epub 2013 May 21 doi: 10.1016/j.cden.2013.04.009. PMID: 23809305
Glossopharyngeal neuralgia.
Blumenfeld A, Nikolskaya G
Curr Pain Headache Rep 2013 Jul;17(7):343. doi: 10.1007/s11916-013-0343-x. PMID: 23709235

Therapy

Trigeminal and glossopharyngeal neuralgia.
Reddy GD, Viswanathan A
Neurol Clin 2014 May;32(2):539-52. Epub 2013 Dec 28 doi: 10.1016/j.ncl.2013.11.008. PMID: 24703544
Vernet's syndrome after carotid endarterectomy.
Tamaki T, Node Y, Saitoum N, Saigusa H, Yamazaki M, Morita A
Perspect Vasc Surg Endovasc Ther 2013 Dec;25(3-4):65-8. doi: 10.1177/1531003514525476. PMID: 24625858
Cranial neuralgias.
Hupp WS, Firriolo FJ
Dent Clin North Am 2013 Jul;57(3):481-95. Epub 2013 May 21 doi: 10.1016/j.cden.2013.04.009. PMID: 23809305
The mouth in neurological disorders.
Scully Cbe C, Shotts R
Practitioner 2001 Jun;245(1623):539, 542-6, 548-9. PMID: 11436264
Anticonvulsant drugs and chronic pain.
Swerdlow M
Clin Neuropharmacol 1984;7(1):51-82. doi: 10.1097/00002826-198403000-00003. PMID: 6367974

Prognosis

Lower cranial nerve syndromes: a review.
Gutierrez S, Warner T, McCormack E, Werner C, Mathkour M, Iwanaga J, Uz A, Dumont AS, Tubbs RS
Neurosurg Rev 2021 Jun;44(3):1345-1355. Epub 2020 Jul 8 doi: 10.1007/s10143-020-01344-w. PMID: 32638140
Glossopharyngeal Neuralgia: A Multidimensional Challenge.
Sellers A, Simmons M
S D Med 2019 Sep;72(9):393-395. PMID: 31581374
Vernet's syndrome after carotid endarterectomy.
Tamaki T, Node Y, Saitoum N, Saigusa H, Yamazaki M, Morita A
Perspect Vasc Surg Endovasc Ther 2013 Dec;25(3-4):65-8. doi: 10.1177/1531003514525476. PMID: 24625858
Vagolysis.
Hutchinson CD, Jardine DL, Hurrell M
Age Ageing 2008 Sep;37(5):602-4. Epub 2008 Jun 12 doi: 10.1093/ageing/afn105. PMID: 18556705
The cranial nerve vascular compression syndrome: I. A review of treatment.
Møller AR
Acta Neurochir (Wien) 1991;113(1-2):18-23. doi: 10.1007/BF01402109. PMID: 1799139

Clinical prediction guides

How I do it: endoscopic microvascular decompression for glossopharyngeal neuralgia.
Komatsu F, Kishore K, Sengupta R
Acta Neurochir (Wien) 2020 Nov;162(11):2833-2835. Epub 2020 Jun 18 doi: 10.1007/s00701-020-04456-w. PMID: 32556527
Fleece-Bound Tissue Sealing in Microvascular Decompression.
Tanrikulu L, Buchfelder M, Naraghi R
Turk Neurosurg 2017;27(5):763-767. doi: 10.5137/1019-5149.JTN.17462-16.2. PMID: 27593828
Glossopharyngeal neuralgia and radiosurgery.
Martínez-Álvarez R, Martínez-Moreno N, Kusak ME, Rey-Portolés G
J Neurosurg 2014 Dec;121 Suppl:222-5. doi: 10.3171/2014.8.GKS141273. PMID: 25434956
Motor cortex stimulation for neuropathic facial pain.
Rainov NG, Heidecke V
Neurol Res 2003 Mar;25(2):157-61. doi: 10.1179/016164103101201328. PMID: 12635515
Motor speech deficit following carotid endarterectomy.
Evans WE, Mendelowitz DS, Liapis C, Wolfe V, Florence CL
Ann Surg 1982 Oct;196(4):461-4. doi: 10.1097/00000658-198210000-00009. PMID: 7125731Free PMC Article

Recent systematic reviews

Current advances in the surgical treatment of glossopharyngeal neuralgia.
Berckemeyer MA, Suarez-Meade P, Carcelen MFV, Ricci MD, Cheshire WP, Trifiletti DM, Middlebrooks EH, Quinones-Hinojosa A, Grewal SS
Neurosurg Rev 2023 Feb 2;46(1):47. doi: 10.1007/s10143-023-01948-y. PMID: 36725770
Cranial Nerve Disorders Associated With Immune Checkpoint Inhibitors.
Vogrig A, Muñiz-Castrillo S, Joubert B, Picard G, Rogemond V, Skowron F, Egri M, Desestret V, Tilikete C, Psimaras D, Ducray F, Honnorat J
Neurology 2021 Feb 9;96(6):e866-e875. Epub 2020 Dec 14 doi: 10.1212/WNL.0000000000011340. PMID: 33318162
The emerging role of gamma knife radiosurgery in the management of glossopharyngeal neuralgia.
Spina A, Boari N, Gagliardi F, Bailo M, Morselli C, Iannaccone S, Mortini P
Neurosurg Rev 2019 Mar;42(1):31-38. Epub 2017 Jul 26 doi: 10.1007/s10143-017-0886-0. PMID: 28748271
Glossopharyngeal Neuralgia Treatment Outcomes After Nerve Section, Microvascular Decompression, or Stereotactic Radiosurgery: A Systematic Review and Meta-Analysis.
Lu VM, Goyal A, Graffeo CS, Perry A, Jonker BP, Link MJ
World Neurosurg 2018 Dec;120:572-582.e7. Epub 2018 Sep 18 doi: 10.1016/j.wneu.2018.09.042. PMID: 30240868
Pharyngolaryngeal involvement by varicella-zoster virus.
Nisa L, Landis BN, Giger R, Leuchter I
J Voice 2013 Sep;27(5):636-41. Epub 2013 Jun 12 doi: 10.1016/j.jvoice.2013.02.011. PMID: 23769009

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