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Temporomandibular joint dysfunction syndrome

MedGen UID:
21093
Concept ID:
C0039496
Disease or Syndrome
Synonyms: Costen Syndrome; Costen's Syndrome; Costens Syndrome; Joint Syndrome, Temporomandibular; Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint; Syndrome, Costen's; Syndrome, Temporomandibular Joint; Syndrome, TMJ; Temporomandibular Joint Dysfunction Syndrome; Temporomandibular Joint Syndrome; TMJ Syndrome
SNOMED CT: Temporomandibular joint-pain-dysfunction syndrome (386207004); Costen's syndrome (386207004); Mandibular dysfunction (386207004); Costen's complex (386207004); Temporomandibular joint pain dysfunction syndrome (386207004); Snapping jaw (386207004); TMJPDS - temporomandibular joint pain dysfunction syndrome (386207004); TMJ (temporomandibular joint) syndrome (386207004); Temporomandibular joint syndrome (41888000)
 
Monarch Initiative: MONDO:0021895

Definition

A common disorder noted with jaw movement. It may be caused by malocclusion, repetitive use injury, trauma or arthritis. It is more prevalent among females between their second and fourth decades. Clinical signs include preauricular pain, temporomandibular joint clicking (as the mandibular condyle slips from the articulation made with the capsular disc and temporal bone) and restriction of jaw motion. Clinical course is typically benign but may progress to associated headaches, ear and neck pain, tinnitus and dislocation of temporomandibular joint. Prognosis is favorable as a majority of cases will respond to conservative management. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTemporomandibular joint dysfunction syndrome

Professional guidelines

PubMed

Durham J, Ohrbach R, Baad-Hansen L, Davies S, De Laat A, Goncalves DG, Gordan VV, Goulet JP, Häggman-Henrikson B, Horton M, Koutris M, Law A, List T, Lobbezoo F, Michelotti A, Nixdorf DR, Oyarzo JF, Peck C, Penlington C, Raphael KG, Santiago V, Sharma S, Svensson P, Visscher CM, Yoshiki I, Alstergren P; INfORM
J Oral Rehabil 2024 May;51(5):785-794. Epub 2023 Dec 27 doi: 10.1111/joor.13652. PMID: 38151896
Tran C, Ghahreman K, Huppa C, Gallagher JE
Int J Oral Maxillofac Surg 2022 Sep;51(9):1211-1225. Epub 2022 Mar 23 doi: 10.1016/j.ijom.2021.11.009. PMID: 35339331
Asquini G, Rushton A, Pitance L, Heneghan N, Falla D
Syst Rev 2021 Mar 8;10(1):70. doi: 10.1186/s13643-021-01623-7. PMID: 33685496Free PMC Article

Recent clinical studies

Etiology

Al-Ani MZ, Davies SJ, Gray RJ, Sloan P, Glenny AM
Cochrane Database Syst Rev 2016 Jan 4;2016(1):CD002778. doi: 10.1002/14651858.CD002778.pub3. PMID: 26727210Free PMC Article
Wilkes CH
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Forssell H
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Speculand B, Goss AN
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Nel H
J Prosthet Dent 1978 Oct;40(4):438-41. doi: 10.1016/0022-3913(78)90129-4. PMID: 279694

Diagnosis

Lomas J, Gurgenci T, Jackson C, Campbell D
Aust J Gen Pract 2018 Apr;47(4):212-215. doi: 10.31128/AFP-10-17-4375. PMID: 29621862
Miernik M, Wieckiewicz M, Paradowska A, Wieckiewicz W
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Solberg WK
Semin Neurol 1988 Dec;8(4):291-7. doi: 10.1055/s-2008-1041392. PMID: 3074424
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Greene CS
JAMA 1973 Apr 30;224(5):622. PMID: 4739786

Therapy

Al-Ani MZ, Davies SJ, Gray RJ, Sloan P, Glenny AM
Cochrane Database Syst Rev 2016 Jan 4;2016(1):CD002778. doi: 10.1002/14651858.CD002778.pub3. PMID: 26727210Free PMC Article
Craane B, Dijkstra PU, Stappaerts K, De Laat A
J Dent Res 2012 Apr;91(4):364-9. Epub 2012 Feb 8 doi: 10.1177/0022034512438275. PMID: 22318373
Chan SW, Reade PC
Clin Otolaryngol Allied Sci 1994 Oct;19(5):37o-80. doi: 10.1111/j.1365-2273.1994.tb01251.x. PMID: 7834875
Foreman PA
N Z Dent J 1985 Apr;81(364):52-7. PMID: 3897923
Schärer P
Front Oral Physiol 1974;1(0):293-322. PMID: 4609874

Prognosis

Craane B, Dijkstra PU, Stappaerts K, De Laat A
J Dent Res 2012 Apr;91(4):364-9. Epub 2012 Feb 8 doi: 10.1177/0022034512438275. PMID: 22318373
Okeson JP
Tex Dent J 2000 Jul;117(7):64-74. PMID: 11858065
Okeson JP
Northwest Dent 2000 Sep-Oct;79(5):37-44. PMID: 11413614
Von Korff M, Ormel J, Keefe FJ, Dworkin SF
Pain 1992 Aug;50(2):133-149. doi: 10.1016/0304-3959(92)90154-4. PMID: 1408309
Wilkes CH
Arch Otolaryngol Head Neck Surg 1989 Apr;115(4):469-77. doi: 10.1001/archotol.1989.01860280067019. PMID: 2923691

Clinical prediction guides

Takizawa K, Ozasa K, Yan Z, Hitomi S, Fujita-Yoshigaki J, Okubo M, Yoshikawa K, Shinoda M, Eliav E, Noma N
J Oral Sci 2024;66(3):176-181. doi: 10.2334/josnusd.24-0087. PMID: 39010165
Okeson JP
Tex Dent J 2000 Jul;117(7):64-74. PMID: 11858065
Okeson JP
Northwest Dent 2000 Sep-Oct;79(5):37-44. PMID: 11413614
O'Reilly MT, Rinchuse DJ, Close J
Am J Orthod Dentofacial Orthop 1993 May;103(5):459-63. doi: 10.1016/S0889-5406(05)81797-4. PMID: 8480715
Wilkes CH
Arch Otolaryngol Head Neck Surg 1989 Apr;115(4):469-77. doi: 10.1001/archotol.1989.01860280067019. PMID: 2923691

Recent systematic reviews

Almășan O, Hedeșiu M, Băciuț M, Buduru S, Dinu C
J Oral Rehabil 2023 Mar;50(3):243-255. Epub 2023 Jan 12 doi: 10.1111/joor.13409. PMID: 36582136
Stepan L, Shaw CL, Oue S
J Laryngol Otol 2017 Jan;131(S1):S50-S56. Epub 2016 Oct 27 doi: 10.1017/S0022215116009191. PMID: 27786149
Al-Ani MZ, Davies SJ, Gray RJ, Sloan P, Glenny AM
Cochrane Database Syst Rev 2016 Jan 4;2016(1):CD002778. doi: 10.1002/14651858.CD002778.pub3. PMID: 26727210Free PMC Article
Fernández-de-las-Penas C, Svensson P
Curr Rheumatol Rev 2016;12(1):40-54. doi: 10.2174/1573397112666151231110947. PMID: 26717949
Türp JC, Komine F, Hugger A
Clin Oral Investig 2004 Dec;8(4):179-95. Epub 2004 Jun 4 doi: 10.1007/s00784-004-0265-4. PMID: 15179561

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