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Spondylosis

MedGen UID:
21295
Concept ID:
C0038019
Disease or Syndrome
Synonyms: lumbar spondylosis with myelopathy; lumbosacral spondylosis without myelopathy; spondylogenic compression of lumbar spinal cord; spondylogenic compression of thoracic spinal cord; spondylosis; spondylosis with myelopathy; thoracic or lumbar spondylosis with myelopathy
SNOMED CT: Spondylosis (8847002)
 
Monarch Initiative: MONDO:0002253

Definition

A degenerative spinal disease that can involve any part of the vertebra, the intervertebral disk, and the surrounding soft tissue. [from MONDO]

Professional guidelines

PubMed

Prablek M, Gadot R, Xu DS, Ropper AE
Neurol Clin 2023 Feb;41(1):77-85. Epub 2022 Oct 29 doi: 10.1016/j.ncl.2022.07.003. PMID: 36400560
McCormick JR, Sama AJ, Schiller NC, Butler AJ, Donnally CJ 3rd
J Am Board Fam Med 2020 Mar-Apr;33(2):303-313. doi: 10.3122/jabfm.2020.02.190195. PMID: 32179614
Li Y, Peng B
Pain Physician 2015 Jul-Aug;18(4):E583-95. PMID: 26218949

Recent clinical studies

Etiology

Jiang Q, Gao H, Shi X, Wu Y, Ni W, Shang A
Front Endocrinol (Lausanne) 2023;14:1285137. Epub 2023 Oct 31 doi: 10.3389/fendo.2023.1285137. PMID: 38027141Free PMC Article
Taso M, Sommernes JH, Kolstad F, Sundseth J, Bjorland S, Pripp AH, Zwart JA, Brox JI
BMC Musculoskelet Disord 2020 Mar 16;21(1):171. doi: 10.1186/s12891-020-3188-6. PMID: 32178655Free PMC Article
Zuo G, Gao TC, Xue BH, Gu CC, Yan YT, Zhang YW, Liu RJ, Du SQ
Medicine (Baltimore) 2019 Nov;98(48):e17974. doi: 10.1097/MD.0000000000017974. PMID: 31770206Free PMC Article
Iyer A, Azad TD, Tharin S
Clin Spine Surg 2016 Dec;29(10):408-414. doi: 10.1097/BSD.0000000000000397. PMID: 27352369
Jiang SD, Jiang LS, Dai LY
Eur Spine J 2011 Mar;20(3):351-7. Epub 2010 Aug 8 doi: 10.1007/s00586-010-1544-1. PMID: 20694735Free PMC Article

Diagnosis

Williams J, D'Amore P, Redlich N, Darlow M, Suwak P, Sarkovich S, Bhandutia AK
Orthop Clin North Am 2022 Oct;53(4):509-521. Epub 2022 Sep 14 doi: 10.1016/j.ocl.2022.05.007. PMID: 36208893
Theodore N
N Engl J Med 2020 Jul 9;383(2):159-168. doi: 10.1056/NEJMra2003558. PMID: 32640134
McCormick JR, Sama AJ, Schiller NC, Butler AJ, Donnally CJ 3rd
J Am Board Fam Med 2020 Mar-Apr;33(2):303-313. doi: 10.3122/jabfm.2020.02.190195. PMID: 32179614
Cho TA, Bhattacharyya S
Continuum (Minneap Minn) 2018 Apr;24(2, Spinal Cord Disorders):386-406. doi: 10.1212/CON.0000000000000583. PMID: 29613892
Iyer A, Azad TD, Tharin S
Clin Spine Surg 2016 Dec;29(10):408-414. doi: 10.1097/BSD.0000000000000397. PMID: 27352369

Therapy

Ghogawala Z, Terrin N, Dunbar MR, Breeze JL, Freund KM, Kanter AS, Mummaneni PV, Bisson EF, Barker FG 2nd, Schwartz JS, Harrop JS, Magge SN, Heary RF, Fehlings MG, Albert TJ, Arnold PM, Riew KD, Steinmetz MP, Wang MC, Whitmore RG, Heller JG, Benzel EC
JAMA 2021 Mar 9;325(10):942-951. doi: 10.1001/jama.2021.1233. PMID: 33687463Free PMC Article
Taso M, Sommernes JH, Kolstad F, Sundseth J, Bjorland S, Pripp AH, Zwart JA, Brox JI
BMC Musculoskelet Disord 2020 Mar 16;21(1):171. doi: 10.1186/s12891-020-3188-6. PMID: 32178655Free PMC Article
Wang P, Zuo G, Du SQ, Gao TC, Liu RJ, Hou XZ, Ji X, Yin J, Li KM, Zhang Q
Medicine (Baltimore) 2020 Jan;99(5):e18851. doi: 10.1097/MD.0000000000018851. PMID: 32000386Free PMC Article
Alli S, Anderson I, Khan S
Br J Hosp Med (Lond) 2017 Mar 2;78(3):C34-C37. doi: 10.12968/hmed.2017.78.3.C34. PMID: 28277772
Ellenberg MR, Honet JC, Treanor WJ
Arch Phys Med Rehabil 1994 Mar;75(3):342-52. doi: 10.1016/0003-9993(94)90040-x. PMID: 8129590

Prognosis

Kato S
J Clin Neurosci 2020 Nov;81:12-17. Epub 2020 Sep 25 doi: 10.1016/j.jocn.2020.09.012. PMID: 33222899
Taso M, Sommernes JH, Kolstad F, Sundseth J, Bjorland S, Pripp AH, Zwart JA, Brox JI
BMC Musculoskelet Disord 2020 Mar 16;21(1):171. doi: 10.1186/s12891-020-3188-6. PMID: 32178655Free PMC Article
Roh JS, Teng AL, Yoo JU, Davis J, Furey C, Bohlman HH
Orthop Clin North Am 2005 Jul;36(3):255-62. doi: 10.1016/j.ocl.2005.01.007. PMID: 15950685
McCormack BM, Weinstein PR
West J Med 1996 Jul-Aug;165(1-2):43-51. PMID: 8855684Free PMC Article
Pearce JM
Cephalalgia 1995 Dec;15(6):463-9. doi: 10.1046/j.1468-2982.1995.1506463.x. PMID: 8706108

Clinical prediction guides

Lv J, Mei J, Feng X, Tian X, Sun L
J Orthop Surg Res 2022 Aug 13;17(1):389. doi: 10.1186/s13018-022-03274-3. PMID: 35964065Free PMC Article
Onofrei LV, Henrie AM
Semin Neurol 2021 Jun;41(3):239-246. Epub 2021 May 19 doi: 10.1055/s-0041-1725144. PMID: 34010970
Xydis VG, Zikou AK, Kostadima V, Astrakas LG, Kosta P, Argyropoulou MI
Eur J Radiol 2017 Jun;91:47-51. Epub 2017 Mar 24 doi: 10.1016/j.ejrad.2017.03.017. PMID: 28629570
Cuellar J, Passias P
Bull Hosp Jt Dis (2013) 2017 Jan;75(1):21-29. PMID: 28214458
Ellingson BM, Salamon N, Holly LT
Eur Spine J 2015 Apr;24 Suppl 2(Suppl 2):197-208. Epub 2013 Aug 6 doi: 10.1007/s00586-013-2915-1. PMID: 23917647Free PMC Article

Recent systematic reviews

Zara P, Dinoto A, Carta S, Floris V, Turilli D, Budhram A, Ferrari S, Milia S, Solla P, Mariotto S, Flanagan EP, Lopez Chiriboga AS, Sechi E
Eur J Neurol 2023 Oct;30(10):3367-3376. Epub 2023 Jul 19 doi: 10.1111/ene.15983. PMID: 37433584Free PMC Article
Li S, Wang Z, Liu Y, Cao J, Zheng H, Jing Y, Han L, Ma X, Xia R, Yu L
Ear Nose Throat J 2022 Mar;101(3):NP112-NP134. Epub 2020 Aug 10 doi: 10.1177/0145561320943362. PMID: 32776833
Zuo G, Gao TC, Xue BH, Gu CC, Yan YT, Zhang YW, Liu RJ, Du SQ
Medicine (Baltimore) 2019 Nov;98(48):e17974. doi: 10.1097/MD.0000000000017974. PMID: 31770206Free PMC Article
Youssef JA, Heiner AD, Montgomery JR, Tender GC, Lorio MP, Morreale JM, Phillips FM
Spine J 2019 Oct;19(10):1714-1729. Epub 2019 May 7 doi: 10.1016/j.spinee.2019.04.019. PMID: 31075361
Fouyas IP, Statham PF, Sandercock PA, Lynch C
Cochrane Database Syst Rev 2001;(3):CD001466. doi: 10.1002/14651858.CD001466. PMID: 11686992

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