U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal pupillary function

MedGen UID:
214629
•Concept ID:
C0917967
•
Finding; Finding
Synonym: Abnormal pupillary function (disease)
SNOMED CT: Abnormal pupillary function (72124005); Pupillary function anomaly (72124005); Pupil function abnormality (72124005)
 
HPO: HP:0007686
Monarch Initiative: MONDO:0001303

Definition

A functional abnormality of the pupil. [from HPO]

Conditions with this feature

Ophthalmoplegia, external, and myopia
MedGen UID:
326916
•Concept ID:
C1839577
•
Disease or Syndrome
See: Condition Record
Ophthalmoplegia, external, and myopia

Professional guidelines

PubMed

Eyelid ptosis (Blepharoptosis) for the primary care practitioner.
Avdagic E, Phelps PO
Dis Mon 2020 Oct;66(10):101040. Epub 2020 Jun 27 doi: 10.1016/j.disamonth.2020.101040. PMID: 32605719
Aspects of Datura poisoning and treatment.
Krenzelok EP
Clin Toxicol (Phila) 2010 Feb;48(2):104-10. doi: 10.3109/15563651003630672. PMID: 20229618
Emergency management of the unconscious patient.
Mirza Z
Br J Hosp Med (Lond) 2005 Aug;66(8):Suppl M5-7. doi: 10.12968/hmed.2005.66.Sup1.18524. PMID: 16097523

Recent clinical studies

Etiology

Outcome Prognostication of Acute Brain Injury using the Neurological Pupil Index (ORANGE) study: protocol for a prospective, observational, multicentre, international cohort study.
Oddo M, Taccone F, Galimberti S, Rebora P, Citerio G; Orange Study Group
BMJ Open 2021 May 11;11(5):e046948. doi: 10.1136/bmjopen-2020-046948. PMID: 33980528Free PMC Article
Automated Pupillometry Identifies Absence of Intracranial Pressure Elevation in Intracerebral Hemorrhage Patients.
Giede-Jeppe A, Sprügel MI, Huttner HB, Borutta M, Kuramatsu JB, Hoelter P, Engelhorn T, Schwab S, Koehn J
Neurocrit Care 2021 Aug;35(1):210-220. Epub 2020 Dec 24 doi: 10.1007/s12028-020-01146-4. PMID: 33367973Free PMC Article
Ophthalmologic impairment during adulthood in central congenital hypoventilation syndrome: a longitudinal cohort analysis of nine patients.
Boulanger-Scemama E, Fardeau C, Straus C, Simon C, Touitou V, Touhami S, Amini M, Similowski T, LeHoang P
Ophthalmic Genet 2014 Dec;35(4):229-34. Epub 2014 Aug 12 doi: 10.3109/13816810.2014.946056. PMID: 25113442
Autonomic dysfunction in non-paraneoplastic sensory neuronopathy: beyond sensory abnormalities.
Damasceno A, França MC Jr, Cury H, Nucci A
J Neurol 2011 Feb;258(2):231-7. Epub 2010 Sep 5 doi: 10.1007/s00415-010-5730-1. PMID: 20820798
Cholinergic deficiency in Alzheimer's and Parkinson's disease: evaluation with pupillometry.
Fotiou DF, Stergiou V, Tsiptsios D, Lithari C, Nakou M, Karlovasitou A
Int J Psychophysiol 2009 Aug;73(2):143-9. Epub 2009 May 3 doi: 10.1016/j.ijpsycho.2009.01.011. PMID: 19414041

Diagnosis

Outcome Prognostication of Acute Brain Injury using the Neurological Pupil Index (ORANGE) study: protocol for a prospective, observational, multicentre, international cohort study.
Oddo M, Taccone F, Galimberti S, Rebora P, Citerio G; Orange Study Group
BMJ Open 2021 May 11;11(5):e046948. doi: 10.1136/bmjopen-2020-046948. PMID: 33980528Free PMC Article
Automated Pupillometry Identifies Absence of Intracranial Pressure Elevation in Intracerebral Hemorrhage Patients.
Giede-Jeppe A, Sprügel MI, Huttner HB, Borutta M, Kuramatsu JB, Hoelter P, Engelhorn T, Schwab S, Koehn J
Neurocrit Care 2021 Aug;35(1):210-220. Epub 2020 Dec 24 doi: 10.1007/s12028-020-01146-4. PMID: 33367973Free PMC Article
Ophthalmologic impairment during adulthood in central congenital hypoventilation syndrome: a longitudinal cohort analysis of nine patients.
Boulanger-Scemama E, Fardeau C, Straus C, Simon C, Touitou V, Touhami S, Amini M, Similowski T, LeHoang P
Ophthalmic Genet 2014 Dec;35(4):229-34. Epub 2014 Aug 12 doi: 10.3109/13816810.2014.946056. PMID: 25113442
Cholinergic deficiency in Alzheimer's and Parkinson's disease: evaluation with pupillometry.
Fotiou DF, Stergiou V, Tsiptsios D, Lithari C, Nakou M, Karlovasitou A
Int J Psychophysiol 2009 Aug;73(2):143-9. Epub 2009 May 3 doi: 10.1016/j.ijpsycho.2009.01.011. PMID: 19414041
Pupil reaction to light in Alzheimer's disease: evaluation of pupil size changes and mobility.
Fotiou DF, Brozou CG, Haidich AB, Tsiptsios D, Nakou M, Kabitsi A, Giantselidis C, Fotiou F
Aging Clin Exp Res 2007 Oct;19(5):364-71. doi: 10.1007/BF03324716. PMID: 18007114

Prognosis

Outcome Prognostication of Acute Brain Injury using the Neurological Pupil Index (ORANGE) study: protocol for a prospective, observational, multicentre, international cohort study.
Oddo M, Taccone F, Galimberti S, Rebora P, Citerio G; Orange Study Group
BMJ Open 2021 May 11;11(5):e046948. doi: 10.1136/bmjopen-2020-046948. PMID: 33980528Free PMC Article
Automated Pupillometry Identifies Absence of Intracranial Pressure Elevation in Intracerebral Hemorrhage Patients.
Giede-Jeppe A, Sprügel MI, Huttner HB, Borutta M, Kuramatsu JB, Hoelter P, Engelhorn T, Schwab S, Koehn J
Neurocrit Care 2021 Aug;35(1):210-220. Epub 2020 Dec 24 doi: 10.1007/s12028-020-01146-4. PMID: 33367973Free PMC Article
Ophthalmologic impairment during adulthood in central congenital hypoventilation syndrome: a longitudinal cohort analysis of nine patients.
Boulanger-Scemama E, Fardeau C, Straus C, Simon C, Touitou V, Touhami S, Amini M, Similowski T, LeHoang P
Ophthalmic Genet 2014 Dec;35(4):229-34. Epub 2014 Aug 12 doi: 10.3109/13816810.2014.946056. PMID: 25113442
Cholinergic deficiency in Alzheimer's and Parkinson's disease: evaluation with pupillometry.
Fotiou DF, Stergiou V, Tsiptsios D, Lithari C, Nakou M, Karlovasitou A
Int J Psychophysiol 2009 Aug;73(2):143-9. Epub 2009 May 3 doi: 10.1016/j.ijpsycho.2009.01.011. PMID: 19414041
Pupil reaction to light in Alzheimer's disease: evaluation of pupil size changes and mobility.
Fotiou DF, Brozou CG, Haidich AB, Tsiptsios D, Nakou M, Kabitsi A, Giantselidis C, Fotiou F
Aging Clin Exp Res 2007 Oct;19(5):364-71. doi: 10.1007/BF03324716. PMID: 18007114

Clinical prediction guides

Outcome Prognostication of Acute Brain Injury using the Neurological Pupil Index (ORANGE) study: protocol for a prospective, observational, multicentre, international cohort study.
Oddo M, Taccone F, Galimberti S, Rebora P, Citerio G; Orange Study Group
BMJ Open 2021 May 11;11(5):e046948. doi: 10.1136/bmjopen-2020-046948. PMID: 33980528Free PMC Article
Altered pupillary light responses are associated with the severity of autonomic symptoms in patients with Fabry disease.
Bitirgen G, Turkmen K, Zengin N, Malik RA
Sci Rep 2021 Apr 14;11(1):8146. doi: 10.1038/s41598-021-87589-x. PMID: 33854145Free PMC Article
Automated Pupillometry Identifies Absence of Intracranial Pressure Elevation in Intracerebral Hemorrhage Patients.
Giede-Jeppe A, Sprügel MI, Huttner HB, Borutta M, Kuramatsu JB, Hoelter P, Engelhorn T, Schwab S, Koehn J
Neurocrit Care 2021 Aug;35(1):210-220. Epub 2020 Dec 24 doi: 10.1007/s12028-020-01146-4. PMID: 33367973Free PMC Article
Ophthalmologic impairment during adulthood in central congenital hypoventilation syndrome: a longitudinal cohort analysis of nine patients.
Boulanger-Scemama E, Fardeau C, Straus C, Simon C, Touitou V, Touhami S, Amini M, Similowski T, LeHoang P
Ophthalmic Genet 2014 Dec;35(4):229-34. Epub 2014 Aug 12 doi: 10.3109/13816810.2014.946056. PMID: 25113442
Cholinergic deficiency in Alzheimer's and Parkinson's disease: evaluation with pupillometry.
Fotiou DF, Stergiou V, Tsiptsios D, Lithari C, Nakou M, Karlovasitou A
Int J Psychophysiol 2009 Aug;73(2):143-9. Epub 2009 May 3 doi: 10.1016/j.ijpsycho.2009.01.011. PMID: 19414041

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...