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Colloid carcinoma of the pancreas

MedGen UID:
232082
Concept ID:
C1333081
Neoplastic Process
Synonyms: colloid carcinoma of the pancreas; Mucinous Noncystic Carcinoma; mucinous Noncystic carcinoma; Pancreatic Colloid Carcinoma; Pancreatic Mucinous Noncystic Carcinoma; pancreatic mucinous Noncystic carcinoma
 
Monarch Initiative: MONDO:0004341

Definition

An infiltrating pancreatic ductal adenocarcinoma, characterized by the presence of malignant cells floating in pools of mucin. It has a more favorable prognosis than the conventional infiltrating ductal adenocarcinoma. It often arises in association with intraductal pancreatic mucinous neoplasms and in some cases it may result in the development of pseudomyxoma peritonei. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColloid carcinoma of the pancreas

Professional guidelines

PubMed

Picado O, Dosch AR, Garcia-Buitrago MT, Yakoub D, Dudeja V, Rodgers SE
Pancreas 2021 Mar 1;50(3):306-312. doi: 10.1097/MPA.0000000000001787. PMID: 33835960

Recent clinical studies

Etiology

Dronov AI, Zemskov SV, Kryuchina EA
Klin Khir 2016 Oct;(10):26-30. PMID: 30479109
Allen PJ, Iacobuzio-Donahue CA, Klimstra DS
Clin Cancer Res 2016 Oct 15;22(20):4966-4967. Epub 2016 Aug 29 doi: 10.1158/1078-0432.CCR-16-1462. PMID: 27573170
Sahora K, Fernández-del Castillo C
Curr Opin Gastroenterol 2015 Sep;31(5):424-9. doi: 10.1097/MOG.0000000000000198. PMID: 26125316
Klöppel G, Basturk O, Schlitter AM, Konukiewitz B, Esposito I
Semin Diagn Pathol 2014 Nov;31(6):452-466. Epub 2014 Sep 2 doi: 10.1053/j.semdp.2014.08.005. PMID: 25282472
Käppeli RM, Müller SA, Hummel B, Kruse C, Müller P, Fornaro J, Wilhelm A, Zadnikar M, Schmied BM, Tarantino I
Langenbecks Arch Surg 2013 Dec;398(8):1029-37. Epub 2013 Sep 3 doi: 10.1007/s00423-013-1106-1. PMID: 23999775

Diagnosis

Dhillon J, Betancourt M
Monogr Clin Cytol 2020;26:74-91. Epub 2020 Sep 28 doi: 10.1159/000455736. PMID: 32987385
Tanaka M
Pancreas 2014 Nov;43(8):1136-40. doi: 10.1097/MPA.0000000000000233. PMID: 25333396
Käppeli RM, Müller SA, Hummel B, Kruse C, Müller P, Fornaro J, Wilhelm A, Zadnikar M, Schmied BM, Tarantino I
Langenbecks Arch Surg 2013 Dec;398(8):1029-37. Epub 2013 Sep 3 doi: 10.1007/s00423-013-1106-1. PMID: 23999775
Plerhoples TA, Ahdoot M, DiMaio MA, Pai RK, Park WG, Poultsides GA
Dig Dis Sci 2011 May;56(5):1295-8. Epub 2011 Jan 21 doi: 10.1007/s10620-011-1573-6. PMID: 21253833
Fernández-del Castillo C, Adsay NV
Gastroenterology 2010 Sep;139(3):708-13, 713.e1-2. Epub 2010 Jul 19 doi: 10.1053/j.gastro.2010.07.025. PMID: 20650278

Therapy

McGuigan A, Kelly P, Turkington RC, Jones C, Coleman HG, McCain RS
World J Gastroenterol 2018 Nov 21;24(43):4846-4861. doi: 10.3748/wjg.v24.i43.4846. PMID: 30487695Free PMC Article
Heckler M, Michalski CW, Schaefle S, Kaiser J, Büchler MW, Hackert T
Pancreatology 2017 Mar-Apr;17(2):255-262. Epub 2017 Feb 1 doi: 10.1016/j.pan.2017.01.011. PMID: 28189431
Assifi MM, Nguyen PD, Agrawal N, Dedania N, Kennedy EP, Sauter PK, Prestipino A, Winter JM, Yeo CJ, Lavu H
J Gastrointest Surg 2014 Mar;18(3):523-31. Epub 2014 Jan 22 doi: 10.1007/s11605-014-2459-7. PMID: 24449000
Ueno N, Kobayashi N
J Gastroenterol Hepatol 2005 Sep;20(9):1459. doi: 10.1111/j.1440-1746.2005.04079.x. PMID: 16105139
Baer JW
Am J Dig Dis 1974 Jul;19(7):667-72. doi: 10.1007/BF01073022. PMID: 4365963

Prognosis

Zhao X, Li H, Lyu S, Zhai J, Ji Z, Zhang Z, Zhang X, Liu Z, Wang H, Xu J, Fan H, Kou J, Li L, Lang R, He Q
Int J Biol Sci 2021;17(10):2590-2605. Epub 2021 Jun 22 doi: 10.7150/ijbs.58886. PMID: 34326696Free PMC Article
Jayakrishnan T, Pandya D, Monga D
J Gastrointest Cancer 2020 Jun;51(2):658-662. doi: 10.1007/s12029-019-00322-w. PMID: 31811471
Käppeli RM, Müller SA, Hummel B, Kruse C, Müller P, Fornaro J, Wilhelm A, Zadnikar M, Schmied BM, Tarantino I
Langenbecks Arch Surg 2013 Dec;398(8):1029-37. Epub 2013 Sep 3 doi: 10.1007/s00423-013-1106-1. PMID: 23999775
Fernández-del Castillo C, Adsay NV
Gastroenterology 2010 Sep;139(3):708-13, 713.e1-2. Epub 2010 Jul 19 doi: 10.1053/j.gastro.2010.07.025. PMID: 20650278
Goldsmith JD
Am J Clin Pathol 2003 Jun;119 Suppl:S3-16. doi: 10.1309/1H41-NR88-90CJ-1FT7. PMID: 12951841

Clinical prediction guides

Noda J, Takano Y, Yamawaki M, Azami T, Niiya F, Nishimoto F, Nagahama M
Endoscopy 2024 Dec;56(S 01):E709-E710. Epub 2024 Aug 7 doi: 10.1055/a-2371-1009. PMID: 39111765Free PMC Article
Matsuda Y
Pathol Int 2019 Aug;69(8):450-462. Epub 2019 Jul 24 doi: 10.1111/pin.12837. PMID: 31339204
Grotz TE, Fournier KF, Mansfield PF
Surg Oncol Clin N Am 2018 Jul;27(3):443-462. doi: 10.1016/j.soc.2018.02.012. PMID: 29935682
Sahora K, Fernández-del Castillo C
Curr Opin Gastroenterol 2015 Sep;31(5):424-9. doi: 10.1097/MOG.0000000000000198. PMID: 26125316
Fernández-del Castillo C, Adsay NV
Gastroenterology 2010 Sep;139(3):708-13, 713.e1-2. Epub 2010 Jul 19 doi: 10.1053/j.gastro.2010.07.025. PMID: 20650278

Recent systematic reviews

Paolino G, Basturk O, Esposito I, Hong SM, Brosens LA, Tarcan Z, Wood LD, Gkountakos A, Omori Y, Mattiolo P, Ciulla C, Marchegiani G, Pea A, Bevere M, De Robertis R, D'Onofrio M, Salvia R, Cheng L, Furukawa T, Scarpa A, Adsay V, Luchini C
Mod Pathol 2024 Sep;37(9):100554. Epub 2024 Jun 29 doi: 10.1016/j.modpat.2024.100554. PMID: 38950698
Sugawara T, Franco SR, Ishida J, Kalra A, Saben JL, Gálvez KN, Kirsch MJ, Al-Musawi MH, Kaplan B, Pomfret EA, Schulick RD, Del Chiaro M
Am J Transplant 2023 Mar;23(3):429-436. Epub 2023 Jan 12 doi: 10.1016/j.ajt.2022.11.024. PMID: 36695699
Paolino G, Esposito I, Hong SM, Basturk O, Mattiolo P, Kaneko T, Veronese N, Scarpa A, Adsay V, Luchini C
Histopathology 2022 Sep;81(3):297-309. Epub 2022 May 27 doi: 10.1111/his.14698. PMID: 35583805Free PMC Article
Bararia A, Dey S, Gulati S, Ghatak S, Ghosh S, Banerjee S, Sikdar N
Hepatobiliary Pancreat Dis Int 2020 Jun;19(3):205-217. Epub 2020 Apr 8 doi: 10.1016/j.hbpd.2020.03.010. PMID: 32312637
Manuel-Vazquez A, Ramia JM, Latorre-Fragua R, Valle-Rubio A, Arteaga-Peralta V, Ramiro-Pérez C, de la Plaza-Llamas R
Pancreas 2018 May/Jun;47(5):551-555. doi: 10.1097/MPA.0000000000001048. PMID: 29683974

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