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Adenosquamous colon carcinoma

MedGen UID:: 232083
•Concept ID:: C1333082
•: Neoplastic Process

Synonyms:	Adenosquamous Carcinoma of Colon; adenosquamous carcinoma of colon; Adenosquamous Carcinoma of the Colon; adenosquamous carcinoma of the colon; Adenosquamous Colon Carcinoma; adenosquamous colon carcinoma; colon adenosquamous cancer; Colon Adenosquamous Carcinoma; colon adenosquamous carcinoma; Colonic Adenosquamous Carcinoma; colonic adenosquamous carcinoma

Monarch Initiative:	MONDO:0003554

Definition

An unusual colon carcinoma characterized by the presence of glandular and squamous carcinomatous components. The two carcinomatous components may be admixed within the tumor, or the two may appear separately in different areas. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAdenosquamous colon carcinoma

Intestinal disorder
- Colonic disorder
  - Neoplasm of the large intestine
    - Colonic neoplasm
      - Colon cancer
        Carcinoma of colon
        Adenosquamous colon carcinoma

Professional guidelines

PubMed

Presentation, treatment, and prognosis of colorectal adenosquamous carcinoma: A contemporary analysis of the surveillance, epidemiology, and end results database.

Khan AH, Gao X, Goffredo P, Kahl AR, Utria AF, Charlton ME, Ahad S, Hassan I
Am J Surg 2022 May;223(5):957-962. Epub 2021 Sep 11 doi: 10.1016/j.amjsurg.2021.09.004. PMID: 34530984

See all (1)

Recent clinical studies

Etiology

Characteristics of anal canal squamous cell carcinoma as an HPV-associated cancer in Japan.

Yamada K, Shiraishi K, Takashima A, Takayanagi D, Saiki Y, Takano S, Tanaka M, Fukunaga M, Sugimoto K, Iwasaki Y, Nakamura Y, Kuwahara D, Tsuji Y, Takano M, Sugihara K, Ajioka Y
Int J Clin Oncol 2023 Aug;28(8):990-998. Epub 2023 Apr 28 doi: 10.1007/s10147-023-02339-5. PMID: 37115427

Adenosquamous carcinoma: An aggressive histologic sub-type of colon cancer with poor prognosis.

Nasseri Y, Cox B, Shen W, Zhu R, Stettler I, Cohen J, Artinyan A, Gangi A
Am J Surg 2021 Mar;221(3):649-653. Epub 2020 Aug 22 doi: 10.1016/j.amjsurg.2020.07.038. PMID: 32862977

Population-based evaluation of adenosquamous carcinoma of the colon and rectum.

Masoomi H, Ziogas A, Lin BS, Barleben A, Mills S, Stamos MJ, Zell JA
Dis Colon Rectum 2012 May;55(5):509-14. doi: 10.1097/DCR.0b013e3182420953. PMID: 22513428 Free PMC Article

Adenosquamous carcinoma of the colon and rectum.

Petrelli NJ, Valle AA, Weber TK, Rodriguez-Bigas M
Dis Colon Rectum 1996 Nov;39(11):1265-8. doi: 10.1007/BF02055120. PMID: 8918436

Carcinoma of the endometrium.

Cavanagh D, Marsden DE, Ruffolo EH
Obstet Gynecol Annu 1984;13:211-60. PMID: 6371616

See all (27)

Diagnosis

Characteristics of anal canal squamous cell carcinoma as an HPV-associated cancer in Japan.

A Case Report of Metachronous Multiple Adenosquamous Carcinoma of the Colon Over-expressing PD-L1 and a Literature Review.

Akahoshi S, Yamamura K, Komohara Y, Yoshii D, Oda E, Sato N, Yuki H, Yukimura K, Beppu T
Anticancer Res 2021 Nov;41(11):5847-5854. doi: 10.21873/anticanres.15404. PMID: 34732461

Adenosquamous carcinoma of the right colon with diffuse signet-ring mucinous component.

Di Prete M, Baciorri F, Franceschilli M, Bagaglini G, Sica G, Doldo E, Palmieri G, Orlandi A
Clin J Gastroenterol 2020 Aug;13(4):555-559. Epub 2020 Feb 5 doi: 10.1007/s12328-020-01101-y. PMID: 32026256

Population-based evaluation of adenosquamous carcinoma of the colon and rectum.

Masoomi H, Ziogas A, Lin BS, Barleben A, Mills S, Stamos MJ, Zell JA
Dis Colon Rectum 2012 May;55(5):509-14. doi: 10.1097/DCR.0b013e3182420953. PMID: 22513428 Free PMC Article

Carcinoma of the endometrium.

Cavanagh D, Marsden DE, Ruffolo EH
Obstet Gynecol Annu 1984;13:211-60. PMID: 6371616

See all (52)

Therapy

Application of colon interposition among the esophageal cancer patients with partial gastrectomy.

Chen Q, Mao W, Yu H, Liang Y, Wang J, Chen G
J Cancer Res Ther 2016 Dec;12(Supplement):C212-C216. doi: 10.4103/0973-1482.200602. PMID: 28230019

The prognostic significance of pretreatment leukocytosis in patients with anal cancer treated with radical chemoradiotherapy or radiotherapy.

Banerjee R, Roxin G, Eliasziw M, Joseph K, Maclean A, Buie WD, Doll C
Dis Colon Rectum 2013 Sep;56(9):1036-42. doi: 10.1097/DCR.0b013e31829ab0d4. PMID: 23929012

Adenosquamous carcinoma of the rectum showing endocrine-cell differentiation: report of a case.

Kono T, Yamamoto Y, Kakisaka A, Tokusasi Y, Miyokawa N, Kasai S
Dis Colon Rectum 1999 Aug;42(8):1089-92. doi: 10.1007/BF02236710. PMID: 10458137

Squamous-cell carcinoma of the colon responsive to combination chemotherapy: report of two cases and review of the literature.

Juturi JV, Francis B, Koontz PW, Wilkes JD
Dis Colon Rectum 1999 Jan;42(1):102-9. doi: 10.1007/BF02235191. PMID: 10211528

Carcinoma of the endometrium.

Cavanagh D, Marsden DE, Ruffolo EH
Obstet Gynecol Annu 1984;13:211-60. PMID: 6371616

See all (8)

Prognosis

Epidemiology and survival outcomes in adenosquamous carcinoma: a population-based study.

Cheng C, Luo Z, Xiong W, Shi Z, Tan H
Int J Colorectal Dis 2022 Jul;37(7):1581-1592. Epub 2022 Jun 9 doi: 10.1007/s00384-022-04198-4. PMID: 35678851

Presentation, treatment, and prognosis of colorectal adenosquamous carcinoma: A contemporary analysis of the surveillance, epidemiology, and end results database.

Khan AH, Gao X, Goffredo P, Kahl AR, Utria AF, Charlton ME, Ahad S, Hassan I
Am J Surg 2022 May;223(5):957-962. Epub 2021 Sep 11 doi: 10.1016/j.amjsurg.2021.09.004. PMID: 34530984

Adenosquamous carcinoma: An aggressive histologic sub-type of colon cancer with poor prognosis.

Nasseri Y, Cox B, Shen W, Zhu R, Stettler I, Cohen J, Artinyan A, Gangi A
Am J Surg 2021 Mar;221(3):649-653. Epub 2020 Aug 22 doi: 10.1016/j.amjsurg.2020.07.038. PMID: 32862977

Adenosquamous carcinoma of the right colon with diffuse signet-ring mucinous component.

Population-based evaluation of adenosquamous carcinoma of the colon and rectum.

Masoomi H, Ziogas A, Lin BS, Barleben A, Mills S, Stamos MJ, Zell JA
Dis Colon Rectum 2012 May;55(5):509-14. doi: 10.1097/DCR.0b013e3182420953. PMID: 22513428 Free PMC Article

See all (49)

Clinical prediction guides

Epidemiology and survival outcomes in adenosquamous carcinoma: a population-based study.

Cheng C, Luo Z, Xiong W, Shi Z, Tan H
Int J Colorectal Dis 2022 Jul;37(7):1581-1592. Epub 2022 Jun 9 doi: 10.1007/s00384-022-04198-4. PMID: 35678851

Adenosquamous carcinoma of the right colon with diffuse signet-ring mucinous component.

Intestinal adenosquamous carcinoma with a synchronous skin metastasis: a immunohistochemical and molecular analysis.

Parente P, Covelli C, Parrella P, Latiano TP, Fiordelisi F, Pellico MT, Maiello E, Graziano P
Int J Colorectal Dis 2020 Feb;35(2):337-341. Epub 2019 Dec 10 doi: 10.1007/s00384-019-03464-2. PMID: 31823050

Colonic adenosquamous carcinoma and mucinous adenocarcinoma with microsatellite instability.

Parra-Medina R, Lopez-Correa P, Gutierrez V, Polo F
Malays J Pathol 2018 Aug;40(2):199-202. PMID: 30173239

Colorectal cancer: prognostic values.

Manxhuka-Kerliu S, Telaku S, Ahmetaj H, Baruti A, Loxha S, Kerliu A
Bosn J Basic Med Sci 2009 Feb;9(1):19-24. doi: 10.17305/bjbms.2009.2851. PMID: 19284390 Free PMC Article

See all (23)

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Adenosquamous colon carcinoma

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

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