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Grade 3a Lesion

MedGen UID:
232562
•Concept ID:
C1333847
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 3a Lesion

Professional guidelines

PubMed

Evidence-based Practice of Preparing the Best Evidence for Intestinal Tract in Elderly Patients Before Colonoscopy.
Rong L, Liu M, Liu L
Altern Ther Health Med 2023 May;29(4):224-233. PMID: 36947658
Electrochemotherapy as palliative treatment in patients with recurrent and/or metastatic head and neck tumours: features analysis for an early determination of the partial responsive patients.
Maglitto F, Salzano G, Longo F, Di Bernardo E, D'Alessio V, Fusco R, Aversa C, Pavone E, Pontone M, Marciano ML, Togo G, De Fazio GR, Ordano D, Maglione MG, Vaira LA, Bergonzani M, Salzano FA, Maiolino P, Califano L, Ionna F, Perri F
Eur Rev Med Pharmacol Sci 2022 Feb;26(4):1350-1363. doi: 10.26355/eurrev_202202_28128. PMID: 35253191
A comprehensive review of paediatric low-grade diffuse glioma: pathology, molecular genetics and treatment.
Ryall S, Tabori U, Hawkins C
Brain Tumor Pathol 2017 Apr;34(2):51-61. Epub 2017 Mar 25 doi: 10.1007/s10014-017-0282-z. PMID: 28342104

Recent clinical studies

Etiology

High prevalence of human papillomavirus type 66 in low-grade cervical lesions of Mexican women.
Juárez-González K, Paredes-Cervantes V, Gordillo-Rodríguez S, González-Guzmán S, Moncayo-Valencia X, Méndez-Martínez R, García-Carrancá A, Martínez-Ezquerro JD, Rivas-Ruiz R, Sánchez-Suárez P, Álvarez-Sandoval P, Padilla-Arrieta P, Martínez-Salazar M, Vázquez-Vega S
Arch Virol 2020 Nov;165(11):2633-2640. Epub 2020 Aug 18 doi: 10.1007/s00705-020-04771-8. PMID: 32812092
Nivolumab versus chemotherapy in patients with advanced oesophageal squamous cell carcinoma refractory or intolerant to previous chemotherapy (ATTRACTION-3): a multicentre, randomised, open-label, phase 3 trial.
Kato K, Cho BC, Takahashi M, Okada M, Lin CY, Chin K, Kadowaki S, Ahn MJ, Hamamoto Y, Doki Y, Yen CC, Kubota Y, Kim SB, Hsu CH, Holtved E, Xynos I, Kodani M, Kitagawa Y
Lancet Oncol 2019 Nov;20(11):1506-1517. Epub 2019 Sep 30 doi: 10.1016/S1470-2045(19)30626-6. PMID: 31582355
Overview of DNA methylation in adult diffuse gliomas.
Aoki K, Natsume A
Brain Tumor Pathol 2019 Apr;36(2):84-91. Epub 2019 Apr 1 doi: 10.1007/s10014-019-00339-w. PMID: 30937703
Lorlatinib in patients with ALK-positive non-small-cell lung cancer: results from a global phase 2 study.
Solomon BJ, Besse B, Bauer TM, Felip E, Soo RA, Camidge DR, Chiari R, Bearz A, Lin CC, Gadgeel SM, Riely GJ, Tan EH, Seto T, James LP, Clancy JS, Abbattista A, Martini JF, Chen J, Peltz G, Thurm H, Ou SI, Shaw AT
Lancet Oncol 2018 Dec;19(12):1654-1667. Epub 2018 Nov 6 doi: 10.1016/S1470-2045(18)30649-1. PMID: 30413378
High-grade pancreatic intraepithelial lesions: prevalence and implications in pancreatic neoplasia.
Park JR, Li F, Oza VM, Sklaw BC, Cronley KM, Wellner M, Swanson B, Krishna SG
Hepatobiliary Pancreat Dis Int 2017 Apr;16(2):202-208. doi: 10.1016/s1499-3872(16)60186-8. PMID: 28381386

Diagnosis

WHO Classification of Tumours fifth edition: evolving issues in the classification, diagnosis, and prognostication of prostate cancer.
Kench JG, Amin MB, Berney DM, Compérat EM, Cree IA, Gill AJ, Hartmann A, Menon S, Moch H, Netto GJ, Raspollini MR, Rubin MA, Tan PH, Tsuzuki T, Turjalic S, van der Kwast TH, Zhou M, Srigley JR
Histopathology 2022 Oct;81(4):447-458. Epub 2022 Aug 2 doi: 10.1111/his.14711. PMID: 35758185Free PMC Article
High prevalence of human papillomavirus type 66 in low-grade cervical lesions of Mexican women.
Juárez-González K, Paredes-Cervantes V, Gordillo-Rodríguez S, González-Guzmán S, Moncayo-Valencia X, Méndez-Martínez R, García-Carrancá A, Martínez-Ezquerro JD, Rivas-Ruiz R, Sánchez-Suárez P, Álvarez-Sandoval P, Padilla-Arrieta P, Martínez-Salazar M, Vázquez-Vega S
Arch Virol 2020 Nov;165(11):2633-2640. Epub 2020 Aug 18 doi: 10.1007/s00705-020-04771-8. PMID: 32812092
(13)N-NH(3) PET/CT in oncological disease.
Albano D, Giubbini R, Bertagna F
Jpn J Radiol 2019 Dec;37(12):799-807. Epub 2019 Oct 10 doi: 10.1007/s11604-019-00883-7. PMID: 31599383
Overview of DNA methylation in adult diffuse gliomas.
Aoki K, Natsume A
Brain Tumor Pathol 2019 Apr;36(2):84-91. Epub 2019 Apr 1 doi: 10.1007/s10014-019-00339-w. PMID: 30937703
Histone H3 K27M mutations in adult cerebellar high-grade gliomas.
Nakata S, Nobusawa S, Yamazaki T, Osawa T, Horiguchi K, Hashiba Y, Yaoita H, Matsumura N, Ikota H, Hirato J, Yoshimoto Y, Yokoo H
Brain Tumor Pathol 2017 Jul;34(3):113-119. Epub 2017 May 25 doi: 10.1007/s10014-017-0288-6. PMID: 28547652

Therapy

Adaptive radiotherapy (up to 74 Gy) or standard radiotherapy (66 Gy) for patients with stage III non-small-cell lung cancer, according to [(18)F]FDG-PET tumour residual uptake at 42 Gy (RTEP7-IFCT-1402): a multicentre, randomised, controlled phase 2 trial.
Vera P, Thureau S, Le Tinier F, Chaumet-Riffaud P, Hapdey S, Kolesnikov-Gauthier H, Martin E, Berriolo-Riedinger A, Pourel N, Broglia JM, Boissellier P, Guillemard S, Salem N, Brenot-Rossi I, Le Péchoux C, Berthold C, Giroux-Leprieur E, Moreau D, Guillerm S, Benali K, Tessonnier L, Audigier-Valette C, Lerouge D, Quak E, Massabeau C, Courbon F, Moisson P, Larrouy A, Modzelewski R, Gouel P, Ghazzar N, Langlais A, Amour E, Zalcman G, Giraud P
Lancet Oncol 2024 Sep;25(9):1176-1187. Epub 2024 Aug 9 doi: 10.1016/S1470-2045(24)00320-6. PMID: 39134086
Odronextamab, a human CD20×CD3 bispecific antibody in patients with CD20-positive B-cell malignancies (ELM-1): results from the relapsed or refractory non-Hodgkin lymphoma cohort in a single-arm, multicentre, phase 1 trial.
Bannerji R, Arnason JE, Advani RH, Brown JR, Allan JN, Ansell SM, Barnes JA, O'Brien SM, Chávez JC, Duell J, Rosenwald A, Crombie JL, Ufkin M, Li J, Zhu M, Ambati SR, Chaudhry A, Lowy I, Topp MS
Lancet Haematol 2022 May;9(5):e327-e339. Epub 2022 Apr 1 doi: 10.1016/S2352-3026(22)00072-2. PMID: 35366963Free PMC Article
Nivolumab versus chemotherapy in patients with advanced oesophageal squamous cell carcinoma refractory or intolerant to previous chemotherapy (ATTRACTION-3): a multicentre, randomised, open-label, phase 3 trial.
Kato K, Cho BC, Takahashi M, Okada M, Lin CY, Chin K, Kadowaki S, Ahn MJ, Hamamoto Y, Doki Y, Yen CC, Kubota Y, Kim SB, Hsu CH, Holtved E, Xynos I, Kodani M, Kitagawa Y
Lancet Oncol 2019 Nov;20(11):1506-1517. Epub 2019 Sep 30 doi: 10.1016/S1470-2045(19)30626-6. PMID: 31582355
Lorlatinib in patients with ALK-positive non-small-cell lung cancer: results from a global phase 2 study.
Solomon BJ, Besse B, Bauer TM, Felip E, Soo RA, Camidge DR, Chiari R, Bearz A, Lin CC, Gadgeel SM, Riely GJ, Tan EH, Seto T, James LP, Clancy JS, Abbattista A, Martini JF, Chen J, Peltz G, Thurm H, Ou SI, Shaw AT
Lancet Oncol 2018 Dec;19(12):1654-1667. Epub 2018 Nov 6 doi: 10.1016/S1470-2045(18)30649-1. PMID: 30413378
Outbreak of varicella among vaccinated children--Michigan, 2003.
Centers for Disease Control and Prevention (CDC)
MMWR Morb Mortal Wkly Rep 2004 May 14;53(18):389-92. PMID: 15138400

Prognosis

Non-invasive early detection on esophageal squamous cell carcinoma and precancerous lesions by microbial biomarkers combining epidemiological factors in China.
Li M, Shao D, Fan Z, Qin J, Xu J, Huang Q, Li X, Hua Z, Li J, Hao C, Wei W, Abnet CC
J Gastroenterol 2024 Jul;59(7):531-542. Epub 2024 May 31 doi: 10.1007/s00535-024-02117-8. PMID: 38819499
WHO Classification of Tumours fifth edition: evolving issues in the classification, diagnosis, and prognostication of prostate cancer.
Kench JG, Amin MB, Berney DM, Compérat EM, Cree IA, Gill AJ, Hartmann A, Menon S, Moch H, Netto GJ, Raspollini MR, Rubin MA, Tan PH, Tsuzuki T, Turjalic S, van der Kwast TH, Zhou M, Srigley JR
Histopathology 2022 Oct;81(4):447-458. Epub 2022 Aug 2 doi: 10.1111/his.14711. PMID: 35758185Free PMC Article
Overview of DNA methylation in adult diffuse gliomas.
Aoki K, Natsume A
Brain Tumor Pathol 2019 Apr;36(2):84-91. Epub 2019 Apr 1 doi: 10.1007/s10014-019-00339-w. PMID: 30937703
Histone H3 K27M mutations in adult cerebellar high-grade gliomas.
Nakata S, Nobusawa S, Yamazaki T, Osawa T, Horiguchi K, Hashiba Y, Yaoita H, Matsumura N, Ikota H, Hirato J, Yoshimoto Y, Yokoo H
Brain Tumor Pathol 2017 Jul;34(3):113-119. Epub 2017 May 25 doi: 10.1007/s10014-017-0288-6. PMID: 28547652
Clinical significance of serum-soluble interleukin-2 receptor in patients with follicular lymphoma.
Yoshizato T, Nannya Y, Imai Y, Ichikawa M, Kurokawa M
Clin Lymphoma Myeloma Leuk 2013 Aug;13(4):410-6. Epub 2013 Jun 5 doi: 10.1016/j.clml.2013.03.014. PMID: 23747081

Clinical prediction guides

Adaptive radiotherapy (up to 74 Gy) or standard radiotherapy (66 Gy) for patients with stage III non-small-cell lung cancer, according to [(18)F]FDG-PET tumour residual uptake at 42 Gy (RTEP7-IFCT-1402): a multicentre, randomised, controlled phase 2 trial.
Vera P, Thureau S, Le Tinier F, Chaumet-Riffaud P, Hapdey S, Kolesnikov-Gauthier H, Martin E, Berriolo-Riedinger A, Pourel N, Broglia JM, Boissellier P, Guillemard S, Salem N, Brenot-Rossi I, Le Péchoux C, Berthold C, Giroux-Leprieur E, Moreau D, Guillerm S, Benali K, Tessonnier L, Audigier-Valette C, Lerouge D, Quak E, Massabeau C, Courbon F, Moisson P, Larrouy A, Modzelewski R, Gouel P, Ghazzar N, Langlais A, Amour E, Zalcman G, Giraud P
Lancet Oncol 2024 Sep;25(9):1176-1187. Epub 2024 Aug 9 doi: 10.1016/S1470-2045(24)00320-6. PMID: 39134086
Odronextamab, a human CD20×CD3 bispecific antibody in patients with CD20-positive B-cell malignancies (ELM-1): results from the relapsed or refractory non-Hodgkin lymphoma cohort in a single-arm, multicentre, phase 1 trial.
Bannerji R, Arnason JE, Advani RH, Brown JR, Allan JN, Ansell SM, Barnes JA, O'Brien SM, Chávez JC, Duell J, Rosenwald A, Crombie JL, Ufkin M, Li J, Zhu M, Ambati SR, Chaudhry A, Lowy I, Topp MS
Lancet Haematol 2022 May;9(5):e327-e339. Epub 2022 Apr 1 doi: 10.1016/S2352-3026(22)00072-2. PMID: 35366963Free PMC Article
High prevalence of human papillomavirus type 66 in low-grade cervical lesions of Mexican women.
Juárez-González K, Paredes-Cervantes V, Gordillo-Rodríguez S, González-Guzmán S, Moncayo-Valencia X, Méndez-Martínez R, García-Carrancá A, Martínez-Ezquerro JD, Rivas-Ruiz R, Sánchez-Suárez P, Álvarez-Sandoval P, Padilla-Arrieta P, Martínez-Salazar M, Vázquez-Vega S
Arch Virol 2020 Nov;165(11):2633-2640. Epub 2020 Aug 18 doi: 10.1007/s00705-020-04771-8. PMID: 32812092
Lorlatinib in patients with ALK-positive non-small-cell lung cancer: results from a global phase 2 study.
Solomon BJ, Besse B, Bauer TM, Felip E, Soo RA, Camidge DR, Chiari R, Bearz A, Lin CC, Gadgeel SM, Riely GJ, Tan EH, Seto T, James LP, Clancy JS, Abbattista A, Martini JF, Chen J, Peltz G, Thurm H, Ou SI, Shaw AT
Lancet Oncol 2018 Dec;19(12):1654-1667. Epub 2018 Nov 6 doi: 10.1016/S1470-2045(18)30649-1. PMID: 30413378
High-grade pancreatic intraepithelial lesions: prevalence and implications in pancreatic neoplasia.
Park JR, Li F, Oza VM, Sklaw BC, Cronley KM, Wellner M, Swanson B, Krishna SG
Hepatobiliary Pancreat Dis Int 2017 Apr;16(2):202-208. doi: 10.1016/s1499-3872(16)60186-8. PMID: 28381386

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