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Central nervous system leiomyoma

MedGen UID:
232695
•Concept ID:
C1334382
•
Neoplastic Process
Synonyms: Central Nervous System Leiomyoma; central nervous system leiomyoma; Leiomyoma of Central Nervous System; leiomyoma of central nervous system; Leiomyoma of CNS; leiomyoma of CNS; Leiomyoma of the Central Nervous System; leiomyoma of the central nervous system; Leiomyoma of the CNS; leiomyoma of the CNS
 
Monarch Initiative: MONDO:0003287

Definition

A benign smooth muscle neoplasm arising from the central nervous system. It is characterized by the presence of intersecting fascicles composed of spindle cells that often lack mitotic activity. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCentral nervous system leiomyoma

Professional guidelines

PubMed

The current place of medical therapy in uterine fibroid management.
Donnez J, Donnez O, Dolmans MM
Best Pract Res Clin Obstet Gynaecol 2018 Jan;46:57-65. Epub 2017 Oct 22 doi: 10.1016/j.bpobgyn.2017.10.008. PMID: 29169896
Integrated cone-beam CT and fluoroscopic navigation in treatment of head and neck vascular malformations and tumors.
Nesbit GM, Nesbit EG, Hamilton BE
J Neurointerv Surg 2011 Jun;3(2):186-90. Epub 2010 Dec 16 doi: 10.1136/jnis.2010.003376. PMID: 21990816

Recent clinical studies

Etiology

The dural angioleiomyoma harbors frequent GJA4 mutation and a distinct DNA methylation profile.
Tauziède-Espariat A, Pierre T, Wassef M, Castel D, Riant F, Grill J, Roux A, Pallud J, Dezamis E, Bresson D, Benichi S, Blauwblomme T, Benzohra D, Gauchotte G, Pouget C, Colnat-Coulbois S, Mokhtari K, Balleyguier C, Larousserie F, Dangouloff-Ros V, Boddaert N, Debily MA, Hasty L, Polivka M, Adle-Biassette H, Métais A, Lechapt E, Chrétien F, Sahm F, Sievers P, Varlet P; RENOCLIP-LOC
Acta Neuropathol Commun 2022 May 31;10(1):81. doi: 10.1186/s40478-022-01384-x. PMID: 35642047Free PMC Article
Depressive symptoms and risk of uterine leiomyomata.
Wise LA, Li S, Palmer JR, Rosenberg L
Am J Obstet Gynecol 2015 May;212(5):617.e1-10. Epub 2014 Dec 13 doi: 10.1016/j.ajog.2014.12.012. PMID: 25514762Free PMC Article
Cancers in children with HIV infection.
McClain KL, Joshi VV, Murphy SB
Hematol Oncol Clin North Am 1996 Oct;10(5):1189-201. doi: 10.1016/s0889-8588(05)70393-2. PMID: 8880205
Beneficial effects of nicotine and cigarette smoking: the real, the possible and the spurious.
Baron JA
Br Med Bull 1996 Jan;52(1):58-73. doi: 10.1093/oxfordjournals.bmb.a011533. PMID: 8746297
New entities in cutaneous soft tissue tumours.
Calonje E, Fletcher CD
Pathologica 1993 Jan-Feb;85(1095):1-15. PMID: 8390634

Diagnosis

Benign metastasizing uterine leiomyoma with lymphatic and pulmonary metastases: a case report and literature review.
Tong T, Fan Q, Wang Y, Li Y
BMC Womens Health 2023 Apr 1;23(1):154. doi: 10.1186/s12905-023-02237-y. PMID: 37005604Free PMC Article
Surgical interventions for chronic pelvic pain.
Senapati S, Atashroo D, Carey E, Dassel M, Tu MF
Curr Opin Obstet Gynecol 2016 Aug;28(4):290-6. doi: 10.1097/GCO.0000000000000281. PMID: 27285959
Aromatase: Contributions to Physiology and Disease in Women and Men.
Blakemore J, Naftolin F
Physiology (Bethesda) 2016 Jul;31(4):258-69. doi: 10.1152/physiol.00054.2015. PMID: 27252161
Primary intracranial angioleiomyomas: diagnosis, treatment, and literature review.
Li D, Hao SY, Tang J, Cao XY, Lin S, Wang JM, Wu Z, Zhang LW, Zhang JT
Brain Tumor Pathol 2014 Apr;31(2):101-7. Epub 2013 May 10 doi: 10.1007/s10014-013-0150-4. PMID: 23661286
New entities in cutaneous soft tissue tumours.
Calonje E, Fletcher CD
Pathologica 1993 Jan-Feb;85(1095):1-15. PMID: 8390634

Therapy

The current place of medical therapy in uterine fibroid management.
Donnez J, Donnez O, Dolmans MM
Best Pract Res Clin Obstet Gynaecol 2018 Jan;46:57-65. Epub 2017 Oct 22 doi: 10.1016/j.bpobgyn.2017.10.008. PMID: 29169896
Aromatase: Contributions to Physiology and Disease in Women and Men.
Blakemore J, Naftolin F
Physiology (Bethesda) 2016 Jul;31(4):258-69. doi: 10.1152/physiol.00054.2015. PMID: 27252161
Peptides: Basic determinants of reproductive functions.
Celik O, Aydin S, Celik N, Yilmaz M
Peptides 2015 Oct;72:34-43. Epub 2015 Jun 12 doi: 10.1016/j.peptides.2015.05.016. PMID: 26074346
GnRH-antagonists in reproductive medicine.
Griesinger G, Felberbaum R, Diedrich K
Arch Gynecol Obstet 2005 Dec;273(2):71-8. Epub 2005 Jul 1 doi: 10.1007/s00404-005-0021-2. PMID: 15991015
Beneficial effects of nicotine and cigarette smoking: the real, the possible and the spurious.
Baron JA
Br Med Bull 1996 Jan;52(1):58-73. doi: 10.1093/oxfordjournals.bmb.a011533. PMID: 8746297

Prognosis

Benign metastasizing uterine leiomyoma with lymphatic and pulmonary metastases: a case report and literature review.
Tong T, Fan Q, Wang Y, Li Y
BMC Womens Health 2023 Apr 1;23(1):154. doi: 10.1186/s12905-023-02237-y. PMID: 37005604Free PMC Article
Primary angioleiomyoma of right frontal cranial base with intracranial and extracranial communication.
Zhang S, Wang Z, Zhang G, Ji Y, Wang Y, Xiao S
Br J Neurosurg 2023 Oct;37(5):1010-1015. Epub 2020 Oct 23 doi: 10.1080/02688697.2020.1837731. PMID: 33095082
Primary Intracranial Angioleiomyomas as Rare, Nonmalignant, and Distinct Neoplastic Entities: A Series of 8 Cases and a Literature Review.
Li CB, Xie MG, Ma JP, Wang L, Hao SY, Zhang LW, Jia W, Jia GJ, Zhang JT, Li D, Li H, Wu Z
World Neurosurg 2018 May;113:1-13. Epub 2018 Feb 7 doi: 10.1016/j.wneu.2018.01.207. PMID: 29425983
Hormonal manipulation of benign metastasizing leiomyomas: report of two cases and review of the literature.
Rivera JA, Christopoulos S, Small D, Trifiro M
J Clin Endocrinol Metab 2004 Jul;89(7):3183-8. doi: 10.1210/jc.2003-032021. PMID: 15240591
New entities in cutaneous soft tissue tumours.
Calonje E, Fletcher CD
Pathologica 1993 Jan-Feb;85(1095):1-15. PMID: 8390634

Clinical prediction guides

Benign metastasizing uterine leiomyoma with lymphatic and pulmonary metastases: a case report and literature review.
Tong T, Fan Q, Wang Y, Li Y
BMC Womens Health 2023 Apr 1;23(1):154. doi: 10.1186/s12905-023-02237-y. PMID: 37005604Free PMC Article
Primary Intracranial Angioleiomyomas as Rare, Nonmalignant, and Distinct Neoplastic Entities: A Series of 8 Cases and a Literature Review.
Li CB, Xie MG, Ma JP, Wang L, Hao SY, Zhang LW, Jia W, Jia GJ, Zhang JT, Li D, Li H, Wu Z
World Neurosurg 2018 May;113:1-13. Epub 2018 Feb 7 doi: 10.1016/j.wneu.2018.01.207. PMID: 29425983
Primary intracranial angioleiomyomas: diagnosis, treatment, and literature review.
Li D, Hao SY, Tang J, Cao XY, Lin S, Wang JM, Wu Z, Zhang LW, Zhang JT
Brain Tumor Pathol 2014 Apr;31(2):101-7. Epub 2013 May 10 doi: 10.1007/s10014-013-0150-4. PMID: 23661286
Origins of Western diseases.
Quinn M
J R Soc Med 2011 Nov;104(11):449-56. doi: 10.1258/jrsm.2011.110014. PMID: 22048676Free PMC Article
New entities in cutaneous soft tissue tumours.
Calonje E, Fletcher CD
Pathologica 1993 Jan-Feb;85(1095):1-15. PMID: 8390634

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