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Gastric tubular adenocarcinoma

MedGen UID:
234303
•Concept ID:
C1333791
•
Neoplastic Process
Synonyms: Gastric Tubular Adenocarcinoma; gastric tubular adenocarcinoma; stomach tubular adenocarcinoma; Tubular Adenocarcinoma of Stomach; tubular adenocarcinoma of stomach; Tubular Adenocarcinoma of the Stomach; tubular adenocarcinoma of the stomach; tubular stomach adenocarcinoma
 
Monarch Initiative: MONDO:0006035

Definition

A variant of gastric adenocarcinoma characterized by prominent dilated or slit-like tubules. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGastric tubular adenocarcinoma

Professional guidelines

PubMed

Treatment of gastric adenocarcinoma: A rapidly evolving landscape.
Taieb J, Bennouna J, Penault-Llorca F, Basile D, Samalin E, Zaanan A
Eur J Cancer 2023 Dec;195:113370. Epub 2023 Oct 17 doi: 10.1016/j.ejca.2023.113370. PMID: 37948843
Esophageal and Esophagogastric Junction Cancers, Version 2.2023, NCCN Clinical Practice Guidelines in Oncology.
Ajani JA, D'Amico TA, Bentrem DJ, Cooke D, Corvera C, Das P, Enzinger PC, Enzler T, Farjah F, Gerdes H, Gibson M, Grierson P, Hofstetter WL, Ilson DH, Jalal S, Keswani RN, Kim S, Kleinberg LR, Klempner S, Lacy J, Licciardi F, Ly QP, Matkowskyj KA, McNamara M, Miller A, Mukherjee S, Mulcahy MF, Outlaw D, Perry KA, Pimiento J, Poultsides GA, Reznik S, Roses RE, Strong VE, Su S, Wang HL, Wiesner G, Willett CG, Yakoub D, Yoon H, McMillian NR, Pluchino LA
J Natl Compr Canc Netw 2023 Apr;21(4):393-422. doi: 10.6004/jnccn.2023.0019. PMID: 37015332
Current treatment and recent progress in gastric cancer.
Joshi SS, Badgwell BD
CA Cancer J Clin 2021 May;71(3):264-279. Epub 2021 Feb 16 doi: 10.3322/caac.21657. PMID: 33592120Free PMC Article

Recent clinical studies

Etiology

Gastric tubular adenocarcinoma with diffuse neutrophils infiltrating: characteristics and probable treatment strategy.
Wang B, Zhu Y, Wang S, Li Z, Wang L, Rao W, Cheng N, Chen R, Ying J, Xue L
Gastric Cancer 2024 Jan;27(1):86-101. Epub 2023 Nov 29 doi: 10.1007/s10120-023-01446-6. PMID: 38019350
Endoscopic and clinicopathological features of intramucosal, histologically mixed-type, low-grade, well-differentiated gastric tubular adenocarcinoma with the potential for late-onset lymph node metastasis.
Saitoh T, Takamura A, Watanabe G
BMC Gastroenterol 2018 Dec 27;18(1):189. doi: 10.1186/s12876-018-0919-3. PMID: 30587141Free PMC Article
MicroRNA-21 induces loss of 15-hydroxyprostaglandin dehydrogenase in early gastric tubular adenocarcinoma.
Park YS, Lee JH, Jung DB, Kim HB, Jung JH, Pak S, Ryu YM, Park HJ, Park YY, Jung HY, Myung SJ
Sci Rep 2018 Dec 7;8(1):17717. doi: 10.1038/s41598-018-36139-z. PMID: 30531928Free PMC Article

Diagnosis

Gastric tubular adenocarcinoma with diffuse neutrophils infiltrating: characteristics and probable treatment strategy.
Wang B, Zhu Y, Wang S, Li Z, Wang L, Rao W, Cheng N, Chen R, Ying J, Xue L
Gastric Cancer 2024 Jan;27(1):86-101. Epub 2023 Nov 29 doi: 10.1007/s10120-023-01446-6. PMID: 38019350
The Use of Deep Learning-Based Computer Diagnostic Algorithm for Detection of Lymph Node Metastases of Gastric Adenocarcinoma.
Matsushima J, Sato T, Ohnishi T, Yoshimura Y, Mizutani H, Koto S, Ikeda JI, Kano M, Matsubara H, Hayashi H
Int J Surg Pathol 2023 Sep;31(6):975-981. Epub 2022 Jul 27 doi: 10.1177/10668969221113475. PMID: 35898183
Endoscopic and clinicopathological features of intramucosal, histologically mixed-type, low-grade, well-differentiated gastric tubular adenocarcinoma with the potential for late-onset lymph node metastasis.
Saitoh T, Takamura A, Watanabe G
BMC Gastroenterol 2018 Dec 27;18(1):189. doi: 10.1186/s12876-018-0919-3. PMID: 30587141Free PMC Article
Gastric Adenocarcinoma of the Fundic Gland Type after Endoscopic Therapy for Metachronous Gastric Cancer.
Kino H, Nakano M, Kanamori A, Suzuki T, Kaneko Y, Tsuchida C, Tsuchida K, Tominaga K, Sasai T, Yamagishi H, Imai Y, Hiraishi H
Intern Med 2018 Mar 15;57(6):795-800. Epub 2017 Dec 8 doi: 10.2169/internalmedicine.9359-17. PMID: 29225256Free PMC Article
Clinicopathological and molecular stability and methylation analyses of gastric papillary adenocarcinoma.
Uesugi N, Sugai T, Sugimoto R, Eizuka M, Fujita Y, Sato A, Osakabe M, Ishida K, Koeda K, Sasaki A, Matsumoto T
Pathology 2017 Oct;49(6):596-603. Epub 2017 Aug 19 doi: 10.1016/j.pathol.2017.07.004. PMID: 28830689

Therapy

The Use of Deep Learning-Based Computer Diagnostic Algorithm for Detection of Lymph Node Metastases of Gastric Adenocarcinoma.
Matsushima J, Sato T, Ohnishi T, Yoshimura Y, Mizutani H, Koto S, Ikeda JI, Kano M, Matsubara H, Hayashi H
Int J Surg Pathol 2023 Sep;31(6):975-981. Epub 2022 Jul 27 doi: 10.1177/10668969221113475. PMID: 35898183

Prognosis

Gastric tubular adenocarcinoma with diffuse neutrophils infiltrating: characteristics and probable treatment strategy.
Wang B, Zhu Y, Wang S, Li Z, Wang L, Rao W, Cheng N, Chen R, Ying J, Xue L
Gastric Cancer 2024 Jan;27(1):86-101. Epub 2023 Nov 29 doi: 10.1007/s10120-023-01446-6. PMID: 38019350
A case of primary gastric small cell carcinoma with a rare pattern of lymph node metastasis.
Takeuchi H, Futamata K, Maeshima A, Hirose S, Shimada A, Kawaguchi Y, Tokuyama J, Osumi K, Kishi S, Hojo T, Kim S, Wada N, Oishi T, Isobe Y, Ikeuchi S, Kubochi K, Matsumoto S
Int J Gastrointest Cancer 2005;36(2):99-104. doi: 10.1385/IJGC:36:2:99. PMID: 16648660

Clinical prediction guides

Expression of TGF-β1 in Gastrointestinal Stromal Tumor (GIST) and the Occurrence of Frequent Desmoplasia.
Mochizuki K, Oishi N, Tahara I, Inoue T, Kondo T
Appl Immunohistochem Mol Morphol 2024 May-Jun 01;32(5):229-232. Epub 2024 Apr 8 doi: 10.1097/PAI.0000000000001196. PMID: 38584487
Endoscopic and clinicopathological features of intramucosal, histologically mixed-type, low-grade, well-differentiated gastric tubular adenocarcinoma with the potential for late-onset lymph node metastasis.
Saitoh T, Takamura A, Watanabe G
BMC Gastroenterol 2018 Dec 27;18(1):189. doi: 10.1186/s12876-018-0919-3. PMID: 30587141Free PMC Article
MicroRNA-21 induces loss of 15-hydroxyprostaglandin dehydrogenase in early gastric tubular adenocarcinoma.
Park YS, Lee JH, Jung DB, Kim HB, Jung JH, Pak S, Ryu YM, Park HJ, Park YY, Jung HY, Myung SJ
Sci Rep 2018 Dec 7;8(1):17717. doi: 10.1038/s41598-018-36139-z. PMID: 30531928Free PMC Article
Crohn enteritis-associated small bowel adenocarcinomas exhibit gastric differentiation.
Whitcomb E, Liu X, Xiao SY
Hum Pathol 2014 Feb;45(2):359-67. Epub 2013 Oct 3 doi: 10.1016/j.humpath.2013.09.014. PMID: 24331840
Study of Sonic hedgehog signaling pathway related molecules in gastric carcinoma.
Ma XL, Sun HJ, Wang YS, Huang SH, Xie JW, Zhang HW
World J Gastroenterol 2006 Jul 7;12(25):3965-9. doi: 10.3748/wjg.v12.i25.3965. PMID: 16810741Free PMC Article

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