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Recurrent Childhood Optic Nerve Glioma

MedGen UID:
234589
•Concept ID:
C1370943
•
Neoplastic Process
Synonym: Recurrent Pediatric Optic Nerve Glioma

Definition

The reemergence of optic nerve glioma in childhood after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Childhood Optic Nerve Glioma

Professional guidelines

PubMed

Current and emerging treatment strategies for children with progressive chiasmatic-hypothalamic glioma diagnosed as infants: a web-based survey.
Azizi AA, Schouten-van Meeteren AYN
J Neurooncol 2018 Jan;136(1):127-134. Epub 2017 Oct 25 doi: 10.1007/s11060-017-2630-6. PMID: 29071540Free PMC Article
Neuroophthalmological management of optic pathway gliomas.
Lee AG
Neurosurg Focus 2007;23(5):E1. doi: 10.3171/FOC-07/11/E1. PMID: 18004957
Management of chiasmal and hypothalamic gliomas of infancy and childhood with chemotherapy.
Petronio J, Edwards MS, Prados M, Freyberger S, Rabbitt J, Silver P, Levin VA
J Neurosurg 1991 May;74(5):701-8. doi: 10.3171/jns.1991.74.5.0701. PMID: 1901597

Recent clinical studies

Etiology

Very long-term outcomes of pediatric patients treated for optic pathway gliomas: A longitudinal cohort study.
Morin A, Allodji R, Kariyawasam D, Touraine P, Puget S, Beccaria K, De Carli E, Kieffer V, Rivollet S, Abbou S, Fayech C, Souchard V, Dufour C, De Vathaire F, Bolle S, Grill J, Fresneau B
Neuro Oncol 2024 Jul 5;26(7):1310-1324. doi: 10.1093/neuonc/noae045. PMID: 38465768Free PMC Article
Recurrent contracted sockets treated with personalized, three-dimensionally printed conformers and buccal grafts.
Groot A, Remmers JS, Kloos RJ, Saeed P, Hartong DT
Eur J Ophthalmol 2022 Jan;32(1):717-724. Epub 2021 Mar 11 doi: 10.1177/11206721211000013. PMID: 33706571Free PMC Article
Optic pathway-hypothalamic glioma hemorrhage: a series of 9 patients and review of the literature.
van Baarsen K, Roth J, Serova N, Packer RJ, Shofty B, Thomale UW, Cinalli G, Toledano H, Michowiz S, Constantini S
J Neurosurg 2018 Dec 1;129(6):1407-1415. doi: 10.3171/2017.8.JNS163085. PMID: 29424646
Cerebral peduncle tumor ablated by novel 3-mm laser tip.
Xu DS, Rosenfeld A, Ponce FA, Nakaji P, Bhardwaj RD
Stereotact Funct Neurosurg 2015;93(1):38-41. Epub 2015 Jan 31 doi: 10.1159/000368907. PMID: 25662091
Spontaneous regression of low-grade astrocytomas in childhood.
Schmandt SM, Packer RJ, Vezina LG, Jane J
Pediatr Neurosurg 2000 Mar;32(3):132-6. doi: 10.1159/000028917. PMID: 10867559

Diagnosis

Very long-term outcomes of pediatric patients treated for optic pathway gliomas: A longitudinal cohort study.
Morin A, Allodji R, Kariyawasam D, Touraine P, Puget S, Beccaria K, De Carli E, Kieffer V, Rivollet S, Abbou S, Fayech C, Souchard V, Dufour C, De Vathaire F, Bolle S, Grill J, Fresneau B
Neuro Oncol 2024 Jul 5;26(7):1310-1324. doi: 10.1093/neuonc/noae045. PMID: 38465768Free PMC Article
Cranio-Orbital Approach for Single-Stage En Bloc Resection of Optic Nerve Glioma: Technical Note.
Fredrickson VL, Agnoletto GJ, Hollon TC, Kundu B, Mortimer VR, Couldwell WT
Oper Neurosurg (Hagerstown) 2022 Feb 1;22(2):e95-e99. doi: 10.1227/ONS.0000000000000027. PMID: 35007223
Optic pathway-hypothalamic glioma hemorrhage: a series of 9 patients and review of the literature.
van Baarsen K, Roth J, Serova N, Packer RJ, Shofty B, Thomale UW, Cinalli G, Toledano H, Michowiz S, Constantini S
J Neurosurg 2018 Dec 1;129(6):1407-1415. doi: 10.3171/2017.8.JNS163085. PMID: 29424646
Separation of outer retinal layers secondary to selumetinib.
Avery RA, Trimboli-Heidler C, Kilburn LB
J AAPOS 2016 Jun;20(3):268-71. Epub 2016 Apr 21 doi: 10.1016/j.jaapos.2016.01.012. PMID: 27108842Free PMC Article
Spontaneous regression of low-grade astrocytomas in childhood.
Schmandt SM, Packer RJ, Vezina LG, Jane J
Pediatr Neurosurg 2000 Mar;32(3):132-6. doi: 10.1159/000028917. PMID: 10867559

Therapy

A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study.
Fangusaro J, Onar-Thomas A, Poussaint TY, Wu S, Ligon AH, Lindeman N, Campagne O, Banerjee A, Gururangan S, Kilburn LB, Goldman S, Qaddoumi I, Baxter P, Vezina G, Bregman C, Patay Z, Jones JY, Stewart CF, Fisher MJ, Doyle LA, Smith M, Dunkel IJ, Fouladi M
Neuro Oncol 2021 Oct 1;23(10):1777-1788. doi: 10.1093/neuonc/noab047. PMID: 33631016Free PMC Article
Separation of outer retinal layers secondary to selumetinib.
Avery RA, Trimboli-Heidler C, Kilburn LB
J AAPOS 2016 Jun;20(3):268-71. Epub 2016 Apr 21 doi: 10.1016/j.jaapos.2016.01.012. PMID: 27108842Free PMC Article
Cerebral peduncle tumor ablated by novel 3-mm laser tip.
Xu DS, Rosenfeld A, Ponce FA, Nakaji P, Bhardwaj RD
Stereotact Funct Neurosurg 2015;93(1):38-41. Epub 2015 Jan 31 doi: 10.1159/000368907. PMID: 25662091
Primary CNS lymphoma arising in the region of the optic nerve presenting as loss of vision: 2 case reports, including a patient with a massive intracerebral hemorrhage.
Matsuyama J, Ichikawa M, Oikawa T, Sato T, Kishida Y, Oda K, Maeda T, Yamada M, Kuromi Y, Matsumoto Y, Ando H, Sakuma J, Saito K
Brain Tumor Pathol 2014 Jul;31(3):222-8. Epub 2013 Sep 3 doi: 10.1007/s10014-013-0159-8. PMID: 23999767
Neuroophthalmological management of optic pathway gliomas.
Lee AG
Neurosurg Focus 2007;23(5):E1. doi: 10.3171/FOC-07/11/E1. PMID: 18004957

Prognosis

Very long-term outcomes of pediatric patients treated for optic pathway gliomas: A longitudinal cohort study.
Morin A, Allodji R, Kariyawasam D, Touraine P, Puget S, Beccaria K, De Carli E, Kieffer V, Rivollet S, Abbou S, Fayech C, Souchard V, Dufour C, De Vathaire F, Bolle S, Grill J, Fresneau B
Neuro Oncol 2024 Jul 5;26(7):1310-1324. doi: 10.1093/neuonc/noae045. PMID: 38465768Free PMC Article
A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study.
Fangusaro J, Onar-Thomas A, Poussaint TY, Wu S, Ligon AH, Lindeman N, Campagne O, Banerjee A, Gururangan S, Kilburn LB, Goldman S, Qaddoumi I, Baxter P, Vezina G, Bregman C, Patay Z, Jones JY, Stewart CF, Fisher MJ, Doyle LA, Smith M, Dunkel IJ, Fouladi M
Neuro Oncol 2021 Oct 1;23(10):1777-1788. doi: 10.1093/neuonc/noab047. PMID: 33631016Free PMC Article
Optic pathway-hypothalamic glioma hemorrhage: a series of 9 patients and review of the literature.
van Baarsen K, Roth J, Serova N, Packer RJ, Shofty B, Thomale UW, Cinalli G, Toledano H, Michowiz S, Constantini S
J Neurosurg 2018 Dec 1;129(6):1407-1415. doi: 10.3171/2017.8.JNS163085. PMID: 29424646
Spontaneous regression of low-grade astrocytomas in childhood.
Schmandt SM, Packer RJ, Vezina LG, Jane J
Pediatr Neurosurg 2000 Mar;32(3):132-6. doi: 10.1159/000028917. PMID: 10867559
Repeat megavoltage irradiation of pituitary and suprasellar tumors.
Flickinger JC, Deutsch M, Lunsford LD
Int J Radiat Oncol Biol Phys 1989 Jul;17(1):171-5. doi: 10.1016/0360-3016(89)90385-4. PMID: 2501242

Clinical prediction guides

Very long-term outcomes of pediatric patients treated for optic pathway gliomas: A longitudinal cohort study.
Morin A, Allodji R, Kariyawasam D, Touraine P, Puget S, Beccaria K, De Carli E, Kieffer V, Rivollet S, Abbou S, Fayech C, Souchard V, Dufour C, De Vathaire F, Bolle S, Grill J, Fresneau B
Neuro Oncol 2024 Jul 5;26(7):1310-1324. doi: 10.1093/neuonc/noae045. PMID: 38465768Free PMC Article
Pediatric Optic Pathway Gliomas: A Report From Northern Greece.
Panagopoulou P, Athanasiadis D, Αnastasiou Α, Zafeiriou D, Papakonstantinou Ε
J Pediatr Hematol Oncol 2023 Nov 1;45(8):445-451. Epub 2023 Sep 9 doi: 10.1097/MPH.0000000000002753. PMID: 37696004
Re-irradiation for recurrent glioma- the NCI experience in tumor control, OAR toxicity and proposal of a novel prognostic scoring system.
Krauze AV, Peters C, Cheng J, Ning H, Mackey M, Rowe L, Cooley-Zgela T, Smart DD, Camphausen K
Radiat Oncol 2017 Nov 29;12(1):191. doi: 10.1186/s13014-017-0930-9. PMID: 29187219Free PMC Article
Prechiasmatic transection of the optic nerve in optic nerve glioma: technical description and surgical outcome.
Borghei-Razavi H, Shibao S, Schick U
Neurosurg Rev 2017 Jan;40(1):135-141. Epub 2016 May 26 doi: 10.1007/s10143-016-0747-2. PMID: 27230830
Accuracy of MRI in defining tumor-free margin in optic nerve glioma surgery.
Spicer GJ, Kazim M, Glass LR, Harris GJ, Miller NR, Rootman J, Sullivan TJ
Ophthalmic Plast Reconstr Surg 2013 Jul-Aug;29(4):277-80. doi: 10.1097/IOP.0b013e318291658e. PMID: 23715516

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