U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Salivary Gland Cystadenoma

MedGen UID:
234767
Concept ID:
C1335898
Neoplastic Process

Definition

An uncommon benign epithelial tumor, characterized by predominantly unicystic or multicystic growth; there is focal intraluminal papillary proliferation of the lining epithelium. Nearly half occur in the parotid gland. In the minor salivary glands, women are affected more than men. In the major salivary glands, cystadenomas present as slowly enlarging, asymptomatic masses that may be slightly compressible. Cystadenocarcinoma is the malignant counterpart. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSalivary Gland Cystadenoma

Professional guidelines

PubMed

García RF
Int J Oral Surg 1974;3(5):330-4. doi: 10.1016/s0300-9785(74)80073-6. PMID: 4370963
Healey WV, Perzin KH, Smith L
Cancer 1970 Aug;26(2):368-88. doi: 10.1002/1097-0142(197008)26:2<368::aid-cncr2820260219>3.0.co;2-k. PMID: 5451215
ABBISS JW, PIERSON JC
Del State Med J 1954 Oct;26(10):257-60. PMID: 13210035

Recent clinical studies

Etiology

Agaimy A
Surg Pathol Clin 2021 Mar;14(1):53-65. Epub 2020 Dec 15 doi: 10.1016/j.path.2020.09.007. PMID: 33526223
Israel Y, Rachmiel A, Ziv G, Nagler R
Anticancer Res 2016 Aug;36(8):4151-4. PMID: 27466524
Patel DK, Morton RP
Acta Otolaryngol 2016;136(1):83-6. Epub 2015 Oct 8 doi: 10.3109/00016489.2015.1081276. PMID: 26449442
Brandt A, Schaefer IM, Rustenbeck HH, Matthias C, Laskawi R
Oral Maxillofac Surg 2013 Dec;17(4):307-9. Epub 2013 Jan 11 doi: 10.1007/s10006-012-0385-y. PMID: 23306947Free PMC Article
Alexis JB, Dembrow V
J Oral Maxillofac Surg 1995 Jan;53(1):70-2; discussion 73. doi: 10.1016/0278-2391(95)90506-5. PMID: 7799126

Diagnosis

Agaimy A
Surg Pathol Clin 2021 Mar;14(1):53-65. Epub 2020 Dec 15 doi: 10.1016/j.path.2020.09.007. PMID: 33526223
Bishop JA, Thompson LDR
Surg Pathol Clin 2021 Mar;14(1):17-24. doi: 10.1016/j.path.2020.09.004. PMID: 33526220
Stewart KE, Bannon R, Bannister M
Ann R Coll Surg Engl 2021 Jan;103(1):47-52. Epub 2020 Sep 24 doi: 10.1308/rcsann.2020.0194. PMID: 32969265Free PMC Article
Alexis JB, Dembrow V
J Oral Maxillofac Surg 1995 Jan;53(1):70-2; discussion 73. doi: 10.1016/0278-2391(95)90506-5. PMID: 7799126
Friedman EW, Schwartz AE
CA Cancer J Clin 1974 Sep-Oct;24(5):266-73. doi: 10.3322/canjclin.24.5.266. PMID: 4371314

Therapy

Mantsopoulos K, Koch M, Goncalves M, Iro H
Oral Oncol 2018 Jul;82:176-180. Epub 2018 Jun 1 doi: 10.1016/j.oraloncology.2018.05.022. PMID: 29909894
Halbritter SA, Altermatt HJ, Caversaccio M, Bornstein MM
Quintessence Int 2009 Feb;40(2):167-9. PMID: 19169449
Gaissert HA, Mark EJ
Cancer Control 2006 Oct;13(4):286-94. doi: 10.1177/107327480601300406. PMID: 17075566
Martins C, Fonseca I, Félix A, Roque L, Soares J
J Surg Oncol 1995 Dec;60(4):232-7. doi: 10.1002/jso.2930600404. PMID: 8551731
Yoshimura Y, Tawara K, Yoshigi J, Nagaoka S
J Oral Maxillofac Surg 1995 Apr;53(4):448-53. doi: 10.1016/0278-2391(95)90722-x. PMID: 7699501

Prognosis

Agaimy A
Surg Pathol Clin 2021 Mar;14(1):53-65. Epub 2020 Dec 15 doi: 10.1016/j.path.2020.09.007. PMID: 33526223
Bishop JA, Thompson LDR
Surg Pathol Clin 2021 Mar;14(1):17-24. doi: 10.1016/j.path.2020.09.004. PMID: 33526220
Witt RL, Nicolai P
Adv Otorhinolaryngol 2016;78:63-70. Epub 2016 Apr 12 doi: 10.1159/000442126. PMID: 27093568
Alexis JB, Dembrow V
J Oral Maxillofac Surg 1995 Jan;53(1):70-2; discussion 73. doi: 10.1016/0278-2391(95)90506-5. PMID: 7799126
Puts JJ, Voorsmit RA, van Haelst UJ
J Maxillofac Surg 1984 Apr;12(2):90-4. doi: 10.1016/s0301-0503(84)80218-0. PMID: 6585460

Clinical prediction guides

Fatima S, Ahmed A, Suleman S, Din NU
Ann Diagn Pathol 2023 Dec;67:152220. Epub 2023 Oct 28 doi: 10.1016/j.anndiagpath.2023.152220. PMID: 37924657
Malik V, Dixit M, Sharma S, Jain A, Dhankad A, Mohanty SK
Pathol Res Pract 2023 Nov;251:154884. Epub 2023 Oct 11 doi: 10.1016/j.prp.2023.154884. PMID: 37913638
Hellquist H, Paiva-Correia A, Vander Poorten V, Quer M, Hernandez-Prera JC, Andreasen S, Zbären P, Skalova A, Rinaldo A, Ferlito A
Adv Ther 2019 Aug;36(8):1950-1974. Epub 2019 Jun 17 doi: 10.1007/s12325-019-01007-3. PMID: 31209701Free PMC Article
Witt RL, Nicolai P
Adv Otorhinolaryngol 2016;78:63-70. Epub 2016 Apr 12 doi: 10.1159/000442126. PMID: 27093568
Nordkvist A, Mark J, Dahlenfors R, Bende M, Stenman G
Cancer Genet Cytogenet 1994 Sep;76(2):129-35. doi: 10.1016/0165-4608(94)90463-4. PMID: 7923062

Recent systematic reviews

Stewart KE, Bannon R, Bannister M
Ann R Coll Surg Engl 2021 Jan;103(1):47-52. Epub 2020 Sep 24 doi: 10.1308/rcsann.2020.0194. PMID: 32969265Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...