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Central auditory dysfunction

MedGen UID:
2492
•Concept ID:
C0004303
•
Disease or Syndrome
Synonyms: Auditory Disease, Central; Auditory Diseases, Central; Auditory Dysfunction, Central; Auditory Pathway Disorders, Central; Central Auditory Disease; Central Auditory Diseases; Central Auditory Dysfunction; Central Auditory Pathway Disorders; Dysfunction, Central Auditory; Dysfunctions, Central Auditory
SNOMED CT: Central auditory dysfunction (68467004)

Definition

Disorders of hearing or auditory perception due to pathological processes of the AUDITORY PATHWAYS in the CENTRAL NERVOUS SYSTEM. These include CENTRAL HEARING LOSS and AUDITORY PERCEPTUAL DISORDERS. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCentral auditory dysfunction

Professional guidelines

PubMed

The natural history, clinical outcomes, and genotype-phenotype relationship of otoferlin-related hearing loss: a systematic, quantitative literature review.
Ford CL, Riggs WJ, Quigley T, Keifer OP Jr, Whitton JP, Valayannopoulos V
Hum Genet 2023 Oct;142(10):1429-1449. Epub 2023 Sep 7 doi: 10.1007/s00439-023-02595-5. PMID: 37679651Free PMC Article
Advances in Understanding, Diagnosis, and Treatment of Tinnitus.
Tang D, Li H, Chen L
Adv Exp Med Biol 2019;1130:109-128. doi: 10.1007/978-981-13-6123-4_7. PMID: 30915704
Auditory Neuropathy/Dys-Synchrony Disorder: Diagnosis and Management.
Hood LJ
Otolaryngol Clin North Am 2015 Dec;48(6):1027-40. Epub 2015 Aug 18 doi: 10.1016/j.otc.2015.06.006. PMID: 26296649

Recent clinical studies

Etiology

Hearing loss and Alzheimer's disease: A Review.
Ralli M, Gilardi A, Stadio AD, Severini C, Salzano FA, Greco A, Vincentiis M
Int Tinnitus J 2019 Sep 4;23(2):79-85. doi: 10.5935/0946-5448.20190014. PMID: 32009339
Auditory system dysfunction in Alzheimer disease and its prodromal states: A review.
Swords GM, Nguyen LT, Mudar RA, Llano DA
Ageing Res Rev 2018 Jul;44:49-59. Epub 2018 Apr 6 doi: 10.1016/j.arr.2018.04.001. PMID: 29630950Free PMC Article
Implications of blast exposure for central auditory function: a review.
Gallun FJ, Lewis MS, Folmer RL, Diedesch AC, Kubli LR, McDermott DJ, Walden TC, Fausti SA, Lew HL, Leek MR
J Rehabil Res Dev 2012;49(7):1059-74. doi: 10.1682/jrrd.2010.09.0166. PMID: 23341279
Central auditory dysfunction associated with exposure to a mixture of solvents.
Fuente A, McPherson B, Hickson L
Int J Audiol 2011 Dec;50(12):857-65. Epub 2011 Sep 22 doi: 10.3109/14992027.2011.605805. PMID: 21936752
Dichotic speech tests.
Hällgren M, Johansson M, Larsby B, Arlinger S
Scand Audiol Suppl 1998;49:35-9. doi: 10.1080/010503998420630. PMID: 10209775

Diagnosis

Auditory system dysfunction in Alzheimer disease and its prodromal states: A review.
Swords GM, Nguyen LT, Mudar RA, Llano DA
Ageing Res Rev 2018 Jul;44:49-59. Epub 2018 Apr 6 doi: 10.1016/j.arr.2018.04.001. PMID: 29630950Free PMC Article
Central auditory processing disorders in children and adults.
Bellis TJ, Bellis JD
Handb Clin Neurol 2015;129:537-56. doi: 10.1016/B978-0-444-62630-1.00030-5. PMID: 25726289
Sources of pathology underlying listening disorders in children.
Moore DR
Int J Psychophysiol 2015 Feb;95(2):125-34. Epub 2014 Jul 31 doi: 10.1016/j.ijpsycho.2014.07.006. PMID: 25086259
Implications of blast exposure for central auditory function: a review.
Gallun FJ, Lewis MS, Folmer RL, Diedesch AC, Kubli LR, McDermott DJ, Walden TC, Fausti SA, Lew HL, Leek MR
J Rehabil Res Dev 2012;49(7):1059-74. doi: 10.1682/jrrd.2010.09.0166. PMID: 23341279
Central auditory dysfunction in schizophrenia as revealed by the mismatch negativity (MMN) and its magnetic equivalent MMNm: a review.
Näätänen R, Kähkönen S
Int J Neuropsychopharmacol 2009 Feb;12(1):125-35. Epub 2008 Sep 4 doi: 10.1017/S1461145708009322. PMID: 18771603

Therapy

Jet fuel exposure and auditory outcomes in Australian air force personnel.
Fuente A, Hickson L, Morata TC, Williams W, Khan A, Fuentes-Lopez E
BMC Public Health 2019 May 31;19(1):675. doi: 10.1186/s12889-019-7038-0. PMID: 31151392Free PMC Article
The Adverse Effects of Heavy Metals with and without Noise Exposure on the Human Peripheral and Central Auditory System: A Literature Review.
Castellanos MJ, Fuente A
Int J Environ Res Public Health 2016 Dec 9;13(12) doi: 10.3390/ijerph13121223. PMID: 27941700Free PMC Article
Central auditory dysfunction associated with exposure to a mixture of solvents.
Fuente A, McPherson B, Hickson L
Int J Audiol 2011 Dec;50(12):857-65. Epub 2011 Sep 22 doi: 10.3109/14992027.2011.605805. PMID: 21936752
Peripheral and central auditory dysfunction induced by occupational exposure to organic solvents.
Fuente A, Slade MD, Taylor T, Morata TC, Keith RW, Sparer J, Rabinowitz PM
J Occup Environ Med 2009 Oct;51(10):1202-11. doi: 10.1097/JOM.0b013e3181bae17c. PMID: 19786896
Dichotic speech tests.
Hällgren M, Johansson M, Larsby B, Arlinger S
Scand Audiol Suppl 1998;49:35-9. doi: 10.1080/010503998420630. PMID: 10209775

Prognosis

Central auditory function of deafness genes.
Willaredt MA, Ebbers L, Nothwang HG
Hear Res 2014 Jun;312:9-20. Epub 2014 Feb 22 doi: 10.1016/j.heares.2014.02.004. PMID: 24566090
Implications of blast exposure for central auditory function: a review.
Gallun FJ, Lewis MS, Folmer RL, Diedesch AC, Kubli LR, McDermott DJ, Walden TC, Fausti SA, Lew HL, Leek MR
J Rehabil Res Dev 2012;49(7):1059-74. doi: 10.1682/jrrd.2010.09.0166. PMID: 23341279
Neural network modeling of central auditory dysfunction in Alzheimer's disease.
Krishnamurti S, Drake L, King J
Neural Netw 2011 Aug;24(6):646-51. Epub 2011 Mar 5 doi: 10.1016/j.neunet.2011.02.010. PMID: 21441013
The mismatch negativity in evaluating central auditory dysfunction in dyslexia.
Kujala T, Näätänen R
Neurosci Biobehav Rev 2001 Aug;25(6):535-43. doi: 10.1016/s0149-7634(01)00032-x. PMID: 11595273
Central auditory dysfunction, cognitive dysfunction, and dementia in older people.
Gates GA, Cobb JL, Linn RT, Rees T, Wolf PA, D'Agostino RB
Arch Otolaryngol Head Neck Surg 1996 Feb;122(2):161-7. doi: 10.1001/archotol.1996.01890140047010. PMID: 8630210

Clinical prediction guides

Auditory Agnosia for Environmental Sounds in Alzheimer's Disease: Not Hearing and Not Listening?
Coebergh JAF, McDowell S, van Woerkom TCAM, Koopman JP, Mulder J, Bruijn SFTM
J Alzheimers Dis 2020;73(4):1407-1419. doi: 10.3233/JAD-190431. PMID: 31958091
No association between plasma adiponectin levels and central auditory function in adults.
Hwang JH, Tseng FY, Liu TC, Yang WS
Metab Brain Dis 2015 Feb;30(1):191-6. Epub 2014 Aug 10 doi: 10.1007/s11011-014-9597-1. PMID: 25108594
Central auditory function of deafness genes.
Willaredt MA, Ebbers L, Nothwang HG
Hear Res 2014 Jun;312:9-20. Epub 2014 Feb 22 doi: 10.1016/j.heares.2014.02.004. PMID: 24566090
Implications of blast exposure for central auditory function: a review.
Gallun FJ, Lewis MS, Folmer RL, Diedesch AC, Kubli LR, McDermott DJ, Walden TC, Fausti SA, Lew HL, Leek MR
J Rehabil Res Dev 2012;49(7):1059-74. doi: 10.1682/jrrd.2010.09.0166. PMID: 23341279
Executive dysfunction and presbycusis in older persons with and without memory loss and dementia.
Gates GA, Gibbons LE, McCurry SM, Crane PK, Feeney MP, Larson EB
Cogn Behav Neurol 2010 Dec;23(4):218-23. doi: 10.1097/WNN.0b013e3181d748d7. PMID: 21150347Free PMC Article

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