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Benign neoplasm of lower jaw bone

MedGen UID:
2572
•Concept ID:
C0004994
•
Neoplastic Process
Synonyms: Benign Neoplasm of Lower Jaw Bone; benign neoplasm of lower jaw bone; Benign neoplasm of mandible; Benign Neoplasm of Mandible; bone of lower jaw benign neoplasm
SNOMED CT: Benign neoplasm of mandible (92208007); Benign neoplasm of lower jaw bone (92208007)
 
Monarch Initiative: MONDO:0021522

Definition

A non-metastasizing neoplasm that arises from the mandible. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of lower jaw bone

Professional guidelines

PubMed

Cystic Lesions of the Jaws: The Top 10 Differential Diagnoses to Ponder.
McLean AC, Vargas PA
Head Neck Pathol 2023 Mar;17(1):85-98. Epub 2023 Mar 16 doi: 10.1007/s12105-023-01525-1. PMID: 36928736Free PMC Article
Treatment of late sequelae after radiotherapy for head and neck cancer.
Strojan P, Hutcheson KA, Eisbruch A, Beitler JJ, Langendijk JA, Lee AWM, Corry J, Mendenhall WM, Smee R, Rinaldo A, Ferlito A
Cancer Treat Rev 2017 Sep;59:79-92. Epub 2017 Jul 18 doi: 10.1016/j.ctrv.2017.07.003. PMID: 28759822Free PMC Article
Medical treatment of osteoradionecrosis of the mandible by PENTOCLO: preliminary results.
Robard L, Louis MY, Blanchard D, Babin E, Delanian S
Eur Ann Otorhinolaryngol Head Neck Dis 2014 Dec;131(6):333-338. Epub 2014 Jun 30 doi: 10.1016/j.anorl.2013.11.006. PMID: 24993781

Recent clinical studies

Etiology

Benign fibrohistiocytic jaw lesions: a 48-year clinicopathologic analysis and review of the literature.
Mewar P, Foss RD
Oral Surg Oral Med Oral Pathol Oral Radiol 2023 Aug;136(2):195-210. Epub 2023 Apr 8 doi: 10.1016/j.oooo.2023.04.002. PMID: 37277279
Osteoradionecrosis of mandible bone in patients with oral cancer--associated factors and treatment outcomes.
Chen JA, Wang CC, Wong YK, Wang CP, Jiang RS, Lin JC, Chen CC, Liu SA
Head Neck 2016 May;38(5):762-8. Epub 2015 Jun 20 doi: 10.1002/hed.23949. PMID: 25521838
Osteosarcomas of the mandible: are they different from other tumor sites?
Thariat J, Julieron M, Brouchet A, Italiano A, Schouman T, Marcy PY, Odin G, Lacout A, Dassonville O, Peyrottes-Birstwisles I, Miller R, Thyss A, Isambert N
Crit Rev Oncol Hematol 2012 Jun;82(3):280-95. Epub 2011 Aug 24 doi: 10.1016/j.critrevonc.2011.07.001. PMID: 21868246
Schwannoma of the mandible.
Belli E, Becelli R, Matteini C, Iannetti G
J Craniofac Surg 1997 Sep;8(5):413-6. doi: 10.1097/00001665-199708050-00015. PMID: 9482084
Clinical and radiological features of odontogenic myxoma of the jaws.
Kaffe I, Naor H, Buchner A
Dentomaxillofac Radiol 1997 Sep;26(5):299-303. doi: 10.1038/sj.dmfr.4600261. PMID: 9482003

Diagnosis

Management of osteosarcoma of the head and neck.
Sharin F, Pai A, Mair M
Curr Opin Otolaryngol Head Neck Surg 2023 Aug 1;31(4):269-275. Epub 2023 May 3 doi: 10.1097/MOO.0000000000000900. PMID: 37144500
Unicystic Ameloblastoma of Mandible: A Case Report.
Rayamajhi S, Shrestha S, Shakya S, Bhandari S, Twayana AR, Shahi K
JNMA J Nepal Med Assoc 2022 Jul 1;60(251):657-660. doi: 10.31729/jnma.7566. PMID: 36705195Free PMC Article
Benign Jaw Lesions.
Gohel A, Villa A, Sakai O
Dent Clin North Am 2016 Jan;60(1):125-41. doi: 10.1016/j.cden.2015.08.005. PMID: 26614952
Lesions of the Jaw.
Mosier KM
Semin Ultrasound CT MR 2015 Oct;36(5):444-50. Epub 2015 Aug 28 doi: 10.1053/j.sult.2015.08.003. PMID: 26589698
A radiological approach to benign and malignant lesions of the mandible.
Harmon M, Arrigan M, Toner M, O'Keeffe SA
Clin Radiol 2015 Apr;70(4):335-50. Epub 2015 Jan 2 doi: 10.1016/j.crad.2014.10.011. PMID: 25559378

Therapy

Osteoradionecrosis: Exposing the Evidence Not the Bone.
Frankart AJ, Frankart MJ, Cervenka B, Tang AL, Krishnan DG, Takiar V
Int J Radiat Oncol Biol Phys 2021 Apr 1;109(5):1206-1218. Epub 2021 Jan 4 doi: 10.1016/j.ijrobp.2020.12.043. PMID: 33412258
Treatment of late sequelae after radiotherapy for head and neck cancer.
Strojan P, Hutcheson KA, Eisbruch A, Beitler JJ, Langendijk JA, Lee AWM, Corry J, Mendenhall WM, Smee R, Rinaldo A, Ferlito A
Cancer Treat Rev 2017 Sep;59:79-92. Epub 2017 Jul 18 doi: 10.1016/j.ctrv.2017.07.003. PMID: 28759822Free PMC Article
A new classification for mandibular defects after oncological resection.
Brown JS, Barry C, Ho M, Shaw R
Lancet Oncol 2016 Jan;17(1):e23-30. Epub 2015 Dec 23 doi: 10.1016/S1470-2045(15)00310-1. PMID: 26758757
Numb chin syndrome: a rare and often overlooked symptom.
Assaf AT, Jürgens TP, Benecke AW, Riecke B, Blessmann M, Zrnc TA, Much CC, Heiland M, Friedrich RE
J Oral Facial Pain Headache 2014 Winter;28(1):80-90. doi: 10.11607/jop.994. PMID: 24482791
Osteoradionecrosis.
O'Dell K, Sinha U
Oral Maxillofac Surg Clin North Am 2011 Aug;23(3):455-64. doi: 10.1016/j.coms.2011.04.011. PMID: 21798443

Prognosis

Management of osteosarcoma of the head and neck.
Sharin F, Pai A, Mair M
Curr Opin Otolaryngol Head Neck Surg 2023 Aug 1;31(4):269-275. Epub 2023 May 3 doi: 10.1097/MOO.0000000000000900. PMID: 37144500
Bone Flap Technique for Impacted Teeth Extraction and Bone Cysts Removal.
Saponaro G, Pelo S, De Angelis P, Forcione M, D'Amato G, Moro A
J Craniofac Surg 2016 Jun;27(4):1084-6. doi: 10.1097/SCS.0000000000002606. PMID: 27171951
Ameloblastoma: a clinical review and trends in management.
McClary AC, West RB, McClary AC, Pollack JR, Fischbein NJ, Holsinger CF, Sunwoo J, Colevas AD, Sirjani D
Eur Arch Otorhinolaryngol 2016 Jul;273(7):1649-61. Epub 2015 Apr 30 doi: 10.1007/s00405-015-3631-8. PMID: 25926124
Schwannoma of the mandible.
Belli E, Becelli R, Matteini C, Iannetti G
J Craniofac Surg 1997 Sep;8(5):413-6. doi: 10.1097/00001665-199708050-00015. PMID: 9482084
Peripheral ameloblastoma.
Niccoli-Filho W, Gomes Mda G, Raldi FV, Seraidarian PI
J Nihon Univ Sch Dent 1997 Mar;39(1):34-7. doi: 10.2334/josnusd1959.39.34. PMID: 9198334

Clinical prediction guides

Prospective Phase II Open-Label Randomized Controlled Trial to Compare Mandibular Preservation in Upfront Surgery With Neoadjuvant Chemotherapy Followed by Surgery in Operable Oral Cavity Cancer.
Chaukar D, Prabash K, Rane P, Patil VM, Thiagarajan S, Ghosh-Laskar S, Sharma S, Pai PS, Chaturvedi P, Pantvaidya G, Deshmukh A, Nair D, Nair S, Vaish R, Noronha V, Patil A, Arya S, D'Cruz A
J Clin Oncol 2022 Jan 20;40(3):272-281. Epub 2021 Dec 6 doi: 10.1200/JCO.21.00179. PMID: 34871101
Odontogenic keratocyst of the mandible: A case report and literature review.
Polak K, Jędrusik-Pawłowska M, Drozdzowska B, Morawiec T
Dent Med Probl 2019 Oct-Dec;56(4):433-436. doi: 10.17219/dmp/110682. PMID: 31689015
Mandibular lymphoma.
Vo Quang S, Sicard L, Samama M, Benslama L, Goudot P
J Stomatol Oral Maxillofac Surg 2018 Feb;119(1):49-51. Epub 2017 Oct 9 doi: 10.1016/j.jormas.2017.10.004. PMID: 29024750
Clinicopathological characteristics of desmoplastic ameloblastoma: A systematic review.
Anand R, Sarode GS, Sarode SC, Reddy M, Unadkat HV, Mushtaq S, Deshmukh R, Choudhary S, Gupta N, Ganjre AP, Patil S
J Investig Clin Dent 2018 Feb;9(1) Epub 2017 Jul 14 doi: 10.1111/jicd.12282. PMID: 28707772
Clinical and radiological features of odontogenic myxoma of the jaws.
Kaffe I, Naor H, Buchner A
Dentomaxillofac Radiol 1997 Sep;26(5):299-303. doi: 10.1038/sj.dmfr.4600261. PMID: 9482003

Recent systematic reviews

Papilliferous Keratoameloblastoma: Systematic review.
Sachdev SS, Chettiankandy TJ, Adhane YB, Sardar MA, Trimukhe A, Jain R
Sultan Qaboos Univ Med J 2023 Aug;23(3):288-296. Epub 2023 Aug 28 doi: 10.18295/squmj.5.2023.021. PMID: 37655071Free PMC Article
Osteoradionecrosis: Exposing the Evidence Not the Bone.
Frankart AJ, Frankart MJ, Cervenka B, Tang AL, Krishnan DG, Takiar V
Int J Radiat Oncol Biol Phys 2021 Apr 1;109(5):1206-1218. Epub 2021 Jan 4 doi: 10.1016/j.ijrobp.2020.12.043. PMID: 33412258
Oral radiation-induced sarcomas: Systematic review.
de Souza LL, Pontes HAR, Santos-Silva AR, Fernandes LA, Batista LAL, Lopes MA, Khan W, Pontes FSC
Head Neck 2020 Sep;42(9):2660-2668. Epub 2020 Apr 28 doi: 10.1002/hed.26176. PMID: 32343457
Effect of advanced age and/or systemic medical conditions on dental implant survival: A systematic review and meta-analysis.
Schimmel M, Srinivasan M, McKenna G, Müller F
Clin Oral Implants Res 2018 Oct;29 Suppl 16:311-330. doi: 10.1111/clr.13288. PMID: 30328186
Interventions for managing medication-related osteonecrosis of the jaw.
Beth-Tasdogan NH, Mayer B, Hussein H, Zolk O
Cochrane Database Syst Rev 2017 Oct 6;10(10):CD012432. doi: 10.1002/14651858.CD012432.pub2. PMID: 28983908Free PMC Article

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