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Mediastinum neurofibroma

MedGen UID:
277354
•Concept ID:
C1334674
•
Neoplastic Process
Synonyms: Mediastinal Neurofibroma; mediastinal neurofibroma; mediastinum neurofibroma; Neurofibroma of Mediastinum; neurofibroma of mediastinum; Neurofibroma of the Mediastinum; neurofibroma of the mediastinum
 
Monarch Initiative: MONDO:0001426

Definition

A neurofibroma that arises from the posterior mediastinum. Excision is usually curative. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMediastinum neurofibroma

Professional guidelines

PubMed

Primary Mediastinal B-Cell Lymphoma: A 2021 Update on Genetics, Diagnosis, and Novel Therapeutics.
Ahmed Z, Afridi SS, Shahid Z, Zamani Z, Rehman S, Aiman W, Khan M, Mir MA, Awan FT, Anwer F, Iftikhar R
Clin Lymphoma Myeloma Leuk 2021 Nov;21(11):e865-e875. Epub 2021 Jun 24 doi: 10.1016/j.clml.2021.06.012. PMID: 34330673
Lymphomas of the Mediastinum and Their Differential Diagnosis.
Zhang ML, Sohani AR
Semin Diagn Pathol 2020 Jul;37(4):156-165. Epub 2020 May 15 doi: 10.1053/j.semdp.2020.04.005. PMID: 32451144
Surgical management of lung metastases.
Patrini D, Panagiotopoulos N, Lawrence D, Scarci M
Br J Hosp Med (Lond) 2017 Apr 2;78(4):192-198. doi: 10.12968/hmed.2017.78.4.192. PMID: 28398890

Recent clinical studies

Etiology

Pediatric mediastinal masses.
Sreedher G, Tadros SS, Janitz E
Pediatr Radiol 2022 Sep;52(10):1935-1947. Epub 2022 Jun 8 doi: 10.1007/s00247-022-05409-4. PMID: 35674800
Mediastinal neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: Pathology review and diagnostic approach.
Choi JH, Ro JY
Semin Diagn Pathol 2022 Mar;39(2):120-130. Epub 2021 Jun 15 doi: 10.1053/j.semdp.2021.06.007. PMID: 34167847
CT-based mediastinal compartment classifications and differential diagnosis of mediastinal tumors.
Nakazono T, Yamaguchi K, Egashira R, Takase Y, Nojiri J, Mizuguchi M, Irie H
Jpn J Radiol 2019 Feb;37(2):117-134. Epub 2018 Sep 20 doi: 10.1007/s11604-018-0777-5. PMID: 30238278
ITMIG Classification of Mediastinal Compartments and Multidisciplinary Approach to Mediastinal Masses.
Carter BW, Benveniste MF, Madan R, Godoy MC, de Groot PM, Truong MT, Rosado-de-Christenson ML, Marom EM
Radiographics 2017 Mar-Apr;37(2):413-436. Epub 2017 Jan 27 doi: 10.1148/rg.2017160095. PMID: 28129068
Intracardiac bronchogenic cyst.
Vaideeswar P, Agnihotri MA, Patwardhan AM
J Card Surg 2011 May;26(3):266-8. Epub 2011 Mar 28 doi: 10.1111/j.1540-8191.2011.01206.x. PMID: 21443547

Diagnosis

Pediatric mediastinal masses.
Sreedher G, Tadros SS, Janitz E
Pediatr Radiol 2022 Sep;52(10):1935-1947. Epub 2022 Jun 8 doi: 10.1007/s00247-022-05409-4. PMID: 35674800
Mediastinal neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: Pathology review and diagnostic approach.
Choi JH, Ro JY
Semin Diagn Pathol 2022 Mar;39(2):120-130. Epub 2021 Jun 15 doi: 10.1053/j.semdp.2021.06.007. PMID: 34167847
Approaching the patient with an anterior mediastinal mass: a guide for clinicians.
Carter BW, Marom EM, Detterbeck FC
J Thorac Oncol 2014 Sep;9(9 Suppl 2):S102-9. doi: 10.1097/JTO.0000000000000294. PMID: 25396306
Endobronchial ultrasound.
Burgers JA, Herth F, Becker HD
Lung Cancer 2001 Dec;34 Suppl 2:S109-13. doi: 10.1016/s0169-5002(01)00349-x. PMID: 11720750
Lung cancer.
Rodescu D
Med Clin North Am 1977 Nov;61(6):1205-18. doi: 10.1016/s0025-7125(16)31256-1. PMID: 72894

Therapy

Mediastinal Staging in Non-Small-Cell Lung Cancer: Saying Goodbye to Mediastinoscopy.
Dunne EG, Fick CN, Jones DR
J Clin Oncol 2023 Aug 1;41(22):3785-3790. Epub 2023 Jun 2 doi: 10.1200/JCO.23.00867. PMID: 37267507Free PMC Article
Primary mediastinal large B-cell lymphoma.
Savage KJ
Blood 2022 Sep 1;140(9):955-970. doi: 10.1182/blood.2020008376. PMID: 34496020
Mediastinal staging: when and how?
D'Andrilli A, Maurizi G, Venuta F, Rendina EA
Gen Thorac Cardiovasc Surg 2020 Jul;68(7):725-732. Epub 2019 Dec 3 doi: 10.1007/s11748-019-01263-8. PMID: 31797211
Segmentectomy for c-T1N0M0 non-small cell lung cancer.
Nomori H
Surg Today 2014 May;44(5):812-9. Epub 2013 Jun 29 doi: 10.1007/s00595-013-0649-7. PMID: 23812915
Lymphoblastic lymphoma.
Thomas DA, Kantarjian HM
Hematol Oncol Clin North Am 2001 Feb;15(1):51-95, vi. doi: 10.1016/s0889-8588(05)70200-8. PMID: 11253609

Prognosis

Mediastinal staging: when and how?
D'Andrilli A, Maurizi G, Venuta F, Rendina EA
Gen Thorac Cardiovasc Surg 2020 Jul;68(7):725-732. Epub 2019 Dec 3 doi: 10.1007/s11748-019-01263-8. PMID: 31797211
Mediastinal Epithelioid Hemangioendothelioma.
Kumar A, Lopez YK, Arrossi AV, Rubin B, Ashton R
Am J Respir Crit Care Med 2016 Feb 15;193(4):e7-8. doi: 10.1164/rccm.201510-1926IM. PMID: 26649628
Intracardiac bronchogenic cyst.
Vaideeswar P, Agnihotri MA, Patwardhan AM
J Card Surg 2011 May;26(3):266-8. Epub 2011 Mar 28 doi: 10.1111/j.1540-8191.2011.01206.x. PMID: 21443547
Restaging of the mediastinum.
Herth FJ, Ernst A, Eberhardt R
Curr Opin Pulm Med 2009 Jul;15(4):308-12. doi: 10.1097/MCP.0b013e32832cbee6. PMID: 19436205
Primary mediastinal tumours.
al-Naaman YD, al-Ani MS, al-Omeri MM
Thorax 1974 Jul;29(4):475-81. doi: 10.1136/thx.29.4.475. PMID: 4604946Free PMC Article

Clinical prediction guides

Pan-mediastinal neoplasm diagnosis via nationwide federated learning: a multicentre cohort study.
Tang R, Liang H, Guo Y, Li Z, Liu Z, Lin X, Yan Z, Liu J, Xu X, Shao W, Li S, Liang W, Wang W, Cui F, He H, Yang C, Jiang L, Wang H, Chen H, Guo C, Zhang H, Gao Z, He Y, Chen X, Zhao L, Yu H, Hu J, Zhao J, Li B, Yin C, Mao W, Lin W, Xie Y, Liu J, Li X, Wu D, Hou Q, Chen Y, Chen D, Xue Y, Liang Y, Tang W, Wang Q, Li E, Liu H, Wang G, Yu P, Chen C, Zheng B, Chen H, Zhang Z, Wang L, Wang A, Li Z, Fu J, Zhang G, Zhang J, Liu B, Zhao J, Deng B, Han Y, Leng X, Li Z, Zhang M, Liu C, Wang T, Luo Z, Yang C, Guo X, Ma K, Wang L, Jiang W, Han X, Wang Q, Qiao K, Xia Z, Zheng S, Xu C, Peng J, Wu S, Zhang Z, Huang H, Pang D, Liu Q, Li J, Ding X, Liu X, Zhong L, Lu Y, Xu F, Dai Q, He J
Lancet Digit Health 2023 Sep;5(9):e560-e570. doi: 10.1016/S2589-7500(23)00106-1. PMID: 37625894
Atherosclerotic Progression Is Related to Immune-Related Adverse Events.
Kurozumi A, Sakamoto K, Nakagawa T, Matsunaga F, Shimomura A, Shimizu C, Hara H, Hiroi Y
Int Heart J 2022;63(2):293-298. doi: 10.1536/ihj.21-657. PMID: 35354749
Confirmatory Mediastinoscopy after Negative Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for Mediastinal Staging of Lung Cancer: Systematic Review and Meta-analysis.
Sanz-Santos J, Almagro P, Malik K, Martinez-Camblor P, Caro C, Rami-Porta R
Ann Am Thorac Soc 2022 Sep;19(9):1581-1590. doi: 10.1513/AnnalsATS.202111-1302OC. PMID: 35348446
Transbronchial mediastinal cryobiopsy in the diagnosis of mediastinal lesions: a randomised trial.
Zhang J, Guo JR, Huang ZS, Fu WL, Wu XL, Wu N, Kuebler WM, Herth FJF, Fan Y
Eur Respir J 2021 Dec;58(6) Epub 2021 Dec 9 doi: 10.1183/13993003.00055-2021. PMID: 33958432
From the archives of the AFIP: tumors and tumorlike lesions of the testis: radiologic-pathologic correlation.
Woodward PJ, Sohaey R, O'Donoghue MJ, Green DE
Radiographics 2002 Jan-Feb;22(1):189-216. doi: 10.1148/radiographics.22.1.g02ja14189. PMID: 11796908

Recent systematic reviews

Is the diagnostic yield of mediastinal lymph node cryobiopsy (cryoEBUS) better for diagnosing mediastinal node involvement compared to endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)? A systematic review.
Botana-Rial M, Lojo-Rodríguez I, Leiro-Fernández V, Ramos-Hernández C, González-Montaos A, Pazos-Area L, Núñez-Delgado M, Fernández-Villar A
Respir Med 2023 Nov;218:107389. Epub 2023 Aug 12 doi: 10.1016/j.rmed.2023.107389. PMID: 37579981
Effect of Needle Size on Diagnosis of Sarcoidosis with Endobronchial Ultrasound-guided Transbronchial Needle Aspiration: Systematic Review and Meta-Analysis.
Kassirian S, Hinton SN, Iansavitchene A, Amjadi K, Chee A, Dhaliwal I, Mitchell MA
Ann Am Thorac Soc 2022 Feb;19(2):279-290. doi: 10.1513/AnnalsATS.202103-366OC. PMID: 35103562
Thoracotomy is better than thoracoscopic lobectomy in the lymph node dissection of lung cancer: a systematic review and meta-analysis.
Zhang W, Wei Y, Jiang H, Xu J, Yu D
World J Surg Oncol 2016 Nov 17;14(1):290. doi: 10.1186/s12957-016-1038-7. PMID: 27855709Free PMC Article
Robot-assisted minimally invasive esophagectomy for esophageal cancer: A systematic review.
Ruurda JP, van der Sluis PC, van der Horst S, van Hilllegersberg R
J Surg Oncol 2015 Sep;112(3):257-65. doi: 10.1002/jso.23922. PMID: 26390285
Thymoma and radiation therapy: a systematic review of medical treatment.
Giannopoulou A, Gkiozos I, Harrington KJ, Syrigos KN
Expert Rev Anticancer Ther 2013 Jun;13(6):759-66. doi: 10.1586/era.13.54. PMID: 23773107

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