U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Parotid Gland Monomorphic Adenoma

MedGen UID:
277505
•Concept ID:
C1335362
•
Neoplastic Process
Synonym: Parotid monomorphic adenoma

Definition

A benign epithelial neoplasm that arises from the parotid gland. It is characterized by the presence of a monomorphic cellular infiltrate. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParotid Gland Monomorphic Adenoma

Professional guidelines

PubMed

Pediatric primary salivary gland tumors.
Jesberg P, Monzon A, Gitomer SA, Herrmann BW
Am J Otolaryngol 2023 Sep-Oct;44(5):103948. Epub 2023 Jun 8 doi: 10.1016/j.amjoto.2023.103948. PMID: 37352681
Etiology and management of recurrent parotid pleomorphic adenoma.
Witt RL, Eisele DW, Morton RP, Nicolai P, Poorten VV, Zbären P
Laryngoscope 2015 Apr;125(4):888-93. Epub 2014 Oct 7 doi: 10.1002/lary.24964. PMID: 25289881
Combined surgical-radiological treatment of parotid gland fistulae.
Schindel J, Markowicz H, Levie B
J Laryngol Otol 1968 Oct;82(10):867-70. doi: 10.1017/s0022215100069607. PMID: 4301049

Recent clinical studies

Etiology

Risk factors for subsequent recurrence after surgical treatment of recurrent pleomorphic adenoma of the parotid gland.
Rooker SA, Van Abel KM, Yin LX, Nagelschneider AA, Price DL, Olsen KD, Janus JR, Kasperbauer JL, Moore EJ
Head Neck 2021 Apr;43(4):1088-1096. Epub 2020 Dec 4 doi: 10.1002/hed.26570. PMID: 33275822
Outcomes of drainless outpatient parotidectomy.
Coniglio AJ, Deal AM, Hackman TG
Head Neck 2019 Jul;41(7):2154-2158. Epub 2019 Feb 1 doi: 10.1002/hed.25671. PMID: 30706566
Benign Parotid Tumors.
Zhan KY, Khaja SF, Flack AB, Day TA
Otolaryngol Clin North Am 2016 Apr;49(2):327-42. doi: 10.1016/j.otc.2015.10.005. PMID: 27040584
Local capsular dissection of parotid pleomorphic adenomas.
Dallera P, Marchetti C, Campobassi A
Int J Oral Maxillofac Surg 1993 Jun;22(3):154-7. doi: 10.1016/s0901-5027(05)80241-3. PMID: 8393467
Parathyroid adenomas following irradiation.
Russ JE, Scanlon EF, Sener SF
Cancer 1979 Mar;43(3):1078-83. doi: 10.1002/1097-0142(197903)43:3<1078::aid-cncr2820430344>3.0.co;2-r. PMID: 154967

Diagnosis

Pathology Mimicking Orofacial Pain.
Sandhu S, Handa S
Dent Clin North Am 2023 Jan;67(1):117-127. Epub 2022 Oct 27 doi: 10.1016/j.cden.2022.07.009. PMID: 36404072
Sclerosing Polycystic Adenoma.
Bishop JA, Thompson LDR
Surg Pathol Clin 2021 Mar;14(1):17-24. doi: 10.1016/j.path.2020.09.004. PMID: 33526220
Pleomorphic Adenoma in the Parotid Gland.
Erickson LA
Mayo Clin Proc 2017 Mar;92(3):e55-e56. doi: 10.1016/j.mayocp.2017.01.006. PMID: 28259235
Benign Parotid Tumors.
Zhan KY, Khaja SF, Flack AB, Day TA
Otolaryngol Clin North Am 2016 Apr;49(2):327-42. doi: 10.1016/j.otc.2015.10.005. PMID: 27040584
Salivary glands.
Silvers AR, Som PM
Radiol Clin North Am 1998 Sep;36(5):941-66, vi. doi: 10.1016/s0033-8389(05)70070-1. PMID: 9747195

Therapy

Gustatory Hyperhidrosis after Parotid Surgery.
Huang TR, Lee JC
N Engl J Med 2024 Sep 12;391(10):e21. Epub 2024 Sep 7 doi: 10.1056/NEJMicm2404232. PMID: 39248341
Modified facelift incision for partial parotidectomy versus bayonet-shaped incision: a comparison using visual analog scale.
Bulut OC, Plinkert P, Federspil PA
Eur Arch Otorhinolaryngol 2016 Oct;273(10):3269-75. Epub 2016 Jan 9 doi: 10.1007/s00405-015-3878-0. PMID: 26749559
Gustatory itching: an unusual complication following superficial parotidectomy.
Ricks R, Banga R, Porter M
J Laryngol Otol 2010 Nov;124(11):1227-8. Epub 2010 May 20 doi: 10.1017/S0022215110001039. PMID: 20482949
Local capsular dissection of parotid pleomorphic adenomas.
Dallera P, Marchetti C, Campobassi A
Int J Oral Maxillofac Surg 1993 Jun;22(3):154-7. doi: 10.1016/s0901-5027(05)80241-3. PMID: 8393467
Parathyroid adenomas following irradiation.
Russ JE, Scanlon EF, Sener SF
Cancer 1979 Mar;43(3):1078-83. doi: 10.1002/1097-0142(197903)43:3<1078::aid-cncr2820430344>3.0.co;2-r. PMID: 154967

Prognosis

Sclerosing Polycystic Adenoma.
Bishop JA, Thompson LDR
Surg Pathol Clin 2021 Mar;14(1):17-24. doi: 10.1016/j.path.2020.09.004. PMID: 33526220
Salivary duct carcinoma of the parotid gland: case report and review of the literature.
Jamal AM, Sun ZJ, Chen XM, Zhao YF
J Oral Maxillofac Surg 2008 Aug;66(8):1708-13. doi: 10.1016/j.joms.2007.05.024. PMID: 18634961
Local capsular dissection of parotid pleomorphic adenomas.
Dallera P, Marchetti C, Campobassi A
Int J Oral Maxillofac Surg 1993 Jun;22(3):154-7. doi: 10.1016/s0901-5027(05)80241-3. PMID: 8393467
Mucoepidermoid carcinoma of the parotid gland.
Jakobsson PA, Blanck C, Eneroth CM
Cancer 1968 Jul;22(1):111-24. doi: 10.1002/1097-0142(196807)22:1<111::aid-cncr2820220114>3.0.co;2-j. PMID: 4298176
PARAPHARYNGEAL TUMORS.
FLUUR E
Arch Otolaryngol 1964 Nov;80:557-65. doi: 10.1001/archotol.1964.00750040571010. PMID: 14216016

Clinical prediction guides

Risk of Carcinoma in Pleomorphic Adenomas of the Parotid.
Levyn H, Subramanian T, Eagan A, Katabi N, Lin O, Badillo ND, Martinez G, Scholfield DW, Wong RJ, Shah JP, Givi B, Morris LGT, Ganly I, Patel SG
JAMA Otolaryngol Head Neck Surg 2023 Nov 1;149(11):1034-1041. doi: 10.1001/jamaoto.2023.3212. PMID: 37824134Free PMC Article
Pediatric primary salivary gland tumors.
Jesberg P, Monzon A, Gitomer SA, Herrmann BW
Am J Otolaryngol 2023 Sep-Oct;44(5):103948. Epub 2023 Jun 8 doi: 10.1016/j.amjoto.2023.103948. PMID: 37352681
Surgical treatment of pleomorphic adenoma of parotid gland in children: a systematic review.
Galluzzi F, Garavello W
Auris Nasus Larynx 2022 Aug;49(4):547-553. Epub 2022 Jan 31 doi: 10.1016/j.anl.2022.01.013. PMID: 35101285
Intraparotid schwannoma.
McCarthy WA, Cox BL
Arch Pathol Lab Med 2014 Jul;138(7):982-5. doi: 10.5858/arpa.2013-0014-RS. PMID: 24978928
Malignant oncocytoma.
Laurian N, Zohar Y, Kende L
J Laryngol Otol 1977 Sep;91(9):805-8. doi: 10.1017/s0022215100084383. PMID: 915379

Recent systematic reviews

Salivary Gland Oncocytomas. A Systematic Review.
Alberto PL, Ashim S, Megan K, Wei Z, Nestor G, Matthew Z, Dayana M, Marcelo V, John W
Head Neck Pathol 2024 Nov 30;18(1):126. doi: 10.1007/s12105-024-01730-6. PMID: 39614964Free PMC Article
Clinicopathological profile of sclerosing polycystic adenoma/adenosis: A systematic review.
de Carvalho Kimura T, de Lima-Souza RA, Scarini JF, Lavareze L, Egal ESA, Altemani A, Mariano FV
Head Neck 2023 Sep;45(9):2449-2457. Epub 2023 Jul 5 doi: 10.1002/hed.27435. PMID: 37403748
Surgical treatment of pleomorphic adenoma of parotid gland in children: a systematic review.
Galluzzi F, Garavello W
Auris Nasus Larynx 2022 Aug;49(4):547-553. Epub 2022 Jan 31 doi: 10.1016/j.anl.2022.01.013. PMID: 35101285
Elective neck dissection in salivary gland malignancies: Systematic review and meta-analysis.
Yan F, Lao WP, Nguyen SA, Sharma AK, Day TA
Head Neck 2022 Feb;44(2):505-517. Epub 2021 Dec 4 doi: 10.1002/hed.26923. PMID: 34862810
Parotid incidentalomas: a systematic review.
Thompson C, Nolli T, Bannister M
J Laryngol Otol 2021 Sep;135(9):765-769. Epub 2021 Jul 26 doi: 10.1017/S0022215121002036. PMID: 34308809

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...