Four-vessel umbilical cord

MedGen UID:: 287067
•Concept ID:: C1562363
•: Congenital Abnormality

Synonym:	Four vessel umbilical cord
SNOMED CT:	Four vessels in umbilical cord (417426005)

HPO:	HP:0032513

Definition

Four-vessel umbilical cord containing two arteries and two veins. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVFour-vessel umbilical cord

Phenotypic abnormality
- Abnormality of prenatal development or birth
  - Abnormalities of placenta or umbilical cord
    - Abnormality of the umbilical cord
      - Abnormal umbilical cord blood vessel morphology
        Four-vessel umbilical cord

Recent clinical studies

Etiology

Supernumerary umbilical vein in a hydropic neonate with hypertrophic cardiomyopathy.

Karatza A, Tsamandas A, Varvarigou A, Davlouros P, Pavlou V, Mantagos S
Fetal Pediatr Pathol 2011;30(3):173-6. Epub 2011 Feb 28 doi: 10.3109/15513815.2010.547557. PMID: 21355676

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Diagnosis

A partial supernumerary umbilical vein: a case report.

Kurakazu M, Kurakazu M, Murata M, Miyamoto T, Takahashi Y, Hamasaki M, Ohta E, Yotsumoto F, Miyamoto S
J Med Case Rep 2019 May 18;13(1):149. doi: 10.1186/s13256-019-2094-8. PMID: 31101065 Free PMC Article

Prenatal diagnosis of four-vessel umbilical cord with supernumerary vein varix: A case report and literature review.

Lei T, Xie HN, Feng JL
J Obstet Gynaecol Res 2017 Jul;43(7):1200-1204. Epub 2017 May 31 doi: 10.1111/jog.13324. PMID: 28561938

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