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Neurocytoma

MedGen UID:
302013
•Concept ID:
C1622510
•
Neoplastic Process
Synonym: Neurocytomas
SNOMED CT: Neurocytoma (128858006)
 
HPO: HP:0030064

Definition

A benign brain tumor composed of neural elements which most often arise from the septum pellucidum and the walls of the lateral ventricles. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeurocytoma

Professional guidelines

PubMed

Primary intraventricular tumors - Imaging characteristics, post-treatment changes and relapses.
Chong AW, McAdory LE, Low DCY, Lim EJ, Leong NWL, Ho CL
Clin Imaging 2022 Feb;82:38-52. Epub 2021 Oct 29 doi: 10.1016/j.clinimag.2021.10.008. PMID: 34773811
The role of chemotherapy in the treatment of central neurocytoma.
Johnson MO, Kirkpatrick JP, Patel MP, Desjardins A, Randazzo DM, Friedman HS, Ashley DM, Peters KB
CNS Oncol 2019 Nov 1;8(3):CNS41. Epub 2019 Nov 5 doi: 10.2217/cns-2019-0012. PMID: 31686534Free PMC Article
The management of residual or recurrent central neurocytoma.
Thawani JP, Lee JY
Neurosurg Clin N Am 2015 Jan;26(1):67-81. doi: 10.1016/j.nec.2014.09.002. PMID: 25432185

Recent clinical studies

Etiology

Overview of the 2022 WHO Classification of Pituitary Tumors.
Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Extraventricular neurocytomas: a systematic review of the literature in the pediatric population.
Lampros MG, Vlachos N, Voulgaris S, Alexiou GA
Childs Nerv Syst 2021 Aug;37(8):2465-2474. Epub 2021 Jun 17 doi: 10.1007/s00381-021-05257-x. PMID: 34137942
FGFR- gene family alterations in low-grade neuroepithelial tumors.
Bale TA
Acta Neuropathol Commun 2020 Feb 21;8(1):21. doi: 10.1186/s40478-020-00898-6. PMID: 32085805Free PMC Article
Upfront Gamma Knife Surgery for Giant Central Neurocytoma.
Chen KP, Lee CC, Liao CL, Yang TC, Chiu TL, Su CF
World Neurosurg 2017 Jan;97:751.e15-751.e21. Epub 2016 Oct 21 doi: 10.1016/j.wneu.2016.10.073. PMID: 27777164
Pediatric Central Neurocytoma.
Karthigeyan M, Gupta K, Salunke P
J Child Neurol 2017 Jan;32(1):53-59. Epub 2016 Sep 29 doi: 10.1177/0883073816668994. PMID: 27664193

Diagnosis

Overview of the 2022 WHO Classification of Pituitary Tumors.
Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
MRI of intracranial intraventricular lesions.
Muly S, Liu S, Lee R, Nicolaou S, Rojas R, Khosa F
Clin Imaging 2018 Nov-Dec;52:226-239. Epub 2018 Aug 1 doi: 10.1016/j.clinimag.2018.07.021. PMID: 30138862
Extraventricular neurocytomas.
Sweiss FB, Lee M, Sherman JH
Neurosurg Clin N Am 2015 Jan;26(1):99-104. doi: 10.1016/j.nec.2014.09.004. PMID: 25432188
Cerebellar liponeurocytoma.
Nishimoto T, Kaya B
Arch Pathol Lab Med 2012 Aug;136(8):965-9. doi: 10.5858/arpa.2011-0337-RS. PMID: 22849747
Intraventricular neurocytoma.
Ng P, Soo YS, Chaseling R, O'Neil P
Australas Radiol 1996 May;40(2):125-33. doi: 10.1111/j.1440-1673.1996.tb00365.x. PMID: 8687343

Therapy

Simplified anterior transpetrosal approach without superior petrosal sinus and tentorial incision for lesions centered in Meckel's cave.
Shibao S, Yoshida K
Acta Neurochir (Wien) 2023 Jul;165(7):1833-1839. Epub 2023 Apr 26 doi: 10.1007/s00701-023-05584-9. PMID: 37099067
Large lateral intraventricular tumors - Outcome of radical surgery.
Goel A, Vutha R, Shah A, Singh K, Goel N, Shenoy A, Rai S, Dandpat S
J Clin Neurosci 2021 Jun;88:205-212. Epub 2021 Apr 14 doi: 10.1016/j.jocn.2021.03.040. PMID: 33992185
The role of chemotherapy in the treatment of central neurocytoma.
Johnson MO, Kirkpatrick JP, Patel MP, Desjardins A, Randazzo DM, Friedman HS, Ashley DM, Peters KB
CNS Oncol 2019 Nov 1;8(3):CNS41. Epub 2019 Nov 5 doi: 10.2217/cns-2019-0012. PMID: 31686534Free PMC Article
Central neurocytoma responsive to topotecan, ifosfamide, carboplatin.
Amini E, Roffidal T, Lee A, Fuller GN, Mahajan A, Ketonen L, Kobrinsky N, Cairo MS, Wells RJ, Wolff JE
Pediatr Blood Cancer 2008 Jul;51(1):137-40. doi: 10.1002/pbc.21551. PMID: 18338396
Chemotherapy of brain tumors.
Galanis E, Buckner JC
Curr Opin Neurol 2000 Dec;13(6):619-25. doi: 10.1097/00019052-200012000-00002. PMID: 11148660

Prognosis

Pediatric Central Neurocytoma.
Karthigeyan M, Gupta K, Salunke P
J Child Neurol 2017 Jan;32(1):53-59. Epub 2016 Sep 29 doi: 10.1177/0883073816668994. PMID: 27664193
Rare pediatric central neurocytomas.
Phi JH, Kim DG
Neurosurg Clin N Am 2015 Jan;26(1):105-8. doi: 10.1016/j.nec.2014.09.015. PMID: 25432189
Cerebellar liponeurocytoma.
Nishimoto T, Kaya B
Arch Pathol Lab Med 2012 Aug;136(8):965-9. doi: 10.5858/arpa.2011-0337-RS. PMID: 22849747
Cerebellar liponeurocytoma.
Owler BK, Makeham JM, Shingde M, Besser M
J Clin Neurosci 2005 Apr;12(3):326-9. doi: 10.1016/j.jocn.2004.05.017. PMID: 15851097
Intraventricular neurocytoma.
Ng P, Soo YS, Chaseling R, O'Neil P
Australas Radiol 1996 May;40(2):125-33. doi: 10.1111/j.1440-1673.1996.tb00365.x. PMID: 8687343

Clinical prediction guides

Upfront Gamma Knife Surgery for Giant Central Neurocytoma.
Chen KP, Lee CC, Liao CL, Yang TC, Chiu TL, Su CF
World Neurosurg 2017 Jan;97:751.e15-751.e21. Epub 2016 Oct 21 doi: 10.1016/j.wneu.2016.10.073. PMID: 27777164
Pediatric Central Neurocytoma.
Karthigeyan M, Gupta K, Salunke P
J Child Neurol 2017 Jan;32(1):53-59. Epub 2016 Sep 29 doi: 10.1177/0883073816668994. PMID: 27664193
Neurocytoma of the spinal cord: report of three cases and review of the literature.
Polli FM, Salvati M, Miscusi M, Delfini R, Giangaspero F
Acta Neurochir (Wien) 2009 Jun;151(6):569-74; discussion 574. Epub 2009 Apr 23 doi: 10.1007/s00701-009-0305-6. PMID: 19387541
Papillary glioneuronal tumor.
Prayson RA
Arch Pathol Lab Med 2000 Dec;124(12):1820-3. doi: 10.5858/2000-124-1820-PGT. PMID: 11100065
Atypical central neurocytoma.
Söylemezoglu F, Scheithauer BW, Esteve J, Kleihues P
J Neuropathol Exp Neurol 1997 May;56(5):551-6. doi: 10.1097/00005072-199705000-00011. PMID: 9143268

Recent systematic reviews

Gamma Knife radiosurgery for central neurocytoma: a quantitative systematic review and metanalysis.
Spina A, Garbin E, Albano L, Bisoglio A, Boari N, Mortini P
Neurosurg Rev 2024 Jan 24;47(1):64. doi: 10.1007/s10143-024-02301-7. PMID: 38265530
Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification.
Gagliardi F, De Domenico P, Garbin E, Snider S, Mortini P
J Pineal Res 2023 Dec;75(4):e12910. Epub 2023 Sep 13 doi: 10.1111/jpi.12910. PMID: 37705383
Lateral ventricular liponeurocytoma: Review of literature and case illustration.
Al-Umran MR, Al-Umran SR, Arab AF, Dababo MA, Alotaibi FA
Neurochirurgie 2021 Nov;67(6):579-586. Epub 2021 Mar 22 doi: 10.1016/j.neuchi.2021.03.004. PMID: 33766564
Imaging of extraventricular neurocytoma: a systematic literature review.
Romano N, Federici M, Castaldi A
Radiol Med 2020 Oct;125(10):961-970. Epub 2020 Apr 25 doi: 10.1007/s11547-020-01198-8. PMID: 32335813
Stereotactic radiosurgery for central neurocytoma: a quantitative systematic review.
Park HK, Steven D C
J Neurooncol 2012 May;108(1):115-21. doi: 10.1007/s11060-012-0803-x. PMID: 22442020

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