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Tubular variant testicular seminoma

MedGen UID:
308259
•Concept ID:
C1515294
•
Neoplastic Process
Synonyms: Testicular Seminoma, Tubular Variant; testicular seminoma, tubular variant; tubular variant testicular seminoma
 
Monarch Initiative: MONDO:0003973

Definition

A morphologic variant of testicular seminoma characterized by the presence of seminoma cells arranged in tubular patterns and few lymphocytes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTubular variant testicular seminoma

Professional guidelines

PubMed

Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues.
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467

Recent clinical studies

Etiology

Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues.
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467
Germ cell neoplasms of the testis.
Ulbright TM
Am J Surg Pathol 1993 Nov;17(11):1075-91. doi: 10.1097/00000478-199311000-00001. PMID: 8214253

Diagnosis

Pitfalls in the interpretation of specimens from patients with testicular tumours, with an emphasis on variant morphologies.
Ulbright TM
Pathology 2018 Jan;50(1):88-99. Epub 2017 Nov 10 doi: 10.1016/j.pathol.2017.07.013. PMID: 29129333
Seminoma with tubular, microcystic, and related patterns: a study of 28 cases of unusual morphologic variants that often cause confusion with yolk sac tumor.
Ulbright TM, Young RH
Am J Surg Pathol 2005 Apr;29(4):500-5. doi: 10.1097/01.pas.0000155146.60670.3f. PMID: 15767805
Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues.
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467
Tubular seminoma. An immunohistochemical and DNA flow-cytometric study of four cases.
Zavala-Pompa A, Ro JY, el-Naggar AK, Amin MB, Ordóñez NG, Sella A, Ayala AG
Am J Clin Pathol 1994 Oct;102(4):397-401. doi: 10.1093/ajcp/102.4.397. PMID: 7524297

Therapy

Seminoma with tubular, microcystic, and related patterns: a study of 28 cases of unusual morphologic variants that often cause confusion with yolk sac tumor.
Ulbright TM, Young RH
Am J Surg Pathol 2005 Apr;29(4):500-5. doi: 10.1097/01.pas.0000155146.60670.3f. PMID: 15767805

Prognosis

Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues.
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467

Clinical prediction guides

Seminoma with tubular, microcystic, and related patterns: a study of 28 cases of unusual morphologic variants that often cause confusion with yolk sac tumor.
Ulbright TM, Young RH
Am J Surg Pathol 2005 Apr;29(4):500-5. doi: 10.1097/01.pas.0000155146.60670.3f. PMID: 15767805

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