Warning: The NCBI web site requires JavaScript to function. more...

Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

Ovarian sertoli-stromal cell tumor

MedGen UID:: 309515
•Concept ID:: C1518732
•: Neoplastic Process

Synonyms:	Ovarian Sertoli-Stromal Cell Tumor; ovarian sertoli-stromal cell tumor; Ovarian Sertoli-Stromal Cell Tumour; Ovarian Sertoli-Stromal Tumor; Ovarian Sertoli-Stromal Tumour

Monarch Initiative:	MONDO:0020807

Definition

A sex cord-stromal tumor that arises from the ovary and is composed entirely of, or in various combinations of, Sertoli cells, Leydig cells, and fibroblast-like cells. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVOvarian sertoli-stromal cell tumor

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Neoplasm
      - Ovarian sex cord-stromal tumor
        Ovarian sertoli-stromal cell tumor
        Ovarian Sertoli Cell Tumor
        Ovarian Sertoli Cell Tumor with Lipid Storage
        Ovarian Sertoli-Leydig cell tumor
        Moderately Differentiated Ovarian Sertoli-Leydig Cell Tumor
        Moderately Differentiated Ovarian Sertoli-Leydig Cell Tumor, Variant with Heterologous Elements
        Ovarian Retiform Sertoli-Leydig Cell Tumor
        Ovarian Retiform Sertoli-Leydig Cell Tumor, Variant with Heterologous Elements
        Ovarian Sertoli-Leydig Cell Tumor with Heterologous Elements
        Poorly Differentiated Ovarian Sertoli-Leydig Cell Tumor, Variant with Heterologous Elements
        Ovarian Sertoli-Leydig Cell Tumor with Retiform Elements
        Poorly Differentiated Ovarian Sertoli-Leydig Cell Tumor
        Well Differentiated Ovarian Sertoli-Leydig Cell Tumor
        Ovarian Stromal-Leydig Cell Tumor

Recent clinical studies

Etiology

Expression of a transcription factor, SOX9, in Sertoli-stromal cell tumors of the ovary.

Kato N, Fukase M, Motoyama T
Int J Gynecol Pathol 2004 Apr;23(2):180-1. doi: 10.1097/00004347-200404000-00014. PMID: 15084848

Diagnosis

Utility of immunohistochemistry in distinguishing ovarian sertoli-stromal cell tumors from carcinosarcomas.

Costa MJ, Morris RJ, Wilson R, Judd R
Hum Pathol 1992 Jul;23(7):787-97. doi: 10.1016/0046-8177(92)90349-8. PMID: 1612579

Supplemental Content

Table of contents

Clinical resources

ClinicalTrials.gov

Practice guidelines

Bookshelf
See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

Consumer resources

MedlinePlus

Reviews

Related information

PubMed
Related literature resources in PubMed

Recent activity

Clear Turn Off Turn On

Ovarian sertoli-stromal cell tumor
Ovarian sertoli-stromal cell tumor

MedGen

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...