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Cusp Tear

MedGen UID:
310643
•Concept ID:
C1707539
•
Disease or Syndrome

Definition

A split located on a leaflet of a heart valve that prevents its complete closing, which can result in valvular dysfunction. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCusp Tear

Recent clinical studies

Etiology

Impact of postoperative patient-prosthesis mismatch as a risk factor for early structural valve deterioration after aortic valve replacement with Trifecta bioprosthesis.
Wakami T, Koizumi S, Koyama T
J Cardiothorac Surg 2022 Jul 8;17(1):174. doi: 10.1186/s13019-022-01918-3. PMID: 35804395Free PMC Article
Early First-Generation Trifecta Valve Failure: A Case Series and a Review of the Literature.
Kaneyuki D, Nakajima H, Asakura T, Yoshitake A, Tokunaga C, Tochii M, Hayashi J, Takazawa A, Izumida H, Iguchi A
Ann Thorac Surg 2020 Jan;109(1):86-92. Epub 2019 Jul 20 doi: 10.1016/j.athoracsur.2019.05.073. PMID: 31336064
Stentless aortic valve replacement: an update.
Kobayashi J
Vasc Health Risk Manag 2011;7:345-51. Epub 2011 Jun 2 doi: 10.2147/VHRM.S11253. PMID: 21731886Free PMC Article
A lesional classification to standardize surgical management of aortic insufficiency towards valve repair.
Lansac E, Di Centa I, Raoux F, Al Attar N, Acar C, Joudinaud T, Raffoul R
Eur J Cardiothorac Surg 2008 May;33(5):872-8; discussion 878-80. Epub 2008 Feb 6 doi: 10.1016/j.ejcts.2007.12.033. PMID: 18258445
Ionescu-Shiley valve failure. I: Experience with 125 standard-profile explants.
Walley VM, Keon CA, Khalili M, Moher D, Campagna M, Keon WJ
Ann Thorac Surg 1992 Jul;54(1):111-6. doi: 10.1016/0003-4975(92)91153-z. PMID: 1610221

Diagnosis

Leaflet tear in a Trifecta aortic bioprosthesis 34 months after implantation.
Piñón M, Durán D, Pazos P, Pradas G
Interact Cardiovasc Thorac Surg 2015 Feb;20(2):281-2. Epub 2014 Nov 16 doi: 10.1093/icvts/ivu384. PMID: 25404230
Traumatic sinus of Valsalva fistula and aortic valve rupture.
Murray EG, Minami K, Körtke H, Seggewiss H, Körfer R
Ann Thorac Surg 1993 Mar;55(3):760-1. doi: 10.1016/0003-4975(93)90290-x. PMID: 8452445
Long-term echocardiographic follow-up of patients with a tricuspid bioprosthesis.
Okada Y, Nasu M, Nishiuchi S, Shomura T
ASAIO Trans 1990 Jul-Sep;36(3):M535-7. PMID: 2252744
Doppler and echocardiographic features of normal and dysfunctioning bioprosthetic valves.
Alam M, Rosman HS, Lakier JB, Kemp S, Khaja F, Hautamaki K, Magilligan DJ Jr, Stein PD
J Am Coll Cardiol 1987 Oct;10(4):851-8. doi: 10.1016/s0735-1097(87)80280-2. PMID: 3309005
Applications of pulsed Doppler flow mapping to left sided cardiac valvular lesions.
Kalmanson D, Veyrat C, Gourtchiglouian C, Bas S, Abitbol G
Int J Card Imaging 1986-1987;2(1):37-45. doi: 10.1007/BF01553935. PMID: 2959728

Therapy

Impact of postoperative patient-prosthesis mismatch as a risk factor for early structural valve deterioration after aortic valve replacement with Trifecta bioprosthesis.
Wakami T, Koizumi S, Koyama T
J Cardiothorac Surg 2022 Jul 8;17(1):174. doi: 10.1186/s13019-022-01918-3. PMID: 35804395Free PMC Article
Two cases of catastrophic deterioration and multiple leaflet detachment in Trifecta valves.
Imai N, Kaminishi Y, Tsukada T, Osaka M, Sakamoto H, Mathis BJ, Suzuki Y, Hiramatsu Y
Gen Thorac Cardiovasc Surg 2022 Mar;70(3):292-294. Epub 2022 Jan 17 doi: 10.1007/s11748-021-01749-4. PMID: 35038125
Early Degeneration Caused by Cusp Tear of First-Generation Trifecta Bioprosthesis.
Eichinger S, Badreldin AMA, Eichinger WB
Ann Thorac Surg 2018 Dec;106(6):e297-e298. Epub 2018 Apr 30 doi: 10.1016/j.athoracsur.2018.03.063. PMID: 29723533
Pure Cusp Tear of Trifecta Bioprosthesis 2 Years after Aortic Valve Replacement.
Hamamoto M, Kobayashi T, Ozawa M, Yoshimura K
Ann Thorac Cardiovasc Surg 2017 Jun 20;23(3):157-160. Epub 2016 Dec 14 doi: 10.5761/atcs.cr.16-00183. PMID: 27980283Free PMC Article
Stentless aortic valve replacement: an update.
Kobayashi J
Vasc Health Risk Manag 2011;7:345-51. Epub 2011 Jun 2 doi: 10.2147/VHRM.S11253. PMID: 21731886Free PMC Article

Prognosis

Aortic regurgitation due to perforation of the right coronary cusp 10 years after implantation of a freestyle stentless bioprosthesis.
Okamoto Y, Katsu M, Matsumoto M
J Card Surg 2011 Nov;26(6):613-4. Epub 2011 Sep 26 doi: 10.1111/j.1540-8191.2011.01303.x. PMID: 21951139
The CryoLife-O'Brien stentless replacement aortic valve: patterns of valve failure.
Chambers JB, Parkin D, Rajani R, Shabbo F
J Heart Valve Dis 2011 Jul;20(4):433-8. PMID: 21863657
Long-term results after aortic valve replacement with the Mitroflow pericardial valve.
Reber D, Birnbaum DE, Tollenaere P, Eschenbruch E
J Cardiovasc Surg (Torino) 1996 Dec;37(6 Suppl 1):23-7. PMID: 10064343
The Mitroflow pericardial valve. First five years of follow-up evaluation.
Loisance D, Zouari M, Leandri J, Hillion ML, Cachera JP
ASAIO Trans 1989 Jul-Sep;35(3):304-7. doi: 10.1097/00002480-198907000-00041. PMID: 2597470
Failure of Hancock xenograft valve: importance of valve position (4- to 9-year follow-up).
Bolooki H, Mallon S, Kaiser GA, Thurer RJ, Kieval J
Ann Thorac Surg 1983 Sep;36(3):246-52. doi: 10.1016/s0003-4975(10)60124-5. PMID: 6615061

Clinical prediction guides

Impact of postoperative patient-prosthesis mismatch as a risk factor for early structural valve deterioration after aortic valve replacement with Trifecta bioprosthesis.
Wakami T, Koizumi S, Koyama T
J Cardiothorac Surg 2022 Jul 8;17(1):174. doi: 10.1186/s13019-022-01918-3. PMID: 35804395Free PMC Article
Valve-sparing operation for balloon-induced aortic regurgitation in congenital aortic stenosis.
Bacha EA, Satou GM, Moran AM, Zurakowski D, Marx GR, Keane JF, Jonas RA
J Thorac Cardiovasc Surg 2001 Jul;122(1):162-8. doi: 10.1067/mtc.2001.114639. PMID: 11436050
Ionescu-Shiley valve failure. I: Experience with 125 standard-profile explants.
Walley VM, Keon CA, Khalili M, Moher D, Campagna M, Keon WJ
Ann Thorac Surg 1992 Jul;54(1):111-6. doi: 10.1016/0003-4975(92)91153-z. PMID: 1610221
Long-term echocardiographic follow-up of patients with a tricuspid bioprosthesis.
Okada Y, Nasu M, Nishiuchi S, Shomura T
ASAIO Trans 1990 Jul-Sep;36(3):M535-7. PMID: 2252744
The Mitroflow pericardial valve. First five years of follow-up evaluation.
Loisance D, Zouari M, Leandri J, Hillion ML, Cachera JP
ASAIO Trans 1989 Jul-Sep;35(3):304-7. doi: 10.1097/00002480-198907000-00041. PMID: 2597470

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