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Rectosigmoid Mucinous Adenocarcinoma

MedGen UID:
311207
•Concept ID:
C1709867
•
Neoplastic Process

Definition

An invasive adenocarcinoma of the rectosigmoid area characterized by the presence of pools of extracellular mucin. Malignant glandular epithelial cells are present in the mucin collections. Mucin constitutes more than 50% of the lesion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRectosigmoid Mucinous Adenocarcinoma

Professional guidelines

PubMed

Pseudomyxoma peritonei: natural history and treatment.
Mittal R, Chandramohan A, Moran B
Int J Hyperthermia 2017 Aug;33(5):511-519. doi: 10.1080/02656736.2017.1310938. PMID: 28540829
En-bloc pelvic resection with concomitant rectosigmoid colectomy and immediate anastomosis as part of primary cytoreductive surgery for patients with advanced ovarian cancer.
Yildirim Y, Ertas IE, Nayki U, Ulug P, Nayki C, Yilmaz I, Gultekin E, Dogan A, Aykas A, Ulug S, Ozdemir A, Solmaz U
Eur J Gynaecol Oncol 2014;35(4):400-7. PMID: 25118481

Recent clinical studies

Etiology

Clinical, endoscopic and histological profile of colorectal cancers seen on colonoscopy in Kano, North-Western Nigeria.
Musa Y, Mohammed MF, Muhammad NO, Yusuf I, Abdulrahim AO, Samaila AA, Borodo MM
Niger Postgrad Med J 2021 Jan-Mar;28(1):22-26. doi: 10.4103/npmj.npmj_288_20. PMID: 33642320
Mesenteric lymph node involvement in advanced ovarian cancer patients undergoing rectosigmoid resection: prognostic role and clinical considerations.
Gallotta V, Fanfani F, Fagotti A, Chiantera V, Legge F, Gueli Alletti S, Nero C, Margariti AP, Papa V, Alfieri S, Ciccarone F, Scambia G, Ferrandina G
Ann Surg Oncol 2014 Jul;21(7):2369-75. Epub 2014 Feb 21 doi: 10.1245/s10434-014-3558-0. PMID: 24558070
Colorectal carcinoma in children.
Karnak I, Ciftci AO, Senocak ME, Büyükpamukçu N
J Pediatr Surg 1999 Oct;34(10):1499-504. doi: 10.1016/s0022-3468(99)90112-4. PMID: 10549756
Peanut lectin-binding sites in large bowel carcinoma.
Cooper HS
Lab Invest 1982 Oct;47(4):383-90. PMID: 6289006
The significance of the signet-cell variety of adenocarcinoma of the rectum.
Bonello JC, Sternberg SS, Quan SH
Dis Colon Rectum 1980 Apr;23(3):180-3. doi: 10.1007/BF02587622. PMID: 6247125

Diagnosis

Clinical, endoscopic and histological profile of colorectal cancers seen on colonoscopy in Kano, North-Western Nigeria.
Musa Y, Mohammed MF, Muhammad NO, Yusuf I, Abdulrahim AO, Samaila AA, Borodo MM
Niger Postgrad Med J 2021 Jan-Mar;28(1):22-26. doi: 10.4103/npmj.npmj_288_20. PMID: 33642320
Pseudomyxoma peritonei: natural history and treatment.
Mittal R, Chandramohan A, Moran B
Int J Hyperthermia 2017 Aug;33(5):511-519. doi: 10.1080/02656736.2017.1310938. PMID: 28540829
Chronic colonic perforation in pseudomyxoma peritonei.
Naidu LS, Jobling JC
Br J Radiol 2007 May;80(953):e94-7. doi: 10.1259/bjr/62059548. PMID: 17638839
Colorectal cancer after pelvic irradiation: case reports.
Tsunoda A, Shibusawa M, Kawamura M, Marumori T, Kusano M, Ohta H
Anticancer Res 1997 Jan-Feb;17(1B):729-32. PMID: 9066610
The malignant potential of colorectal Crohn's disease.
Wyatt MG, Houghton PW, Mortensen NJ, Williamson RC
Ann R Coll Surg Engl 1987 Sep;69(5):196-8. PMID: 2823678Free PMC Article

Therapy

Colorectal carcinoma in children.
Karnak I, Ciftci AO, Senocak ME, Büyükpamukçu N
J Pediatr Surg 1999 Oct;34(10):1499-504. doi: 10.1016/s0022-3468(99)90112-4. PMID: 10549756
Colorectal cancer after irradiation for cervical cancer--case reports.
Kimura T, Iwagaki H, Hizuta A, Nonaka Y, Tanaka N, Orita K
Anticancer Res 1995 Mar-Apr;15(2):557-8. PMID: 7763037
Nd-YAG laser therapy for palliation of obstructed colorectal carcinomas.
Rau BK, Harikrishnan KM, Krishna S
Indian J Cancer 1994 Dec;31(4):240-3. PMID: 7875725

Prognosis

Mesenteric lymph node involvement in advanced ovarian cancer patients undergoing rectosigmoid resection: prognostic role and clinical considerations.
Gallotta V, Fanfani F, Fagotti A, Chiantera V, Legge F, Gueli Alletti S, Nero C, Margariti AP, Papa V, Alfieri S, Ciccarone F, Scambia G, Ferrandina G
Ann Surg Oncol 2014 Jul;21(7):2369-75. Epub 2014 Feb 21 doi: 10.1245/s10434-014-3558-0. PMID: 24558070
Colorectal carcinoma in children.
Karnak I, Ciftci AO, Senocak ME, Büyükpamukçu N
J Pediatr Surg 1999 Oct;34(10):1499-504. doi: 10.1016/s0022-3468(99)90112-4. PMID: 10549756
Colorectal cancer after pelvic irradiation: case reports.
Tsunoda A, Shibusawa M, Kawamura M, Marumori T, Kusano M, Ohta H
Anticancer Res 1997 Jan-Feb;17(1B):729-32. PMID: 9066610
The malignant potential of colorectal Crohn's disease.
Wyatt MG, Houghton PW, Mortensen NJ, Williamson RC
Ann R Coll Surg Engl 1987 Sep;69(5):196-8. PMID: 2823678Free PMC Article
The significance of the signet-cell variety of adenocarcinoma of the rectum.
Bonello JC, Sternberg SS, Quan SH
Dis Colon Rectum 1980 Apr;23(3):180-3. doi: 10.1007/BF02587622. PMID: 6247125

Clinical prediction guides

Different clinical characteristics in sporadic young-age onset colorectal cancer.
Lee J, Kim IH, Kim JS, Kim SW, Kim JG, Oh ST, Kang WK, Lee MA
Medicine (Baltimore) 2016 Sep;95(37):e4840. doi: 10.1097/MD.0000000000004840. PMID: 27631240Free PMC Article
A novel risk-adjusted nomogram for rectal cancer surgery outcomes.
Russell MC, You YN, Hu CY, Cormier JN, Feig BW, Skibber JM, Rodriguez-Bigas MA, Nelson H, Chang GJ
JAMA Surg 2013 Aug;148(8):769-77. doi: 10.1001/jamasurg.2013.2136. PMID: 23803722Free PMC Article
Colorectal carcinoma in children.
Karnak I, Ciftci AO, Senocak ME, Büyükpamukçu N
J Pediatr Surg 1999 Oct;34(10):1499-504. doi: 10.1016/s0022-3468(99)90112-4. PMID: 10549756
Colorectal cancer after pelvic irradiation: case reports.
Tsunoda A, Shibusawa M, Kawamura M, Marumori T, Kusano M, Ohta H
Anticancer Res 1997 Jan-Feb;17(1B):729-32. PMID: 9066610
Colorectal cancer after irradiation for cervical cancer--case reports.
Kimura T, Iwagaki H, Hizuta A, Nonaka Y, Tanaka N, Orita K
Anticancer Res 1995 Mar-Apr;15(2):557-8. PMID: 7763037

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